Computed tomographic angiography findings in 103 patients following vascular events in the posterior circulation: potential and clinical relevance.

Abstract:

:We studied the diagnostic value of computed tomographic angiography (CTA) in the posterior circulation as a noninvasive substitute for intra-arterial digital subtraction angiography (DSA). We prospectively investigated 103 patients with acute stroke in the posterior circulation. All patients underwent CTA and Doppler ultrasound, and DSA was performed in 22 patients. Vascular findings were classified in categories according to the type of lesion and the location in the vertebral, basilar, or posterior cerebral artery. In the first part of the analysis we examined the correlation between CTA and intra-arterial DSA (n=22), and in the second part that between CTA and Doppler ultrasound (n=103). Intra-arterial DSA identified 11 stenoses, 13 occlusions, and 3 hypoplasias. The correlation between DSA and CTA was best for the basilar artery (all lesions were identified with CTA). Of the 14 lesions detected in the vertebral artery by DSA 13 were also detected by CTA, but the specific type of lesion was identified in only 7 cases. The correlation between CTA and Doppler ultrasound was lower. In conclusion, CTA is thus a reliable method for detecting lesions in the posterior circulation and may replace DSA in many cases. However, particularly in the vertebral artery DSA remains the superior technique.

journal_name

J Neurol

journal_title

Journal of neurology

authors

Graf J,Skutta B,Kuhn FP,Ferbert A

doi

10.1007/s004150070089

keywords:

subject

Has Abstract

pub_date

2000-10-01 00:00:00

pages

760-6

issue

10

eissn

0340-5354

issn

1432-1459

journal_volume

247

pub_type

临床试验,杂志文章
  • Cerebral angiitis mimicking posterior leukoencephalopathy.

    abstract::Posterior leukoencephalopathy typically denotes neurotoxicity from immunosuppressive agents, malignant hypertension or eclampsia. It has not been documented in central nervous system angiitis. We present three cases associated with isolated cerebral angiitis after review of all cases of isolated CNS angiitis from 1998...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-003-1021-4

    authors: Wijdicks EF,Manno EM,Fulgham JR,Giannini C

    更新日期:2003-04-01 00:00:00

  • Botulinum toxin in multiple sclerosis.

    abstract::Local administration of botulinum toxin (BoTx) inhibits presynaptic acetylcholine release. All cholinergically innervated muscles and glands can be paralyzed accordingly. Studies on the application of BoTx in multiple sclerosis have shown good results for focal spasticity, in particular, of the extremities. The first ...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-006-1104-0

    authors: Jost WH

    更新日期:2006-02-01 00:00:00

  • Clinical feasibility of 1-min ultrafast brain MRI compared with routine brain MRI using synthetic MRI: a single center pilot study.

    abstract:BACKGROUND:Ultrafast brain MRI is required for uncooperative patients and time-critical diseases such as stroke because it reduces scan times and motion artifacts. This study investigated the clinical feasibility of a 1-min ultrafast brain MRI protocol for detecting intracranial abnormalities in restless and uncooperat...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-018-9149-4

    authors: Ryu KH,Choi DS,Baek HJ,Cho SB,Ha JY,Kim TB,Hwang MJ

    更新日期:2019-02-01 00:00:00

  • Aspirin plus clopidogrel may reduce the risk of early neurologic deterioration in ischemic stroke patients carrying CYP2C19*2 reduced-function alleles.

    abstract:OBJECTIVES:The mechanisms of early neurologic deterioration (END) and prevention strategies for END are not completely understood. The aim of this study was to investigate the association between CYP2C19*2 variants and END, and the effectiveness of antiplatelet therapy for prevention of END according to CYP2C19*2 genot...

    journal_title:Journal of neurology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s00415-018-8998-1

    authors: Yi X,Zhou Q,Wang C,Lin J,Chai Z

    更新日期:2018-10-01 00:00:00

  • Double-blind study of the activity and tolerability of cabergoline versus placebo in parkinsonians with motor fluctuations.

    abstract::The use of a dopamine agonist with a long duration of action has theoretical advantages in attempting to reduce the motor fluctuations in Parkinson's disease. We report the results of a double-blind controlled study of adding cabergoline, an ergot derivative with potent long-lasting high affinity for the D2 receptor, ...

    journal_title:Journal of neurology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF00878534

    authors: Steiger MJ,El-Debas T,Anderson T,Findley LJ,Marsden CD

    更新日期:1996-01-01 00:00:00

  • Transcranial magnetic stimulation: specific and non-specific facilitation of magnetic motor evoked potentials.

    abstract::Different physiological mechanisms of facilitation of latencies and amplitudes of magnetic motor evoked potentials (MEPs) were evaluated in a cohort of 140 healthy volunteers. The potentials were induced at the vertex and recorded at the abductor pollicis brevis. The aim of the present investigation was to compare phy...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00314732

    authors: Hufnagel A,Jaeger M,Elger CE

    更新日期:1990-11-01 00:00:00

  • Olfactory testing does not predict β-amyloid, MRI measures of neurodegeneration or vascular pathology in the British 1946 birth cohort.

    abstract:OBJECTIVE:To explore the value of olfactory identification deficits as a predictor of cerebral β-amyloid status and other markers of brain health in cognitively normal adults aged ~ 70 years. METHODS:Cross-sectional observational cohort study. 389 largely healthy and cognitively normal older adults were recruited from...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-020-10004-4

    authors: Buchanan SM,Parker TD,Lane CA,Keshavan A,Keuss SE,Lu K,James SN,Murray-Smith H,Wong A,Nicholas J,Cash DM,Malone IB,Coath W,Thomas DL,Sudre C,Fox NC,Richards M,Schott JM

    更新日期:2020-11-01 00:00:00

  • Non-motor multiple system atrophy associated with sudden death: pathological observations of autonomic nuclei.

    abstract::Multiple system atrophy (MSA) manifests as a combination of dysautonomia and motor symptoms/signs. However, rare cases presenting with autonomic failures in absence of motor symptoms/signs until their deaths have been reported and are referred to as non-motor MSA. To clarify pathological findings underlying non-motor ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-017-8604-y

    authors: Riku Y,Watanabe H,Mimuro M,Iwasaki Y,Ito M,Katsuno M,Sobue G,Yoshida M

    更新日期:2017-11-01 00:00:00

  • Cerebrovascular hemodynamic changes in multiple sclerosis patients during head-up tilt table test: effect of high-dose intravenous steroid treatment.

    abstract::Demyelination in multiple sclerosis (MS) may cause damage to the vegetative nervous system. Our objective was to examine cerebral autoregulation assessed via blood pressure and cerebral blood flow velocity fluctuations during head-up tilt table testing. We also investigated the effects of high-dose intravenous cortico...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-013-6977-0

    authors: Mezei Z,Olah L,Kardos L,Kovacs RK,Csiba L,Csepany T

    更新日期:2013-09-01 00:00:00

  • [Peripheral nerve compression by ganglionic cysts (author's transl)].

    abstract::Extra- and intraneural ganglionic cysts rarely involved peripheral nerves. They are found in the neighbourhood of large joints. Intraneural cysts prefer the deep peroneal nerve and cause intermittent pain and severe nerve damage. The ulnar nerve is affected most often at the wrist. There are different types of distal ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00314606

    authors: Assmus H,Kühner A,Hagenlocher U

    更新日期:1975-06-09 00:00:00

  • CBF changes in drug naive juvenile myoclonic epilepsy patients.

    abstract:PURPOSE:The role of thalamus and brainstem in generalized epilepsy has been suggested in previous studies. The aim of the present study was to assess regional cerebral blood flow (rCBF) abnormality in juvenile myoclonic epilepsy (JME) patients. METHODS:(99m)Tc-ethylcysteinate dimer brain single photon emission compute...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-006-0491-6

    authors: Tae WS,Joo EY,Han SJ,Lee KH,Hong SB

    更新日期:2007-08-01 00:00:00

  • Seasonal occurrence of relapses in inflammatory myopathies: a preliminary study.

    abstract::The seasonal occurrence of relapses was analysed retrospectively in a group of 53 patients with treated dermatomyositis (DM) or polymyositis (PM). In DM, the incidence of both myositic and cutaneous relapses was highest in summer whereas in the PM group relapses was more evenly distributed throughout the seasons but l...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s004150200036

    authors: Phillips BA,Zilko PJ,Garlepp MJ,Mastaglia FL

    更新日期:2002-04-01 00:00:00

  • Longitudinal evaluation of quality of life in 288 patients with neurofibromatosis 2.

    abstract::Advances in molecular biology have resulted in novel therapy for neurofibromatosis 2-related (NF2) tumours, highlighting the need for robust outcome measures. The disease-focused NF2 impact on quality of life (NFTI-QOL) patient questionnaire was assessed as an outcome measure for treatment in a multi-centre study. NFT...

    journal_title:Journal of neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00415-014-7303-1

    authors: Ferner RE,Shaw A,Evans DG,McAleer D,Halliday D,Parry A,Raymond FL,Durie-Gair J,Hanemann CO,Hornigold R,Axon P,Golding JF

    更新日期:2014-05-01 00:00:00

  • Progressive multifocal leukoencephalopathy and natalizumab.

    abstract::Natalizumab (TYSABRI(®)), a specific α4-integrin antagonist, is approved as a second-line treatment of relapsing-remitting MS (RRMS) patients who fail therapy with interferons or as first-line treatment of patients with highly active relapsing-remitting disease. Since the market introduction of natalizumab as a monoth...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-011-6116-8

    authors: Hellwig K,Gold R

    更新日期:2011-11-01 00:00:00

  • ANO10 mutations cause ataxia and coenzyme Q₁₀ deficiency.

    abstract::Inherited ataxias are heterogeneous disorders affecting both children and adults, with over 40 different causative genes, making molecular genetic diagnosis challenging. Although recent advances in next-generation sequencing have significantly improved mutation detection, few treatments exist for patients with inherit...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-014-7476-7

    authors: Balreira A,Boczonadi V,Barca E,Pyle A,Bansagi B,Appleton M,Graham C,Hargreaves IP,Rasic VM,Lochmüller H,Griffin H,Taylor RW,Naini A,Chinnery PF,Hirano M,Quinzii CM,Horvath R

    更新日期:2014-11-01 00:00:00

  • Systematic review of the clinical spectrum of CASPR2 antibody syndrome.

    abstract:BACKGROUND:Contactin-associated protein-like 2 (CASPR2) autoantibody disease has a variable clinical phenotype. We present a case report and performed a systematic review of the literature to summarize: (1) the clinical phenotype of patients with CASPR2 antibodies, (2) the findings in neurological investigations, and (...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-019-09686-2

    authors: Boyko M,Au KLK,Casault C,de Robles P,Pfeffer G

    更新日期:2020-04-01 00:00:00

  • Intraventricular haemorrhage, CT and arteriographic findings in thirty-five patients.

    abstract::Thirty-five patients with intraventricular haemorrhage shown by CT underwent cerebral arteriography. In 15 patients arteriography showed an occlusion of a carotid or middle cerebral artery. Secondary bleeding into an infarction caused the intraventricular haemorrhage. All 15 patients were aged over 40 years. ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00313641

    authors: Cohn DF,Avrahami E

    更新日期:1983-01-01 00:00:00

  • MRI findings in Hirayama's disease: flexion-induced cervical myelopathy or intrinsic motor neuron disease?

    abstract::Hirayama's disease is a benign juvenile form of focal amyotrophy affecting the upper limbs. Previous studies have suggested that the disorder is a neck flexion induced cervical myelopathy. We report clinical and magnetic resonance imaging findings in nine patients with Hirayama's disease. Cervical imaging of seven pat...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s004150050514

    authors: Schröder R,Keller E,Flacke S,Schmidt S,Pohl C,Klockgether T,Schlegel U

    更新日期:1999-11-01 00:00:00

  • Hallervorden-Spatz disease: clinical and MRI study of 11 cases diagnosed in life.

    abstract::The diagnosis of Hallervorden-Spatz disease (HSD) has usually been made post mortem, although the recent description of characteristic abnormalities in the globus pallidus has suggested the possibility of an in vivo diagnosis. We present the clinical histories, neurological features and MRI findings of 11 patients, di...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00856805

    authors: Angelini L,Nardocci N,Rumi V,Zorzi C,Strada L,Savoiardo M

    更新日期:1992-10-01 00:00:00

  • News on the genetics, epidemiology, medical care and translational research of Schwannomas.

    abstract::Recent years have seen substantial news and updates in the genetics and diagnosis of schwannomas, even a new hereditary disease with schwannomas; Schwannomatosis has been defined. These developments have consequently led to better evaluation of the incidence of schwannomas. Although there has also been progress in the...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-006-0347-0

    authors: Hanemann CO,Evans DG

    更新日期:2006-12-01 00:00:00

  • Normalized grip strength is a sensitive outcome measure through all stages of Duchenne muscular dystrophy.

    abstract:OBJECTIVE:The main aim was to explore the changes in hand-grip strength in patients with Duchenne muscular dystrophy (DMD) aged 5-29 years. Secondary aims were to test the effect of mutation, ambulatory status and glucocorticoid use on grip strength and its changes over time and to compute the number of subjects needed...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-020-09800-9

    authors: Hogrel JY,Decostre V,Ledoux I,de Antonio M,Niks EH,de Groot I,Straub V,Muntoni F,Ricotti V,Voit T,Seferian A,Gidaro T,Servais L

    更新日期:2020-07-01 00:00:00

  • Admission diagnoses of patients later diagnosed with autoimmune encephalitis.

    abstract:BACKGROUND:Since the detection of autoantibodies against neuronal surface antigens, autoimmune encephalitis (AE) has been more frequently diagnosed, especially in patients with symptoms typical of limbic encephalitis, such as seizures, short-term memory deficits, or psychosis. However, the clinical spectrum of AE may b...

    journal_title:Journal of neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00415-018-9105-3

    authors: Baumgartner A,Rauer S,Hottenrott T,Leypoldt F,Ufer F,Hegen H,Prüss H,Lewerenz J,Deisenhammer F,Stich O

    更新日期:2019-01-01 00:00:00

  • Macro EMG follow-up study in post-poliomyelitis patients.

    abstract::We investigated the muscle strength and motor unit (MU) territory of five patients with postpolio syndrome (PPS), six stable patients with prior poliomyelitis, and five healthy volunteers. The MU territory was assessed by measuring amplitudes of motor unit potentials (MUPs) recorded by the macro EMG technique. The inv...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00920572

    authors: Ivanyi B,Ongerboer de Visser BW,Nelemans PJ,de Visser M

    更新日期:1994-12-01 00:00:00

  • Vestibular animal models: contributions to understanding physiology and disease.

    abstract::Our knowledge of the vestibular sensory system, its functional significance for gaze and posture stabilization, and its capability to ensure accurate spatial orientation perception and spatial navigation has greatly benefitted from experimental approaches using a variety of vertebrate species. This review summarizes t...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-015-7909-y

    authors: Straka H,Zwergal A,Cullen KE

    更新日期:2016-04-01 00:00:00

  • Clinical experience with high-dose idebenone in Friedreich ataxia.

    abstract::Several reports in the literature describe the effects of low-dose (5 mg/kg/day) idebenone in significantly reducing cardiac hypertrophy in patients with Friedreich ataxia. However, the effects of idebenone on neurological function have not been reliably determined in these studies; when neurological parameters were r...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-009-1008-x

    authors: Schulz JB,Di Prospero NA,Fischbeck K

    更新日期:2009-03-01 00:00:00

  • Interplay of cerebral autoregulation and neurovascular coupling evaluated by functional TCD in different orthostatic conditions.

    abstract:BACKGROUND:Adequate cerebral blood flow (CBF) is mainly governed by neurovascular coupling (NC) which adapts local CBF to underlying cortical activity,and cerebral autoregulation (CA)that tends to maintain constant CBF despite changes in arterial blood pressure (BP). Since it was suggested that resistance vessels play ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-006-0338-1

    authors: Azevedo E,Rosengarten B,Santos R,Freitas J,Kaps M

    更新日期:2007-02-01 00:00:00

  • Adrenoleukodystrophy: detection of increased very long chain fatty acids by high-performance liquid chromatography.

    abstract::Using high-performance liquid chromatography, adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN) were diagnosed by the analysis of fatty acids in sphingomyelin. The analytical method was simple, sensitive and accurate. In ALD and AMN patients, very long chain fatty acids (C26:0, C25:0 and C24:0 on the base of ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00313696

    authors: Kobayashi T,Katayama M,Suzuki S,Tomoda H,Goto I,Kuroiwa Y

    更新日期:1983-01-01 00:00:00

  • Decompressive hemicraniectomy in severe cerebral venous thrombosis: a prospective case series.

    abstract::Small retrospective case series suggest that decompressive hemicraniectomy can be life saving in patients with cerebral venous thrombosis (CVT) and impending brain herniation. Prospective studies of consecutive cases are lacking. Thus, a single centre, prospective study was performed. In 2006 we adapted our protocol f...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-011-6307-3

    authors: Zuurbier SM,Coutinho JM,Majoie CB,Coert BA,van den Munckhof P,Stam J

    更新日期:2012-06-01 00:00:00

  • Internuclear ophthalmoplegia plus ataxia indicates a dorsomedial tegmental lesion at the pontomesencephalic junction.

    abstract::Internuclear ophthalmoplegia (INO) indicates a lesion involving the medial longitudinal fasciculus (MLF) that interconnects the abducens nucleus and medial rectus subnucleus of the oculomotor nuclear complex. In fact, rostral-caudal localization value of the INO is often limited except when it accompanies symptoms and...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-016-8088-1

    authors: Lee SU,Kim HJ,Park JJ,Kim JS

    更新日期:2016-05-01 00:00:00

  • Epidemics and outbreaks of peripheral nervous system disorders: II. Toxic and nutritional causes.

    abstract::Peripheral neuropathies have various causes, both infectious and non-infectious. When we think of "epidemics", we often refer to an infectious or even post-infectious origin. Nevertheless, the history of mankind is marked by episodes of epidemics of peripheral neuropathies of non-infectious nature, either of nutrition...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-020-10216-8

    authors: Mathis S,Soulages A,Vallat JM,Le Masson G

    更新日期:2020-09-11 00:00:00