One-year follow-up of headache in an adult general population.

abstract：:The drug discovery programs that led to the development of the triptans were determined by the membership of the American Headache Society to be the most important breakthrough in headache medicine in the last 50 years. Dr. Humphrey, who spearheaded the drug discovery, recounts the pioneering work that took place and ...

journal_title：Headache

authors： Humphrey PP

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To assess the effect of aspirin on platelet reactivity in migraineurs. BACKGROUND:Migraineurs, particularly women with aura and high monthly migraine frequency, are at risk for ischemic stroke and myocardial infarction (MI). High on-aspirin platelet reactivity (HAPR), or aspirin resistance, has been reported...

journal_title：Headache

authors： Jesurum JT,Fuller CJ,Murinova N,Truva CM,Lucas SM

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Lidocaine, an amide anesthetic, has been used in the treatment of a wide variety of pain disorders for over 75 years. In addition to pain control, lidocaine is an anti-arrhythmic agent and has anti-inflammatory properties. Lidocaine's unique properties, including nonlinear pharmacokinetics, have limited its ...

journal_title：Headache

authors： Berk T,Silberstein SD

更新日期：2018-05-01 00:00:00

abstract：:Cyclic AMP (CAMP) accumulation induced by isoproterenol (IP) and forskolin in intact lymphocytes was determined in 12 patients with migraine and 12 healthy controls. Our data showed that IP CAMP accumulation (8.20 + 1.08 Pmol/million cells) was significantly (P = 0.033) lower than accumulation in the controls (14.39 +...

journal_title：Headache

authors： Kuritzky A,Bennet E,Hering R,Ebstein R

更新日期：1993-04-01 00:00:00

abstract：:Consumption of monosodium glutamate has long been considered to precipitate headaches in susceptible patients. In this study the direct effects of glutamate and its metabolite, glutamine, on arterial contractility were examined using rings of rabbit aorta. In a high concentration glutamate caused significant concentra...

journal_title：Headache

authors： Merritt JE,Williams PB

更新日期：1990-09-01 00:00:00

abstract：OBJECTIVE:Using a "double-pulse" adaptation paradigm, in which two stimuli are presented in quick succession, this study examines the neural mechanisms underlying potentiation of the visual evoked potential (VEP) in visual snow syndrome. BACKGROUND:Visual snow is a persistent visual disturbance characterized by rapid ...

journal_title：Headache

authors： Luna S,Lai D,Harris A

更新日期：2018-01-01 00:00:00

abstract：:The symptoms of migraine are non-specific and can be present in many other primary and secondary headache disorders, which are reviewed. Even experienced headache specialists may be challenged at times when diagnosing what appears to be first or worst, new type, migraine status, and chronic migraine. ...

journal_title：Headache

authors： Evans RW

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the prevalence of migraine/severe headaches in those with and without general obesity and abdominal obesity (Abd-O) and the effect of gender and age on this relationship. BACKGROUND:General, or total body obesity (TBO), as estimated by body mass index, is a risk factor for migraine chronification...

journal_title：Headache

authors： Peterlin BL,Rosso AL,Rapoport AM,Scher AI

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Though triptans are considered the standard of acute therapy for migraine attacks with headache-related disability, they are used by the minority of potentially eligible persons. Understanding the socio-demographic and headache features that predict triptan use may help to clarify barriers to optimal treatme...

journal_title：Headache

authors： Chu MK,Buse DC,Bigal ME,Serrano D,Lipton RB

更新日期：2012-02-01 00:00:00

abstract：:The typical symptom of intracranial hypotension syndrome is orthostatic headache. The headache may also be accompanied by neck pain and stiffness, low backache, radicular symptoms, quadriplegia, interscapular pain, nausea/vomiting, and cranial nerve involvement symptoms (hearing and visual problems, face pain and numb...

journal_title：Headache

authors： Albayram S,Asik M,Hasiloglu ZI,Dikici AS,Erdemli HE,Altintas A

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Headache is commonly reported in patients presenting with orofacial pain. It has only recently been demonstrated that headache-related disability is high in orofacial pain patients. Traumatic life events (TLEs) such as sexual abuse, physical abuse, and post-traumatic stress disorder (PTSD) are also common in...

journal_title：Headache

authors： Branch MA

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To evaluate whether self-reported past migraine response to reproductive life events (menses, pregnancy, menopause) alters the likelihood of worsening of migraine with exogenous hormone use. METHODS:A retrospective study was conducted on 451 female patients at the University Headache Center who had a diagnos...

journal_title：Headache

authors： Mueller L

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE AND BACKGROUND:Pupillometric investigations into migraine have suggested that an autonomic disturbance is part of the pathogenesis of that condition. This observation is controversial, however, which may reflect that the putative sympathetic hypofunction is either subtle or transient. In this study, we assess...

journal_title：Headache

authors： Cambron M,Maertens H,Paemeleire K,Crevits L

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:In previous studies, pregnancy has been associated with less headache, but the influence of parity on this association is largely unknown. OBJECTIVES:To examine the prevalence of headache and migraine among pregnant women, and explore the relation of headache to parity in a large, population-based study. M...

journal_title：Headache

authors： Aegidius K,Zwart JA,Hagen K,Stovner L

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Recent studies have found a strong relationship between tobacco smoking and headache pain. It remains unclear whether smoking behavior leads to headache or visa versa, mainly due to the cross-sectional nature of the majority of this research. OBJECTIVE:To help clarify the direction of the relation between s...

journal_title：Headache

authors： Waldie KE,McGee R,Reeder AI,Poulton R

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:The pathophysiology of chronic migraine (CM) is not fully understood. We aimed to examine transcranial magnetic stimulation (TMS) indices of cortical excitability in patients with CM and also performed PET studies to ascertain if there were any areas of activation and inhibition for possible correlation. ME...

journal_title：Headache

authors： Aurora SK,Barrodale PM,Tipton RL,Khodavirdi A

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:It is commonly known that headaches are induced by intake of specific food, drink, and/or additive. In addition, some patients experience postprandial headache independent of ingestion of specific items. Currently, information on the pathophysiology underlying this particular type of headache is scarce. CAS...

journal_title：Headache

authors： Takizawa T,Shibata M,Hiraide T,Seki M,Takahashi S,Suzuki N

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Migraine has been reported as a possible risk factor for ischemic stroke. The mechanisms underlying this association are unknown. OBJECTIVES:To evaluate cerebrovascular reactivity to hypercapnia in the anterior and posterior circulation of patients with migraine, as reduced cerebrovascular reactivity is ass...

journal_title：Headache

authors： Silvestrini M,Baruffaldi R,Bartolini M,Vernieri F,Lanciotti C,Matteis M,Troisi E,Provinciali L

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To examine the likelihood of response with continued galcanezumab treatment in patients with episodic or chronic migraine without initial clinical improvement. BACKGROUND:A percentage of patients with migraine may require additional time on pharmacotherapy but discontinue treatment prematurely. Additionally,...

journal_title：Headache

authors： Nichols R,Doty E,Sacco S,Ruff D,Pearlman E,Aurora SK

更新日期：2019-02-01 00:00:00

abstract：:A 57-year-old woman presented with an escalation of her headaches which ultimately progressed to multiple strokes and death. MRI/MRA demonstrated diffuse vasospasm and other causes of stroke were excluded on premortem investigation and postmortem examination. Reversible MRI abnormalities, vasospasm on angiogram and fa...

journal_title：Headache

authors： Marshall N,Maclaurin WA,Koulouris G

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a sympathetic block at C7 on cluster headache. BACKGROUND:Eleven patients presenting to a pain control unit with cluster headache were included in the study after giving informed consent. METHODS:In all patients, a mixture of 5 mL of 0.5% bupivacaine hydrochloride and 1 cc of meth...

journal_title：Headache

authors： Albertyn J,Barry R,Odendaal CL

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To examine the efficacy of L-kynurenine and a novel kynurenic acid derivative on the nitroglycerin-induced calmodulin-dependent protein kinase II alpha (CamKIIalpha) and calcitonin gene-related peptide (CGRP) expression changes in the rat caudal trigeminal nucleus. BACKGROUND:Systemic administration of the n...

journal_title：Headache

authors： Vámos E,Fejes A,Koch J,Tajti J,Fülöp F,Toldi J,Párdutz A,Vécsei L

更新日期：2010-05-01 00:00:00

abstract：:Two adults presented with new-onset migrainous-type visual disturbances and had angiographically demonstrated filling defects near the torcular Herophili. Neither patient had a visual field deficit nor cerebral computed tomography evidence of an occipital infarction. The association of migraine-like visual phenomena w...

journal_title：Headache

authors： Newman DS,Levine SR,Curtis VL,Welch KM

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVES:To compare the relative tolerability of 5-HT1B/1D agonists and to investigate the relationships (if any) among systemic exposure, lipophilicity, and clinical tolerability for 5-HT1B/1D agonists. METHODS:Post hoc correlations were sought among the following variables: absolute dose (= administered dose x ora...

journal_title：Headache

authors： Fox AW

更新日期：2000-07-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) is a ubiquitous neuropeptide found at the very centers of the migraine process, both centrally and peripherally. It has been under careful study for approximately 25 years. Several CGRP-receptor antagonists are being evaluated for acute treatment of episodic migraine. Three monoc...

journal_title：Headache

authors： Bigal ME,Walter S,Rapoport AM

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Erenumab, a calcitonin gene-related peptide (CGRP) receptor monoclonal antibody, has been well tolerated with good efficacy for the preventive treatment of episodic and chronic migraine in phase 2 and phase 3 clinical trials. Limited post-market observations are available to validate these findings in a real...

journal_title：Headache

authors： Robblee J,Devick KL,Mendez N,Potter J,Slonaker J,Starling AJ

更新日期：2020-10-01 00:00:00

abstract：:In order to study the frequency and characteristics of post-angiography headache, we interviewed 45 consecutive patients (mean age +/- SD = 57 +/- 15 years; M/F = 15/30) who underwent transfemoral cerebral angiography for: ischemic cerebrovascular disease (n = 33); suspected arteriovenous malformations (n = 4; one con...

journal_title：Headache

authors： Ramadan NM,Gilkey SJ,Mitchell M,Sawaya KL,Mitsias P

更新日期：1995-01-01 00:00:00

abstract：:In a questionnaire survey we determined the prevalence of problems with reading, at present as well as in the past, in adult chronic headache sufferers as compared with age- and sex-matched controls. The reading problems inquired about were those with reading in general, reading quickly, prolonged reading and reading ...

journal_title：Headache

authors： Cremins JJ,Spierings EL,Meltzer LJ,Messinger HB,Lebbink J

更新日期：1991-04-01 00:00:00

abstract：:This study examined the relationship between the menstrual cycle, the stress process, and migraines. Women migraineurs (N = 12) and a matched control sample (N = 12) completed a set of questionnaires assessing stress, appraisal, and coping at premenses, menses, and ovulation. In addition, migraineurs completed a month...

journal_title：Headache

authors： Holm JE,Bury L,Suda KT

更新日期：1996-10-01 00:00:00

abstract：:Migraine and stroke are the most common neurovascular disorders affecting adults. Migraine, particularly with aura, is associated with increased stroke risk both during and between attacks; as such, migraine may be viewed as a potentially modifiable risk factor for stroke. The exact mechanism by which migraine can pre...

journal_title：Headache

authors： Alhazzani A,Goddeau RP

更新日期：2013-06-01 00:00:00