Abstract:
:The objective of this study was to quantify familial resemblance for coronary heart disease risk in 260 Black and 427 White participants in the HERITAGE Family Study. Coronary heart disease risk was estimated using a coronary heart disease risk index (CHDRI) computed from the revised Framingham Heart Study algorithm, based on age, LDL-cholesterol, HDL-cholesterol, blood pressure, diabetes, and smoking status. Using a familial correlation model to test hypotheses regarding familial aggregation, significant familial resemblance was detected in both Blacks and Whites. There were significant sibling correlations in both Blacks and Whites, while spouse correlations were significant only in the White sample. The maximal heritabilities, which have to be interpreted cautiously in light of negligible parent-offspring correlations, were 34% and 53% in Whites and Blacks, respectively. Thus, the maximal heritability, which includes both genetic and non-genetic sources of variation, is higher in Blacks than Whites, and explains a significant proportion of the total phenotypic variance. The results indicate that risk of coronary heart disease runs along family lines, and common environmental effects are important in explaining the observed familial resemblance.
journal_name
Ethn Disjournal_title
Ethnicity & diseaseauthors
Katzmarzyk PT,Perusse L,Rice T,Gagnon J,Skinner JS,Wilmore JH,Leon AS,Rao DC,Bouchard Ckeywords:
subject
Has Abstractpub_date
2000-04-01 00:00:00pages
138-47issue
2eissn
1049-510Xissn
1945-0826journal_volume
10pub_type
杂志文章abstract::According to the third National Health and Nutrition Examination Survey, African Americans have a lower prevalence of metabolic syndrome than do Whites. Recent reports in Blacks in other regions have confirmed these observations, but the rates vary. This lower rate of metabolic syndrome in Blacks can be partly ascribe...
journal_title:Ethnicity & disease
pub_type: 杂志文章,评审
doi:
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:Post-stroke depression (PSD) is common and associated with poor stroke outcomes, but few studies have examined race/ethnic disparities in PSD. Given the paucity of work and inconsistent findings in this important area of research, our study aimed to examine race/ethnic differences in depression in a multi-eth...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:10.18865/ed.26.1.1
更新日期:2016-01-21 00:00:00
abstract:Objective:This article describes Mayors Mentoring Mayors (3M), an initiative of the Arkansas Coalition for Obesity Prevention (ArCOP), which expanded to five states to become the signature community initiative of the Mid-South Transdisciplinary Collaborative Center (Mid-South TCC) for Health Disparities Research. Meth...
journal_title:Ethnicity & disease
pub_type: 杂志文章,多中心研究
doi:10.18865/ed.27.S1.347
更新日期:2017-11-09 00:00:00
abstract::The goal of this study was to assess benefits, barriers, attitude, and beliefs about nutrient content and health effects, and sensory analysis of soy meat-alternatives among 40 African Americans, mean (SD) aged 54 (10), 78% of whom were females, participating in a faith-based nutrition program. Perceived benefits rece...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVES:Few studies have objectively quantified sedentary behavior, particularly in special population subgroups. This study quantified the volume of and breaks from sedentary behavior in a sample of overweight and obese, primarily African American, women. DESIGN:Cross-sectional. SETTING:18 census tracts in Columb...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2013-07-01 00:00:00
abstract::Facing the conclusion of the twentieth century, cardiovascular disease (CVD) remains a major cause of morbidity and a leading contributor to mortality worldwide. Developing countries, including those in South America and the Caribbean, contribute substantially to the global burden of CVD. Indeed, 8 to 9 million deaths...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:1999-10-01 00:00:00
abstract:Objective:Immigrants, especially refugees, face unique barriers to accessing health care relative to native born Americans. In this study, we examined how immigration status, health, barriers to access, and knowledge of the health care system relate to the likelihood of having a regular health care provider. Methods:U...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:10.18865/ed.29.2.253
更新日期:2019-04-18 00:00:00
abstract::This paper focuses on understanding the perilous effects of interpersonal and institutional racism on the psychological and physiological well-being of Blacks. Interpersonal racism refers to prejudice and discriminatory behaviors directed toward individuals because of their race or ethnicity, and institutional racism ...
journal_title:Ethnicity & disease
pub_type: 杂志文章,评审
doi:
更新日期:2001-10-01 00:00:00
abstract::This report contains information from the Health Policy Summit, held in conjunction with the Fifth Annual Primary Care Conference and the Tenth Annual HeLa Women's Health Conference. During this Summit's presentation, Warren A. Jones, MD provided information on the Medicaid system and the challenges facing administrat...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:The inclusion of women and minorities in health research supported by the National Institutes of Health (NIH) has received increasing attention since the adoption of related guidelines by NIH in 1990. Investigators in population-based and clinical research may need to identify and recruit research participant...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract:INTRODUCTION:Health disparities research demands the inclusion of traditionally excluded peoples. Additional complex issues weigh into health disparities or multicultural research including sociopolitical context, cultural context, network or community context, and micro-level or personal dimensions. CONCEPTUAL FRAMEW...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Advancing health equity and reducing disparities through evidence-based policy research requires the expertise, insights, and active participation of various policy stakeholders - particularly those representing vulnerable populations who may be disproportionately affected by such policies. Unfortunately, there are fe...
journal_title:Ethnicity & disease
pub_type: 社论
doi:10.18865/ed.29.S2.323
更新日期:2019-06-13 00:00:00
abstract::The purpose of this study was to investigate whether there are differences in the expression of the endothelin (ET) system in the peripheral vasculature of diabetic African-American (AA) and Caucasian (CA) patients. Tibial artery specimens were obtained from diabetic (MD = 8 and CAD = 5) and non-diabetic (AAND = 6 and...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:Studies have demonstrated the effects of segregated social and physical environments on the development of chronic diseases for African Americans. Studies have not delineated the effects of segregated environments specifically on the health of African American men over their lifetime. This study examines the re...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:10.18865/ed.25.3.295
更新日期:2015-08-07 00:00:00
abstract::Patients from the Indian subcontinent have a distinct cardiovascular risk profile with profound health consequences. South Asians tend to develop more severe coronary artery disease at a younger age, and may also suffer from earlier myocardial infarction and heart failure. The genesis of this risk is multi-factorial. ...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2010-10-01 00:00:00
abstract::Diabetes is the seventh leading cause of death in the United States and disproportionately affects ethnic minorities. While research examining health disparities is well-established, an historical understanding of how the disparities evolved over time may be warranted. This article examined racial differences in preva...
journal_title:Ethnicity & disease
pub_type: 历史文章,杂志文章
doi:
更新日期:2015-01-01 00:00:00
abstract::In the 20th century, Africans in Sub-Saharan Africa had lower rates of cardiometabolic disease than Africans who migrated. However, in the 21st century, beyond infectious diseases, the triple epidemics of obesity, diabetes and hypertension have taken hold in Africa. Therefore, Africans are acquiring these chronic dise...
journal_title:Ethnicity & disease
pub_type: 杂志文章,评审
doi:10.18865/ed.25.3.373
更新日期:2015-08-07 00:00:00
abstract:OBJECTIVE:To compare demographic and clinical characteristics among 3 ethnic groups of indigent patients exhibiting diabetic ketoacidosis (DKA), in Houston, Texas. METHODS:Over a span of 3.5 years, 321 patients were interviewed at the time of admission for DKA. Demographic, clinical, and biochemical data and measures ...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
abstract::The design, implementation, and preliminary evaluation of an enhanced community-engagement program that uses poetry, film, and photography at a film festival in south Los Angeles is described. This project is one of several Talking Wellness projects designed to develop social capital and enhance community engagement i...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To identify any differences in hospitalization rates of diabetes patients by age, sex, or race/ethnicity. DESIGN:A cross-sectional study of Georgia hospital discharge data between 1998 and 2001. PATIENTS/PARTICIPANTS:Patients with a principal discharge diagnosis of diabetes. MAIN OUTCOME MEASURES:Adjusted ...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Substantial disparities in colorectal cancer (CRC) survival among racial-ethnic groups, especially between Blacks and Whites, have been extensively documented in the Northeast, California and South of the United States. The purpose of this study was to ascertain the determinants of colorectal cancer racial-e...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Minority girls are disproportionately affected by overweight and obesity. The independent effects of physical activity (PA), sedentary behavior (SB), and diet are not well understood. OBJECTIVE:This study examined the individual influences of PA, SB and diet on fat mass in Latina and African American (AA) g...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:This cross-sectional study was designed to examine the association between adiponectin and cardiovascular disease (CVD) among an understudied ethnic group of Filipino American women. METHODS:We recruited 266 Filipino women aged 40-86 years from the University of California, San Diego Filipino Women's Health...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVES:To describe the association between renal disease and other features of the metabolic syndrome and its derivative illnesses among Australian Aborigines in remote settings. METHODS:Volunteering adults (N = 2019) in four remote communities were screened for risk factors and markers of renal disease, hypertens...
journal_title:Ethnicity & disease
pub_type: 杂志文章,多中心研究
doi:
更新日期:2006-04-01 00:00:00
abstract::This review article discusses disparities in immunization rates for beneficiaries of the US Medicare program. The review considers: 1) historical and statistical information on rates of immunization; 2) goals set forward by the Centers for Medicaid and Medicare Services (CMS) to eliminate racial and ethnic health disp...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:We assessed racial differences in lipoprotein particle size, a marker of atherosclerosis risk, among women with coronary disease. METHODS:We studied 378 women (33% non-White, predominantly African American) at the baseline visit of the Women's Angiographic Vitamin and Estrogen Trial (WAVE), a multicenter tr...
journal_title:Ethnicity & disease
pub_type: 杂志文章,多中心研究
doi:
更新日期:2008-04-01 00:00:00
abstract::Sickle cell disease is the most commonly inheritable blood disorder in man. Sickle cell anemia affects approximately one in 375 Blacks in the United States. There is yet no known cure for this disease. Families of sickle cell patients continue to be financially and emotionally devastated by sickle cell disease complic...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract:OBJECTIVES:To examine the adequacy of available evidence that: 1) left ventricular hypertrophy (LVH) and its regression influence the rate of cardiovascular events in hypertension; 2) carotid artery wall thickening and discrete plaque have comparable significance to LVH; and 3) black hypertensive patients have greater ...
journal_title:Ethnicity & disease
pub_type: 杂志文章,评审
doi:
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:Unique challenges exist in the provision of culturally and linguistically appropriate health care to ethnically diverse populations. The purpose of this study was to improve the metabolic control of Russian patients with diabetes through increased attention to language and cultural concordance between the provi...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:2004-10-01 00:00:00
abstract::Though the rate of stroke mortality in the United States has been declining for all race-sex-specific groups, rates for blacks are among the highest in the world. Studies of the geographic and social variation of stroke mortality between populations have focused solely on either trends or social determinants, but not ...
journal_title:Ethnicity & disease
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00