Multianalytic study on cervical HPV lesions.

Abstract:

:Nowadays new sophisticated techniques of molecular biology based on the principles of hybridization between nucleic acids, allow a correct diagnosis of genital HPV infection. In the present paper, beside traditional diagnostic methods, we used In Situ Hybridization (ISH) and Polymerase Chain Reaction (PCR) to detect the presence of HPV types 6, 11, 16, 18, 31 and 33. We tested ten patients affected by cervical lesions of high histological atypias associated with HPV, who underwent surgical conization. Types 6 and 11, at low risk of evolution, are less frequent than 31 and 33, at medium grade of evolution, and than 16 and 18 which are at high risk of evolution.

journal_name

Eur J Gynaecol Oncol

authors

D'Antona N,Tosi P,Ricci MG,Cintorino M,Bernabei A,Leoncini P,Nuti S

keywords:

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

20-4

issue

1 Suppl

eissn

0392-2936

issn

2709-0086

journal_volume

13

pub_type

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