Abstract：
BACKGROUND:The development of cancer from adenomyotic foci is a rare occurrence. The diagnosis is frequently delayed because of the absence of tumor in the eutopic endometrium. CASE REPORT:We present a case of a 64-year-old postmenopausal woman with irregular vaginal bleeding and dull abdominal pain. Hysteroscopy was negative and hormonal treatment was continued. Nine months later, persisting symptoms necessitated endometrial biopsy revealing an atrophic endometrium. Hydrosonography suggested an endometrial polyp of 14 x 7 mm with a surrounding regular thin endometrium and a diffusely inhomogeneous ultrasonographic pattern throughout the myometrium. Hysteroscopic excision of the endometrial polyp was performed. Biopsies obtained during operative hysteroscopy showed a well differentiated endometrioid endometrial carcinoma. A laparoscopically assisted vaginal hysterectomy with bilateral salpingo-oophorectomy, pelvic lymphadenectomy and peritoneal cytology was performed. Pathologic examination revealed an atrophic endometrium and a Stage IB (FIGO 2009) well differentiated endometrioid endometrial carcinoma with prominent squamous differentiation originating from nodular adenomyosis. This ectopic localization of the endometrioid carcinoma added to a diagnostic delay of 12 months. CONCLUSION:Endometrial cancer arising from uterine adenomyosis may be difficult to diagnose. Awareness of this entity and careful ultrasonography are likely to reduce diagnostic delay.
journal_name
Eur J Gynaecol Oncoljournal_title
European journal of gynaecological oncologyauthors
Boes AS,Tousseyn T,Vandenput I,Timmerman D,Vergote I,Moerman P,Amant Fsubject
Has Abstractpub_date
2011-01-01 00:00:00pages
431-4issue
4eissn
0392-2936issn
2709-0086journal_volume
32pub_type
杂志文章abstract：:402 radical hysterectomies (17 ultraradical) were performed with lymphadenectomy. Positive metastatic nodes (N+) rate was 23.6% with an arithmetic mean of 22 excised lymph nodes. Single N+ belonged mostly to the obturatory group, double N+ to obturatory and external iliac groups, while multiple N+ (24 cases) had no pa...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:Cervical cancer should be a historical disease, why are we not succeeding! The prophylactic vaccination will reduce cervical cancer by almost 80% in Belgium. Cervical cancer screening should therefore remain in order to prevent the remaining 20%. The current used Pap cytology test misses 50% of all clinically signific...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2014-01-01 00:00:00
abstract：:We report seven cases of intravenous leiomyomatosis. Growth beyond the uterus occurred in two of the seven cases in the broad ligament. One 21-year-old patient is one of the youngest reported cases in the literature. Five patients had total abdominal hysterectomy with removal of the adnexa and two patients underwent m...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:A combined modality therapy (irradiation plus low-dose Adriamycin and Cyclophosphamide) was delivered to 41 patient affected by extensive bone diffusion from breast carcinoma. A 36% (15/41) objective response rate was obtained, no change was also detectable in 36%, while progressive disease in 28% (11/41). A subjectiv...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：PURPOSE:To determine the safety of omitting routine interval laboratory assessments, dietary restrictions, and isolation precautions between cycles of chemotherapy for gynecologic malignancies. METHODS:Data were retrospectively obtained from the records of women receiving chemotherapy for gynecologic cancer from July ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:Synchronous endometrioid carcinoma of the uterine corpus and ovary is an uncommon but well recognized event. Diagnosis as either a separate independent primary or as a metastatic tumor requires careful consideration of a number of gross and histological features. These features illustrate the criteria helpful in disti...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2009-01-01 00:00:00
abstract：:The usefulness of urine cyclic guanosine 3'-5'monophosphate (GMP (cGMP) as a cancer marker in ovarian cancer has been studied in two independent centres using specimens from 81 women. Serial specimens from 60 patients were monitored up to 2 years after the start of chemotherapy. Urine cGMP levels were significantly hi...
journal_title：European journal of gynaecological oncology
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1990-01-01 00:00:00
abstract：:Ovarian mucinous tumors stem from ovarian surface epithelium and are divided into benign, borderline and malignant. It is difficult to differentiate borderline and malignant mucinous tumors. Thirty-eight cases of ovarian mucinous tumors which were diagnosed at the Pathology Department of Dicle University Medical Facul...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:Granulosa cell tumors (GCT) constitute 70% of all ovarian sex-cord stromal tumors, which account for less than five percent of all ovarian carcinoma. The authors herein report a rare case of a ruptured GCT of the ovary in a 43-year-old female who was admitted to the emergency department with signs of acute abdomen. ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:By interview with several women a dramatic problem for the doctors: how to give doomed patients something more than mere medical help. ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:Secondary healing of complicated vulvar and groin wounds is a major challenge due to its moist condition and at risk of contamination by colonic flora. Vacuum assisted closure is the controlled application of sub-atmospheric pressure to the local wound environment using a sealed dressing connected to a vacuum pump. M...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：PURPOSE OF INVESTIGATION:1) To assess whether endometrial specimens obtained from removed uteri might show an increase in endometrial pathologies which had been previously diagnosed by hysteroscopy in postmenopausal breast cancer tamoxifen-treated patients. 2) To assess whether hysteroscopy is an efficient method of de...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:This study aims to investigate the correlation and clinical significance of hormone receptors and the expressions of HER-2 and Ki-67 in breast cancer primary lesions and lymph node metastatic tissues. METHODS:83 cases were studied, who were performed breast cancer surgeries and confirmed the ipsilateral axil...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2015-01-01 00:00:00
abstract：PURPOSE:Differences of the clinical features of Stage I borderline ovarian tumors and Stage I ovarian cancer need to be clarified. METHODS:We retrospectively investigated 215 patients with Stage I ovarian tumors (67 with borderline tumors and 148 with ovarian cancer) treated between 1988 and 2001. RESULTS:Only one pa...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：INTRODUCTION:Genotyping of UGTI1Al could be useful for prediction of severe toxicities for patients treated with irinotecan; however, genotype-based recommended dose (RD) has not been established. The aim of the present study was to determine the RD of irinotecan in combination with cisplatin (CPT-P) for individuals wi...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:Complications of 140 cases of squamous carcinoma of the cervix treated by surgery are analyzed. Intra- and post-operative morbidity is considered; intra-operative morbidity was very low. Post-operative morbidity was mainly rappresented by early and late bladder dysfunction. Recurrence rate is analyzed; it is 10%. ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND:Soft tissue sarcomas are rare and account for less than 1% of all newly diagnosed malignancies. One-third of malignant tumors arising in the retroperitoneum are sarcomas. Liposarcoma is the most common soft tissue sarcoma and retroperitoneal sarcoma. Liposarcoma accounts for at least 20% of all sarcomas in a...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2012-01-01 00:00:00
abstract：:Aggressive fibromatoses (desmoid tumors) are rare tumors of fibroblastic origin that may arise in any musculoaponeurotic structure with a propensity of infiltrate adjacent tissues, but not to metastasize. Tumors of musculoaponeurotic origin are seldom encountered by the gynecologist. A case of pelvic fibromatosis is r...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The preceding platinum-based combination chemotherapy could possibly reduce tumor masses, allowing for adequate surgical debulking in advanced ovarian cancer. In this study, a total of 18 patients with peritoneal carcinomatosis of the ovary were evaluated between 1996 and 2003. All patients underwent open biopsy for t...
journal_title：European journal of gynaecological oncology
pub_type： 临床试验,杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:Neoadjuvant chemotherapy in gynecological cancers is an approach that is shown to have positive effects on survival. It increases the rate of resectability in ovarian and cervical cancers and thus contributes to survival. However, there are studies reporting that despite increasing operability, the approach does not m...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVE:We aimed to evaluate the knowledge and interest level of Turkish women about HPV, HPV vaccines and cervical cancer using a questionaire. METHOD:A 25-item questionnaire was distributed to women in three different cities located in separate sociocultural locations. RESULTS:At the closure of the study 143 wome...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：PURPOSE OF INVESTIGATION:To compare the therapeutic and side effects of using Californium252 (252Cf) neutron brachytherapy with neoadjuvant intra-arterial embolism chemotherapy in combination with surgery for treating Stage Ib2-IIb cervical cancers (CCs). MATERIALS AND METHODS:Thirty-two Stage Ib2-IIb CC patients were...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2015-01-01 00:00:00
abstract：:Serial serum CA-125 levels were measured in fifteen patients with recurrent or advanced endometrial carcinoma during treatment with chemo- or hormonal therapy. All patients had measurable disease by physical examination, chest X-ray or CT scan. Serum CA-125 levels were invariably elevated, and generally reflected, res...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to assess the efficacy and side-effects of abdominopelvic irradiation applied as adjuvant postoperative therapy in early stage ovarian carcinomas. METHODS:From 1 January 1988 to 31 December 1993, 113 patients with FIGO stage IA-IIC epithelial ovarian carcinoma were treated with ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVE:To determine whether there is a node count which can define an adequate inguinofemoral lymphadenectomy (IFL) in primary VSCC. METHODS:A retrospective and prospective review of patients with node negative VSCC who had a full staging IFL. Detection of isolated groin recurrences (IGR) would allow groins with hi...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:Primary ovarian carcinosarcoma is characterized by an admixture of malignant epithelial and stromal elements. This neoplasm is extremely rare with fewer than 400 cases reported in the English literature. Its histogenesis, clinical features and optimal treatment remain unclear because of the rarity of primary ovarian c...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVE:To report the first case of a uterine gestational choriocarcinoma coexisting with an endometrial carcinoma (EC) and to discuss its possible pathogenesis. MATERIALS AND METHODS:All tissues were examined histologically and monoclonal antibodies were used to evaluate the expression of HCG, HPL, P53, PTEN, and E...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:Serum CA 125 levels were measured preoperatively in 126 women subjected to laparotomy due to palpable pelvic mass. Forty out of 42 patients with true malignant serous ovarian carcinoma had serum CA 125 levels higher than 35 U/ml. Among 62 patients with some types of gynecologic malignancy, 48 also met the cutoff value...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVE:The objective of this work was to assess proper management of squamous intraepithelial lesion (SIL) and microinvasive carcinoma during and after pregnancy, to assess risks of punch biopsy and conization in pregnancy and to assess regression, persistence and risk of progression with low-grade (L) and high-grad...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：INTRODUCTION:Malignant mixed mullerian tumor (MMMT) of the ovary is an extremely rare gynaecologic neoplasm that represents 1% of the malignances of this organ. Stage I disease is rare because it is asymptomatic in early stage. We describe four cases. CASE REPORTS:In the Department of Obstetrics and Gynecology of the ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
