Abstract:
BACKGROUND:A beneficial prophylactic effect from eletriptan 40 mg given to a single patient with cluster headache was observed. OBJECTIVE:To further evaluate the efficacy of eletriptan in the short-term prophylaxis of cluster headache. METHODS:We treated 18 patients; mean age, 40.5 years (standard deviation [SD], 9.9). The number of cluster headache attacks was recorded during a baseline period of 6 days, and during 6 days of treatment with eletriptan 40 mg twice daily. The primary outcome measure was the reduction in the number of attacks during the treatment period. RESULTS:In the 16 patients who completed the study (2 patients were lost to follow-up), the mean total number of attacks decreased from 10.9 (SD, 5.6) during baseline to 6.3 (SD, 3.7) during treatment with eletriptan (P=.01) The reduction in the number of attacks exceeded 50% in 6 patients. CONCLUSION:This small open-label study suggests that eletriptan 40 mg twice daily may be useful for the short-term prophylaxis of cluster headache.
journal_name
Headachejournal_title
Headacheauthors
Zebenholzer K,Wöber C,Vigl M,Wessely Pdoi
10.1111/j.1526-4610.2004.04079.xkeywords:
subject
Has Abstractpub_date
2004-04-01 00:00:00pages
361-4issue
4eissn
0017-8748issn
1526-4610pii
HED04079journal_volume
44pub_type
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