Abstract：
:Arteriovenous malformation (AVM) may change the cerebral hemodynamics. The purpose of this study was to detect the effects of ionizing radiation (IR) on tissues surrounding AVM in a rat caroticojugular fistula model. Forty rats were divided into four groups. Eight weeks after caroticojugular fistulas and chronic hypoperfusion were created in groups 1 and 2, IR was administered to groups 1 and 3. Group 4 was the control. Brain tissue samples were taken 72 h after irradiation. Comet assay to detect DNA strand breaks (DSB), terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate-biotin nick end labeling (TUNEL) assay for apoptosis, and free radical measurement were performed. Although the difference between fistula plus irradiation (group 1) and fistula (group 2) was statistically insignificant in terms of DSB and free radical measurement, apoptotic cell count was significantly higher in group 1. Nonetheless, apoptotic cell count corresponded well with both free radicals and DSB in the irradiated group (group 3). Ionizing radiation resulted in significant apoptosis in both groups with or without fistulas. Chronic hypoperfusion might not prevent cerebral damage after IR. Optimal care should be taken with brain tissue around AVM during radiotherapy, regardless of presence or absence of the "steal" phenomenon.
journal_name
Neurosurg Revjournal_title
Neurosurgical reviewauthors
Mut M,Oge K,Zorlu F,Undeğer U,Erdem S,Ozcan OEdoi
10.1007/s10143-003-0316-3keywords:
subject
Has Abstractpub_date
2004-04-01 00:00:00pages
121-7issue
2eissn
0344-5607issn
1437-2320journal_volume
27pub_type
杂志文章abstract：:80-90% of individuals suffering from aneurysmal bone cyst (ABC) are children or adolescents. Primary ABC is a non-neoplastic lesion. Diagnostic assessment and detection of recurrence demands repeated plain x-rays or CT scans. These repeated radiographic examinations expose these young patients to large doses of ionizi...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF00383659
更新日期：1990-01-01 00:00:00
abstract：:A primary xanthomatous tumor is very rare in the central nervous system (CNS). Here we report the case of a fibroxanthoma arising from the dura mater of the cerebrum that demonstrated no systemic disease or metabolic abnormalities. A 19-month-old, otherwise healthy boy was found to have an enlarged head. Magnetic reso...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s101430050019
更新日期：1999-12-01 00:00:00
abstract：:Residual and recurrent intracranial aneurysms after surgical clipping present a persistent risk of bleeding. Secondary coiling after incomplete clipping represents a strategy to occlude the residual sac: feasibility, bleeding risk and outcome were evaluated through a systematic review of literature along with the seri...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-018-0950-4
更新日期：2019-06-01 00:00:00
abstract：:Hemodynamic parameters play a significant role in the development of cerebral aneurysms. Parameters such as wall shear stress (WSS) or velocity could change in time and may contribute to aneurysm growth and rupture. However, the hemodynamic changes at the rupture location remain unclear because it is difficult to obta...
journal_title：Neurosurgical review
pub_type： 杂志文章,评审
doi：10.1007/s10143-016-0795-7
更新日期：2017-04-01 00:00:00
abstract：:Concordance between the Unruptured Intracranial Aneurysm Treatment Score (UIATS), Earlier Subarachnoid Hemorrhage, Location, Age, Population, Size, Shape (ELAPSS) score, and Population, Hypertension, Age, Size, Earlier Subarachnoid Hemorrhage, Site (PHASES) score with real-world management decisions in unruptured intr...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-020-01356-6
更新日期：2020-07-22 00:00:00
abstract：:Three unusual cases of combined intraorbital-intracranial tumors of various types which were chosen from cases treated in the Clinic and Polyclinic of Neurosurgery of the University of Münster, to demonstrate the problems of surgical therapy. A list of indications for the various accesses to the orbita is worked out. ...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF01794676
更新日期：1988-01-01 00:00:00
abstract：:Surgery is the only therapeutic option for cerebral cavernous malformations (CCM) and is proposed, whenever possible, after haemorrhagic events, neurological symptoms, or epilepsy, radiosurgery being a controversial alternative in some cases. However, there is no treatment for non-accessible lesions, such as brainstem...
journal_title：Neurosurgical review
pub_type： 杂志文章,评审
doi：10.1007/s10143-018-01074-0
更新日期：2019-06-01 00:00:00
abstract：:Colloid cysts of the third ventricle are considered as benign lesions. The clinical manifestations are not clear in most of cases. Many treatment options are available and endoscopic removal of the cysts proves to be a very successful method especially if the lateral ventricles are moderately or severely dilated. Some...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-018-0956-y
更新日期：2019-03-01 00:00:00
abstract：:5-aminolevulinic acid (5-ALA) is a natural precursor of protoporphyrin IX (PP IX), which possesses fluorescent properties and is more intensively accumulated in tumor cells than in normal tissue. Therefore, the use of 5-ALA in the surgical treatment of intracranial tumors, particularly gliomas, has gained popularity i...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-015-0697-0
更新日期：2016-07-01 00:00:00
abstract：:Generally speaking, the term "ophthalmic aneurysms" refers to carotid-ophthalmic aneurysms, which arise from the internal carotid artery (ICA) wall at or around the origin of the ophthalmic artery (OA). In contrast, aneurysms arising from the OA stem or its branches, separate from the ICA are called peripheral OA aneu...
journal_title：Neurosurgical review
pub_type： 杂志文章,评审
doi：10.1007/s10143-010-0290-5
更新日期：2011-01-01 00:00:00
abstract：:Experimental brain tumours were produced in cats by stereotactic implantation of 4 million suspended cells of a rat glioma clone into the internal capsule. Three weeks after implantation a spherical tumour developed with a diameter of up to 10 mm which was surrounded by vasogenic white matter oedema. In untreated anim...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF01743708
更新日期：1981-01-01 00:00:00
abstract：:Cerebral infarction (CI) associated with clipping of unruptured intracranial aneurysms (UIAs) has not been completely studied. The role of individual and operative characteristics is not known, and the risk of silent CI has not been well described. To determine the incidence, risk factors, and clinical outcome of post...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-017-0913-1
更新日期：2018-04-01 00:00:00
abstract：:Despite increasing experience and improved material, endovascular treatment of cerebral aneurysms still has risks linked to the technique itself and to the specificity of the pathology treated. The purpose of this report is to examine procedural technical and clinical negative events, even minimal ones, occurring in t...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-006-0059-z
更新日期：2007-04-01 00:00:00
abstract：:Surgical access to deep intracranial lesions causing the least amount of iatrogenic trauma to the surrounding brain tissue remains a challenging task. In this article, we evaluate the use of a set of sequential tubes that dilate and provide retraction of the overlying brain tissue acting as a surgical corridor for dee...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-012-0442-x
更新日期：2013-04-01 00:00:00
abstract：:We present 78 patients with spinal cord injuries. Operation is not indicated in cord contusion, extended bleeding into the spinal canal or severe fracture dislocation. However, it would seem advisable to operate on patients with vertebral fractures, particularly at the lower thoracic and lumbar levels, if intraspinal ...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF01790702
更新日期：1989-01-01 00:00:00
abstract：:The present study aimed to determine the clinical presentation, the multimodal interdisciplinary treatment strategies and outcome of posterior fossa arterio-venous malformations (AVMs) in our neurovascular centre. Fifty-three patients with a posterior fossa AVM were seen between 1998 and 2012 and analysed retrospectiv...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-014-0551-9
更新日期：2014-10-01 00:00:00
abstract：:Preoperative prediction of molecular information of lower-grade gliomas (LrGGs) helps to determine the overall treatment strategy as well as the initial surgical strategy. This study aimed to detect magnetic resonance imaging (MRI) texture parameters to predict the molecular signature of LrGGs using a commercially ava...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-019-01157-6
更新日期：2020-08-01 00:00:00
abstract：:Superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis is a safe and effective treatment for moyamoya disease, although recent evidence suggests its substantial risk for symptomatic cerebral hyperperfusion. The diagnostic value of single-photon emission computed tomography (SPECT) for postoperative h...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-008-0147-3
更新日期：2008-10-01 00:00:00
abstract：:The purpose of this study was to study the acute phase effects of adenosine triphosphate (ATP)-MgCl2 on experimental spinal cord clip compression injury. Spinal cord clip compression injury was performed on 36 albino Wistar rats. The rats were divided into five groups. T4-T8 total laminectomy was performed on all rats...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-002-0233-x
更新日期：2003-01-01 00:00:00
abstract：:Microcystic meningioma (MM) is a rare subtype of intracranial meningiomas, with clinical and radiologic features not well characterized in the literature. Based on our experience, we propose a classification system of intracranial MMs. We reviewed the medical records, radiographic studies, and operative notes of a gro...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-018-0982-9
更新日期：2019-06-01 00:00:00
abstract：:Acute intracranial subdural hematoma (ASDH) is commonly associated with a grave prognosis citing a high incidence of morbidity and mortality. The parameters to decide on surgical evacuation of the hematoma are sometimes controversial. In this study, we theorized that the ratio between maximal hematoma thickness and mi...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-017-0873-5
更新日期：2018-04-01 00:00:00
abstract：:Although endovascular or surgical treatment has been performed for preventing the rupture of saccular cerebral aneurysms (sCA), in some patients, the aneurysms may recur and require retreatment. We aimed to investigate the clinical and radiological outcomes of treating recurrent sCA. We retrospectively evaluated the d...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-020-01259-6
更新日期：2020-02-21 00:00:00
abstract：:The purpose of this paper is to provide a comprehensive review encompassing the syndromes associated with the lower cranial nerves (LCNs). We will discuss the anatomy of some of these syndromes and the historical contributors after whom they were named. The LCNs can be affected individually or in combination, since th...
journal_title：Neurosurgical review
pub_type： 杂志文章,评审
doi：10.1007/s10143-020-01344-w
更新日期：2020-07-08 00:00:00
abstract：:Solitary brain affection is rare in echinococcosis. We report the case of a 35-year-old woman presenting with symptomatic grand-mal epilepsy due to a right frontal, partially cystic space-occupying lesion. Pre-operative computed tomography and magnetic resonance imaging (MRI) suggested a cystic astrocytoma. However, h...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s101430050011
更新日期：1999-01-01 00:00:00
abstract：:In neurosurgical operations, proper craniotomy using retractors is necessary. Various surgical instruments are used for this purpose, including standard retractors and multipurpose head frame retractor systems. However, the conventional multipurpose head frame system is often not optimal for use in some craniotomies a...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-020-01237-y
更新日期：2020-01-11 00:00:00
abstract：:The basic principles of NMRI are explained. Examples are given of the current medical uses of imaging with protons and other nuclei as well. Further developments towards spectroscopic imaging are discussed. ...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF01892908
更新日期：1984-01-01 00:00:00
abstract：:Giant cavernous hemangiomas occur very rarely, and little has been reported about their behavior. In this case report three cavernous hemangiomas with a diametric measure between 6 cm and 7 cm and distinct features will be described. A 36-year-old female patient presented with headache and nausea. A CT scan disclosed ...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-006-0042-8
更新日期：2007-01-01 00:00:00
abstract：:Skull base chordomas represent very interesting neoplasms, due to their rarity, biological behavior, and resistance to treatment. Their management is very challenging. Recently, the use of a natural corridor, through the nose and the sphenoid sinus, improved morbidity and mortality allowing also for excellent removal ...
journal_title：Neurosurgical review
pub_type： 临床试验,杂志文章
doi：10.1007/s10143-013-0503-9
更新日期：2014-04-01 00:00:00
abstract：:Homocysteine (tHcy) has been hardly studied among patients with head injury. This study was to evaluate whether there is any independent impact of tHcy levels on neurological outcome following head injury in a multivariate model. Patients admitted within 24 h of injury were included in the study, along with 20 age- an...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-017-0880-6
更新日期：2018-04-01 00:00:00
abstract：:A unique case of suprasellar dermoid cyst and familial hypercholesterolemia in a child is reported. Such an association, which strengthens the congenital hypothesis of dermoid cysts, could be a manifestation of a complex dyslipidemic inherited syndrome, at least in children. Surgical removal of the dermoid cyst which ...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF00416478
更新日期：1995-01-01 00:00:00
