Abstract：
:Patients with early-stage non-small-cell lung cancer (NSCLC) should be treated with complete surgical resection whenever possible. Incomplete resections do not cure, and the optimal pulmonary resection is anatomic lobectomy. Limited resections (wedge resection and segmentectomy) are associated with a threefold increase in local recurrence, which translates into decreased survival. The addition of mediastinal lymph node dissection produces the best pathologic staging but has never been shown to improve survival. Resections can be performed through a variety of incisions and even using minimally invasive techniques, but posterolateral thoracotomy seems to provide the best exposure and is used most frequently. Adjuvant radiotherapy in both the preoperative and postoperative settings does not improve survival in patients with resected NSCLC. Similarly, postoperative chemotherapy cannot be advocated in these patients based on the current data. Improved survival has been demonstrated in the randomized setting for patients with locally advanced, resectable disease (N2) using preoperative (induction) chemo(radio)therapy, but the numbers are small. Patients with this stage of NSCLC should be enrolled in induction therapy protocols whenever possible to confirm the efficacy of this approach.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Korst RJ,Ginsberg RJdoi
10.1007/s002680020017keywords:
subject
Has Abstractpub_date
2001-02-01 00:00:00pages
184-8issue
2eissn
0364-2313issn
1432-2323journal_volume
25pub_type
杂志文章,评审abstract：:Endoscopic sphincterotomy (EST) is an established method for treatment of retained or recurrent common bile duct (CBD) calculi after cholecystectomy. Present experience shows that few patients have recurrent biliary tract complications, but follow-up periods are most often short. EST was performed in 147 patients with...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900043
更新日期：1996-03-01 00:00:00
abstract：:The safe and permissible limits of hepatectomy in obstructive jaundice patients and the usefulness of preoperative portal embolization (PE) for increasing the limit for safe hepatectomy were examined. We classified 416 patients with hepatectomy performed over 9 years under the following headings: normal liver function...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7128-7
更新日期：2004-05-01 00:00:00
abstract：:Necrotizing lesions of the soft tissues are grave entities not infrequently seen in daily surgical practice. They may occur with epidemic proportions after natural disasters, representing a serious challenge to the surgeon since they are characteristically associated with high mortality rates unless an early diagnosis...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01659058
更新日期：1991-03-01 00:00:00
abstract：:The surgical morbidity, mortality, and effectiveness of a modified nonshunting operation that includes splenic artery division instead of splenectomy, devascularization, and esophageal transection (SAD group) were evaluated. Eighteen cirrhotic patients with varices who underwent this modified procedure were compared w...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00299180
更新日期：1995-05-01 00:00:00
abstract：BACKGROUND:Resection of hepatocellular carcinoma (HCC) located in the right liver often requires hepatic mobilization. However, exposure of the HCC may be restricted when using the conventional abdominal approach (AA). In such cases, a thoracoabdominal approach (TA) can provide a good operating field. Although several ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1023-9
更新日期：2011-05-01 00:00:00
abstract：:The post-Soviet calamities of East European cardiac surgery highlight the spectrum of marked differences in overall operative capacities among individual post-Communist countries. A comparison with the level of cardiac surgery in Western Europe reveals the importance of continuing relief, comprising both educational a...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7103-8
更新日期：2003-08-01 00:00:00
abstract：:The evaluation of screening programs for cancer is considered. Initial evaluation has to be in terms of mortality, but increasing importance should be attached to measures which evaluate the interaction of early detection with the disease process. These include the degree to which diagnosis is advanced, both in time a...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01671147
更新日期：1989-01-01 00:00:00
abstract：:Since the pathogenesis of endocrine ophthalmopathy is unclear, there has been little agreement on the treatment of the disease. The influence of thyroid surgery on endocrine ophthalmopathy is controversial. To evaluate the effect of thyroid surgery on the course of the disease, we developed a special ophthalmopathy in...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01658552
更新日期：1990-05-01 00:00:00
abstract：BACKGROUND:A recent analysis found bradycardia during laparoscopy as a potential early warning sign of cardiac arrest. Knowledge regarding bradycardia frequency and its consequences during laparoscopy is limited. METHODS:Using the computerized record database, files of 9915 patients undergoing laparoscopic surgery, be...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-04935-x
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Intra-abdominal adhesions constitute between 49% and 74% of the causes of small bowel obstruction. Traditionally, laparotomy and open adhesiolysis have been the treatment for patients who have failed conservative measures or when clinical and physiologic derangements suggest toxemia and/or ischemia. With the...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-7778-0
更新日期：2006-04-01 00:00:00
abstract：:Two-hundred and fifty patients undergoing initial exploration for primary hyperparathyroidism were analyzed for differences in clinical presentation, biochemical status, pathology, and outcome of surgery. In patients less than 60 years of age (younger patients, n = 119) the most common preoperative symptoms and signs ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF02067389
更新日期：1992-07-01 00:00:00
abstract：INTRODUCTION:Despite formal definitions of mucinous cystic neoplasms (MCNs) and intraductal papillary neoplasms (IPMNs) by the World Health Organization (WHO) and Armed Forces Institute of Pathology (AFIP), several controversies with regard to MCNs remain. The aim of this review was to determine the clinicopathological...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-006-0126-1
更新日期：2006-12-01 00:00:00
abstract：:Leiomyomas and leiomyosarcomas are derived from smooth muscle tissues. Smooth muscle cells also surround the blood vessels that supply the alimentary tract. These cells have at times been said to contribute to the formation of smooth muscle tumors in the alimentary canal. With such an abundance of smooth muscle, there...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689910063
更新日期：2000-04-01 00:00:00
abstract：BACKGROUND:Screening of multiple endocrine neoplasia type 1 (MEN-1) patients is widely recommended because one-fifth succumb to malignant neoplasms. However, recommendations for screening modalities and intervals are based mostly on nonprospective data. METHODS:Thirty-five of 48 MEN-1 patients were evaluated at least ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-9983-8
更新日期：2009-06-01 00:00:00
abstract：:This prospective study addresses the rate of male genital dysfunction following total mesorectal excision (TME) for rectal carcinoma using the anterior extramesorectal plane and its correlation with early urinary function, pelvic autonomic nerve preservation (PANP), and intraoperative neurostimulation (INS). A consecu...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9008-4
更新日期：2007-06-01 00:00:00
abstract：BACKGROUND:Macroscopic extrathyroidal extension (ETE) is a poor prognostic factor in papillary thyroid carcinoma (PTC). However, intraoperative inspection for ETE is often inaccurate and could lead the surgeon to misconstrue simple adhesion as gross ETE. Such confusion could result in more aggressive treatment than nec...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2034-5
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:Many patients who undergo emergency laparotomy are working, which is a key determinant for an individual's socio-economic status and financial security. The objectives of this study were to compare labour market participation and sick leave in a nationwide patient population undergoing non-malignant emergenc...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4830-4
更新日期：2019-03-01 00:00:00
abstract：AIMS:Post-operative urinary retention (POUR) is a common cause of unplanned admission following day-case surgery and has negative effects on both patient and surgical institution. We aimed to prospectively evaluate potential risk factors for the development of POUR following day-case general surgical procedures. METHO...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4697-4
更新日期：2018-12-01 00:00:00
abstract：:Jejunostomy is a surgical procedure by which a tube is situated in the lumen of the proximal jejunum, primarily to administer nutrition. There are many techniques used for jejunostomy: longitudinal Witzel, transverse Witzel, open gastrojejunostomy, needle catheter technique, percutaneous endoscopy, and laparoscopy. Th...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/pl00012353
更新日期：1999-06-01 00:00:00
abstract：BACKGROUND:Uncomplicated acute appendicitis has been managed traditionally by early appendicectomy. However, recently, there has been increasing interest in the potential for primary treatment with antibiotics, with studies finding this to be associated with fewer complications than appendicectomy. The aim of this stud...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析
doi：10.1007/s00268-016-3561-7
更新日期：2016-10-01 00:00:00
abstract：:We determined the relative value of the metastatic colorectal cancer doubling time as a predictor of recurrence and survival after hepatectomy in comparison with other established predictors. Consecutive patients who underwent hepatic resection ( n = 144) for colorectal cancer liver metastases were studied retrospecti...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7088-3
更新日期：2004-03-01 00:00:00
abstract：BACKGROUND:The technical complexity of pancreatic resection has made it a specialized procedure performed in high-volume centers. It has been shown that patients operated on in high-volume pancreatobiliary centers have fewer complications and better survival. The purpose of this study was to share our experience with a...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2644-6
更新日期：2014-10-01 00:00:00
abstract：:A large number of families with familial isolated hyperparathyroidism (FIHP) have been reported. We wanted to determine if some of these families represent early manifestations of full-blown syndromes such as multiple endocrine neoplasia type 1 (MEN-1), as early identification may alter surgical and medical management...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6617-9
更新日期：2002-08-01 00:00:00
abstract：BACKGROUND:Chagas disease is a serious public health issue in South and Central America due to its high prevalence, morbidity, and mortality. The esophageal form of the disease leads to achalasia and consequent megaesophagus. In advanced or recurrent cases of megaesophagus, there is no consensus for which of three esta...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2445-3
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:Organ shortage is the greatest challenge facing the field of organ transplantation today. Use of more organs of marginal quality has been advocated to address the shortage. METHOD:We examined the pattern of donation and organ use in the United States as shown in the Organ Procurement and Transplantation Net...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1748-0
更新日期：2012-12-01 00:00:00
abstract：INTRODUCTION:Gastroesophageal reflux disease (GERD) may present with heartburn, regurgitation, dysphagia, chronic cough, laryngitis, or even asthma. The clinical presentation of GERD is therefore varied and poses certain challenges to the physician, especially given the limitations of the diagnostic testing. DISCUSSIO...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-017-3953-3
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND:Intestinal epithelial cell apoptosis has been reported in sepsis as a mechanism of organ failure. The aim of this study was to clarify the role of apoptosis-regulating proteins (bcl-2, bax, cytochrome-c, and caspase-8) in septic rats by studying their expression in gastric and intestinal epithelial cells. M...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0742-1
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND:This prospective, non-randomized, comparative study evaluated morbidity of chemotherapy administration via a totally implantable venous access device (TIVAD) versus peripheral intravenous access (PIVA), and satisfaction in breast cancer patients in a limited-resource setting. METHODS:Consecutive patients re...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2378-x
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:The skin is closed in open appendectomy traditionally with few interrupted nonabsorbable sutures. The use of this old method is based on a suggestion that this technique decreases wound infections. In pediatric surgery, skin closure with running intradermal absorbable sutures has been found to be as safe as ...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-012-1664-3
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:Thymic epithelial tumors are characterized by slow growth and variable malignant behavior. We present our experience on the surgical management of these tumors. MATERIALS AND METHODS:We conducted a retrospective analysis of patients with thymomas undergoing modified maximal thymectomy over a period of 16 ye...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0097-0
更新日期：2009-08-01 00:00:00
