Abstract:
OBJECTIVE:To determine if the use of a uniform treatment pathway might be effective in treating patients with primary chronic daily headache. METHODS:Thirty-three consecutive patients with primary chronic daily headache were managed according to a treatment pathway which involved sequential administration of divalproex sodium, amitriptyline, amitriptyline plus phenelzine, or methadone. RESULTS:Twenty-two patients (67%) reported a 50% or greater reduction in headache days per month following initiation of treatment. Most positive treatment responses (17 [77%] of 22) were attributed to divalproex sodium. CONCLUSION:Implementation of a uniform treatment pathway may result in significant clinical improvement in a sizable proportion of patients with chronic daily headache.
journal_name
Headachejournal_title
Headacheauthors
Rothrock JFdoi
10.1046/j.1526-4610.1999.3909650.xkeywords:
subject
Has Abstractpub_date
1999-10-01 00:00:00pages
650-3issue
9eissn
0017-8748issn
1526-4610journal_volume
39pub_type
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