Helping adolescents cope with stress during stressful times.

abstract：PURPOSE OF REVIEW:22q11 deletion syndrome is the most common genetic abnormality. More patients are surviving cardiac surgery, and many do not have cardiac anomalies. Adult patients are now being described. It is important for paediatricians, and increasingly adult physicians, to be aware of the optimum management of t...

journal_title：Current opinion in pediatrics

authors： Gennery AR

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Altered epigenetics is central to oncogenesis in many pediatric cancers. Aberrant epigenetic states are induced by mutations in histones or epigenetic regulatory genes, aberrant expression of genes regulating chromatin complexes, altered DNA methylation patterns, or dysregulated expression of noncodin...

journal_title：Current opinion in pediatrics

authors： Panditharatna E,Filbin MG

更新日期：2020-02-01 00:00:00

abstract：:Herbal medicaments are in common use. In general, the judicious use of carefully selected and prepared herbal medications seems to cause few adverse effects and may be beneficial. However, toxic effects of these products have been reported with increasing frequency. Infants and children may be even more susceptible to...

journal_title：Current opinion in pediatrics

authors： Tomassoni AJ,Simone K

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines neonatal bacterial skin infections with respect to host immunity, bacterial pathogens, patterns of infection, and new therapeutic approaches. RECENT FINDINGS:Advances have been made in our understanding of innate host defense and the emerging role of cutaneous antimicrobial pepti...

journal_title：Current opinion in pediatrics

authors： Larson AA,Dinulos JG

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Concern regarding appendicitis is a common reason for presentation to the paediatric emergency department. We review recent progress in the use of biomarkers, imaging and clinical scoring systems in improving diagnostic accuracy in suspected appendicitis in children. RECENT FINDINGS:Use of ultrasound...

journal_title：Current opinion in pediatrics

authors： Lawton B,Goldstein H,Davis T,Tagg A

更新日期：2019-06-01 00:00:00

abstract：:Pediatric cardiac intensive care has emerged as a distinct clinical entity to meet the unique needs of pediatric patients with congenital and acquired heart disease. This new subspecialty demands expertise and experience in the pediatric subspecialties of cardiology, intensive care, cardiac surgery, cardiac anesthesia...

journal_title：Current opinion in pediatrics

authors： Chang AC

更新日期：2000-06-01 00:00:00

abstract：:The insulin-like growht factors (IGFs) are potent mitogenic agents that have been recognized for three decades. Recently, however, the complex milieu in which they operate has begun to be unraveled. Endocrine and autocrine patterns of IGF secretion have been identified and specific receptors that bind IGFs and mediate...

journal_title：Current opinion in pediatrics

authors： Cohen P,Rosenfeld RG

更新日期：1994-08-01 00:00:00

abstract：:Atopic dermatitis is the most common chronic skin disease of young children and is frequently associated with asthma and allergies. Th2-type cytokine secreting T cells expressing the cutaneous lymphocyte-associated antigen play a central role in the induction of local IgE responses and recruitment of eosinophils in th...

journal_title：Current opinion in pediatrics

authors： Boguniewicz M

更新日期：1997-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Major advances in our understanding of the genetic basis of neuroblastoma, and the role somatic alterations play in driving tumor growth, have led to improvements in risk-stratified therapy and have provided the rationale for targeted therapies. In this review, we highlight current risk-based treatmen...

journal_title：Current opinion in pediatrics

authors： Bagatell R,Cohn SL

更新日期：2016-02-01 00:00:00

abstract：:Attention-deficit hyperactivity disorder has been redefined in the classifications in the International Classification of Disease, 10th revision and Diagnostic and Statistical Manual of Mental Disorders, fourth edition. The definitions are more concordant than their predecessors and reemphasize the distinction between...

journal_title：Current opinion in pediatrics

authors： Baxter PS

更新日期：1995-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Developmental speech and language disorders are common, seen in one in 20 preschool children, in the absence of frank neurological deficits or intellectual impairment. They are a key reason parents seek help from paediatricians. Complex neurogenetic and environmental contributions underpin the disorde...

journal_title：Current opinion in pediatrics

authors： Morgan A,Bonthrone A,Liégeois FJ

更新日期：2016-12-01 00:00:00

abstract：:Miniaturization of echocardiographic transducers, improved crystal technology, and enhanced digital processing of ultrasound signals have resulted in newer, more sophisticated equipment and imaging techniques. These technologic advances include transesophageal echocardiography, stress echocardiography (both pharmacolo...

journal_title：Current opinion in pediatrics

authors： Marx GR

更新日期：1995-10-01 00:00:00

abstract：PURPOSE OF REVIEW:For the past 20 years, sonography of the hip has become the imaging procedure of choice to diagnose hip maturation disorders in German-speaking countries. In Austria, hip sonography is a mandatory and essential feature of preventive public health measures; the "Mutter-Kind-Pass" has been the official ...

journal_title：Current opinion in pediatrics

authors： Dorn U,Neumann D

更新日期：2005-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Adolescents, in particular those that are most disenfranchised, are increasingly at risk of acquiring HIV and, when acquiring HIV, have worse outcomes than adults. This article reviews the recent approaches to combination prevention aiming to optimize the HIV prevention and HIV treatment continua. RE...

journal_title：Current opinion in pediatrics

authors： Rotheram-Borus MJ,Davis E,Rezai R

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Owing to its aggressive clinical course and associated immunologic abnormalities, pediatric inflammatory bowel disease (IBD) is increasingly managed with immunomodulators and biologic agents. Clinical experience with therapy targeted against tumor necrosis factor-alpha has raised important questions a...

journal_title：Current opinion in pediatrics

authors： Rosh JR

更新日期：2009-10-01 00:00:00

abstract：:Inhalants remain one of the most commonly abused substances by adolescents in the United States today. Recent epidemiologic studies have demonstrated a decrease in the prevalence of inhalant abuse, but overall rates remain high. Inhalants have the potential to result in serious organ system dysfunction or even sudden ...

journal_title：Current opinion in pediatrics

authors： Lorenc JD

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Neonates are at a high risk of infection and may have nonspecific signs of sepsis. Accordingly, they are heavily exposed to antimicrobials. Neonates are also uniquely at risk of both short-term and long-term complications from antibiotic exposure. This review discusses advances in antibiotic stewardsh...

journal_title：Current opinion in pediatrics

authors： Willis Z,de St Maurice A

更新日期：2019-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Osteogenic sarcoma, also known as osteosarcoma, is a primary malignancy of the bone in which spindle cells produce osteoid. Although rare in the general population, these tumors are the most common primary malignancies of bone and the fifth most common primary malignancy of adolescence. This paper aim...

journal_title：Current opinion in pediatrics

authors： Kim HJ,Chalmers PN,Morris CD

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:First-time parents often turn to friends and family for advice regarding feeding, sleeping, bathing, diapering and toilet training, and childhood illnesses. Unfortunately, parents may at times be given incorrect and potentially dangerous advice as several widely embraced parenting practices are no lon...

journal_title：Current opinion in pediatrics

authors： Kahan T,Adesman A

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will focus on therapeutic considerations and recent advances in treatment of caustic ingestion injuries. RECENT FINDINGS:A retrospective study suggests that it may be safe to advance the endoscope beyond the first circumferential burn to allow for a more complete assessment of extent of i...

journal_title：Current opinion in pediatrics

authors： Shub MD

更新日期：2015-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Tobacco use and secondhand tobacco smoke exposure of children are a significant problem faced by pediatricians. This article reviews the recommendations of the 2008 update of the guideline Treating Tobacco Use and Dependence and their application in the pediatric setting. RECENT FINDINGS:Every tobacc...

journal_title：Current opinion in pediatrics

authors： Caponnetto P,Polosa R,Best D

更新日期：2008-12-01 00:00:00

abstract：:The biology of the X chromosome is unique, as there are two Xs in females and only a single X in males, whereas the autosomes are present in duplicate in both sexes. The presence of only a single autosome, which can occur as a result of an error in meiotic segregation, is invariably an embryonic lethal event. Monosomy...

journal_title：Current opinion in pediatrics

authors： Gartler SM,Goldman MA

更新日期：2001-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent progress in our understanding of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) and IPEX-related disorders. RECENT FINDINGS:A number of Mendelian disorders of immune dysregulation and autoimmunity have been noted to result from defects in T regulatory cell,...

journal_title：Current opinion in pediatrics

authors： Verbsky JW,Chatila TA

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In fiscally challenging times, scientists must seek creative strategies and leverage existing resources to advance research. RECENT FINDINGS:This review describes programmes supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) to promote resear...

journal_title：Current opinion in pediatrics

authors： Burns KM,Pearson GD,Kaltman JR

更新日期：2013-10-01 00:00:00

abstract：:A careful history and physical examination will help to differentiate between encopresis with or without constipation and fecal incontinence caused by anatomic or organic disease. Most children with encopresis with or without functional constipation require no or minimal laboratory workup. Successful treatment of enco...

journal_title：Current opinion in pediatrics

authors： Loening-Baucke V

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To review recent advances in severe congenital neutropenia (SCN) syndromes. RECENT FINDINGS:The majority of patients with SCN bear monoallelic mutations in the neutrophil elastase (ELANE) gene. Biallelic mutations in the antiapoptotic gene HAX1 were identified in patients with autosomal recessive SCN...

journal_title：Current opinion in pediatrics

authors： Boztug K,Klein C

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To familiarize primary care pediatricians with basic detection and treatment strategies of lower extremity stress fractures, while highlighting new research related to improving diagnosis and management approaches for pediatric and adolescent athletes. RECENT FINDINGS:Young age appears to be a risk f...

journal_title：Current opinion in pediatrics

authors： Heyworth BE,Green DW

更新日期：2008-02-01 00:00:00

abstract：:Thrombopoietin is a hematopoietic growth factor that stimulates megakaryopoiesis. Recent results indicate that thrombopoietin has multilineage hematopoietic effects both in vitro and in vivo. Clinical studies of thrombopoietin have begun, and are reviewed. ...

journal_title：Current opinion in pediatrics

authors： Broudy VC,Kaushansky K

更新日期：1998-02-01 00:00:00

abstract：:Bone marrow transplantation has become well established in the treatment of malignant and nonmalignant disorders. Steady progress continues in improving survival after transplantation, but many problems remain to be solved. Relapsed disease is a major limitation, and new, more intensive preparative regimens are being ...

journal_title：Current opinion in pediatrics

authors： Robertson KA

更新日期：1993-02-01 00:00:00

abstract：:In 1995, the incidence of childhood thyroid cancer in England and Wales was only 0.5 cases per million children per year. Papillary cancers in younger children were histologically distinct from tumors in older individuals. The incidence of thyroid cancer in the vicinity of Chernobyl increased by 62 times within 5 year...

journal_title：Current opinion in pediatrics

authors： Zimmerman D

更新日期：1997-08-01 00:00:00