Does botulinum toxin injection in parotid glands interfere with the swallowing dynamics of Parkinson's disease patients?

Abstract:

BACKGROUND:During recent years, sialorrhea in Parkinson's disease (PD) has been treated with botulinum toxin type A (BT-A); however, there are no data describing its effects on swallowing dynamics in this group of patients. OBJECTIVE:To investigate whether injection of BT-A into the parotid glands interferes with the oropharyngeal swallowing dynamics of patients with Parkinson's disease. METHODS:Sixteen patients with diurnal sialorrhea were selected and evaluated during the "on" period by a standardized questionnaire and swallowing videofluoroscopy before and 30 days after ultrasound-guided BT-A injection into the parotid glands. RESULTS:A decrease in sialorrhea was observed in all studied patients. Silent laryngeal penetration was observed in three patients, and silent aspiration was observed in two of them. There were no changes in swallowing dynamics when comparing patients before and after BT-A parotid injection (p=1), suggesting similar levels of dysphagia in the two measurements. CONCLUSION:BT-A injection into parotid glands does not interfere with the oropharyngeal swallowing dynamics of PD patients.

journal_name

Clin Neurol Neurosurg

authors

Nóbrega AC,Rodrigues B,Melo A

doi

10.1016/j.clineuro.2008.12.007

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

430-2

issue

5

eissn

0303-8467

issn

1872-6968

pii

S0303-8467(08)00428-9

journal_volume

111

pub_type

杂志文章
  • Outcome of diabetes insipidus in patients with Rathke's cleft cysts.

    abstract:OBJECTIVES:It is well-known that Rathke's cleft cysts (RCCs) infrequently cause headache, endocrinological dysfunction, and visual disturbance, and in rare cases, cause diabetes insipidus (DI). Although surgical evacuation of the cyst content can result in high rates of symptomatic improvement, not only the treatment e...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2018.02.031

    authors: Oishi M,Hayashi Y,Sasagawa Y,Kita D,Tachibana O,Nakada M

    更新日期:2018-04-01 00:00:00

  • Symptomatic and asymptomatic abnormalities in patients with lumbosacral radicular syndrome: Clinical examination compared with MRI.

    abstract:OBJECTIVE:To determine the frequency of symptomatic and asymptomatic herniated discs and root compression in patients with lumbosacral radicular syndrome (LRS) and to correlate clinical localization with MRI findings. METHODS:Fifty-seven patients with unilateral LRS were included in the study. Using the visual analogu...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2005.10.003

    authors: van Rijn JC,Klemetso N,Reitsma JB,Majoie CB,Hulsmans FJ,Peul WC,Bossuyt PM,Heeten GJ,Stam J

    更新日期:2006-09-01 00:00:00

  • Impact of the per-operatory application of GLIADEL wafers (BCNU, carmustine) in combination with temozolomide and radiotherapy in patients with glioblastoma multiforme: efficacy and toxicity.

    abstract:PURPOSE:For the last few years wafers of Gliadel have been inserted into the operation cavity in patients with glioblastoma multiforme. This is followed by concurrent radio-chemotherapy with temozolomide (TMZ) according to the Stupp protocol. Only a few studies have investigated this kind of treatment regimen and the i...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2012.02.056

    authors: Miglierini P,Bouchekoua M,Rousseau B,Hieu PD,Malhaire JP,Pradier O

    更新日期:2012-11-01 00:00:00

  • Subcutaneous low molecular weight heparin in place of heparin infusion during warfarin dose optimisation in cerebral ischaemia.

    abstract::We explored the feasibility of using subcutaneous low-molecular-weight-heparin (LMWH) injections in place unfractionated heparin (UFH) while anticoagulating patients with cerebral ischemia. In this open-labeled, prospective study, patients admitted to our hospital with transient ischemic attacks or stroke requiring an...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0303-8467(98)00039-0

    authors: Venketasubramanian N,Chua HC

    更新日期:1998-09-01 00:00:00

  • Axonal damage in multiple sclerosis: a complex issue in a complex disease.

    abstract::Multiple sclerosis is no longer considered to simply be an autoimmune demyelinating disease. Axonal destruction is another central pathological feature and a contributor to the accumulating disability of disease progression. The mechanism underlying axonal pathology has not been fully clarified but does not appear to ...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.clineuro.2004.02.017

    authors: Grigoriadis N,Ben-Hur T,Karussis D,Milonas I

    更新日期:2004-06-01 00:00:00

  • Meige's syndrome: A cranial dystonia treated with bilateral pallidal deep brain stimulation.

    abstract:BACKGROUND:Meige's syndrome is a rare form of segmental dystonia characterized by blepharospasm and oromandibular dystonia. Medical treatment including botulinum toxin injections usually present disappointing results. The experience on Deep Brain Stimulation (DBS) in the treatment of Meige's syndrome and other segmenta...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2009.12.005

    authors: Markaki E,Kefalopoulou Z,Georgiopoulos M,Paschali A,Constantoyannis C

    更新日期:2010-05-01 00:00:00

  • Stereotactic radio surgery and radio frequency rhizotomy for trigeminal neuralgia in multiple sclerosis: A single institution experience.

    abstract:OBJECTIVES:For patients with medically unresponsive trigeminal neuralgia (TN), surgical options include micro vascular decompression (MVD), radiofrequency rhizotomy (RF), and stereotactic radio surgery (SRS). Multiple sclerosis (MS) is a demyelinating condition that can be associated with TN, but is not amenable to tre...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2017.09.004

    authors: Holland MT,Teferi N,Noeller J,Swenson A,Smith M,Buatti J,Hitchon PW

    更新日期:2017-11-01 00:00:00

  • Focal burst suppression on intra-operative electrocorticography does not affect the surgical outcome in patients with temporal lobe epilepsy.

    abstract:OBJECTIVE:The aim of this study was to investigate the burst suppression (BS) pattern on intra-operative electrocorticography (ECoG) in patients with temporal lobe epilepsy (TLE) and the surgical outcome. PATIENTS AND METHODS:From January 2017 to June 2017, 45 patients with TLE underwent temporal lobe resection with i...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2020.105785

    authors: Xu C,Yu T,Zhang X,Zhang G,Zhuang P,Wang Y,Li Y

    更新日期:2020-06-01 00:00:00

  • A case of urinary retention in the early stages of herpes simplex virus type-1 encephalitis.

    abstract::A 70-year-old man developed urinary retention in the early stages of herpes simplex virus (HSV) type-1 encephalitis. A nerve conduction study suggested latent myeloradiculitis. This is the first report of human herpes simplex virus-1 encephalitis followed by urinary retention at early stage from the onset like the Els...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2017.03.011

    authors: Fukuoka T,Nakazato Y,Miyake A,Tamura N,Araki N,Yamamoto T

    更新日期:2017-06-01 00:00:00

  • Diagnostic performance of iodine-123-metaiodobenzylguanidine scintigraphy in differential diagnosis between Parkinson's disease and multiple-system atrophy: a systematic review and a meta-analysis.

    abstract:BACKGROUND AND PURPOSE:This study was designed to review the diagnostic performance of iodine-123-metaiodobenzylguanidine (MIBG) scintigraphy in differential diagnosis between Parkinson's disease (PD) and multiple-system atrophy (MSA). METHODS:A comprehensive computer literature search of studies published through Mar...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.clineuro.2011.09.004

    authors: Treglia G,Stefanelli A,Cason E,Cocciolillo F,Di Giuda D,Giordano A

    更新日期:2011-12-01 00:00:00

  • Postural instability differences between idiopathic normal pressure hydrocephalus and Parkinson's disease.

    abstract:OBJECTIVES:We investigated the differences in postural control disability between idiopathic normal pressure hydrocephalus (iNPH) and Parkinson's disease (PD). PATIENTS AND METHODS:Twenty-seven iNPH patients, 20 PD patients, and 20 healthy controls (HCs) were examined using the Timed Up and Go test (TUG) and a force p...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2018.01.012

    authors: Nikaido Y,Akisue T,Kajimoto Y,Tucker A,Kawami Y,Urakami H,Iwai Y,Sato H,Nishiguchi T,Hinoshita T,Kuroda K,Ohno H,Saura R

    更新日期:2018-02-01 00:00:00

  • Angiographic features, surgical management and outcomes of proximal middle cerebral artery aneurysms.

    abstract:OBJECTIVE:Understanding the microanatomy of the proximal middle cerebral artery (M1) and its early branches is very important for aneurysm surgery in this region. However, few articles provide detailed descriptions of such aneurysms. We report the angiographic characteristics of a series of M1 aneurysms and our experie...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2008.02.014

    authors: Park DH,Kang SH,Lee JB,Lim DJ,Kwon TH,Chung YG,Lee HK

    更新日期:2008-06-01 00:00:00

  • Checklist for cognitive and emotional consequences following stroke (CLCE-24): development, usability and quality of the self-report version.

    abstract:OBJECTIVE:In this paper a new checklist (CLCE-24) for identification of cognitive and emotional problems after stroke is presented. The CLCE-24 is intended to support a clinical interview by health care professionals other than the trained (neuro)psychologist. METHODS:Patients were interviewed with the CLCE-24, 6 mont...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2006.10.002

    authors: van Heugten C,Rasquin S,Winkens I,Beusmans G,Verhey F

    更新日期:2007-04-01 00:00:00

  • Endoscopic resection of cavernoma of foramen of Monro in a patient with familial multiple cavernomatosis.

    abstract::Intraventricular cavernomas are extremely infrequent and only 11 cases of cavernous hemangioma to occur at the foramen of Monro have been reported in the literature. This 56 years old patient was admitted with progressive and intractable headache of 10 days of evolution. He was known to suffer familial multiple cavern...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2008.05.011

    authors: Prat R,Galeano I

    更新日期:2008-09-01 00:00:00

  • The Utility of a Diagnostic Angiogram Following Mechanical Thrombectomy for Treatment of Acute Ischemic Stroke.

    abstract:OBJECTIVE:Digital subtraction angiography is the gold standard for diagnosis of vascular pathology. The value of angiography of non-target vessels following mechanical thrombectomy for the treatment of acute ischemic stroke (AIS) is unknown. PATIENTS AND METHODS:Consecutive patients treated with mechanical thrombectom...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2020.105842

    authors: Foreman PM,Wirtz MM,Fong R,Goren O,Schirmer CM,Dalal S,Weiner G,Griessenauer CJ

    更新日期:2020-07-01 00:00:00

  • Objective tremor registration during DBS surgery for essential tremor.

    abstract::Essential Tremor (ET) is characterized by a 4-12-Hz postural and kinetic tremor, most commonly affecting the upper limbs. Deep brain stimulation (DBS) of the thalamus (Vim) has been found to be highly effective in severe/refractory forms of ET. Intra-operative assessment of tremor is performed using clinical methods b...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2008.10.017

    authors: Papapetropoulos S,Gallo BV,Guevara A,Singer C,Mitsi G,Lyssikatos C,Jagid JR

    更新日期:2009-05-01 00:00:00

  • Peripheral neuropathy response to erythropoietin in type 2 diabetic patients with mild to moderate renal failure.

    abstract::This study assessed the added effect of 6 months of erythropoietin (EPO) administration in patients suffering from diabetic neuropathy with mild to moderate chronic kidney disease (CKD) managed with gabapentin. Twenty diabetic patients with mild to moderate CKD were included; 12 in gabapentin and 8 in EPO+gabapentin g...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2012.01.007

    authors: Hosseini-Zare MS,Dashti-Khavidaki S,Mahdavi-Mazdeh M,Ahmadi F,Akrami S

    更新日期:2012-07-01 00:00:00

  • The complementary value of Doppler-ultrasonography and ocular pneumoplethysmography according to Gee (OPG-Gee) in carotid obstructions.

    abstract::The results of the combination of CW-Doppler ultrasonography and OPG-Gee are described in 68 patients. The Doppler examination had a sensitivity of 92% and a specificity of 89%, the percentages for the OPG-Gee were 69 en 79. The combination of the Doppler examination with the OPG-Gee improves our positive predictive v...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/0303-8467(88)90026-1

    authors: Strik F

    更新日期:1988-01-01 00:00:00

  • Bioptically demonstrated Lafora disease without EPM2A mutation: a clinical and neurophysiological study of two sisters.

    abstract::Lafora disease (LD) is an autosomal recessive inherited form of progressive myoclonic epilepsy with dementia and ataxia, usually presenting in the second decade of life and inexorably progressing until death. Neuropathological hallmarks are Lafora bodies, intracytoplasmic inclusions that can be found in neurons and in...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2003.07.003

    authors: Boccella P,Striano P,Zara F,Barbieri F,Sarappa C,Vacca G,de Falco FA,Striano S

    更新日期:2003-12-01 00:00:00

  • Radiotherapy in brain-stem gliomas in children.

    abstract::Twenty-one children with brain-stem glioma are discussed. Sixteen received radiotherapy and five were too sick to be irradiated. The mean survival was 3.4 weeks for the non-irradiated group and 8.7 months for the treated group, two of the latter being still alive five and ten months after diagnosis. From the literatur...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/0303-8467(79)90032-5

    authors: Ataç MS,Blaauw G

    更新日期:1979-01-01 00:00:00

  • Sensory perineuritis presented as a mononeuritis multiplex associated with livedo vasculitis.

    abstract::We report a 52-year-old patient affected by a mononeuritis multiplex and livedo vasculitis. Sural nerve biopsy showed mild thickening of the perineurium, vascular alterations with inflammatory cell infiltration in the perineurium, and remarkable loss of large and small myelinated fibers. A therapeutic trial of acetyls...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/s0303-8467(01)00111-1

    authors: Lee SS,Yoon TY

    更新日期:2001-04-01 00:00:00

  • Presence of the HLADR13 allele among Mexican Mestizos suggests a protective factor against relapsing-remitting multiple sclerosis (RRMS).

    abstract:BACKGROUND AND OBJECTIVE:Multiple sclerosis (MS) is a chronic demyelinating disease that affects the central nervous system. Researchers have looked for an association between relapsing-remitting MS (RRMS) and human leukocyte antigen (HLA) as risk or protective factor associated to ethnicity, which may add a partial ex...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2015.08.016

    authors: Flores J,Granados J,Alonso E,Rito Y,Ortega-Hernández E,Mena-Hernández L,Corona T

    更新日期:2015-11-01 00:00:00

  • Peripheral facial nerve paralysis in children: the value of routine diagnostic work-up studies.

    abstract::Acute facial nerve paralysis is a relatively common pediatric disorder. Idiopathic facial nerve palsy (Bell's palsy) has to be distinguished from other etiologies. Retrospective review of the results of routine diagnostic work-up studies of our patients, failed to reveal any clinically significant abnormalities and di...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/0303-8467(88)90007-8

    authors: Eshel G,Lahat E,Azizi E

    更新日期:1988-01-01 00:00:00

  • Recurrent forms of sporadic brachial plexus neuropathy. A report of two cases.

    abstract::Two patients presenting a relapsing form of sporadic brachial plexus neuropathy, the so-called Parsonage Turner syndrome, are reported. The diagnosis is based on clinical and electromyographic features. Recurrent attacks, although infrequently encountered, have been well described in the past. Sporadic cases of this s...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/s0303-8467(88)80014-3

    authors: Michotte A,Dierckx R,Deleu D,Herregodts P,Schmedding E,Bruyland M,Ebinger G

    更新日期:1988-01-01 00:00:00

  • Calcified cerebellopontine angle hematoma mimicking recurrent acoustic neurinoma.

    abstract::The authors describe a case of calcified, organized hematoma in the cerebellopontine angle which developed 20 years after subtotal removal of an acoustic neurinoma, presenting as a recurrence of acoustic neurinoma on computed tomography. It points out the difficulty in differentiating a recurrent tumor from an organiz...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/s0303-8467(88)80013-1

    authors: Ito M,Tajima A,Sato K,Ishii S

    更新日期:1988-01-01 00:00:00

  • Comparative safety and efficacy of percutaneous approaches for the treatment of trigeminal neuralgia: A systematic review and meta-analysis.

    abstract::Percutaneous treatments for trigeminal neuralgia (TN) include glycerol rhizotomy (GR), radiofrequency thermocoagulation (RF), and balloon compression (BC), which aim to provide pain relief by targeted injury to the trigeminal nerve pain fibers. All three techniques are well established and can provide immediate pain r...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.clineuro.2019.05.011

    authors: Texakalidis P,Xenos D,Tora MS,Wetzel JS,Boulis NM

    更新日期:2019-07-01 00:00:00

  • Aortic atheromas in stroke subgroups detected by multidetector computed tomographic angiography.

    abstract:BACKGROUND:The aim of this study was to investigate aortic atheromas in stroke subgroups. METHODS:Two hundred consecutive subjects had acute ischemic stroke confirmed by diffusion-weighted imaging (DWI) (195 cases) or computerized tomography (5 cases). Multidetector computed tomographic angiography (MDCTA) (16- or 64-...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2008.12.001

    authors: Kaya D,Yildiz E

    更新日期:2009-06-01 00:00:00

  • Vertebra-disc ratio as a new predictor for curve progression in early thoracic AIS with bracing treatment.

    abstract:OBJECTIVES:Previous studies have reported various predictors for curve progression in braced adolescent idiopathic scoliosis (AIS) patients. However, the reported predictors might be insufficient for patients with early AIS. The aim was to investigate whether the initial vertebra-disc ratio (VDR) could serve as an effe...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2019.04.012

    authors: Li S,Qiu Y,Zhu ZZ,Chen ZH,Chen X,Du CZ,Xu L,Zhou QS,Sun X

    更新日期:2019-06-01 00:00:00

  • Primary germinoma of the brain. Immunocytochemical demonstration of tumour cells in the cerebrospinal fluid.

    abstract::A patient is presented, who developed a suprasellar tumour. Stereotactical biopsy of the tumour revealed the diagnosis of a dysgerminoma. Immunocytochemical examination of the CSF showed neoplastic cells staining for human chorionic gonadotropin and for alpha-fetoprotein. The authors stress the possibility to diagnose...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/s0303-8467(86)80043-9

    authors: Stark E,Knehans A,Wurster U,Patzold U

    更新日期:1986-01-01 00:00:00

  • A five-generation family with occipital encephalocele.

    abstract::This study reports a Chinese family that has suffered from occipital encephalocele over five generations with a pattern of autosomal dominant inheritance. There were 113 family members in this family, and 21 of them had an occipital subscalp encephalocele. The patients with the disease showed normal or nearly normal n...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章

    doi:10.1016/j.clineuro.2006.03.003

    authors: Zhao X,Chi L,Zhao Y,Chi Z

    更新日期:2007-01-01 00:00:00