Optimal interval between middle cerebral artery velocity measurements when monitoring pregnancies complicated by red cell alloimmunization.

Abstract:

OBJECTIVE:To evaluate the optimal interval between middle cerebral artery (MCA) Doppler measurements when monitoring pregnancies complicated by red cell alloimmunization. METHODS:Thirty-nine fetal blood samplings (FBS) performed on 24 pregnant women with red blood cell alloimmunization followed up using both MCA peak systolic velocity and time-averaged mean velocity measurements on weekly basis. RESULTS:In total, 65.5 and 37.5% of women with moderate or severe fetal anemia had abnormal MCA Doppler values 1 and 2 weeks, respectively, before FBS was performed. CONCLUSIONS:A weekly assessment of women at risk for fetal anemia is optimal in most of the cases even though 35.5% of cases of moderate or severe fetal anemia are expected to have normal Doppler measurements the week before the decision of doing an FBS is made.

journal_name

Fetal Diagn Ther

authors

Bartha JL,Abdel-Fattah SA,Hunter A,Denbow M,Kyle P,Soothill PW

doi

10.1159/000089043

keywords:

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

22-5

issue

1

eissn

1015-3837

issn

1421-9964

pii

89043

journal_volume

21

pub_type

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