Abstract：
:In this study we have evaluated the analgesic activity of dry latex (DL) of Calotropis procera. A single oral dose of DL ranging from 165 to 830 mg/kg produced a significant dose dependent analgesic effect against acetic acid induced writhings. The effect of DL at a dose of 415 mg/kg was more pronounced as compared to a 100 mg/kg oral dose of aspirin. On the other hand DL (830 mg/kg) produced marginal analgesia in a tail-flick model which was comparable to aspirin. The analgesic effect of DL was delayed by 1 h by naloxone at a dose of 0. 5 mg/kg, i.p., which completely blocked the analgesic effect of morphine (10 mg/kg, i.p.). However, the effect of aspirin was not blocked by naloxone. The 830 mg/kg oral dose of DL did not produce toxic effects in mice and the LD(50) was found to be 3 g/kg.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Dewan S,Sangraula H,Kumar VLdoi
10.1016/s0378-8741(00)00272-5keywords:
subject
Has Abstractpub_date
2000-11-01 00:00:00pages
307-11issue
1-2eissn
0378-8741issn
1872-7573pii
S0378-8741(00)00272-5journal_volume
73pub_type
杂志文章abstract：:Lyophilised hydroalcoholic and aqueous extracts of the aerial parts of Passiflora incarnata L. (Passifloraceae) (Passion-flower), as well as chemical constituents of the plant, indole alkaloids (harman, harmin, harmalin, harmol, and harmalol) maltol and flavonoids (orientin, isoorientin, vitexin and isovitexin) were a...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(97)00042-1
更新日期：1997-06-01 00:00:00
abstract：AIM OF THE STUDY:Sophora flavescens has been used as an antipyretic and analgesic agent. To assess the possible herb-drug interaction, effects of S. flavescens extracts on hepatic cytochrome P450 (P450, CYP) enzymes were studied. MATERIALS AND METHODS:Effects of the extracts prepared by three different pharmaceutical ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2009.09.018
更新日期：2009-12-10 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Quercus Infectoria galls (QIG) have a long history of use in traditional Chinese medicine and traditional Uyghur medicine for the treatment of diarrhea, hemorrhage, skin disease, and many other human ailments. Medicinal applications of QIG have become increasingly popular in Greece, Asia ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2020.113592
更新日期：2020-11-17 00:00:00
abstract：:Antitumor and immunomodulatory activities of an aqueous extract (GF100) of Acanthopanax senticosus were examined. In experimental lung metastasis of colon26-M3.1 carcinoma cells, intravenous (i.v.) administration of GF100 2 days before tumor inoculation significantly inhibited lung metastasis in a dose-dependent manne...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2004.03.052
更新日期：2004-08-01 00:00:00
abstract：:In our efforts to find new active tyrosinase inhibitors for skin-whitening or antibrowning preparations, we investigated 67 tropical plants belonging to 38 families, which were evaluated for their anti-tyrosinase activity. The results of our investigation show that extracts of 5 plants, Stryphnodendron barbatimao, Por...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(02)00174-5
更新日期：2002-10-01 00:00:00
abstract：:Traditional medicine used in Central Anatolia; Ankara, Kayseri, Niğde and south-eastern parts of Karaman and Konya provinces have been studied. Two hundred and ninety one folk remedies obtained from 103 plant species belonging to 40 families and 4 animal species are reported with their vernacular names, parts used, me...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(00)00399-8
更新日期：2001-05-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Indigofera argentea Burm. f.; commonly known as neel, jantari, hathio; is traditionally used for the treatment of headache, fever, inflammation and body pain. Local communities also used this plant for the treatment of malaria, jaundice, vertigo and gastric disorders. AIM OF THE STUDY:Th...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.112966
更新日期：2020-09-15 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Cimicifuga foetida L., a traditional Chinese medicine, has been used as an anti-inflammatory, antipyretic and analgesic remedy. The primary active constituents are believed to be present in the triterpene glycoside fraction. MATERIALS AND METHODS:To develop an LC-MS/MS assay for four maj...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2012.06.031
更新日期：2012-08-30 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Artemisia asiatica Nakai is a traditional herbal plant that has long been used in anti-inflammatory, anti-infective and skin protective remedies. AIM OF THE STUDY:In this study, traditionally known skin-protective activity of Artemisia asiatica Nakai was examined with its ethanol extract...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2018.03.037
更新日期：2018-06-28 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Nepeta is a multiregional genus of the "Lamiaceae" (Labiatae or Mint) family. Species of Nepeta are a valuable part of traditional medicine and used extensively, particularly in the Himalayan region of India (Uttarakhand, Himachal Pradesh, Jammu and Kashmir, Leh-Ladakh), Pakistan (Khyber ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2020.113679
更新日期：2021-03-25 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Cola nitida is amongst the evergreen plants native to West Africa used in the treatment of various ailments including diabetes. AIM OF THE STUDY:This study aims to investigate the antidiabetic effects of the hot water extract of C. nitida seeds in type 2 diabetic rats. METHODS:Type 2 di...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2019.112033
更新日期：2019-10-05 00:00:00
abstract：:Plant material from 34 Amazonian species of the family Euphorbiaceae were collected and extracts prepared. Sixteen of these species have a documented use as a medicinal agent. The extracts were tested for their ability to inhibit the growth of the bacteria, Escherichia coli and Staphylococcus aureus; the yeasts, Sacch...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/0378-8741(88)90124-9
更新日期：1988-02-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Clerodendrum phlomidis L.f., is used to treat several inflammatory diseases and arthritis in Indian traditional system and folk medicine. AIM OF THE STUDY:The aim of the present study was to evaluate the scientific basis of antiinflammatory activity of different organic solvent extracts ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2011.04.028
更新日期：2011-06-01 00:00:00
abstract：AIM OF THE STUDY:The objectives of this study were to investigate the adjuvant anti-tumor effects of Antrodia camphorate in human hepatoma cells (C3A and PLC/PRF/5) which are resistance to most anti-tumor agents, elucidate the possible regulation pathways, and measure the tumor growth and survival rate in xenograft-nud...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2008.05.001
更新日期：2008-08-13 00:00:00
abstract：:In the present study, the anti-inflammatory activity of 70% ethanolic extract of Pongamia pinnata leaves (PLE) in acute, subacute and chronic models of inflammation was assessed in rats. Per os (p.o.) administration of PLE (300, 1000 mg/kg) exhibited significant anti-inflammatory activity in acute (carrageenin, histam...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(01)00333-6
更新日期：2001-12-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Synadenium grantii Hook. f., popularly known as "janaúba" or "leiterinha", is used in the folk medicine to treat gastric disorders, some types of neoplasias and inflammatory diseases. AIM OF THE STUDY:The aim of this study was to show the anti-inflammatory activity of the methanol extrac...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.113487
更新日期：2021-03-01 00:00:00
abstract：AIM OF THE STUDY:JZXS has been used for inflamed hemorrhoids as a chinese prescription for several decades. The present study was designed to investigate the anti-inflammatory activities, as well as the mechanisms, of an active ingredients group (AIG) obtained from Jinxuan Zhike Xunxi San (JZXS). MATERIALS AND METHODS...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2011.03.019
更新日期：2011-05-17 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Ginsenoside Rg3 from Panax ginseng has reported to have multiple pharmacological activities including anti-diabetics, anti-inflammation and anti-cancer. However, the effect of ginsenoside Rg3 on myogenic differentiation and muscle atrophy is unknown. AIM TO THE STUDY:In this study, we in...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2019.112054
更新日期：2019-10-05 00:00:00
abstract：:Oleanolic acid and ursolic acid are ubiquitous triterpenoids in plant kingdom, medicinal herbs, and are integral part of the human diet. During the last decade over 700 research articles have been published on their research, reflecting tremendous interest and progress in our understanding of these triterpenoids. This...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章,评审
doi：10.1016/j.jep.2005.05.024
更新日期：2005-08-22 00:00:00
abstract：:Lithospermi radix (LR, root of Lithospermum erythrorhizon Siebold. et Zuccarinii) has been used to treat various conditions, such as septic shock, eczema and burns. In this study, the effect of LR on lipopolysaccharide (LPS) and recombinant interferon-gamma (rIFN-gamma)-induced production of nitric oxide (NO) and tumo...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2005.06.028
更新日期：2005-12-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Triple-negative breast cancer (TNBC) often presents with a high histological grade and high malignancy, which greatly contribute to patient morbidity and mortality. Rhizoma Amorphophalli exhibits many biological and pharmacological activities, but its potential as a therapeutic agent for ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2017.09.033
更新日期：2018-01-30 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Mesua ferrea Linn. (Cluciaseae), Cobra's saffron, is named after the heaviness of its timber and is cultivated in tropical climates for its form, foliage, and fragrant flowers. It is prescribed in the Ayurvedic literature for the treatment of pain, inflammation, and rheumatic conditions. ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2011.09.042
更新日期：2011-12-08 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Magnesium lithospermate B (MLB), an active polyphenol acid of Radix Salviae Miltiorrhizae (Danshen), showed a wide range of pharmacological activities in cardiovascular diseases. However, its role in protection against ischemia/reperfusion injury in H9c2 cardiomyocytes has not been elucid...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.11.036
更新日期：2014-01-01 00:00:00
abstract：:Pseudo-akuammigine, an alkaloid from Picralima nitida seed extract was investigated for anti-inflammatory and analgesic actions using the carrageenan-induced rat paw oedema and the rat tail flick. The alkaloid, at 1.0, 5.0 and 50 mgkg(-1)(,) dose-dependently inhibited the mean maximal paw swelling attained during 6 h ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(02)00058-2
更新日期：2002-06-01 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Phragmanthera incana (Schum) Balle is a member of the African mistletoes that has been reported to be used in ethnomedicine for the treatment of hypertension. AIM:The aim of this study was to investigate the antihypertensive effect of Phragmanthera incana leaf ethanol extract (PILEE) in ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2020.112888
更新日期：2020-07-15 00:00:00
abstract：:Bakera, a steam bath prepared with various plants, is a traditional method used in Minahasa (North Sulawesi, Indonesia) for recuperation after childbirth. Semi-structured interviews were conducted with 14 midwives and 166 mothers in different villages of Minahasa, in order to document the preparation and plants used f...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2007.01.016
更新日期：2007-05-22 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Gongjin-Dan is a representative traditional Oriental medicine herbal drug that has been used to treat chronic fatigue symptoms for several hundred years. We evaluated the anti-fatigue effects of Gongjin-Dan and the underlying mechanisms in a chronic forced exercise mouse model. METHODS A...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2015.04.001
更新日期：2015-06-20 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:The leaves of Clausena anisata are used traditionally to expel maggots from wounds of animals in Zimbabwe. We have previously proved in the laboratory that the plant certainly affects the behaviour and growth of blowfly larvae. The objective of this study was to isolate and identify the a...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2013.09.037
更新日期：2013-12-12 00:00:00
abstract：:The combined effects of 5-fluorouracil (5-FU) and carp (Cyprinus carpio L.) extract on antitumor activity, myelotoxicity and gastrointestinal toxicity were examined in sarcoma 180-bearing mice. Carp extract was found to prevent the occurrence of myelotoxicity as determined by the reduction of leukocyte number, and of ...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/s0378-8741(99)00126-9
更新日期：1999-12-15 00:00:00
abstract：ETHNOPHARMACOLOGICAL RELEVANCE:In Togo, many persons still rely on plants for healing, however very little is known about the medicinal practices of the indigenous people. The present study aimed to document the medicinal plant utilization for the management of liver diseases in the Maritime region of the country. MET...
journal_title：Journal of ethnopharmacology
pub_type： 杂志文章
doi：10.1016/j.jep.2015.12.051
更新日期：2016-04-02 00:00:00
