Breakdown of Fermi-liquid theory in a copper-oxide superconductor.

abstract：:Although parasite-host co-speciation is a long-held hypothesis, convincing evidence for long-term co-speciation remains elusive, largely because of small numbers of hosts and parasites studied and uncertainty over rates of evolutionary change. Co-speciation is especially rare in RNA viruses, in which cross-species tra...

journal_title：Nature

authors： Switzer WM,Salemi M,Shanmugam V,Gao F,Cong ME,Kuiken C,Bhullar V,Beer BE,Vallet D,Gautier-Hion A,Tooze Z,Villinger F,Holmes EC,Heneine W

更新日期：2005-03-17 00:00:00

abstract：:The Rho-family GTPase, Cdc42, can regulate the actin cytoskeleton through activation of Wiskott-Aldrich syndrome protein (WASP) family members. Activation relieves an autoinhibitory contact between the GTPase-binding domain and the carboxy-terminal region of WASP proteins. Here we report the autoinhibited structure of...

journal_title：Nature

authors： Kim AS,Kakalis LT,Abdul-Manan N,Liu GA,Rosen MK

更新日期：2000-03-09 00:00:00

abstract：:Grid cells in the entorhinal cortex of freely moving rats provide a strikingly periodic representation of self-location which is indicative of very specific computational mechanisms. However, the existence of grid cells in humans and their distribution throughout the brain are unknown. Here we show that the preferred ...

journal_title：Nature

authors： Doeller CF,Barry C,Burgess N

更新日期：2010-02-04 00:00:00

abstract：:Atrial extracts contain factors which induce potent natriuresis changes in renal haemodynamics, and relax pre-contracted vascular smooth muscle. Low-molecular-weight peptides which mimic these actions have now been purified by several groups, including ours (see accompanying paper), and higher-molecular-weight protein...

journal_title：Nature

authors： Yamanaka M,Greenberg B,Johnson L,Seilhamer J,Brewer M,Friedemann T,Miller J,Atlas S,Laragh J,Lewicki J

更新日期：1984-06-21 00:00:00

abstract：:A long-standing hypothesis posits that natural selection can favour two female strategies when density cycles. At low density, females producing many smaller progeny are favoured when the intrinsic rate of increase, r, governs population growth. At peak density, females producing fewer, high-quality, progeny are favou...

journal_title：Nature

authors： Sinervo B,Svensson E,Comendant T

更新日期：2000-08-31 00:00:00

abstract：:The hydrosulphide ion (HS(-)) and its undissociated form, hydrogen sulphide (H(2)S), which are believed to have been critical to the origin of life on Earth, remain important in physiology and cellular signalling. As a major metabolite in anaerobic bacterial growth, hydrogen sulphide is a product of both assimilatory ...

journal_title：Nature

authors： Czyzewski BK,Wang DN

更新日期：2012-03-11 00:00:00

abstract：:A popular metaphor for the representation of numbers in the brain is the 'mental number line', in which numbers are represented in a continuous, quantity-based analogical format. Here we show that patients with hemispatial neglect misplace the midpoint of a numerical interval when asked to bisect it (for example, stat...

journal_title：Nature

authors： Zorzi M,Priftis K,Umiltà C

更新日期：2002-05-09 00:00:00

abstract：:Positron emission tomography (PET) measurements of brain blood flow were used to monitor changes in the human primary and secondary somatosensory cortices during the period when somatosensory stimuli were expected. In anticipation of either focal or innocuous touching, or localized, painful shocks, blood flow decrease...

journal_title：Nature

authors： Drevets WC,Burton H,Videen TO,Snyder AZ,Simpson JR Jr,Raichle ME

更新日期：1995-01-19 00:00:00

abstract：:The Borrmann effect-a dramatic increase in transparency to X-ray beams-is observed when X-rays satisfying Bragg's law diffract through a perfect crystal. The minimization of absorption seen in the Borrmann effect has been explained by noting that the electric field of the X-ray beam approaches zero amplitude at the cr...

journal_title：Nature

authors： Pettifer RF,Collins SP,Laundy D

更新日期：2008-07-10 00:00:00

abstract：:Aquaporin (AQP) water-channel proteins are freely permeated by water but not by ions or charged solutes. Although mammalian aquaporins were believed to be located in plasma membranes, rat AQP6 is restricted to intracellular vesicles in renal epithelia. Here we show that AQP6 is functionally distinct from other known a...

journal_title：Nature

authors： Yasui M,Hazama A,Kwon TH,Nielsen S,Guggino WB,Agre P

更新日期：1999-11-11 00:00:00

abstract：:Superantigens bind class II major histocompatibility proteins and stimulate powerful proliferative responses of T lymphocytes bearing particular V beta sequences as part of their alpha beta antigen receptor. Exogenous bacterial superantigens are responsible for food poisoning and toxic shock syndrome. Murine virus-enc...

journal_title：Nature

authors： Lafon M,Lafage M,Martinez-Arends A,Ramirez R,Vuillier F,Charron D,Lotteau V,Scott-Algara D

更新日期：1992-08-06 00:00:00

abstract：:The ability to process microbial antigens and present them at the surface of cells is an important aspect of our innate ability to clear infections. It is generally accepted that antigens in the cytoplasm are loaded in the endoplasmic reticulum and presented at the cell surface on major histocompatibility complex (MHC...

journal_title：Nature

authors： Houde M,Bertholet S,Gagnon E,Brunet S,Goyette G,Laplante A,Princiotta MF,Thibault P,Sacks D,Desjardins M

更新日期：2003-09-25 00:00:00

abstract：:Maize smut caused by the fungus Ustilago maydis is a widespread disease characterized by the development of large plant tumours. U. maydis is a biotrophic pathogen that requires living plant tissue for its development and establishes an intimate interaction zone between fungal hyphae and the plant plasma membrane. U. ...

journal_title：Nature

authors： Djamei A,Schipper K,Rabe F,Ghosh A,Vincon V,Kahnt J,Osorio S,Tohge T,Fernie AR,Feussner I,Feussner K,Meinicke P,Stierhof YD,Schwarz H,Macek B,Mann M,Kahmann R

更新日期：2011-10-05 00:00:00

abstract：:The histocompatibility-Y (H-Y) antigen is a minor histocompatibility antigen which has been detected on cell surfaces from the heterogametic sexes of mammalian, bird, amphibian, teleost and invertebrate species. H-Y is thought to be a male-determining substance in mammals because of its almost perfect correlation with...

journal_title：Nature

authors： Shapiro M,Erickson RP

更新日期：1981-04-09 00:00:00

abstract：:Wolbachia is a common maternally inherited bacterial symbiont able to induce crossing sterilities known as cytoplasmic incompatibility (CI) in insects. Wolbachia-modified sperm are unable to complete fertilization of uninfected ova, but a rescue function allows infected eggs to develop normally. By providing a reprodu...

journal_title：Nature

authors： Sinkins SP,Walker T,Lynd AR,Steven AR,Makepeace BL,Godfray HC,Parkhill J

更新日期：2005-07-14 00:00:00

abstract：:Retinal nerve fibres form an orderly map of visual space in several centres in the vertebrate brain. Such topographic maps are a common feature of central nervous system organization, yet the way in which they develop is poorly understood. Early nerve projections in the fetal and neonatal mammalian brain have been fou...

journal_title：Nature

authors： Holt CE,Harris WA

更新日期：1983-01-13 00:00:00

abstract：:A significant portion of prebiotic organic matter on the early Earth may have been introduced by carbonaceous asteroids and comets. The distribution and stable-isotope composition of individual organic compounds in carbonaceous meteorites, which are thought to be derived from asteroidal parent bodies, may therefore pr...

journal_title：Nature

authors： Engel MH,Macko SA,Silfer JA

更新日期：1990-11-01 00:00:00

abstract：:Alternative splicing of pre-messenger RNAs diversifies gene products in eukaryotes and is guided by factors that enable spliceosomes to recognize particular splice sites. Here we report that alternative splicing of Saccharomyces cerevisiae SRC1 pre-mRNA is promoted by the conserved ubiquitin-like protein Hub1. Structu...

journal_title：Nature

authors： Mishra SK,Ammon T,Popowicz GM,Krajewski M,Nagel RJ,Ares M Jr,Holak TA,Jentsch S

更新日期：2011-05-25 00:00:00

abstract：:Drosophila thoracic mechanosensory bristles originate from cells that are singled out from 'proneural' groups of competent epithelial cells. Neural competence is restricted to individual sensory organ precursors (SOPs) by Delta/Notch-mediated 'lateral inhibition', whereas other cells in the proneural field adopt an ep...

journal_title：Nature

authors： De Joussineau C,Soulé J,Martin M,Anguille C,Montcourrier P,Alexandre D

更新日期：2003-12-04 00:00:00

abstract：:Osteoarthritis-the most common form of age-related degenerative whole-joint disease1-is primarily characterized by cartilage destruction, as well as by synovial inflammation, osteophyte formation and subchondral bone remodelling2,3. However, the molecular mechanisms that underlie the pathogenesis of osteoarthritis are...

journal_title：Nature

authors： Choi WS,Lee G,Song WH,Koh JT,Yang J,Kwak JS,Kim HE,Kim SK,Son YO,Nam H,Jin I,Park ZY,Kim J,Park IY,Hong JI,Kim HA,Chun CH,Ryu JH,Chun JS

更新日期：2019-02-01 00:00:00

abstract：:The tumour-suppressor gene p53 is frequently mutated in human cancers and is important in the cellular response to DNA damage. Although the p53 family members p63 and p73 are structurally related to p53, they have not been directly linked to tumour suppression, although they have been implicated in apoptosis. Given th...

journal_title：Nature

authors： Flores ER,Tsai KY,Crowley D,Sengupta S,Yang A,McKeon F,Jacks T

更新日期：2002-04-04 00:00:00

abstract：:Multiplicative operations are important in sensory processing, but their biophysical implementation remains largely unknown. We investigated an identified neuron (the lobula giant movement detector, LGMD, of locusts) whose output firing rate in response to looming visual stimuli has been described by two models, one o...

journal_title：Nature

authors： Gabbiani F,Krapp HG,Koch C,Laurent G

更新日期：2002-11-21 00:00:00

abstract：:When a spatially uniform temperature change is imposed on a solid with more than one phase, or on a polycrystal of a single, non-cubic phase (showing anisotropic expansion-contraction), the resulting thermal strain is inhomogeneous (non-affine). Thermal cycling induces internal stresses, leading to structural and prop...

journal_title：Nature

authors： Ketov SV,Sun YH,Nachum S,Lu Z,Checchi A,Beraldin AR,Bai HY,Wang WH,Louzguine-Luzgin DV,Carpenter MA,Greer AL

更新日期：2015-08-13 00:00:00

abstract：:The Earth's mantle is isotopically heterogeneous on length scales ranging from centimetres to more than 10(4) kilometres. This heterogeneity originates from partial melt extraction and plate tectonic recycling, whereas stirring during mantle convection tends to reduce it. Here we show that mid-ocean ridge basalts from...

journal_title：Nature

authors： Graham DW,Blichert-Toft J,Russo CJ,Rubin KH,Albarède F

更新日期：2006-03-09 00:00:00

abstract：:Several distinct cell lineages are established during mouse embryogenesis. The trophectoderm and primitive endoderm give rise to extraembryonic structures alone, while the primitive ectoderm becomes the fetus proper. Recent studies suggest that the levels of DNA modification are lower in inactive X chromosomes from ex...

journal_title：Nature

authors： Chapman V,Forrester L,Sanford J,Hastie N,Rossant J

更新日期：1984-01-19 00:00:00

abstract：:Photoinduced electron transfer (PET) is a phenomenon whereby the absorption of light by a chemical species provides an energetic driving force for an electron-transfer reaction1-4. This mechanism is relevant in many areas of chemistry, including the study of natural and artificial photosynthesis, photovoltaics and pho...

journal_title：Nature

authors： MacKenzie IA,Wang L,Onuska NPR,Williams OF,Begam K,Moran AM,Dunietz BD,Nicewicz DA

更新日期：2020-04-01 00:00:00

abstract：:Polycomb group proteins have an essential role in the epigenetic maintenance of repressive chromatin states. The gene-silencing activity of the Polycomb repressive complex 2 (PRC2) depends on its ability to trimethylate lysine 27 of histone H3 (H3K27) by the catalytic SET domain of the EZH2 subunit, and at least two o...

journal_title：Nature

authors： Margueron R,Justin N,Ohno K,Sharpe ML,Son J,Drury WJ 3rd,Voigt P,Martin SR,Taylor WR,De Marco V,Pirrotta V,Reinberg D,Gamblin SJ

更新日期：2009-10-08 00:00:00

abstract：:Memory formation is a multi-stage process that initially requires cellular consolidation in the hippocampus, after which memories are downloaded to the cortex for maintenance, in a process termed systems consolidation. Epigenetic mechanisms regulate both types of consolidation, but histone variant exchange, in which c...

journal_title：Nature

authors： Zovkic IB,Paulukaitis BS,Day JJ,Etikala DM,Sweatt JD

更新日期：2014-11-27 00:00:00

abstract：:Insect eyes have an anti-reflective coating, owing to nanostructures on the corneal surface creating a gradient of refractive index between that of air and that of the lens material1,2. These nanocoatings have also been shown to provide anti-adhesive functionality3. The morphology of corneal nanocoatings are very dive...

journal_title：Nature

authors： Kryuchkov M,Bilousov O,Lehmann J,Fiebig M,Katanaev VL

更新日期：2020-09-01 00:00:00

abstract：:Evolution of the earliest mammals shows successive episodes of diversification. Lineage-splitting in Mesozoic mammals is coupled with many independent evolutionary experiments and ecological specializations. Classic scenarios of mammalian morphological evolution tend to posit an orderly acquisition of key evolutionary...

journal_title：Nature

authors： Luo ZX

更新日期：2007-12-13 00:00:00