Abstract：
:Macrophages play a central role in determining the host response to tumor, in part through the secretion of several potent products. In this study, our work is directed toward studying the in vitro effects of extract from the larvae of Holotrichia diomphalia (HD-EX) on the ability to induce cellular and secretory responses in mouse peritoneal macrophages. Macrophages were treated with various doses (0.1, 1, 10 microg/ml) of HD-EX for 20 h. This treatment induced tumoricidal activity and increased the production of tumor necrosis factor (TNF-alpha) and nitric oxide (NO) by macrophages in a concentration-dependent manner. However, HD-EX had a little effect on phagocytosis and the levels of hydrogen peroxide (H(2)O(2)), interleukin-1 (IL-1), IL-6 and IL-10 were very low in HD-EX treated macrophages. Thus, the tumoricidal effect of HD-EX appeared to be mainly mediated by NO and TNF-alpha production from macrophages. Taken together, these results suggest that HD-EX is a differential immunomodulating effect on macrophage secretory and cellular activities.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Kang NS,Park SY,Lee KR,Lee SM,Lee BG,Shin DH,Pyo Sdoi
10.1016/s0378-8741(01)00369-5keywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
89-94issue
1eissn
0378-8741issn
1872-7573pii
S0378874101003695journal_volume
79pub_type
杂志文章abstract：ETHNOPHARMACOLOGICAL RELEVANCE:In Traditional Iranian Medicine (TIM), Melissa officinalis L. is commonly regarded as an effective therapy for heart palpitations. OBJECTIVE:Heart palpitation is a common complaint that is often benign and associated with a marked distress that makes the condition difficult to treat. Her...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jep.2015.02.007
更新日期：2015-04-22 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Liuwei Dihuang (LWDH) is a classic prescription that has been used as a traditional medicinal formula for more than 1000 years in China. In clinical, LWDF is used for treating functional decline associated with senile disease and menopausal syndrome. Studies have demonstrated that LWDH co...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2019.112207
更新日期：2020-01-10 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Cydonia oblonga Mill. leaves are traditionally used in Uyghur medicine to treat or prevent cardiovascular disease. Beyond a demonstrated effect on thrombosis, we tested it for an effect on dyslipidemia, in a rat model of hyperlipidemia. METHODS:Seventy healthy Sprague Dawley rats were ra...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.12.010
更新日期：2014-02-03 00:00:00
abstract：AIM OF THE STUDY:Significant pharmacokinetic/pharmacodynamic (PK/PD) interactions between various herbal products and warfarin have recently been reported. The present study was conducted to determine whether Compound Danshen Dripping Pills (CDDP), a Chinese herb medicine used for the treatment of cardiovascular diseas...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2011.08.035
更新日期：2011-10-11 00:00:00
abstract：:In this work we studied in rat the diuretic activity of Opuntia ficus indica (L.) Mill. (Cactaceae) waste matter. The cladodes, flowers and non commerciable fruits were collected in S. Cono (CT, Sicily) cultivation. Acute and chronic diuretic activity of 15% infusion of cladodes, flowers and fruits were assayed. Natri...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(01)00337-3
更新日期：2002-01-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Chuanxiong (Chuanxiong Rhizoma, CR), the dried rhizome of Ligusticum chuanxiong Hort, has been used during pregnancy for more than 2000 years. However, the embryotoxicity of CR was not evaluated so far. The purpose of this study was to examine the safety and rational use of CR during preg...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2019.111895
更新日期：2019-07-15 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Eryngium carlinae F. Delaroche (Apiaceae) is an herb used in folk medicine as a diuretic, analgesic, and anti-inflammatory agent. AIM OF THE STUDY:This work assessed the diuretic, antinociceptive, and anti-inflammatory actions of an ethanol extract from the leaves and stems of Eryngium c...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.113406
更新日期：2021-02-10 00:00:00
abstract：:In the present study, the anti-inflammatory activity of 70% ethanolic extract of Pongamia pinnata leaves (PLE) in acute, subacute and chronic models of inflammation was assessed in rats. Per os (p.o.) administration of PLE (300, 1000 mg/kg) exhibited significant anti-inflammatory activity in acute (carrageenin, histam...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(01)00333-6
更新日期：2001-12-01 00:00:00
abstract：:Pteleopsis suberosa Engl. et Diels was used in the traditional medicine of Mali for the treatment of gastric and duodenal ulcers. In an ethnopharmacological approach, Pteleopsis suberosa extracts of the stem bark were investigated for antiulcer and antibacterial activity against Helicobacter pylori standard strains an...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(97)00109-8
更新日期：1998-01-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:There is very limited information regarding medicinal plants used by traditional healers in Pakistan, for treating wide-ranging diseases. Current study provides significant ethnopharmacological information, both qualitative and quantitative on medical plants in Pakistan and the pharmacolo...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2016.02.039
更新日期：2016-05-26 00:00:00
abstract：:The Indians of the northwest Amazon respect age and try to care for those suffering from senile dementia. At least 25 species of plants are employed in treating Alzheimer's disease or similar problems. The plants are administered orally as teas of the leaves or roots and over a period of several days to numerous weeks...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/0378-8741(93)90007-r
更新日期：1993-03-01 00:00:00
abstract：:This study was undertaken to investigate whether a tea prepared from Syzygium cumini, reported to be used by diabetics in Porto Alegre, Brazil, might have an antihyperglycemic effect in experimental models. Teas prepared from leaves and seeds of S. cumini, in concentrations ranging from 2-64 g/l, were administered, as...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(97)01532-8
更新日期：1997-05-01 00:00:00
abstract：:Aqueous, ethanolic and hexane fractions of Momordica cymbalaria fruits were prepared and given individually at different doses to different batches of rats (both normal and alloxan diabetic rats) after an overnight fast. The blood glucose levels were measured at 0, 1, 3, 5 and 7 h after the treatment. The aqueous extr...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(01)00324-5
更新日期：2001-11-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The ethanolic extract of Lychnophora trichocarpha Spreng. is used in Brazilian folk medicine to treat bruise, pain and inflammatory diseases. AIM OF THE STUDY:The present study aimed at investigating whether ethanolic extract of L. trichocarpha, its ethyl acetate fraction and its main bi...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2012.06.012
更新日期：2012-08-01 00:00:00
abstract：:The hepatoprotective effect of the ethanol/water (1:1) extract of Eclipta alba (Ea) has been studied at subcellular levels in rats against CCl4-induced hepatotoxicity. Ea significantly counteracted CCl4-induced inhibition of the hepatic microsomal drug metabolising enzyme amidopyrine N-demethylase and membrane bound g...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(93)90063-b
更新日期：1993-12-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The area of the "Monte Sicani Regional Park" (Central Western Sicily, southern Italy) has been quantitatively and extensively investigated in an ethnobotanical study for the first time. A total of 108 wild species are used for medicinal purposes, while, according to our study, the uses of...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2014.02.032
更新日期：2014-05-14 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Magnesium lithospermate B (MLB), an active polyphenol acid of Radix Salviae Miltiorrhizae (Danshen), showed a wide range of pharmacological activities in cardiovascular diseases. However, its role in protection against ischemia/reperfusion injury in H9c2 cardiomyocytes has not been elucid...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.11.036
更新日期：2014-01-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Long term hyperglycemia leads to development of complications associated with diabetes. Diabetic complications are now a global health problem without effective therapeutic approach. Hyperglycemia and oxidative stress are important components for the development of diabetic complications....
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2013.08.051
更新日期：2013-10-28 00:00:00
abstract：:This study was designed to determine the anti-proliferative, apoptotic properties of a novel polysaccharide from the loach, Misgurnus anguillicaudatus (MAP), using a human promyelocytic leukemia line (HL-60) as a model system. HL-60 cells were cultured in the presence of MAP at various concentrations (50-800 mg/l) for...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2005.02.033
更新日期：2005-07-14 00:00:00
abstract：ETHNOPHARMOCOLOGICAL RELEVANCE:Terminalia catappa Linn (Combretaceae) is a medicinal plant with anti-inflammatory, anti-diarrhoeal and antioxidant properties, frequently found in tropical regions. Considering its characteristics, it could be useful for the treatment of inflammatory bowel disease, which is associated wi...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2016.07.056
更新日期：2016-11-04 00:00:00
abstract：:The hypoglycemic activity of the flavonoids rich fraction of 70% alcohol extract of the Egyptian Morus alba root bark (MRBF-3) was evaluated after its oral administration to streptozotocin-induced diabetic rats. Diabetes was induced by injection of 60 mg kg(-1) i.p. The administration of MRBF-3 to streptozotocin (STZ)...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2005.03.013
更新日期：2005-09-14 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Traditional herbal medicine has become an important issue on the global scale during the past decade. Among drugs of natural origin, special place belongs to essential oils, known as strong antimicrobial agents that can be used to combat antibiotic-resistant bacteria. Eucalyptus camaldule...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2015.12.008
更新日期：2016-02-03 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Antimicrobial drug resistance is a growing threat to global public health. Historical records and herbal texts relating to traditional Celtic medicine indicate an extensive pharmacopeia of plants for treating infections likely caused by microbes. However, a major barrier for successful in...
journal_title：Journal of ethnopharmacology
pub_type： 历史文章,杂志文章
doi：10.1016/j.jep.2017.03.039
更新日期：2017-05-05 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:This study aims to record and conserve oral traditional knowledge of medicinal plants from the indigenous people living in the western plain region of North Jeolla Province, Korea. MATERIALS AND METHODS:Our research team interviewed 46 key informants (20 men and 26 women) who have lived ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2011.05.001
更新日期：2011-09-01 00:00:00
abstract：:An ethnobotanical study was carried out in six villages in the Bunda district, Mara Region, Tanzania, where the use of plants still has a special meaning to the society, in the treatment of various diseases. Information was obtained from the traditional healers and other experienced persons, having some knowledge on m...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2007.07.006
更新日期：2007-09-25 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Sambucus ebulus L. (S. ebulus) has had long-standing application in Traditional Persian Medicine for joint pain and for a variety of bone and joint disorders. According to traditional use of S. ebulus and its relevant pharmacologic properties, this study was designed to evaluate the effic...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jep.2016.04.035
更新日期：2016-07-21 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Spatholobus suberectus Dunn is a traditional Chinese medicine (TCM) that can activate blood, dispel stasis, inhibit platelet aggregation, and stimulate hematopoiesis, and thereby treat anemia and diseases related to blood stasis syndrome (BSS). However, its hematopoiesis-stimulating activ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2019.111938
更新日期：2019-08-10 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The Kuki-Chin is a composite ethnolinguistic group made up of many distinct groups and subgroups that are linked by a common history, culture, and population distribution in the Kuki-Chin region, shared geopolitically by Bangladesh, India, and Myanmar. This region is shown to be in a hots...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2019.112415
更新日期：2020-04-06 00:00:00
abstract：:As the Mycobacterium tuberculosis strains resistant to multiple drugs are increasing at an alarming rate, there is an urgent need for alternative anti-tuberculosis drugs. In a bioassay-guided search for antimycobacterial compounds obtained from higher plants, the study of the hexane extract from the aerial parts of La...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2006.11.033
更新日期：2007-05-04 00:00:00
abstract：AIM OF THE STUDY:Scutellaria barbata is a traditional Chinese medicine for cancer treatments. Pheophorbide-a (Pa), one of the active components isolated from this herbal medicine has been proposed to be a potential natural photosensitizer for photodynamic therapy. The anti-tumor effect of pheophorbide-a based photodyna...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2010.06.007
更新日期：2010-08-19 00:00:00
