Abstract：
:A prospective, randomized study comparing single dose intravenous antibiotic prophylaxis with multiple-dose regimen in patients undergoing radical surgery for gynecologic malignancy was carried out. The majority of patients had cervical cancer. Thirty-seven patients in group A received one dose of 4 g piperacillin and 800 mg tinidazole 30 minutes before surgery. Twenty-nine patients in group B additionally received 4g piperacillin 8 hours and 4g piperacillin and 800 mg tinidazole 16 hours after the first dose. There were no significant differences between groups A and B with regard to median patient age, performance status, cardiologic and pulmonary status, or frequency of diabetes. There were also no significant differences between either group with regard to the parameters documented postoperatively, such as median hospital stay, leukocyte values, or febrile episodes. Forty-three per cent of patients in group A and 48% of patients in group B had no complications (p > 0.05). Twenty-three per cent of patients in group A and 31% of patients in group B developed infections (p > 0.05), 85% of which occurred in the urinary tract. The data suggest that a single dose of intravenous antibiotics is as effective as multiple dose administration in the perioperative prophylaxis in radical gynecologic surgery.
journal_name
Eur J Gynaecol Oncoljournal_title
European journal of gynaecological oncologyauthors
Mayer HO,Petru E,Haas J,Heydarfadai Msubject
Has Abstractpub_date
1993-01-01 00:00:00pages
177-81issue
3eissn
0392-2936issn
2709-0086journal_volume
14pub_type
临床试验,杂志文章,随机对照试验abstract：:A 33-year-old pregnant woman of 38 weeks' gestation with massive peritoneal ascites presented. A cesarean section was performed and a viable 3.100 g male infant was delivered. Biopsy of the nodular enlargements from the omentum revealed a malignant epithelial peritoneal mesothelioma. Malignant mesothelioma is a rare m...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：PURPOSE OF INVESTIGATION:This study aimed to investigate the immunohistochemical expression of cyclins D1 and E in normal, hyperplastic and neoplastic endometrium, and their correlation with proliferative activity and clinicopathological features. METHODS:We carried out immunohistochemical techniques on archived mater...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Ovarian cancer is not the most frequent malignancy of female reproductive system, but it causes many deaths in women with this diagnosis. Mostly of the patients with ovarian cancer will have recurrence after first-line standard treatment containing surgery and chemotherapy. This article presents two cases with late re...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2015-01-01 00:00:00
abstract：:The concentration of c-erbB-2 oncoprotein (HER-2/neu) was examined in the membrane fraction of 196 breast cancer and 39 benign breast specimens using a recently introduced ELISA-assay. The results were compared with established clinical and laboratory prognostic factors, 19% of all breast cancer specimens showed a c-e...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:In order to find an effective protocol for chemoradiotherapy with mitomycin C (MMC) for advanced cervical cancer patients, effects of both MMC and irradiation on chemoradiosensitivity were examined using the radiosensitive human cervical squamous cell carcinoma cell line ME180. MMC and low doses of irradiation did not...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVE:We aimed to investigate the utility and efficacy of the Keyes skin biopsy instrument for cervical biopsy procedures. MATERIAL AND METHODS:A prospective clinical trial was conducted on 50 women with cervical lesions. Colposcopy-guided cervical biopsies were collected using a Keyes biopsy punch and a Kevorkian...
journal_title：European journal of gynaecological oncology
pub_type： 临床试验,杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To determine the frequency of synchronous primary neoplasia of the ovaries in patients with primary malignant neoplasia of the uterus, and to analyze the clinical and histological characteristics of these cases. MATERIALS AND METHODS:Clinicopathological data from a series of patients treated for primary mali...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:The study population was derived from 482 patients with breast cancer treated at the Department of Oncology, University Hospital Center Zagreb, between 1992 and 1999. The main purpose of our study was to evaluate differences in breast cancer characteristics and treatment in a population of women with breast cancer old...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:Fertility sparing surgery might be a benefit for young patients with early-stage cervical cancer. The authors herein describe a case of adenocarcinoma of cervix Stage IA2 treated with laparoscopic radical trachelectomy (LRT) with round ligament and uterine artery preservation. ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：PURPOSE:Ovarian clear cell adenocarcinoma (OCCA) has been reported to display different characteristics from other histological types of epithelial ovarian cancer, and especially differs from serous adenocarcinoma. We investigated plasminogen activator inhibitor-1 (PAI-1) expression in patients with OCCA and attempted ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：PURPOSE OF INVESTIGATION:To report the differences in ovarian cancer prevalence between the two major ethnic groups (Christian Orthodox and Muslims) in Thrace, Greece. METHOD:We carried out a retrospective study on 57 patients, aged 16-79 years, who were treated in our clinic for ovarian cancer. RESULTS:The cumulativ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:The clinicopathologic features of a patient with primary carcinoid tumor of the ovary who presented with the signs of cardiac failure are described. The patient underwent total abdominal hysterectomy + bilateral salpingo-oophorectomy + omentectomy + bilateral pelvic lymphadenectomy + appendectomy; and she is alive wit...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVE:In order to determine the significance of proliferative activity (PA) in endometrial carcinomas, we analysed the expression of cell cycle-related antigens in routinely processed tissue. MATERIALS AND METHODS:Serial sections of 113 endometrial carcinoma specimens were immunostained with the monoclonal antibod...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：UNLABELLED:OBJECTIVE AND CASE: Both noninvasive and invasive methods have limited value in the diagnosis of metastatic ovarian cancer. We present a case with the initial complaint of abdominal distention in whom primary and metastatic tumor sites were safely diagnosed by using laparoscopy: a gastric tumor with ovarian ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:Correlates of HPV amongst a cohort of women with a CIN I detected by a screening Pap test were investigated. Co-incident CIN II/III lesions were identified and their influence on the HPV status and HPV determinants of screening detected CIN I was assessed. Based on both the colposcopic impression and repeat Pap test, ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:The efficacy of a new device, "the Endopap" endometrial cell sampler in obtaining specimens for cytological examination to detect precursors of malignancy of the endometrium was assessed in 140 asymptomatic and sympomatic women. The cytological results as compared with hystological diagnosis on curettage specimens by ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:From 1985 to 1990, 3040 patients with carcinoma of the uterine cervix were diagnosed and treated at Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. The epidemiological aspects including ages and geographical distributions, histology, stages, treatment and outcome were presented and compared ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:On the basis of a case series of 577 patients affected by carcinoma of the endometrium treated during the period 1963-1989 in the Gynecologic Institute of the Padua University, the present work examines the reliability of endometrial biopsy aiming at the correct histopathologic diagnosis, through comparison with the s...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：PURPOSE OF INVESTIGATION:In this survey we evaluated the prescription attitude of Greek gynecologists towards hormone replacement therapy (HRT) for ovarian cancer survivors. METHODS:An anonymous questionnaire was sent to 900 members of the Hellenic Society of Obstetrics and Gynecology presenting a hypothetical case of...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:The purpose of this retrospective study was to determine the effect of pretreatment surgical staging on survival of patients with locally advanced cervical carcinoma. Two hundred and seventy-four women with cervical cancer stages IIB-IVA treated with primary radiotherapy comprised the study group. Eighty-nine patients...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:In order to determine the clinical significance of numerical aberrations on chromosome 17 in uterine cervical and endometrial neoplasias, we investigated 140 cell specimens obtained from the uterine cervix and endometrium using the fluorescence in situ hybridization (FISH) method. These specimens consisted of ten norm...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:Serum CA 125 levels were measured preoperatively in 126 women subjected to laparotomy due to palpable pelvic mass. Forty out of 42 patients with true malignant serous ovarian carcinoma had serum CA 125 levels higher than 35 U/ml. Among 62 patients with some types of gynecologic malignancy, 48 also met the cutoff value...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Malignant ovarian tumors have been continuously increasing in Western countries and represent the leading cause of death for gynecological cancer. In fact, the mortality for malignant ovarian tumors remains very high with a low percentage of 5-year survival in the advanced stage of disease. The aim of this study was t...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:A primary leiomyosarcoma (LMS) arising from the left fallopian tube in a perimenopausal 48-year-old woman is reported. Primary tubal LMS is an uncommon, exceedingly rare neoplasm, accounting for only a few reported cases so far. To our knowledge, the present case is the 17th tubal LMS reported in the English-language ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:The development of cancer from adenomyotic foci is a rare occurrence. The diagnosis is frequently delayed because of the absence of tumor in the eutopic endometrium. CASE REPORT:We present a case of a 64-year-old postmenopausal woman with irregular vaginal bleeding and dull abdominal pain. Hysteroscopy was ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:Serial serum CA-125 levels were measured in fifteen patients with recurrent or advanced endometrial carcinoma during treatment with chemo- or hormonal therapy. All patients had measurable disease by physical examination, chest X-ray or CT scan. Serum CA-125 levels were invariably elevated, and generally reflected, res...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：AIM:Examination of the potential role of leptin in the development of uterine myomas. Expression of the leptin gene and leptin receptor gene was tested in the myometrium of healthy women, and in myomas and the surrounding myometrium of women with benign tumors. METHODS:Using RT-PCR, expression of the leptin gene and l...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:To evaluate the influence in survival of clinical and pathological findings in patients with endometrial cancer. METHODS:In 152 women treated for endometrial cancer from 1982 to 1996, personal, obstetrical and oncological data, histology, grade, myometrial invasion, peritoneal cytology, FIGO stage and treatmen...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:The Authors present six cases of ovarian neoplasm with histological characteristics of typical Krukenberg tumor. Usually, Krukenberg Tumor is bilateral and often secondary to gastrointestinal carcinomas. Secondary ovarian neoplasms often become evident a short time after the diagnosis of primary tumor. Moreover, the p...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVE:The objective of this study is to describe a new technique of laparoscopic radical hysterectomy without vaginal cuff closure. METHODS:Three patients underwent laparoscopic radical hysterectomy, bilateral salpingo-oophorectomy and bilateral pelvic lymph node dissection using an Argon Beam Coagulator. Four tro...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
