Computer-assisted analysis of lymph nodes detected by EUS in patients with esophageal carcinoma.

Abstract:

BACKGROUND:EUS determination of lymph nodal spread of intestinal cancer based on imaging alone is problematic. A noninvasive, reliable means of determining tumor spread to lymph nodes is desirable. This study investigated the feasibility of a computer-assisted evaluation of lymph nodes detected by EUS in patients with esophageal carcinoma. METHODS:Images were obtained during EUS of esophageal lesions and correlated with histopathologic findings after esophagectomy. Sonographic features of echogenicity, whole-node heterogeneity, and regional variability were assessed by computerized image analysis in patients with benign versus malignant lymphadenopathy. RESULTS:Malignant lymph nodes were hypoechoic compared with benign lymph nodes (p < 0.04). Whole lymph node heterogeneity was increased in malignant lymph nodes (p < 0.004). Regional variability was greater for benign lymph nodes. CONCLUSIONS:These data support the feasibility of a computer-assisted system for analysis of lymph node metastasis in patients with esophageal carcinoma. Further refinements of such a system could increase the accuracy of EUS staging of tumors.

journal_name

Gastrointest Endosc

authors

Loren DE,Seghal CM,Ginsberg GG,Kochman ML

doi

10.1067/mge.2002.128920

keywords:

subject

Has Abstract

pub_date

2002-11-01 00:00:00

pages

742-6

issue

5

eissn

0016-5107

issn

1097-6779

pii

S0016-5107(02)70131-4

journal_volume

56

pub_type

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