Abstract：
:The purpose of this study was to investigate whether there are differences in the expression of the endothelin (ET) system in the peripheral vasculature of diabetic African-American (AA) and Caucasian (CA) patients. Tibial artery specimens were obtained from diabetic (MD = 8 and CAD = 5) and non-diabetic (AAND = 6 and CAND = 5) patients undergoing lower limb amputation. The gene expression of ET-1 precursor (PPET-1), ET(A)R and ET(B)R was determined by a reverse transcriptase polymerase chain reaction technique. PPET-1 and ET(A)R expression was up-regulated 4- and 3-fold, respectively, in both AA and CA diabetics (P<.05 vs non-diabetics). ET(B)R mRNA was significantly lower in AA diabetic patients. Function of ET-1 and ET receptors was assessed by vascular contractility assays. Vascular relaxation in response to sodium nitroprusside in arteries precontracted with ET-1 was significantly lower in AA (58% +/- 9) as compared to CA diabetics (74% +/- 5) (P<.05). In conclusion, this study demonstrated that the ET system is altered in favor of the contractile phenotype in AA diabetics and may contribute to the increased incidence of vascular complications in this population.
journal_name
Ethn Disjournal_title
Ethnicity & diseaseauthors
Brothers TE,Grubbs AL,Zhang Y,Ergul Akeywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
S1-46-50issue
1eissn
1049-510Xissn
1945-0826journal_volume
12pub_type
杂志文章abstract：OBJECTIVE:This study examines the cancer prevention and control priorities of uninsured Latin Americans and their primary care providers in metropolitan Washington, D.C. Patient and provider priorities are compared to identify common ground for future interventions in resource constrained primary care settings. METHOD...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2002-07-01 00:00:00
abstract：:This report contains information from the Health Policy Summit, held in conjunction with the Fifth Annual Primary Care Conference and the Tenth Annual HeLa Women's Health Conference. During this Summit's presentation, Warren A. Jones, MD provided information on the Medicaid system and the challenges facing administrat...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:The inclusion of women and minorities in health research supported by the National Institutes of Health (NIH) has received increasing attention since the adoption of related guidelines by NIH in 1990. Investigators in population-based and clinical research may need to identify and recruit research participant...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:The purpose of this study is to report the findings of the 2004 National Health Interview Survey (NHIS) questions on tuberculosis (TB) knowledge and perceived risk of contracting TB. Tuberculosis (TB) continues to be a major health threat in the United States, but minimal effort is made on public education to increase...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVES:To ascertain the extent to which residence in violent communities is an independent risk factor for adverse pregnancy outcomes among impoverished (census tract median family income < $10,000/year) African-American mothers. DESIGN:A cross-sectional study was performed. METHODS:We performed multivariate anal...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVE:To ascertain the association of -3826 A/G polymorphism with blood pressure and different obesity markers. DESIGN AND SUBJECTS:A total of 96 adult participants (49 males, 47 females) were studied. Anthropometric measurements and blood pressure were taken using standardized techniques. Obesity indices of body ...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2012-04-01 00:00:00
abstract：:This review article discusses disparities in immunization rates for beneficiaries of the US Medicare program. The review considers: 1) historical and statistical information on rates of immunization; 2) goals set forward by the Centers for Medicaid and Medicare Services (CMS) to eliminate racial and ethnic health disp...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2005-04-01 00:00:00
abstract：:An exploratory qualitative study was undertaken in Luton to examine the issues that may underlie the severe shortage of organ donors from the United Kingdom's (UK) Asian population. To date, this subject area had not been researched within this sub-population of the UK. Thus, focus groups were employed as the initial ...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2001-10-01 00:00:00
abstract：Objective:To build upon research that investigates the health significance of familial and former incarceration with special emphasis on obesity risk among native-born Black (ie, African American) men. Methods:We analyzed data from the 2001-2003 National Survey of American Life (NSAL), focusing on native-born Black me...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：10.18865/ed.28.2.69
更新日期：2018-04-26 00:00:00
abstract：OBJECTIVE:To establish the baseline prevalence rates for non-communicable disease risk factors in Eritrea. STUDY DESIGN:A cross-sectional survey was conducted among all the ethnic groups in Eritrea with the WHO STEPwise approach. Hypertension was defined as blood pressure > or = 140/90 mm Hg or a person on medication ...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2006-04-01 00:00:00
abstract：:The conceptualization of perceived racism as a chronic stressor is relatively new to epidemiology. The Telephone-Administered Perceived Racism Scale (TPRS) captures the complexity of racism within five scales: Experience of Racism (by Blacks as a group and by the respondent), Emotional Responses, Behavioral Responses,...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：PURPOSE:Studies have demonstrated the effects of segregated social and physical environments on the development of chronic diseases for African Americans. Studies have not delineated the effects of segregated environments specifically on the health of African American men over their lifetime. This study examines the re...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：10.18865/ed.25.3.295
更新日期：2015-08-07 00:00:00
abstract：BACKGROUND:Although minority populations suffer a disproportionately higher burden of tobacco-attributable morbidity and mortality, the church appears to be a promising avenue through which to pursue tobacco-cessation interventions in these communities. This report describes church-related correlates of tobacco use amo...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:We previously developed an 8-item self-assessment tool to identify individuals with a high probability of having albuminuria. This tool was developed and externally validated among non-Hispanic Whites and non-Hispanic Blacks. We sought to validate it in a multi-ethnic cohort that also included Hispanics and C...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：10.18865/ed.25.4.427
更新日期：2015-11-05 00:00:00
abstract：:Though the rate of stroke mortality in the United States has been declining for all race-sex-specific groups, rates for blacks are among the highest in the world. Studies of the geographic and social variation of stroke mortality between populations have focused solely on either trends or social determinants, but not ...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：OBJECTIVE:To quantify cultural barriers to hepatitis B virus (HBV) vaccination and parental compliance with a specific vaccination protocol among a primarily among population of infants born at a community hospital. METHODS:This study was concurrent with an immunogenicity study of two vaccination schedules and occurre...
journal_title：Ethnicity & disease
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2001-10-01 00:00:00
abstract：:Linked maternity data were used to calculate birth intervals from records of 7129 consecutive singleton births to Bangladeshi mothers who delivered in the London borough of Tower Hamlets from 1974 through 1984. During this period, there was active migration of women from Bangladesh, the majority coming to the United K...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：1993-04-01 00:00:00
abstract：BACKGROUND:HIV+ mothers of adolescent girls can serve as agents of change, particularly when it comes to preventing patterns of behaviors that are inherently dangerous. In order to do so these women need to be able to communicate with their daughters and educate them about risk behaviors, especially those associated wi...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:Relationships among sedentary behavior, weight gain, and weight loss and regain are understudied particularly for African Americans, a high risk group for obesity. The hypotheses were: sedentary behavior is positively associated with current body mass and % of weight loss maintained after initial weight loss...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2015-01-01 00:00:00
abstract：:An estimated 1.2 billion citizens of the world are smokers. In developing countries, half the males smoke. WHO projects a global smoking population of 1.6 billion by the end of the next two decades. Collectively, today the world's smokers annually consume nearly 1,000 cigarettes for every man, woman and child on the p...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2007-07-01 00:00:00
abstract：:For more than 20 years the tobacco industry has considered secondhand smoke to be a threat to its viability. In this article, we describe why secondhand smoke is important to tobacco control and how the tobacco industry's "Latin Project" sought to prevent the creation of smoke-free workplaces and public places in Cent...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：Objective:This study investigated whether HIV testing attitudes, HIV conspiracy beliefs, and reported sexual partner disclosure of HIV/STI status related to one-month self-report HIV testing outcomes following a brief intervention among Black women aged 18-25 years residing in rural Mississippi. Participants:Black wom...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：10.18865/ed.30.2.251
更新日期：2020-04-23 00:00:00
abstract：OBJECTIVE:To examine the utilization of health services and prescription patterns among patients with systemic lupus erythematosus (SLE) followed by primary care physicians and rheumatologists in Puerto Rico. METHODS:The insurance claims submitted by physicians to a health insurance company of Puerto Rico in 2003 were...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVES:Ethnic/racial differences in the prevalence of psychiatric disorders have been reported in hospital studies conducted in the United States, but general population studies find little or no evidence of higher rates of disorder in Black communities than White communities. Thus, ethnic/racial differences in the...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVE:To assess the feasibility, acceptability, and outcomes of 2 versions of a culturally relevant, family-based intervention to prevent excess weight gain in pre-adolescent African-American girls. DESIGN:Three-arm, 12-week parallel group randomized controlled pilot trial. SETTING:Community centers in Memphis, T...
journal_title：Ethnicity & disease
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-01-01 00:00:00
abstract：BACKGROUND:We assessed racial differences in lipoprotein particle size, a marker of atherosclerosis risk, among women with coronary disease. METHODS:We studied 378 women (33% non-White, predominantly African American) at the baseline visit of the Women's Angiographic Vitamin and Estrogen Trial (WAVE), a multicenter tr...
journal_title：Ethnicity & disease
pub_type： 杂志文章,多中心研究
doi：
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:The purpose of this article is to examine sociodemographic and health behavior factors associated with dietary intake as measured by the healthy eating index (HEI-2010) for persons with and without diabetes (T2D). DESIGN:A secondary data analysis of three NHANES data cycles spanning 2007-2012. Multiple linea...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：10.18865/ed.26.4.529
更新日期：2016-10-20 00:00:00
abstract：OBJECTIVE:To assess the impact of African American race on hypertension management among a real-world hypertensive population. DESIGN:Cross-sectional study. SETTING:28 US physician practices. PATIENTS:Adult patients with a hypertension diagnosis between November 2006 and September 2008. MAIN OUTCOME MEASURES:Blood ...
journal_title：Ethnicity & disease
pub_type： 杂志文章,多中心研究
doi：
更新日期：2010-10-01 00:00:00
abstract：:So-called 'diseases of lifestyle' are playing a major role in epidemiological transitions in many developing countries. Stratifying, urbanizing, and ageing African populations face rising levels of non-communicable diseases (NCDs). This article examines the need for anthropological perspectives on the causes, preventi...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：:This study examines the influence of ethnicity (African-American vs white) and family history of hypertension on the blood pressure and heart rate responses of healthy, unmedicated men, aged 21 to 39 years, to a variety of stressors that are hypothesized to elicit beta-adrenergic or alpha-adrenergic reactivity. Cardio...
journal_title：Ethnicity & disease
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
