Abstract：
:The aim of this retrospective study was to determine whether pituitary down-regulation after gonadotrophin-releasing hormone analogue (GnRHa) administration can be accurately predicted by transvaginal ultrasonographic measurement of endometrial thickness in the presence of menstruation. All cycles of an IVF/intracytoplasmic sperm injection programme in which a long protocol of GnRHa was used for ovarian stimulation were analysed. Overall, 209 patients underwent 223 treatment cycles. Using a serum oestradiol concentration of 50 pg/ml as a cut-off point, the sensitivity, specificity, predictive value and false positive and false negative values were calculated for prediction of pituitary down-regulation from endometrial thickness measurements. Pituitary down-regulation was achieved in 223 treatment cycles in 180 patients (80%). The best combination of the highest specificity (71.7%) and sensitivity (62.5%) is achieved with a linear appearance of the endometrium. Therefore, ultrasonographic measurement of endometrial thickness should be used in combination with serum oestradiol concentration in estimating pituitary down-regulation after GnRHa. In conclusion, the linear appearance of endometrium can be as reliable as serum oestradiol concentration in prediction of pituitary down-regulation after GnRHa.
journal_name
Reprod Biomed Onlinejournal_title
Reproductive biomedicine onlineauthors
Dogan MM,Uygur D,Alkan RN,Batioglu S,Mollamahmutoglu Ldoi
10.1016/s1472-6483(10)61109-1keywords:
subject
Has Abstractpub_date
2004-05-01 00:00:00pages
595-9issue
5eissn
1472-6483issn
1472-6491pii
S1472-6483(10)61109-1journal_volume
8pub_type
杂志文章abstract：:This proceedings report presents the outcomes from an international Expert Meeting to establish a consensus on the recommended technical and operational requirements for air quality within modern assisted reproduction technology (ART) laboratories. Topics considered included design and construction of the facility, as...
journal_title：Reproductive biomedicine online
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journal_title：Reproductive biomedicine online
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journal_title：Reproductive biomedicine online
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章
doi：10.1016/j.rbmo.2009.10.001
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abstract：:Clinicians who treat unsuccessful couples despite repeated transfers of good quality embryos face a challenge. Among the various strategies that have been described, embryo transfer at the blastocyst stage has been postulated to improve implantation. A prospective non-randomized analysis was performed in 276 IVF patie...
journal_title：Reproductive biomedicine online
pub_type： 临床试验,杂志文章
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更新日期：2004-12-01 00:00:00
abstract：:In stimulated IVF/intracytoplasmic sperm injection cycles, the luteal phase is disrupted, necessitating luteal-phase supplementation. The most plausible reason behind this is the ovarian multifollicular development obtained after ovarian stimulation, resulting in supraphysiological steroid concentrations and consecuti...
journal_title：Reproductive biomedicine online
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章
doi：10.1016/s1472-6483(10)61284-9
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章
doi：10.1016/s1472-6483(10)60762-6
更新日期：2007-01-01 00:00:00
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journal_title：Reproductive biomedicine online
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章,随机对照试验
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abstract：:Due to inherent differences between gonadotrophin-releasing hormone (GnRH) antagonists and agonists, their late effect on ovarian steroidal production during the luteal phase of IVF cycles may differ. The aim of this study was to characterize and compare the luteal phase hormonal profile after the use of GnRH antagoni...
journal_title：Reproductive biomedicine online
pub_type： 杂志文章,随机对照试验
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journal_title：Reproductive biomedicine online
pub_type： 历史文章,杂志文章
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章,随机对照试验
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更新日期：2007-08-01 00:00:00
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章,评审
doi：10.1016/s1472-6483(10)60659-1
更新日期：2006-11-01 00:00:00
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章
doi：10.1016/j.rbmo.2017.10.107
更新日期：2018-01-01 00:00:00
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章
doi：10.1016/s1472-6483(10)61591-x
更新日期：2002-07-01 00:00:00
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章
doi：10.1016/s1472-6483(10)61975-x
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abstract：:This report aimed to examine the effects of atosiban on pregnancy outcome after IVF-embryo transfer. A prospective, randomized, placebo-controlled clinical study was performed. A total of 180 women undergoing intracytoplasmic sperm injection who had top-quality embryos were randomly allocated into treatment and contro...
journal_title：Reproductive biomedicine online
pub_type： 杂志文章,随机对照试验
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更新日期：2010-09-01 00:00:00
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章,随机对照试验
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abstract：:An effective, consistent and xeno-free cryopreservation technique is crucial for any human embryonic stem cell (hESC) laboratory with future perspectives for clinical application. This study presents a new slow freezing-rapid thawing method in serum-free conditions that allows the cryopreservation of a large number of...
journal_title：Reproductive biomedicine online
pub_type： 杂志文章
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章
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更新日期：2011-02-01 00:00:00
abstract：:Polycystic ovary syndrome (PCOS) is associated with increased risk of impaired glucose tolerance and type 2 diabetes. PCOS has been considered as a major risk factor for the development of diabetes, and screening of women with PCOS for glucose intolerance is suggested. Detection of glucose intolerance in PCOS is best ...
journal_title：Reproductive biomedicine online
pub_type： 杂志文章,评审
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更新日期：2004-06-01 00:00:00
abstract：:The mammalian oocyte is especially sensitive to cryopreservation. Because of its size and physiology, it can easily undergo cell death or sub-lethal damage as a consequence of intracellular ice formation, increase in the concentration of solutes and other undesired effects during the conversion of extracellular water ...
journal_title：Reproductive biomedicine online
pub_type： 杂志文章,评审
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章,meta分析
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更新日期：2006-11-01 00:00:00
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章,评审
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更新日期：2002-01-01 00:00:00
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journal_title：Reproductive biomedicine online
pub_type： 杂志文章
doi：10.1016/j.rbmo.2018.08.015
更新日期：2018-11-01 00:00:00
abstract：RESEARCH QUESTION:Elective single-embryo transfer (eSET) at blastocyst stage is widely used to reduce the frequency of multiple pregnancies after IVF. There are, however, concerns about increased risks for the offspring with prolonged embryo culture. Is it possible to select embryos for transfer at the early cleavage s...
journal_title：Reproductive biomedicine online
pub_type： 杂志文章
doi：10.1016/j.rbmo.2018.09.020
更新日期：2019-01-01 00:00:00
