Guidelines for the treatment of adults with severe head trauma (part I). Initial assessment; evaluation and pre-hospital treatment; current criteria for hospital admission; systemic and cerebral monitoring.

Abstract:

:If pragmatic recommendations for treatment of severely head-injured patients could really be applied, they would probably have a considerable impact in terms of reduction in mortality and disability. Since 1995 a Group of Italian Neurointensivists and Neurosurgeons belonging to the Italian Societies of Neurosurgery (SINch) and Anesthesiology & Intensive Care (SIAARTI) has produced this first part of recommendations that are completed by Medical treatment (Part II) and Surgical treatment criteria (Part III). These recommendations reflect a multidisciplinary consent but are based on scientific evidence, when available, and take origin mainly from expert opinions and the current clinical and organizational situation. For this aspect they differ from other American and European guidelines, which are strictly based on criteria of proven efficacy. These recommendations aim at providing a practical reference for all those dealing with severe head injuries from first-aid to intensive care units, setting out the minimal goals of management to be reached throughout the country. For these reasons they need continual critical review and updating. Main clinical aims are: 1) to prevent secondary cerebral damage by continuous and meticulous maintenance of systemic homeostasis 2) to standardize methods of neurological evaluation and CT scan classification and scheduling; 3) to give simple indications for systemic and cerebral monitoring 4) to pragmatically discuss the organizational scenarios and specify the minimal safe clinical approach when patients are treated in non-specialized settings. Briefly, smooth tracheal intubation and ventilation in all comatose patients, administration of rapidly metabolized sedative and analgesic drugs to permit frequent neurological evaluation, restoration of volemia and systolic blood pressure above 110 mm Hg, oxygen saturation >95% and normocapnia, are all recommended from the very early treatment and transport. Homogeneity of language, reliable and correctly tested Glasgow Coma Score and pupillary reflexes, and a simple CT scan classification are recommended to improve communications and clinical decisions in the multidisciplinary setting of management. In comatose patients, cerebral perfusion pressure, intracranial pressure and oxygen jugular saturation must be monitored according to specific criteria, which are described. Therapy with hyperventilation and mannitol should be used only in case of clinical deterioration and uncal herniation. This therapy could be useful to gain time to reach neurosurgery. The aim of these recommendations is to achieve safer management of severely brain injured patients, immediate diagnosis of clinical deterioration and successful identification and treatment of surgical lesions. The impact of these guidelines requires further verification.

journal_name

J Neurosurg Sci

authors

Procaccio F,Stocchetti N,Citerio G,Berardino M,Beretta L,Della Corte F,D'Avella D,Brambilla GL,Delfini R,Servadei F,Tomei G

keywords:

subject

Has Abstract

pub_date

2000-03-01 00:00:00

pages

1-10

issue

1

eissn

0390-5616

issn

1827-1855

journal_volume

44

pub_type

指南,杂志文章,实务指引
  • Inhibiting action human glioblastoma extract on haemolytic complement of human and xenogeneic sera.

    abstract::The action of some extracts of human glioblastoma of the haemolytic complement of human and xenogeneic sera has been examined. The study suggests that the antigenic products of some human glioblastomas may induce an inhibiting effect on the haemolytic complement of human, as well as xenogeneic (rat and rabbit), sera. ...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Occhiogrosso M,De Tommasi A,Vailati G

    更新日期:1990-04-01 00:00:00

  • Bioinformatics analysis of the gene expression profiles in human intervertebral disc degeneration associated with inflammatory cytokines.

    abstract:BACKGROUND:To investigate the microarray data on the gene expression profiles of intervertebral disc degeneration related to cytokine exposure. The purpose of the study was to identify the key genes that were differentially expressed in these disc cells compared to cells without inflammatory cytokine treatment, using b...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:10.23736/S0390-5616.16.03326-9

    authors: Liu C,Zhang JF,Sun ZY,Tian JW

    更新日期:2018-02-01 00:00:00

  • Rehabilitation interventions for chronic motor deficits with repetitive transcranial magnetic stimulation.

    abstract::Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive electrophysiological method to modulate cortical excitability. As such, rTMS can be used in conjunction with conventional physiotherapy or occupational therapy to facilitate rehabilitation of motor function in patients with focal brain lesions. This...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Paquette C,Thiel A

    更新日期:2012-12-01 00:00:00

  • Patterns of failure in surgical therapy of medulloblastomas.

    abstract::To better understand the relationship between the modalities of the surgical ablation of medulloblastomas--partial versus total tumor exeresis--and the pattern of tumoral relapse (local regrowth or metastases at distance), we have analyzed forty-five children affected by cerebellar medulloblastomas, observed at the Po...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Di Rocco C,Iannelli A,Tancredi A

    更新日期:1995-03-01 00:00:00

  • Traumatic aneurysms of the pericallosal artery in children. Case report.

    abstract::Intracranial aneurysm in children is a rare pathology. Epidemiological studies have indicated that aneurysms in pediatric age are characterized by predominance in male subjects, a frequent great volume and a prevalently distal localization. It is assumed that these factors prove the traumatic origin (accident or birth...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Gallari G,Chibbaro S,Perra G

    更新日期:1997-06-01 00:00:00

  • Isolated oculomotor nerve palsy following apoplexy of a pituitary adenoma.

    abstract::An isolated oculomotor nerve palsy is very rarely the presenting sign of a pituitary adenoma. It may occur slowly due to mechanical compression or rapidly, secondary to pituitary apoplexy. Magnetic resonance imaging (MRI) with and without gadolinium DTPA enhancement provides excellent anatomical detail and is useful i...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Rossitch E Jr,Carrazana EJ,Black PM

    更新日期:1992-04-01 00:00:00

  • Francesco Rizzoli (1809-1880) and the elusive case of Giulia: the description of an ''arteriovenous aneurysm passino through the wall of the skull''.

    abstract::The improved knowledge of clinical and emodynamical aspects of extracranial arteriovenous malformations in the 18 th century provided a foundation for the understanding and treatment of cerebrovascular pathology. It was not until the late 19 th century that detailed clinicopathological reports of intracranial arteriov...

    journal_title:Journal of neurosurgical sciences

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Perrini P,Nannini T,Di Lorenzo N

    更新日期:2007-03-01 00:00:00

  • Occult dysraphism in adulthood. A series of 24 cases.

    abstract::The results of a retrospective study of 24 adult patients with occult dysraphism are described. There were 15 males and 9 females, with an average age of 31.1 years. Specific circumstances precipitated symptomatic onset in 67% of patients. Pain, often referred to the anorectal region, was the most common presenting sy...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Caruso R,Cervoni L,Fiorenza F,Vitale AM,Salvati M

    更新日期:1996-09-01 00:00:00

  • Rupture of giant cerebral aneurysms during angiography. Case report and review of literature.

    abstract::A case of a giant aneurysm of the internal carotid artery which ruptured during cerebral angiography is reported. 30 other cases from literature of the last 35 years are reviewed. The majority of aneurysms ruptured during angiography was located at the internal carotid artery. 21 out of 30 patients were females. Fatal...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Behr R,Agnoli AL,Zierski J

    更新日期:1988-10-01 00:00:00

  • Surgical treatment of 100 single brain metastases. Analysis of the results.

    abstract::The authors report their personal series of 100 consecutive surgically treated single brain metastases between 1981 and 1988. Patients selection was decided with respect to general and neurological conditions and to primary cancer development. Resection was mostly radical, postoperative mortality rate was 6% and neuro...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Ferrara M,Bizzozzero L,Talamonti G,D'Angelo VA

    更新日期:1990-07-01 00:00:00

  • IGF-1: an endogenous link between traumatic brain injury and Alzheimer disease?

    abstract::There is a growing body of evidence that the insulin-like growth factor-1 (IGF-1) is dynamically involved in the regulation of body homeostasis and glucose regulation. Traumatic brain injury (TBI) is considered to be a risk factor for Alzheimer's disease (AD). As alterations of IGF-1 have been implicated in both TBI a...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章,评审

    doi:10.23736/S0390-5616.16.03431-7

    authors: Zheng P,Tong W

    更新日期:2017-08-01 00:00:00

  • Stereotactic radiosurgery of brain metastases.

    abstract::Brain metastases are a common problem in solid malignancies and still represent a major cause of morbidity and mortality. With the ongoing improvement in systemic therapies, the expectations on the efficacy of brain metastases directed treatment options are growing. As local therapies against brain metastases continue...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Specht HM,Combs SE

    更新日期:2016-09-01 00:00:00

  • The dysraphic state of the posterior fossa. Clinical review of the Dandy-Walker syndrome and the so-called arachnoid cysts.

    abstract::The Authors report their case material concerning some basic items of the dysraphic pathology of the Posterior Fossa: 22 cases of Dandy Walker syndromes (DWS) and "Arachnoid Cysts" (PFC). The mean clinical findings (predominant involvement of the vestibular structures of the brain stem in the DWS, frequent epileptic s...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Carteri A,Gerosa M,Gaini SM,Villani R

    更新日期:1979-01-01 00:00:00

  • Spinal epidural abscess as a complication of Fournier's gangrene.

    abstract::Fournier's gangrene is a rare, multi-organism infection of the perineum. The disease is most often confined to the groin area with distant spread being extremely unusual. A ase of spinal epidural abscess as a complication of Fournier's gangrene is presented. The infection appears to have spread by the hematogenous rou...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Rossitch E Jr,Maggio MI,Anderson EE

    更新日期:1991-10-01 00:00:00

  • Computed tomography in the management of spinal cord arteriovenous malformations.

    abstract::This is a report of two cases of intramedullary arteriovenous malformations (AVMs) where computed tomography (CT) was used as a complementary diagnostic investigation. CT scan features in these two cases are briefly discussed. ...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Guglielmi G,Dazzi M,Guidetti G,Spallone A

    更新日期:1984-01-01 00:00:00

  • Minimally invasive lumbar decompression for lumbar stenosis: review of clinical outcomes and cost effectiveness.

    abstract::Lumbar stenosis patients typically present with neurogenic claudication or radiculopathy. Studies have shown the benefit of surgical management of lumbar stenosis for patients who fail medical management. Surgical management traditionally involved an open laminectomy and foramenotomies. The emergence of minimally inva...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Johans SJ,Amin BY,Mummaneni PV

    更新日期:2015-03-01 00:00:00

  • Intradiploic hematoma in a patient who underwent internal drainage of CSF for hydrocephalus.

    abstract::The authors report the case of an encapsulated intradiploic hematoma observed in a 2 year old patient who, 6 months prior to their observation, underwent an internal CSF drainage for hydrocephalus. The surgical findings are described and the possible etiopathological causes discussed. ...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Giammusso V,Strukelj S

    更新日期:1980-04-01 00:00:00

  • Functional outcome of patients with unstable single- level/ two- level lumbar stenosis treated with decompression plus divergent screws (cortical bone trajectory) or percutaneous convergent pedicle screws.

    abstract:BACKGROUND:The aim of this prospective comparative study is to assess the functional outcome in two groups of patients suffering from spinal lumbar instability and treated by decompression and stabilization with posterior lumbar interbody fusion using percutaneous pedicle screws (PCT) or a novel technique of divergent ...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:10.23736/S0390-5616.20.04893-6

    authors: De Bonis P,Chiccoli M,Visani J,Cavallo MA,Scerrati A

    更新日期:2020-02-25 00:00:00

  • Pycnogenol® supplementation in minimal cognitive dysfunction.

    abstract:BACKGROUND:Impairments in cognitive function are difficult to evaluate and measure. In most cases, subjects do not perceive any alteration in their own status, particularly in case of mild cognitive impairment. In case of minimal alterations of cognitive function, no real treatment exists at the moment. Functional and/...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:10.23736/S0390-5616.18.04382-5

    authors: Hosoi M,Belcaro G,Saggino A,Luzzi R,Dugall M,Feragalli B

    更新日期:2018-06-01 00:00:00

  • Spontaneous pneumo-cephalus caused by otogenous temporal abscess.

    abstract::The Authors report a rare case of spontaneous intraparenchymal and intraventricular pneumocephalus, caused by the external rupture of an otogenous temporal abscess. ...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Davini V,Rivano C,Tercero E

    更新日期:1974-07-01 00:00:00

  • The Kluver-Bucy syndrome.

    abstract::Evolution of psychological disorders following head injury including memory disorders and other cognitive ones are common. The best known are psychiatric disturbances of various kind after lesions of frontal lobes. Cognitive, behavioural and emotional disorders are not usually seen in patients with bilateral temporal ...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Góscínski I,Kwiatkowski S,Polak J,Orlowiejska M,Partyk A

    更新日期:1997-09-01 00:00:00

  • Vitamin D status in cervical spondylotic myelopathy: comparison of fusion rates and patient outcome measures.

    abstract:BACKGROUND:Patients undergoing elective spinal fusion have an alarming rate of vitamin D deficiency, but its impact on bone fusion and patient outcomes is unclear. We investigated the association of perioperative vitamin D levels, fusion rates, and patient-reported outcome in patients undergoing spinal fusion for cervi...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:10.23736/S0390-5616.16.03846-7

    authors: Ravindra VM,Guan J,Holland CM,Dailey AT,Schmidt MH,Godzik J,Hood RS,Ray WZ,Bisson EF

    更新日期:2019-02-01 00:00:00

  • A rare case of intracranial solitary fibrous tumor of meninges: case report.

    abstract::The authors report a case of intracranial tumor in a 60 year female, previously asymptomatic presenting with altered sensorium following a road traffic accident. Imaging showed a small left frontotemporal contusion along with a large right frontoparietal extra axial mass lesion suggestive of a meningioma. Patient impr...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Sai Kiran NA,Kasliwal MK,Gupta A,Mridha AR,Sharma MC,Sharma BS

    更新日期:2009-12-01 00:00:00

  • A huge intramedullary epidermoid cyst: mimicking cauda equina ependymoma. Diagnostic failure of myelography and myelo-CT.

    abstract::Intraspinal epidermoid tumors are rare and the intramedullary location is quite uncommon. In this report, a 48-year-old patient with intramedullary epidermoid cyst mimicking a cauda equina ependymoma is presented and diagnostic failure of conventional myelography and Myelo-CT is questioned and related literature is re...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Biliciler B,Vatansever M,Fuat Erten S,Saraç K,Colak A

    更新日期:1996-06-01 00:00:00

  • High cervical (C2-C3) spondylogenetic myelopathy treated by transoral approach. Case report.

    abstract::It is reported a case that required transoral exposure of C2-C3 intervertebral space in order to remove a huge osteophyte spur projecting into the spinal canal and producing a severe myelopathy. This unusual surgical route was used because the relevant interspace was inaccessible via the standard anterior approach due...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Di Lorenzo N,Fortuna A

    更新日期:1987-04-01 00:00:00

  • Spinal intramedullary ependymoma: surgical approaches and outcome.

    abstract::Intramedullary ependymomas are uncommon tumors that can occur within the medullary substance of the spinal cord. Despite this difficult location, they are typically benign tumors that can most often be removed completely with an acceptable surgical risk. Therefore, the recommended management approach is usually surgic...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章,评审

    doi:10.23736/S0390-5616.17.04162-5

    authors: Borges LF

    更新日期:2018-02-01 00:00:00

  • Spontaneous rupture of spinal dermoid cyst with disseminated lipid droplets in central canal and ventricles.

    abstract::Free fat in the ventricular space is a rare but well recognized complication of ruptured tumour of dermal origin. However, only 1 patient of spontaneous rupture of spinal dermoid tumour with disseminated fat in the central canal and ventricles has been described in the literature. The authors report an extremely rare ...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Goyal A,Singh D,Singh AK,Gupta V,Sinha S

    更新日期:2004-06-01 00:00:00

  • Association between carotid artery tortuosity and carotid dissection: a case-control study.

    abstract:BACKGROUND:Carotid artery dissections have long been associated with compromise of the structural integrity of the arterial wall from heritable connective-tissue disorders, hypertension, and trauma. However, an association between spontaneous internal carotid artery dissection and tortuous or redundant carotid anatomy ...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:10.23736/S0390-5616.16.03790-5

    authors: Kim ST,Brinjikji W,Lehman VT,Carr CM,Luetmer PH,Rydberg CH

    更新日期:2018-08-01 00:00:00

  • Cavernous sinus tumors: neuroradiologic and neurosurgical considerations on 150 operated cases.

    abstract::We reviewed the neuroimaging studies of 150 patients with cavernous sinus tumors operated on during an 8-year period. Meningiomas (66 cases), chordomas (18 cases), trigeminal neurolemmomas (12 cases), and chondrosarcomas (11 cases) were the most common diagnosed neoplasms. Neuroradiological findings are briefly descri...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:

    authors: Lanzino G,Hirsch WL,Pomonis S,Sen CN,Sekhar LN

    更新日期:1992-10-01 00:00:00

  • Comparison between the different types of heterologous materials used in cranioplasty: a systematic review of the literature.

    abstract:INTRODUCTION:The choice of heterologous materials for cranioplasty after decompressive craniectomy is still difficult. The aim of this study is to examine the association between material of choice and related complications to suggest the best treatment option. EVIDENCE ACQUISITION:A systematic review was performed fo...

    journal_title:Journal of neurosurgical sciences

    pub_type: 杂志文章

    doi:10.23736/S0390-5616.19.04779-9

    authors: Morselli C,Zaed I,Tropeano MP,Cataletti G,Iaccarino C,Rossini Z,Servadei F

    更新日期:2019-12-01 00:00:00