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Successful treatment with voriconazole of fungal cerebral abscess due to Cladophialophora bantiana.

Abstract：

:We report the first successfully treated case of Cladophialophora bantiana cerebral abscess with the relatively new antifungal agent voriconazole. Infection with this organism is often fatal. A 64-year-old man presented to our institution with progressive neurologic symptoms due to a brain abscess. A stereotactic brain biopsy confirmed the pathogen as C. bantiana. We discuss the successful treatment of this patient, and review the pharmacological actions of voriconazole and the literature on the treatment of this organism. Previously considered a rare cause of cerebral abscess, C. bantiana fungal infections have become more common in recent years. Aggressive and continuous treatment with voriconazole may offer an improved chance of survival in these patients.

journal_name

Clin Neurol Neurosurg

journal_title

Clinical neurology and neurosurgery

authors

Lyons MK,Blair JE,Leslie KO

doi

10.1016/j.clineuro.2004.11.020

keywords:

subject

Has Abstract

pub_date

2005-10-01 00:00:00

pages

532-4

issue

6

eissn

0303-8467

issn

1872-6968

pii

S0303-8467(04)00195-7

journal_volume

107

pub_type

杂志文章

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