Abstract：
:This paper reviews and compares individual voxel-wise thresholding methods for identifying active voxels in single-subject fMRI datasets. Different error rates are described which may be used to calibrate activation thresholds. We discuss methods which control each of the error rates at a prespecified level alpha, including simple procedures which ignore spatial correlation among the test statistics as well as more elaborate ones which incorporate this correlation information. The operating characteristics of the methods are shown through a simulation study, indicating that the error rate used has an important impact on the sensitivity of the thresholding method, but that accounting for correlation has little impact. Therefore, the simple procedures described work well for thresholding most single-subject fMRI experiments and are recommended. The methods are illustrated with a real bilateral finger tapping experiment.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Logan BR,Rowe DBdoi
10.1016/j.neuroimage.2003.12.047keywords:
subject
Has Abstractpub_date
2004-05-01 00:00:00pages
95-108issue
1eissn
1053-8119issn
1095-9572pii
S1053811904000096journal_volume
22pub_type
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