Repeat surgery for recurrent low-grade gliomas should be standard of care.

Abstract:

:The importance of surgery and maximal extent of resection (EOR) is well established in primary low-grade glioma (LGG) management. However, the role of surgery in the management of recurrent LGG is less clear. A recent review on the management of recurrent LGG concluded there was insufficient evidence to recommend surgery. Here, we summarize the recent advances regarding the role of surgery, radiotherapy (RT) and chemotherapy in the management of recurrent LGG. There is increasing evidence to support maximal EOR for treating recurrent LGG, as it may improve progression free survival (PFS) after recurrence and overall survival (OS). Based on the studies presented in this review, we suggest that repeat surgery with maximal EOR should be standard of care for recurrent LGG treatment.

journal_name

Clin Neurol Neurosurg

authors

Uppstrom TJ,Singh R,Hadjigeorgiou GF,Magge R,Ramakrishna R

doi

10.1016/j.clineuro.2016.09.013

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

18-23

eissn

0303-8467

issn

1872-6968

pii

S0303-8467(16)30344-4

journal_volume

151

pub_type

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