Central sensitization theory of migraine: clinical implications.

abstract：:A questionnaire study on headaches, using a door-to-door survey, was carried out in a representative sample of the general Greek population, including 1737 men and 1764 women, from 15 to 75 years of age. The parameters evaluated included age, sex, education, socioeconomic status, region of domicile, frequency of heada...

journal_title：Headache

authors： Mitsikostas DD,Tsaklakidou D,Athanasiadis N,Thomas A

更新日期：1996-03-01 00:00:00

abstract：:Two patients suffering from SUNCT syndrome are presented. Some features are remarkable. The first patient was a 69-year-old man whose first crisis was located in the right supraorbital region. After a 4-month spontaneous remission, the pain returned to the upper part of the cheek, radiating to the supraciliary region ...

journal_title：Headache

authors： Raimondi E,Gardella L

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Many children suffering from chronic headache and migraine present with comorbid functional disability, including physical, social, emotional, and academic activities. For children severely impaired by headache, intensive interdisciplinary pain rehabilitation treatment (IIPT) can improve functioning. However...

journal_title：Headache

authors： Benore E,Webster EE,Wang L,Banez G

更新日期：2018-11-01 00:00:00

abstract：:The efficacy of the repetitive intravenous dihydroergotamine (DHE) inpatient protocol for refractory headache is well established. We conducted a retrospective and prospective study of long-term headache patients at our clinic to evaluate this regimen in an outpatient setting. Treatment consisted of oral metoclopramid...

journal_title：Headache

authors： Robbins L,Remmes A

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:A new form of headache, Headache attributed to aeroplane travel (AH), has been recognized within the International Classification of Headache Disorders 3 beta (ICHD-3beta). In 8 out of 85 AH cases we identified the coexistence of a headache with identical features of AH, but appearing during the rapid descen...

journal_title：Headache

authors： Mainardi F,Maggioni F,Zanchin G

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:Our study aims to examine factors related to access of triptans among multiple stakeholder groups. BACKGROUND:Triptans are a cornerstone of pain management for the acute treatment of migraine, but actual utilization of triptans is lower than ideal. Initial and continued access to triptans may be an important...

journal_title：Headache

authors： Khan S,Mascarenhas A,Moore JE,Knowles S,Gomes T

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To assess physician-patient communication about headache-related disability and to evaluate the influence of information about disability on physicians' perceptions of illness severity and the treatment needs of migraineurs. BACKGROUND:Evidence suggests that migraine is suboptimally treated in clinical pract...

journal_title：Headache

authors： Holmes WF,MacGregor EA,Sawyer JP,Lipton RB

更新日期：2001-04-01 00:00:00

abstract：:Seventeen patients with migraine headaches, occurring at least twice a month, were successfully treated with an ACE inhibitor for prophylaxis. Most were given enalapril, some used lisinopril. Duration of treatment ranged from 3 months to 3 years. Side effects were generally not noted. Cough occurred in four patients. ...

journal_title：Headache

authors： Bender WI

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between hyposerotonin and cranial microvascular responses to nitric oxide (NO). BACKGROUND:Although the mechanism underlying NO supersensitivity in migraine is still unclear, an alteration of the serotonin system is a possible explanation. METHODS:Wistar rats were divided int...

journal_title：Headache

authors： Srikiatkhachorn A,Anuntasethakul T,Maneesri S,Phansuwan-Pujito P,Patumraj S,Kasantikul V

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To establish if criteria for the diagnosis of migraine change with age and to document the influence of age on the full spectrum of migraine features. Also to define the clinical spectrum and provide a prognostic profile of migraine stratified by age. BACKGROUND:Few studies have formally analyzed migraine ch...

journal_title：Headache

authors： Kelman L

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Subcutaneous (s.c.) injection of sumatriptan is currently associated with needle aversion in some patients, and sharps disposal issues. OBJECTIVES:To investigate whether a needle-free system can deliver s.c. sumatriptan. If so, to examine whether needle-free administration is bioequivalent to a 26-gauge nee...

journal_title：Headache

authors： Brandes JL,Cady RK,Freitag FG,Smith TR,Chandler P,Fox AW,Linn L,Farr SJ

更新日期：2009-11-01 00:00:00

abstract：:Greater occipital nerve (GON) infiltration is widely used for the treatment of primary and secondary headache disorders mainly on the basis of open-label evidence, although recent double-blinded placebo-controlled trials have demonstrated its efficacy in cluster headache. The procedure is generally well tolerated alth...

journal_title：Headache

authors： Lambru G,Lagrata S,Matharu MS

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Neuromodulators such as topiramate (TPM) and divalproex sodium (DVS) are effective in the preventive treatment of migraine. Nonetheless, patients often discontinue their use due to side effects. OBJECTIVES:The study aims to determine whether the combination of lower doses of TPM and DVS may be useful for pa...

journal_title：Headache

authors： Krymchantowski AV,Jevoux Cda C

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To assess the acute treatment of pregnant women presenting to a hospital with migraine. BACKGROUND:Migraine is a common problem in pregnancy; however, migraine treatment is challenging in pregnant women for fears of medication teratogenicity and lack of data in this population. To date, no study has directly...

journal_title：Headache

authors： Hamilton KT,Robbins MS

更新日期：2019-02-01 00:00:00

abstract：:We performed greater occipital nerve blocks on 24 migraineurs with unilateral migraine and trigeminal nerve distribution allodynia. Using a visual analog scale for migraine pain, brush allodynia in the trigeminal nerve distribution and photophobia were reduced 64%, 75%, and 67%, respectively, after 5 minutes. Allodyni...

journal_title：Headache

authors： Young W,Cook B,Malik S,Shaw J,Oshinsky M

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVES:In a randomized controlled trial extending over 6 months, we evaluated the effectiveness of acupuncture versus flunarizine in the prophylactic treatment of migraine without aura. METHODS:One hundred sixty women with migraines were randomly assigned to acupuncture treatment (group A, n = 80) or to an oral th...

journal_title：Headache

authors： Allais G,De Lorenzo C,Quirico PE,Airola G,Tolardo G,Mana O,Benedetto C

更新日期：2002-10-01 00:00:00

abstract：:Interictal serum levels of serotonin and plasma and mononuclear cell concentrations of beta-endorphin were measured in 20 juvenile patients (13 suffering from migraine without aura and 7 from episodic tension-type headache) before and after 3 months of L-5-hydroxytryptophan treatment (5 mg/kg/day) and compared with a ...

journal_title：Headache

authors： Battistella PA,Bordin A,Cernetti R,Broetto S,Corrà S,Piva E,Plebani M

更新日期：1996-02-01 00:00:00

abstract：:More than 60 years ago Aristides Leão coined the term spreading depression (SD) to describe a transient "depression" of electrocorticographic activity that lasts up to several minutes and slowly "spreads" in all directions in cortex by way of gray matter contiguity.(1) Today we know that SD is an intrinsic electrophys...

journal_title：Headache

authors： Ayata C

更新日期：2010-04-01 00:00:00

abstract：:While headache is a documented side effect of electroconvulsive therapy (ECT), there is little information on this phenomenon. Studies of the mechanisms of ECT as a treatment for depression indicate that alterations in serotonergic neurotransmission appear to be related to its efficacy. While ECT and many of the antid...

journal_title：Headache

authors： Weiner SJ,Ward TN,Ravaris CL

更新日期：1994-03-01 00:00:00

abstract：:Orthostatic headache is a key symptom of intracranial hypotension; however, not all orthostatic headaches are caused by cerebrospinal fluid leaks leading to intracranial hypotension. We report here the unusual case of a 68-year-old man presenting with orthostatic headache in which compression of the C3 spinal nerve ro...

journal_title：Headache

authors： Kim JH,Choi JY,Kim HJ,Oh K

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:To determine the 1-year prevalence of headache and clinical characteristics of primary headaches among school children in South Korea. BACKGROUND:Many population-based studies have estimated the 1-year prevalence of headache, migraine, and tension-type headache (TTH). The results of those studies vary in te...

journal_title：Headache

authors： Rho YI,Chung HJ,Lee KH,Eun BL,Eun SH,Nam SO,Kim WS,Kim YO,Park HJ,Kim HS

更新日期：2012-04-01 00:00:00

abstract：:This review considers current debate surrounding refractory migraine and poses the question, why do some patients fail to improve with currently available therapies? ...

journal_title：Headache

authors： Dodick DW

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Zonisamide, a sulfonamide analog, is an antiepileptic drug with mechanisms of action similar to topiramate. Because of its pharmacodynamic and pharmacokinetics profiles, zonisamide is also potentially suitable for migraine prevention. METHODS:Tolerability and effectiveness of zonisamide for migraine prophyl...

journal_title：Headache

authors： Villani V,Ciuffoli A,Prosperini L,Sette G

更新日期：2011-02-01 00:00:00

abstract：:Questions about discomfort or pain produced by various stimuli (e.g., light, sound, exercise, neck movements) are currently used to differentiate between various primary headache disorders. In order to evaluate the usefulness of differences in sensitivity to physical stimuli in headache diagnosis, the answers to a que...

journal_title：Headache

authors： Vingen JV,Sand T,Stovner LJ

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Mechanical compression of the trigeminal root by an artery is thought to cause trigeminal neuralgia. The 5-HT(1B/1D) receptor agonist may inhibit neurogenic inflammation and vasodilation near the irritated trigeminal root. OBJECTIVE:To examine the effectiveness of a 5-HT(1B/1D) receptor agonist, sumatriptan...

journal_title：Headache

authors： Kanai A,Saito M,Hoka S

更新日期：2006-04-01 00:00:00

abstract：:A subcutaneous injection of 6 mg sumatriptan rapidly and effectively stopped attacks of cluster headache. After a time lag of 4-14 minutes (mean 7 minutes) pain dramatically dropped to zero within seconds to single minutes (mean 56 seconds). This rapid effect may indicate that mere vasoconstriction is the mechanism be...

journal_title：Headache

authors： Hardebo JE

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the safety and efficacy of ketamine-magnesium combination to reduce attacks in a series of patients with refractory chronic cluster headache (rCCH). BACKGROUND:Refractory chronic cluster headache (CCH) is a rare but highly debilitating condition that needs new treatment options. A previous publi...

journal_title：Headache

authors： Moisset X,Giraud P,Meunier E,Condé S,Périé M,Picard P,Pereira B,Ciampi de Andrade D,Clavelou P,Dallel R

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To investigate differences in topographical pressure pain sensitivity maps of the scalp between patients with migraine and healthy controls considering the chronicity (episodic/chronic) and side (strictly unilateral/bilateral) of the symptoms. BACKGROUND:It seems that the trigeminal area is sensitized in mig...

journal_title：Headache

authors： Barón J,Ruiz M,Palacios-Ceña M,Madeleine P,Guerrero ÁL,Arendt-Nielsen L,Fernández-de-Las-Peñas C

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:To compare, using a within-woman analysis, the severity, duration, and relapse of menstrual vs nonmenstrual episodes of migraine during treatment with usual migraine therapy. BACKGROUND:Studies comparing the clinical characteristics of menstrual and nonmenstrual migraine attacks have yielded conflicting resu...

journal_title：Headache

authors： MacGregor EA,Victor TW,Hu X,Xiang Q,Puenpatom RA,Chen W,Campbell JC

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Though thyroid growths are considered to be a frequent cause of Horner's syndrome, concurrent headache attacks are not commonly seen. CASE:A 63-year-old woman presented with severe, daily occurring, unilateral headache attacks with ipsilateral Horner's syndrome. Magnetic resonance imaging arteriography show...

journal_title：Headache

authors： Smit RA,Treurniet FE,Koppen H

更新日期：2014-09-01 00:00:00