Nalpha-methylhistamine safety and efficacy in migraine prophylaxis: phase I and phase II studies.

abstract：BACKGROUND:The buildup time of migraine headaches has not been well delineated in publications to date and we are aware of patients whose migraines last well over 72 hours. More concentration on these factors in the assessment of patients might lead to more appropriate therapeutic choices. METHOD:Prospective ascertain...

journal_title：Headache

authors： Pryse-Phillips W,Aubé M,Bailey P,Becker WJ,Bellavance A,Gawel M,Giammarco R,Mackie G,Purdy RA,Robinson G,Shapero G,Wilson K

更新日期：2006-11-01 00:00:00

abstract：:Several second-generation triptans have been introduced that differ in their pharmacologic profiles relative to each other and to sumatriptan. As therapeutic options multiply, clinicians must be able to distinguish among these compounds. Recently, a meta-analysis was conducted on data from 53 double-blind, randomized,...

journal_title：Headache

authors： Ferrari MD

更新日期：2002-01-01 00:00:00

abstract：:Clinical and pathophysiological evidences connect migraine and the cerebellum. Literature on documented cerebellar abnormalities in migraine, however, is relatively sparse. Cerebellar involvement may be observed in 4 types of migraines: in the widespread migraine with aura (MWA) and migraine without aura (MWoA) forms;...

journal_title：Headache

authors： Vincent M,Hadjikhani N

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:To assess the acute treatment of pregnant women presenting to a hospital with migraine. BACKGROUND:Migraine is a common problem in pregnancy; however, migraine treatment is challenging in pregnant women for fears of medication teratogenicity and lack of data in this population. To date, no study has directly...

journal_title：Headache

authors： Hamilton KT,Robbins MS

更新日期：2019-02-01 00:00:00

abstract：:The aim of the study was to compare adult migraine discordant full siblings in terms of personality and psychosocial environment during childhood. The study, involving 30 sibling pairs and use of various personality instruments (Eysenck Personality Inventory [EPI], Color Word Test [CWT], Visual Aftereffects [VAE], Met...

journal_title：Headache

authors： Persson B

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Medication-overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the shifting from drug use to drug abuse. The main aim of this study is to study personality, according to Minnesota Multiphasic Personality Inventory, compa...

journal_title：Headache

authors： Galli F,Pozzi G,Frustaci A,Allena M,Anastasi S,Chirumbolo A,Ghiotto N,Guidetti V,Matarrese A,Nappi G,Pazzi S,Quartesan R,Sances G,Tassorelli C

更新日期：2011-09-01 00:00:00

abstract：:Hemicrania continua (HC) is a primary chronic headache disorder, characterized by a continuous and strictly unilateral headache, with possible cranial autonomic symptoms during episodes of pain exacerbation. The unilateral headache generally responds well to indomethacin; however, continuous indomethacin intake is oft...

journal_title：Headache

authors： Eren O,Straube A,Schöberl F,Schankin C

更新日期：2017-02-01 00:00:00

abstract：:This work assesses the differences in the thermographic findings in the craniofacial and neck areas between normal individuals and patients with craniofacial pain or headache, and investigates the influence of muscle contraction on such findings. Thermographic records were taken in 10 healthy subjects and 47 patients ...

journal_title：Headache

authors： Mongini F,Caselli C,Macrì V,Tetti C

更新日期：1990-07-01 00:00:00

abstract：:Eighty-eight children and adolescents were prospectively evaluated at eight specialty clinics comparing the diagnostic criteria of the International Headache Society (IHS) and the proposed revised (IHS-R) classification to the clinical diagnosis. The proposed revisions to the IHS classification for pediatric migraine ...

journal_title：Headache

authors： Winner P,Wasiewski W,Gladstein J,Linder S

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Headache diaries are a mainstay of migraine management. While many commercial smartphone applications (apps) have been developed for people with migraine, little is known about how well these apps protect patient information and whether they are secure to use. OBJECTIVE:We sought to assess whether there are...

journal_title：Headache

authors： Minen MT,Stieglitz EJ,Sciortino R,Torous J

更新日期：2018-07-01 00:00:00

abstract：:A retrospective study was conducted on 1300 women suffering from migraine without aura referred to the Headache Centers of Parma and Pavia from 1984 to 1990. All the data concerning their reproductive life, and the modifications induced by it on the course of headache were obtained from record-charts. Migraine frequen...

journal_title：Headache

authors： Granella F,Sances G,Zanferrari C,Costa A,Martignoni E,Manzoni GC

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVES:To report the case of a patient enduring migraine attacks preceded by hallucinatory olfactory symptoms, with characteristics which typically define migraine with aura (MWA). BACKGROUND:MWA accounts for about 30-40% of the total cases of migraine and is almost always preceded by visual disorders; and in rare...

journal_title：Headache

authors： Tiriticco M,Vanotti A,Mantica D,Coppola A

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To compare, using a within-woman analysis, the severity, duration, and relapse of menstrual vs nonmenstrual episodes of migraine during treatment with usual migraine therapy. BACKGROUND:Studies comparing the clinical characteristics of menstrual and nonmenstrual migraine attacks have yielded conflicting resu...

journal_title：Headache

authors： MacGregor EA,Victor TW,Hu X,Xiang Q,Puenpatom RA,Chen W,Campbell JC

更新日期：2010-04-01 00:00:00

abstract：:We report the case of a man with episodic cluster headache who suffered from severe obstructive sleep apnea (OSA) as well as periodic limb movements during sleep (PLMS). His attacks of headache occurred primarily during sleep being timely to REM sleep as 90 to 120 minutes interval. OSAs were more frequent and prolonge...

journal_title：Headache

authors： Pelin Z,Bozluolcay M

更新日期：2005-01-01 00:00:00

abstract：:This study examined the relationship between the menstrual cycle, the stress process, and migraines. Women migraineurs (N = 12) and a matched control sample (N = 12) completed a set of questionnaires assessing stress, appraisal, and coping at premenses, menses, and ovulation. In addition, migraineurs completed a month...

journal_title：Headache

authors： Holm JE,Bury L,Suda KT

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:To describe a standardized methodology for the performance of peripheral nerve blocks (PNBs) in the treatment of headache disorders. BACKGROUND:PNBs have long been employed in the management of headache disorders, but a wide variety of techniques are utilized in literature reports and clinical practice. MET...

journal_title：Headache

authors： Blumenfeld A,Ashkenazi A,Napchan U,Bender SD,Klein BC,Berliner R,Ailani J,Schim J,Friedman DI,Charleston L 4th,Young WB,Robertson CE,Dodick DW,Silberstein SD,Robbins MS

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To establish if criteria for the diagnosis of migraine change with age and to document the influence of age on the full spectrum of migraine features. Also to define the clinical spectrum and provide a prognostic profile of migraine stratified by age. BACKGROUND:Few studies have formally analyzed migraine ch...

journal_title：Headache

authors： Kelman L

更新日期：2006-07-01 00:00:00

abstract：:Botulinum toxin type A, a protein long used in the successful treatment of various dystonias, has a complex mechanism of action that results in muscle relaxation. At the neuromuscular junction, the presynaptic nerve ending is packed with synaptic vesicles filled with acetylcholine, and clustered at the tip of the fold...

journal_title：Headache

authors： Dolly O

更新日期：2003-07-01 00:00:00

abstract：:In a data base of 1013 patients with chronic headache, 44.1% reported the onset of headaches before the age of 20 (preadult-onset headache) and 55.9% at or after that age (adult-onset headache). Circumstances of headache onset were mentioned significantly more frequently in the latter than in the former group (8.5% ve...

journal_title：Headache

authors： Karpouzis KM,Spierings EL

更新日期：1999-05-01 00:00:00

abstract：:We studied 11 patients undergoing a routine lumbar puncture to determine if there were cerebrospinal fluid leaks at the puncture site and whether the maximum volume of leakage correlates with a lumbar puncture headache. Patients completed a headache questionnaire before and after the lumbar puncture. Limited magnetic ...

journal_title：Headache

authors： Iqbal J,Davis LE,Orrison WW Jr

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine chronic brain white matter hyperintensities in migraine and to gain data on the characteristics of the lesions. BACKGROUND:Migraine associates with a higher incidence of magnetic resonance imaging (MRI)-visible white matter signal abnormalities. Several attack-related pat...

journal_title：Headache

authors： Aradi M,Schwarcz A,Perlaki G,Orsi G,Kovács N,Trauninger A,Kamson DO,Erdélyi-Bótor S,Nagy F,Nagy SA,Dóczi T,Komoly S,Pfund Z

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:It has been suggested that homocysteine (Hcy) and the 5'-10'-methylenetetrahydrofolate reductase (MTHFR) C677T variant are implicated in the pathogenesis of migraine. Homocysteine has the potential to damage endothelium and accelerate atherosclerosis. Genetic factors such as the MTHFR C677T polymorphism, and...

journal_title：Headache

authors： Oterino A,Toriello M,Valle N,Castillo J,Alonso-Arranz A,Bravo Y,Ruiz-Alegria C,Quintela E,Pascual J

更新日期：2010-01-01 00:00:00

abstract：:Brain magnesium was measured in migraine patients and control subjects using in vivo 31-Phosphorus Nuclear Magnetic Resonance Spectroscopy. pMg and pH were calculated from the chemical shifts between Pi, PCr and ATP signals. Magnesium levels were low during a migraine attack without changes in pH. We hypothesize that ...

journal_title：Headache

authors： Ramadan NM,Halvorson H,Vande-Linde A,Levine SR,Helpern JA,Welch KM

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Several studies suggest an association between migraine and juvenile stroke. Because of some shortcomings, we designed another case-control study of a homogenous group of patients with juvenile cerebral ischemia. This study is part of a larger German epidemiological research project on the association of mig...

journal_title：Headache

authors： Schwaag S,Nabavi DG,Frese A,Husstedt IW,Evers S

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVES:To examine the relationship between migraine and nonmigrainous headache and asthma, hay fever, and chronic bronchitis in a large cross-sectional population-based study. BACKGROUND:Associations between prevalence of migraine and asthma or allergy have been demonstrated in clinic-based and epidemiologic studi...

journal_title：Headache

authors： Aamodt AH,Stovner LJ,Langhammer A,Hagen K,Zwart JA

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:This study describes the pain characteristics of the acute migraine attack, including time of onset, time to peak, duration, intensity, quality, aggravation by activity, as well as recurrence frequency and time to recurrence, in a tertiary care practice. BACKGROUND:The literature documenting the characteris...

journal_title：Headache

authors： Kelman L

更新日期：2006-06-01 00:00:00

abstract：:We present a patient with treatment refractory short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) who was found to have low levels of serum testosterone supporting the hypothalamic connection to this trigeminal autonomic cephalalgia. Clomiphene citrate therapy induce...

journal_title：Headache

authors： Rozen TD,Saper JR,Sheftell FD,Dodick DW

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:It is commonly known that headaches are induced by intake of specific food, drink, and/or additive. In addition, some patients experience postprandial headache independent of ingestion of specific items. Currently, information on the pathophysiology underlying this particular type of headache is scarce. CAS...

journal_title：Headache

authors： Takizawa T,Shibata M,Hiraide T,Seki M,Takahashi S,Suzuki N

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of early acute migraine intervention with almotriptan vs placebo on functional disability and health-related quality of life (HRQoL) indicators. DESIGN/METHODS:In this multicenter, double-blind, parallel-group trial, adults with international classification of headache disorders-def...

journal_title：Headache

authors： Freitag F,Smith T,Mathew N,Rupnow M,Greenberg S,Mao L,Finlayson G,Wright P,Biondi D,AEGIS Investigator Study Group.

更新日期：2008-03-01 00:00:00

abstract：:A 57-year-old woman presented with an escalation of her headaches which ultimately progressed to multiple strokes and death. MRI/MRA demonstrated diffuse vasospasm and other causes of stroke were excluded on premortem investigation and postmortem examination. Reversible MRI abnormalities, vasospasm on angiogram and fa...

journal_title：Headache

authors： Marshall N,Maclaurin WA,Koulouris G

更新日期：2007-02-01 00:00:00