Multifetal pregnancies: evolution of methods of initiation and impact of REI certification for patients seeking reduction.

Abstract:

OBJECTIVE:Multifetal pregnancy as a result of ovulation induction (OI) and assisted reproductive technologies (ART) correlate with Board certification in reproductive endocrinology and infertility (REI). DESIGN:Retrospective chart analysis of 304 patients referred to Wayne State University (WSU) and Thomas Jefferson University (TJU) for multifetal pregnancy reduction (MFPR) from March 1986 to January 1995 compared to 275 patients referred from January 1 to December 31, 2000 at MCP Hahnemann University. MATERIAL AND METHODS:Chart review for fetal number, pregnancy generation (OI or ART) and physician REI Board certification from the American Board of Specialties Obstetrics and Gynecology. Information was available on 296 of 304 patients studied in the 1986-1995 WSU cohort and 275 patients studied from the MCP Hahnemann 2000 cohort. RESULTS:Analysis of 296 multifetal pregnancies at WSU and TJU for REI Board status showed non-REI Board-certified (NREI) physicians generated 174 pregnancies with quadruplets or more compared to 122 quadruplets or more by REI Board-certified physicians. Board certification did not impact quadruplet or more rates for OI or ART (p < 0.368). Of 275 patients with triplets or more at MCP Hahnemann, 156 (56.7%) were from ARTs versus 41.2% from 1986-1995 (chi(2) = 13.1, p < 0.001). Quintuplets or more decreased from 18.5 to 9.7% (chi(2) = 8.3, p = 0.004), and for REIs from 22.1 to 9.6% (chi(2) = 4.7, p < 0.01), while 14.4% of cases coming from non-REIs had quintuplets versus 9.6% from REIs (p = NS). CONCLUSIONS:Cases of MFPR from ARTs have risen, while percentage of cases with quintuplets have fallen in half. We found no difference in quintuplets between REIs and non-REIs overall, but REI quintuplets fell significantly, and NREI has not.

journal_name

Fetal Diagn Ther

authors

Calhoun B,Evans MI,Krivchenia EL,Waters T,Urban AJ,Morgan P,Hume RF,Wapner RJ

doi

10.1159/000068550

keywords:

subject

Has Abstract

pub_date

2003-03-01 00:00:00

pages

132-6

issue

2

eissn

1015-3837

issn

1421-9964

pii

68550

journal_volume

18

pub_type

杂志文章
  • Does intervention in utero preserve the obstructed kidneys of fetal lambs? A radiological and pathological study.

    abstract:OBJECTIVE:Ureteropelvic junction obstruction is a common cause of end-stage pediatric nephropathy. Our aim was to investigate whether in utero decompression can influence its development. METHODS:A silastic tube was tied around the superior segment of the left ureter to cause partial unilateral obstruction in 22 fetal...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000320966

    authors: Sun J,Wang F,Deng G,Mo J

    更新日期:2010-01-01 00:00:00

  • Perinatal outcome of conservative management versus fetal intervention for twin reversed arterial perfusion sequence with a small acardiac twin.

    abstract:OBJECTIVE:To examine the outcomes of patients with twin reversed arterial perfusion (TRAP) sequence in which the acardiac twin was

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000295176

    authors: Jelin E,Hirose S,Rand L,Curran P,Feldstein V,Guevara-Gallardo S,Jelin A,Gonzales K,Goldstein R,Lee H

    更新日期:2010-01-01 00:00:00

  • Successful fetal intervention for congenital high airway obstruction syndrome.

    abstract:INTRODUCTION:Complete congenital high airway obstruction syndrome (CHAOS) usually leads to stillbirth or death within minutes of delivery. We describe the management and long-term follow-up of a baby with a prenatally diagnosed airway obstruction. CASE:Because of progressive hydrops fetalis, massive ascites and everte...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000063179

    authors: Paek BW,Callen PW,Kitterman J,Feldstein VA,Farrell J,Harrison MR,Albanese CT

    更新日期:2002-09-01 00:00:00

  • Fetal scalp lactate microsampling for non-reassuring fetal status during labor: a prospective observational study.

    abstract:OBJECTIVE:The aim was to study the predictive value and feasibility of fetal scalp lactate microsampling in the management of non-reassuring fetal status during labor. METHODS:A prospective observational study was conducted on cord blood gas samplings from 7,617 singleton and cephalic deliveries at > or =37 weeks of g...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000262281

    authors: Ramanah R,Martin A,Clement MC,Maillet R,Riethmuller D

    更新日期:2010-01-01 00:00:00

  • Fetal presentation of long QT syndrome--evaluation of prenatal risk factors: a systematic review.

    abstract:OBJECTIVE:This systematic review evaluated the existence of risk factors for the fetal manifestation of long QT syndrome (LQTS). METHODS:Prenatal cardiac findings suggestive of fetal LQTS were studied using 30 English literature reports extracted from the Pubmed database (1979 to December 2011) using the search terms ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000339150

    authors: Ishikawa S,Yamada T,Kuwata T,Morikawa M,Yamada T,Matsubara S,Minakami H

    更新日期:2013-01-01 00:00:00

  • Prognostic value of change in amniotic fluid color during labor.

    abstract:OBJECTIVE:Evidence of meconium-stained amniotic fluid (AF) during labor suggests implementation of close monitoring of fetal well-being. We have investigated whether the presence of meconium in the AF on admission for labor is as important a predictor of neonatal outcome as a change in AF color during labor. METHODS:A...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000081359

    authors: Locatelli A,Regalia AL,Patregnani C,Ratti M,Toso L,Ghidini A

    更新日期:2005-01-01 00:00:00

  • Role of ultrasonography in pregnancies with marker chromosome aneuploidy.

    abstract::The objective of this report was to evaluate the effect of ultrasonographic (US) findings on pregnancy management in patients with marker chromosome (MC) aneuploidy ascertained through prenatal diagnosis. From 1989 through June 1993, 15,522 prenatal diagnostic procedures were performed for accepted indications. Charts...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000264230

    authors: Hume RF Jr,Drugan A,Ebrahim SA,Johnson MP,Isada NB,Reichler A,Evans MI

    更新日期:1995-05-01 00:00:00

  • Sonographic screening for trisomy 21: fetal humerus:foot length ratio, a useful new marker.

    abstract::We have analyzed morphometric measurements from midgestational fetal necropsies and shown that arm and foot lengths are linear relationships versus gestational age (GA). Using foot length as the GA determinant, we found that the ratio of arm:foot length was also a linear relationship and was decreased in trisomy 21 fe...

    journal_title:Fetal diagnosis and therapy

    pub_type: 临床试验,杂志文章

    doi:10.1159/000263920

    authors: Johnson MP,Michaelson JE,Barr M Jr,Treadwell MC,Isada NB,Dombrowski MP,Pryde PG,Addis J,Evans MI

    更新日期:1994-03-01 00:00:00

  • Screening for Sex Chromosome Aneuploidy by Cell-Free DNA Testing: Patient Choice and Performance.

    abstract:OBJECTIVE:To study patient choice regarding testing for sex chromosome aneuploidy (SCA) and the performance of cell-free DNA (cfDNA) screening for SCA. METHODS:Patient choice regarding screening for SCA and factors influencing this choice were evaluated in a single center. In a subsequent two-center study, cases that ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000479507

    authors: Bevilacqua E,Ordóñez E,Hurtado I,Rueda L,Mazzone E,Cirigliano V,Jani JC

    更新日期:2018-01-01 00:00:00

  • Prenatal Prediction of the Type of Omphalocele Closure by Different Medical Consultants.

    abstract:INTRODUCTION:To evaluate differences between consultants of different disciplines in the prenatal prediction of the type of postnatal surgical closure of an omphalocele. MATERIAL AND METHODS:Twenty-one images of prenatally detected omphaloceles prior to 24 weeks of gestation were included. A standardized form provided...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000430439

    authors: Peters NC,Visser 't Hooft ME,Eggink AJ,Tibboel D,Ursem N,Wijnen RM,Bonsel GJ,Cohen-Overbeek TE

    更新日期:2016-01-01 00:00:00

  • Obstetric evolution of pregnancies obtained from donated oocytes.

    abstract::Of 44 pregnancies obtained at the Tenon Maternity Hospital by in vitro fertilization (IVF) using donated oocytes, 25 have already been completed by spontaneous delivery or cesarean section: 22 (88%) single; 2 (8%) twins, and 1 (4%) triple. The most frequently seen complications of pregnancy were hypertension (16%) and...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000263647

    authors: Cornet D,Antoine JM,Casanova S,Uzan S,Mandelbaum J,Plachot M,Salat-Baroux J

    更新日期:1992-01-01 00:00:00

  • Two-Dimensional Ultrasound Evaluation of the Fetal Cerebral Aqueduct: Improving the Antenatal Diagnosis and Counseling of Aqueductal Stenosis.

    abstract:OBJECTIVE:To describe a technique for the visualization and measurement of cerebral aqueduct diameter through a 2D sagittal median plane, and to report its aspect and measurement in fetuses with aqueductal stenosis (AS). METHODS:This was a cross-sectional study of 207 morphologically normal fetuses in low-risk pregnan...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000458439

    authors: Viñals F,Ruiz P,Quiroz G,Guerra FA,Correa F,Martínez D,Puerto B

    更新日期:2017-01-01 00:00:00

  • Prenatal imaging of occipital encephaloceles.

    abstract:INTRODUCTION:This retrospective study aims to describe systematically the fetal cerebral MR morphology in cases with occipital meningoencephaloceles using standard and advanced fetal MRI techniques. MATERIAL AND METHODS:The 1.5-tesla MR examinations (T1- and T2-weighted imaging, echo planar imaging, EPI, diffusion-wei...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000366159

    authors: Kasprian GJ,Paldino MJ,Mehollin-Ray AR,Shetty A,Williams JL,Lee W,Cassady CI

    更新日期:2015-01-01 00:00:00

  • Prenatal diagnosis of lissencephaly by magnetic resonance image.

    abstract::Two cases of lissencephaly were prenatally diagnosed by a magnetic resonance image (MRI). Smooth surface of brain and remarkable sylvian fissure, which were barely detectable by ultrasound, were easily observed in MRI. MRI is the most appropriate tool in diagnosing lissencephaly. ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000263748

    authors: Okamura K,Murotsuki J,Sakai T,Matsumoto K,Shirane R,Yajima A

    更新日期:1993-01-01 00:00:00

  • Optimal interval between middle cerebral artery velocity measurements when monitoring pregnancies complicated by red cell alloimmunization.

    abstract:OBJECTIVE:To evaluate the optimal interval between middle cerebral artery (MCA) Doppler measurements when monitoring pregnancies complicated by red cell alloimmunization. METHODS:Thirty-nine fetal blood samplings (FBS) performed on 24 pregnant women with red blood cell alloimmunization followed up using both MCA peak ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000089043

    authors: Bartha JL,Abdel-Fattah SA,Hunter A,Denbow M,Kyle P,Soothill PW

    更新日期:2006-01-01 00:00:00

  • Why cell culture is successful after early amniocentesis.

    abstract::The current interest in early amniocentesis as a possible alternative to chorion villus sampling has driven many centres to attempt cell culture from first trimester amniotic fluid. This study examines the cellular content of 125 amniotic fluid specimens collected between 8 and 18 weeks of gestation and shows that the...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000263628

    authors: Byrne D,Azar G,Nicolaides K

    更新日期:1991-01-01 00:00:00

  • Membrane Separation and Perinatal Outcomes after Laser Treatment for Twin-Twin Transfusion Syndrome.

    abstract:INTRODUCTION:Postoperative membrane separation is a complication of selective laser photocoagulation of communicating vessels (SLPCV) for the treatment of twin-twin transfusion syndrome (TTTS). OBJECTIVE:The aim of this work was to determine whether a quantitative grading system of membrane separation following SLPCV ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000504361

    authors: De Zoysa MY,Chon AH,Korst LM,Llanes A,Chmait RH

    更新日期:2020-01-01 00:00:00

  • Changes in blood flow velocity waveforms following fetal blood sampling.

    abstract::The umbilical artery, aorta, and middle cerebral artery pulsatility indices were investigated by pulsed Doppler ultrasound in 73 fetuses at 18-37 weeks of gestation, before and after fetal blood sampling performed either at the placental cord insertion (n = 46) or at the intrahepatic vein (n = 27). At the end of the p...

    journal_title:Fetal diagnosis and therapy

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000264251

    authors: Zoppini C,Brioschi D,Tassis B,Zuliani G,Kustermann A,Nicolini U

    更新日期:1995-09-01 00:00:00

  • Increased nuchal translucency in a case of long-chain 3-hydroxyacyl- coenzyme A dehydrogenase deficiency.

    abstract::We present a case where the embryo showed an increased nuchal edema and a metabolic disorder. At 31 weeks of gestation the fetus developed a cardiomegaly and a hydrops. In this case, a long-chain 3-hydroxacyl-coenzyme A dehydrogenase deficiency (LCHAD deficiency) was confirmed by biochemical investigations in cultured...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000021029

    authors: Tercanli S,Uyanik G,Hösli I,Cagdas A,Holzgreve W

    更新日期:2000-11-01 00:00:00

  • Venous-arterial Doppler ratios in the prediction of acidemia at birth in pregnancies with placental insufficiency.

    abstract:OBJECTIVES:Investigate the prediction of birth acidemia in pregnancies with placental insufficiency using two newly created venous-arterial Doppler ratios: pulsatility index (PI) of the ductus venosus (DV) over PI of the middle cerebral artery (MCA) and PI of the DV over PI of the umbilical artery and establish cut-off...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000093883

    authors: Carvalho FH,Moron AF,Mattar R,Murta CG,Santana RM,Barbosa MM,Torloni MR,Vasques FA

    更新日期:2006-01-01 00:00:00

  • Thoraco-omphalopagus conjoined twins detected at as early as 9 weeks of gestation: transvaginal two-dimensional ultrasound, color Doppler and fetoplacental Doppler velocity waveform findings.

    abstract::Here we report a case of conjoined twins that were diagnosed antenatally by routine two-dimensional transvaginal ultrasound examination at as early as the 9th week of gestational age. The fetuses were of the thoraco-omphalopagus type and were sharing the liver, as confirmed by color Doppler. There was a reversed flow ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000093893

    authors: Basgül A,Kavak ZN,Sezen D,Basgul A,Gokaslan H

    更新日期:2006-01-01 00:00:00

  • Age of gestation (size) at embryonic demise: tailoring counseling for lethal versus potentially viable aneuploidy.

    abstract::The incidence of chromosomal abnormalities in spontaneous abortions is much higher than commonly appreciated. Using postmortem chorionic villus sampling (as we have previously described), our much increased yield of results allows us to divide embryos into two groups based upon potential viability. Embryonic size at t...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000263821

    authors: Drugan A,Johnson MP,Isada NB,Evans MI

    更新日期:1993-05-01 00:00:00

  • Second- to Third-Trimester Longitudinal Growth Assessment for the Prediction of Largeness for Gestational Age and Macrosomia in an Unselected Population.

    abstract:BACKGROUND:Prenatal detection of excessive growth remains inaccurate. Most strategies rely on a single cross-sectional evaluation of fetal size during the third trimester. OBJECTIVES:To compare second- to third-trimester longitudinal growth assessment with cross-sectional evaluation at the third trimester in the predi...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000477460

    authors: Caradeux J,Eixarch E,Mazarico E,Basuki TR,Gratacós E,Figueras F

    更新日期:2018-01-01 00:00:00

  • Evaluation of First-Trimester Physiological Midgut Herniation Using Three-Dimensional Ultrasound.

    abstract:INTRODUCTION:The aim of this study was to investigate the development of midgut herniation in vivo using three-dimensional (3D) ultrasonographic volume and distance measurements and to create reference data for physiological midgut herniation in ongoing pregnancies in a tertiary hospital population. MATERIALS AND METH...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000489260

    authors: Bogers H,Baken L,Cohen-Overbeek TE,Koning AHJ,Willemsen SP,van der Spek PJ,Exalto N,Steegers EAP

    更新日期:2019-01-01 00:00:00

  • Epidural local anesthetics: a novel treatment for fetal growth retardation?

    abstract:BACKGROUND:Chronically compromised uterine perfusion may lead to placental insufficiency and subsequent intrauterine growth restriction (IUGR). Various therapeutic approaches (e.g. vasodilators, low-dose aspirin, intravenous glucose infusion, and hemodilution) are often of limited efficacy. Local anesthetics have been ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 临床试验,杂志文章

    doi:10.1159/000083907

    authors: Strümper D,Louwen F,Durieux ME,Gramke HF,Stuessel J,Marcus-Soekarman D,Van Aken H,Marcus MA

    更新日期:2005-05-01 00:00:00

  • Cell-Free DNA Analysis in Maternal Blood: Differences in Estimates between Laboratories with Different Methodologies Using a Propensity Score Approach.

    abstract:OBJECTIVES:To evaluate the failure rate and performance of cell-free DNA (cfDNA) testing, mainly in terms of detection rates for trisomy 21, performed by 2 laboratories using different analytical methods. METHODS:cfDNA testing was performed on 2,870 pregnancies with the HarmonyTM Prenatal Test using the targeted digit...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000489124

    authors: Bevilacqua E,Jani JC,Letourneau A,Duiella SF,Kleinfinger P,Lohmann L,Resta S,Cos Sanchez T,Fils JF,Mirra M,Benachi A,Costa JM

    更新日期:2019-01-01 00:00:00

  • Congenital laryngeal cyst: benefits of prenatal diagnosis and multidisciplinary perinatal management.

    abstract::Congenital laryngeal cysts are rare and can cause upper airway obstruction if they are misdiagnosed. We describe a case of large vallecular cyst diagnosed at 33 weeks of gestation. The purpose of an early diagnosis is to establish a careful perinatal management. If the airway is compromised, a multidisciplinary medica...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000077969

    authors: Busuttil M,Einaudi MA,Hassid S,Chau C,Shojai R,Thomachot L,D'Ercole C,Gire C

    更新日期:2004-07-01 00:00:00

  • Plasma cysteine concentrations in uncomplicated pregnancies.

    abstract:OBJECTIVE:To measure levels of total plasma cysteine, homocysteine, cysteinylglycine and glutathione of normotensive primiparous pregnant women in the second and the third trimester. METHODS:Two consecutive blood samples were taken from 65 healthy primiparous women in the 19th to 21st weeks of pregnancy and then in th...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000100785

    authors: Viskova H,Vesela K,Janosikova B,Krijt J,Visek JA,Calda P

    更新日期:2007-01-01 00:00:00

  • Which stem cells should be used for transplantation?

    abstract::In view of the ever-increasing demand for human stem cells for transplantation, we initiated in vitro and in vivo studies of human fetal bone marrow stem/progenitor cells derived from lost pregnancies at 16-20 weeks. Utilizing non-human primates as models, we demonstrated that fetal tissue has distinctive biological a...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000074252

    authors: Michejda M

    更新日期:2004-01-01 00:00:00

  • Validation of correction factors for serum markers for first-trimester Down syndrome screening in singleton pregnancies conceived with assisted reproduction.

    abstract:OBJECTIVE:To validate previously computed correction factors for free β-human chorionic gonadotrophin (fβ-hCG) and pregnancy-associated plasma protein-A (PAPP-A) in in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) pregnancies with hormone treatment and to determine the effect on false-positive r...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000355527

    authors: Engels MA,Pajkrt E,Groot DT,Schats R,Twisk JW,van Vugt JM

    更新日期:2013-01-01 00:00:00