VARIATIONS IN THE ABILITIES OF SEVERAL LINES OF L CELLS TO PRODUCE AND TO BE AFFECTED BY INTERFERON.

Abstract:

:Lockart, Royce Z., Jr. (The University of Texas, Austin). Variations in the abilities of several lines of L cells to produce and to be affected by interferon. J. Bacteriol. 89:117-122. 1965.-The amounts of interferon produced by three different lines of L cells and mouse embryonic cells when inoculated with two strains of Western equine encephalomyelitis (WEE) virus and Newcastle disease virus (NDV) were determined. One cell line consistently produced more interferon than the others. NDV stimulated more interferon than did WEE virus in all the cell lines tested. The interferons failed to show homologous specificity in their ability to inhibit virus production in the three cell lines. The cell line that produced the most interferon also was most sensitive to viral inhibition. This cell line was also most sensitive to the viral inhibitory ability of an interferon prepared in mouse embryonic cells.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

LOCKART RZ Jr

doi

10.1128/JB.89.1.117-122.1965

keywords:

subject

Has Abstract

pub_date

1965-01-01 00:00:00

pages

117-22

eissn

0021-9193

issn

1098-5530

journal_volume

89

pub_type

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