Insulin: an endogenous cardioprotector.

abstract：PURPOSE OF REVIEW:In this review, we focus on the dual face of antibiotic therapy in the critically ill that must harmonize the need for early, appropriate and adequate antibiotic therapy in the individual-infected patient with the obligation to limit antibiotic selection pressure as much as possible to preserve its fu...

journal_title：Current opinion in critical care

authors： Depuydt P,De Waele JJ

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Prerenal failure is used to designate a reversible form of acute renal dysfunction. However, the terminology encompasses several different conditions that vary considerably. The lack of a widely accepted definition for prerenal failure makes it impossible to determine the epidemiology, natural history...

journal_title：Current opinion in critical care

authors： Macedo E,Mehta RL

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the role of microcirculatory abnormalities in critically ill patients and the link between systemic hemodynamics and microvascular perfusion. RECENT FINDINGS:Microcirculatory alterations have been repeatedly observed in patients with severe sepsis, but recent findings show that these also ...

journal_title：Current opinion in critical care

authors： De Backer D,Ortiz JA,Salgado D

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the current knowledge about clinical and microbiological diagnosis of nonventilated hospital-acquired pneumonia (NV-HAP). RECENT FINDINGS:NV-HAP is emerging as a new challenge for clinicians, particularly because VAP incidence has been decreasing. The clinical diagnosis of NV-HAP uses the...

journal_title：Current opinion in critical care

authors： Ranzani OT,De Pascale G,Park M

更新日期：2018-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review intends to summarize the recent findings regarding the presence of increased oxidative stress in critically ill patients and its potential pathophysiologic role, as well as the results of recent clinical trials of antioxidant therapies. RECENT FINDINGS:Several lines of evidence confirm th...

journal_title：Current opinion in critical care

authors： Lovat R,Preiser JC

更新日期：2003-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the perioperative monitoring tools and targets for haemodynamic optimization and to assess the influence of goal-directed therapy (GDT) on organ function, complications and outcome in different categories of surgical patients. RECENT FINDINGS:The choice of perioperative haemodynamic monito...

journal_title：Current opinion in critical care

authors： Kirov MY,Kuzkov VV,Molnar Z

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews and critiques new developments in the critical care of burn patients. RECENT FINDINGS:The practice of restrictive transfusion is slowly gaining traction. Abdominal compartment syndrome is associated with resuscitation volumes of 300 ml/kg per 24 h, and percutaneous decompression ...

journal_title：Current opinion in critical care

authors： Namias N

更新日期：2007-08-01 00:00:00

abstract：:Tracheostomy is one of the most common surgical procedures in the intensive care unit. Since the introduction of percutaneous techniques, tracheostomy has become increasingly popular. The technique is relatively easy, and the early and late complication rates are relatively low.It is unknown at which moment tracheosto...

journal_title：Current opinion in critical care

authors： van Heurn LW

更新日期：2000-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Fluid removal and relief of congestion are central to treatment of acute heart failure. Diuretics have been the decongestive mainstay but their known limitations have led to the exploration of alternative strategies. This review compares diuretics with ultrafiltration and examines the recent evidence ...

journal_title：Current opinion in critical care

authors： Krishnamoorthy A,Felker GM

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The mechanisms of epithelial injury in acute lung injury/acute respiratory distress syndrome have been of interest since the syndrome was first described. Cell therapies to replace injured epithelium are a futuristic dream; however, there is ongoing research to achieve this goal. We review research re...

journal_title：Current opinion in critical care

authors： Gropper MA,Wiener-Kronish J

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the progress made over the past 20 years in the treatment of septic shock, mortality remains high. Microcirculatory disorders raise considerable interest aiming to improve the understanding of the physiopathology of septic shock and its management. RECENT FINDINGS:Numerous experimental and cl...

journal_title：Current opinion in critical care

authors： Ait-Oufella H,Bourcier S,Lehoux S,Guidet B

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Although providing palliative care in the ICU has become a priority, the success of different methods to integrate palliative care into the ICU has varied. This review examines the current evidence supporting the different models of palliative care delivery and highlights areas for future study. RECE...

journal_title：Current opinion in critical care

authors： Hua M,Wunsch H

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute respiratory distress syndrome (ARDS) is a multifaceted lung disease with no current effective therapy. Many clinical trials using conventional pharmacologic therapies have failed, suggesting the need to examine alternative approaches. Thus, attention has focused on the therapeutic potential of c...

journal_title：Current opinion in critical care

authors： Maron-Gutierrez T,Laffey JG,Pelosi P,Rocco PR

更新日期：2014-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Ventilator weaning forms an integral part in critical care medicine and strategies to shorten duration are rapidly evolving alongside our knowledge of the relevant physiological processes. The purpose of the current review is to discuss new physiological and clinical insights in ventilator weaning tha...

journal_title：Current opinion in critical care

authors： Haaksma ME,Tuinman PR,Heunks L

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The present article will review the current state of our understanding of nephrotoxic medication-associated acute kidney injury (AKI) and provide strategies to reduce its impact. RECENT FINDINGS:Nephrotoxic medications contribute to a substantial proportion of AKI in hospitalized patients. The previo...

journal_title：Current opinion in critical care

authors： Goldstein SL

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the clear rationale for evidence-based medicine (EvBM) in the challenging realms of resuscitation research, yet also provide case examples in which even the well designed, multicentered randomized clinical trial may have had unrecognized limitations, and thus misleading results. This is whe...

journal_title：Current opinion in critical care

authors： Pepe PE,Aufderheide TP

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Conventional intermittent hemodialysis and continuous veno-venous hemofiltration are the opposite poles of current treatment modalities for patients with acute renal failure in the intensive care unit. Because both intermittent and continuous renal replacement techniques have several disadvantages, al...

journal_title：Current opinion in critical care

authors： Fliser D,Kielstein JT

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Mechanical ventilation is the main supportive therapy for patients with acute respiratory distress syndrome. As with any therapy, mechanical ventilation has side effects and may induce lung injury. This review will focus on stretch-dependent activation of alveolar epithelial and endothelial cells and ...

journal_title：Current opinion in critical care

authors： Lionetti V,Recchia FA,Ranieri VM

更新日期：2005-02-01 00:00:00

abstract：PURPOSE OF REVIEW:End-of-life care and communication deficits are important sources of conflicts within ICU teams and with patients or families. This narrative review describes recent studies on how to improve palliative care and surrogate decision-making in ICUs and compares the results with previously published liter...

journal_title：Current opinion in critical care

authors： Wiedermann CJ,Lehner GF,Joannidis M

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Vascular permeability is traditionally explained by Starling's principle, describing two opposing forces across the endothelial cell line to maintain compartments in balance. Several contradictions to this principle have recently questioned its validity. RECENT FINDINGS:Hydraulic conductivity is kept...

journal_title：Current opinion in critical care

authors： Jacob M,Chappell D

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Efforts to improve outcomes from acute kidney injury (AKI) have focussed on timely diagnosis and effective delivery of basic patient care. Electronic alerts (e-alerts) for AKI have attracted interest as a tool to facilitate this. Initial feasibility has already been demonstrated; this review will disc...

journal_title：Current opinion in critical care

authors： Horne KL,Selby NM

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Postoperative sepsis is a major cause of surgical associated morbidity and mortality. Our goal is to describe its incidence, pathophysiology, and contributing factors. In addition, we will review preventive measures and treatment options that may possibly reduce its healthcare burden. RECENT FINDINGS...

journal_title：Current opinion in critical care

authors： Fried E,Weissman C,Sprung C

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Ventilator-induced lung injury (VILI) can occur despite use of tidal volume (VT) limited to 6 ml/kg of predicted body weight, especially in patients with a smaller aerated compartment (i.e. the baby lung) in which, indeed, tidal ventilation takes place. Because respiratory system static compliance (CR...

journal_title：Current opinion in critical care

authors： Grieco DL,Chen L,Dres M,Brochard L

更新日期：2017-02-01 00:00:00

abstract：PURPOSE OF REVIEW:As incidence of acute lung injury (ALI) increases and case fatality decreases, long-term care of survivors is of public health importance. Previous studies demonstrate that these survivors are at risk for impairment in physical, cognitive and mental health. In this review, we will discuss recent studi...

journal_title：Current opinion in critical care

authors： Hough CL,Herridge MS

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Research and studies related to the long-term consequences of intensive care are increasing. This review focuses on some of the most recent knowledge in this field. RECENT FINDINGS:Still studies regarding the health-related quality of life (HRQOL) in survivors after intensive care are frequently publ...

journal_title：Current opinion in critical care

authors： Flaatten H

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Blunt cerebrovascular injuries (BCVI) are a rare but potentially devastating injury with stroke rates up to 50%. Over the past decade, the recognition and subsequent management of these injuries has undergone a marked evolution. This review will focus on the rationale for BCVI screening, imaging optio...

journal_title：Current opinion in critical care

authors： Burlew CC,Biffl WL

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The scope of this review is to describe what is known about injury outcomes and the principles by which they can be improved by acute phase interventions. Assessing which outcomes matter to trauma patients is important both for the evaluation of existing and novel acute interventions and to assess the...

journal_title：Current opinion in critical care

authors： Brohi K,Cole E,Hoffman K

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Antimicrobials are very commonly used drugs in the intensive care setting. Extensive research has been conducted in recent years to describe their pharmacokinetics/pharmacodynamics in order to maximize the pharmacological benefit and patient outcome. Translating these new findings into clinical practi...

journal_title：Current opinion in critical care

authors： Tsai D,Lipman J,Roberts JA

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to summarize important publications in enhanced recovery during 2010-2011 and to highlight key themes. Specifically, we focus on updated systematic reviews of high-quality clinical trials of enhanced recovery in colorectal surgery, exemplar studies of enhanced recovery in oth...

journal_title：Current opinion in critical care

authors： Grocott MP,Martin DS,Mythen MG

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Part II of this review gives an overview of the different maternal cardiac problems during pregnancy and their management, and developments over recent years. RECENT FINDINGS:Many studies published over the last 5 years provided new insights on different cardiac diseases in pregnancy. Publications di...

journal_title：Current opinion in critical care

authors： van Mook WN,Peeters L

更新日期：2005-10-01 00:00:00