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Primary cerebral sarcoid granuloma: the importance of definitive diagnosis in the high-risk patient population.

Abstract：

:Sarcoidosis of the central nervous system has been variously reported in 5-15% of all sarcoid patients. However, presentation of sarcoidosis as an isolated 'intracranial tumor' is rare. A 35-year-old African-American woman presented with intractable headaches. Neuroimaging revealed a tumor that was suggestive of a glioma or meningioma or metastasis. The symptoms did not respond to steroids, and an open biopsy of the lesion revealed non-caseating granuloma. A thorough work-up for systemic sarcoidosis was negative. The patient remains symptom-free at a 2-year follow-up. Primary sarcoid granuloma of the brain is rare. Once systemic disease has been excluded, early tissue diagnosis is crucial. This is particularly relevant for patients in the high-risk population before considering empirical radiosurgery.

journal_name

Clin Neurol Neurosurg

journal_title

Clinical neurology and neurosurgery

authors

Vannemreddy PS,Nanda A,Reddy PK,Gonzalez E

doi

10.1016/s0303-8467(02)00012-4

keywords:

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

289-92

issue

4

eissn

0303-8467

issn

1872-6968

pii

S0303846702000124

journal_volume

104

pub_type

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