Abstract:
:Using a modified version of a phenomenological model for the dynamics of synaptic plasticity, we examine some recent experiments of Wu et al. [(2001) J Physiol 533:745-755]. We show that the model is quantitatively consistent with their experimental protocols producing long-term potentiation (LTP) and long-term depression (LTD) in slice preparations of rat hippocampus. We also predict the outcome of similar experiments using different frequencies and depolarization levels than reported in their results.
journal_name
Biol Cybernjournal_title
Biological cyberneticsauthors
Whitehead A,Rabinovich MI,Huerta R,Zhigulin VP,Abarbanel HDdoi
10.1007/s00422-002-0376-4keywords:
subject
Has Abstractpub_date
2003-03-01 00:00:00pages
229-35issue
3eissn
0340-1200issn
1432-0770journal_volume
88pub_type
杂志文章abstract::Arthropods as well as mammals are able to return straight home after a random search excursion under conditions that are designed to exclude all external cues. After a brief clarification of the terminology, two principal systems of information processing that can achieve this performance are introduced and analysed: ...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s004220000169
更新日期:2000-09-01 00:00:00
abstract::The trace version of classical conditioning is used as a prototypical hippocampal-dependent task to study the recoding sequence prediction theory of hippocampal function. This theory conjectures that the hippocampus is a random recoder of sequences and that, once formed, the neuronal codes are suitable for prediction....
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-005-0568-9
更新日期:2005-06-01 00:00:00
abstract::A theoretical and experimental study on the detection of a square wave pattern of random dots is presented. Our theory applies to two-alternative forced choice experiments as well as to "seen"-"not seen" discrimination experiments. In our experiments we used the forced choice method. The theory provides a good descrip...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00318084
更新日期:1983-01-01 00:00:00
abstract::Small inhibitory neuronal circuits have long been identified as key neuronal motifs to generate and modulate the coexisting rhythms of various motor functions. Our paper highlights the role of a cellular switching mechanism to orchestrate such circuits. The cellular switch makes the circuits reconfigurable, robust, ad...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-018-0778-6
更新日期:2019-04-01 00:00:00
abstract::It is generally held that the right and left middle ears of mammals are acoustically isolated from each other, such that mammals must rely on neural computation to derive sound localisation cues. There are, however, some unusual species in which the middle ear cavities intercommunicate, in which case each ear might be...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-015-0675-1
更新日期:2016-10-01 00:00:00
abstract::The present paper considers the relation between the shape of a triangle and probability of its recognition. An effect of triangle size on perception of its shape is examined in the first experiment. In the second the loci of eye fixations during triangle recognition task are recorded and analysed. A simulation model ...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00363955
更新日期:1988-01-01 00:00:00
abstract::The proposal that rod outer segment length is optimal with respect to photon absorption and noise control is extended and tested in a number of species. We find good agreement with our optimality criterion in duplex retinae where rods act as detectors of one or a few photons, but not in all rod retinae nor in those wh...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00203666
更新日期:1992-01-01 00:00:00
abstract::With regular trains of stimuli at a high frequency, the contribution of each stimulus to the force generated over time declines from the second to about the tenth stimulus, but then begins to increase again. This late increase is referred to as tetanic potentiation in analogy with the post-tetanic potentiation of the ...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00340074
更新日期:1982-01-01 00:00:00
abstract::The notion that biological systems come to embody optimal solutions seems consistent with the competitive drive of evolution. It has been used to interpret many examples of sensorimotor behavior. It is attractive from the viewpoint of control engineers because it solves the redundancy problem by identifying the one op...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-012-0514-6
更新日期:2012-12-01 00:00:00
abstract::The problem of estimating an unknown transient signal, given an ensemble of waveforms, in which this signal appears as a nonrandom component in the presence of additive noise is considered. This problem is solved by generalizing the method of "a posteriori 'Wiener' filtering". In the new method, the ensemble average i...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00340323
更新日期:1981-01-01 00:00:00
abstract::This paper deals with the problem of representing and generating unconstrained aiming movements of a limb by means of a neural network architecture. The network produced time trajectories of a limb from a starting posture toward targets specified by sensory stimuli. Thus the network performed a sensory-motor transform...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF02414903
更新日期:1989-01-01 00:00:00
abstract::Neurons receive a continual stream of excitatory and inhibitory synaptic inputs. A conductance-based neuron model is used to investigate how the balanced component of this input modulates the amplitude of neuronal responses. The output spiking rate is well described by a formula involving three parameters: the mean mu...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-003-0408-8
更新日期:2003-08-01 00:00:00
abstract::In internally coupled ears (ICE), the displacement of one eardrum creates pressure waves that propagate through air-filled passages in the skull, causing a displacement of the opposing eardrum and vice versa. In this review, a thorough mathematical analysis of the membranes, passages, and propagating pressure waves re...
journal_title:Biological cybernetics
pub_type: 杂志文章,评审
doi:10.1007/s00422-016-0696-4
更新日期:2016-10-01 00:00:00
abstract::In this paper, we present a continuous attractor network model that we hypothesize will give some suggestion of the mechanisms underlying several neural processes such as velocity tuning to visual stimulus, sensory discrimination, sensorimotor transformations, motor control, motor imagery, and imitation. All of these ...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-006-0131-3
更新日期:2006-12-01 00:00:00
abstract::This paper proposes multiport parallel and multidirectional intraconnected associative memories of outer product type with reduced interconnections. Some new reduced order memory architectures such as k-directional and k-port parallel memories are suggested. These architectures are, also, very suitable for implementat...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-009-0310-0
更新日期:2009-05-01 00:00:00
abstract::We analyzed cyclic enzyme systems, one of the best candidates for biochemical switching devices, especially focusing on their control mode against external perturbations. Since these systems have the reliability of ON-OFF types of operation (McCulloch-Pitts' neuronic equation), we shall present here the mechanical dif...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00363938
更新日期:1988-01-01 00:00:00
abstract::Color vision in humans is independent over a wide range of the spectral composition of the illuminating light (Young 1807; Hering 1879). The retinex theory accounts for this color constancy by assuming that for each of the three waveband channels determined by the retinal cones a global lightness record of the scene i...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00338814
更新日期:1987-01-01 00:00:00
abstract::Many neurons at the sensory periphery receive periodic input, and their activity exhibits entrainment to this input in the form of a preferred phase for firing. This article describes a modeling study of neurons which skip a random number of cycles of the stimulus between firings over a large range of input intensitie...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00198810
更新日期:1994-01-01 00:00:00
abstract::The mechanisms that control the limbs position during rhythmic voluntary oscillations were investigated in ten subjects, who were asked to synchronise the lower peak of their hand or foot rhythmic oscillations to a metronome beat. The efficacy of the "position control" was estimated by measuring the degree of synchron...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-007-0159-z
更新日期:2007-08-01 00:00:00
abstract::Synchronization of the oscillatory discharge of cortical neurons could be a part of the mechanism that is involved in cortical information processing. On the assumption that the basic functional unit is the column composed of local excitatory and inhibitory cells and generating oscillatory neural activity, a network m...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00202761
更新日期:1994-01-01 00:00:00
abstract::In the context of the models of structure from motion visual processing, we propose that the optic-flow field is a source of information for the perception of the curvature of a smooth surface in motion. In particular, it is shown how the spin variation (SV), a second spatial derivative of the retinal velocity field, ...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00198096
更新日期:1990-01-01 00:00:00
abstract::Earlier experimental studies by one of us (Kelso, 1981a, 1984) have shown that abrupt phase transitions occur in human hand movements under the influence of scalar changes in cycling frequency. Beyond a critical frequency the originally prepared out-of-phase, antisymmetric mode is replaced by a symmetrical, in-phase m...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00336922
更新日期:1985-01-01 00:00:00
abstract::Temporal information processing was studied in humans attempting to tap a key in synchrony with a metronome whose base period was subjected to subliminal random changes. Statistical measures of the sequential timing of metronome and key-tap events were compared with similar time series generated by computer-simulated ...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00319511
更新日期:1987-01-01 00:00:00
abstract::The detection of small radially symmetric targets was studied using a subthreshold summation paradigm. Small disc and disc-like patterns with diameters up to 0.60 were used for superposition on Bessel functions of zero order, subthreshold contrast and various spatial frequencies. Contrast interrelation functions prove...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s004220170005
更新日期:2001-01-01 00:00:00
abstract::Compared to all other hearing animals, insects are the smallest ones, both in absolute terms and in relation to the wavelength of most biologically relevant sounds. The ears of insects can be located at almost any possible body part, such as wings, legs, mouthparts, thorax or abdomen. The interaural distances are gene...
journal_title:Biological cybernetics
pub_type: 杂志文章,评审
doi:10.1007/s00422-015-0672-4
更新日期:2016-10-01 00:00:00
abstract::We propose a mathematical model of the human hypothalamus-anterior pituitary-thyroid system regulating basal metabolism, and practice computer simulation concerning primary thyropathy such as Graves' disease, hypothyroidism, T4-toxicosis and T3-toxicosis by use of this model. In order to throw light on properties of t...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00336982
更新日期:1985-01-01 00:00:00
abstract::This paper concerns the use of tracking studies to test a theoretical account of the information processing performed by the human CNS during control of movement. The theory provides a bridge between studies of reaction time and continuous tracking. It is proposed that the human CNS includes neuronal circuitry to comp...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00364156
更新日期:1988-01-01 00:00:00
abstract::Stable signal transmission is crucial for information processing by the brain. Synfire-chains, defined as feed-forward networks of spiking neurons, are a well-studied class of circuit structure that can propagate a packet of single spikes while maintaining a fixed packet profile. Here, we studied the stable propagatio...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-008-0246-9
更新日期:2008-08-01 00:00:00
abstract::Simulations of neural activity are commonly based on differential equations. We address the question what can be achieved with a simplified discrete model. The proposed model resembles artificial neural networks enriched with additional biologically inspired features. A neuron has several states, and the state transit...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/s00422-020-00826-w
更新日期:2020-06-01 00:00:00
abstract::The application of an electronic real time emulator for biology-inspired pulse processing neural networks (BPN) to recognition and temporal tracking of discrete impulse patterns via delay adaptation is demonstrated. The electronic emulation includes biologically plausible features, such as asynchronous impulses, membr...
journal_title:Biological cybernetics
pub_type: 杂志文章
doi:10.1007/BF00206711
更新日期:1996-05-01 00:00:00