Abstract：
OBJECTIVE:To determine the frequency of pulmonary lymphangioleiomyomatosis (LAM), a rare cystic lung disorder that occurs almost exclusively in women of reproductive age, in women with tuberous sclerosis complex (TSC), an inheritable multiorgan hamartomatosis. PATIENTS AND METHODS:In this retrospective cohort study, the medical records of 78 women with definite TSC were reviewed, and pertinent information was recorded, including the demographic data, clinical manifestations, results of lung biopsies and autopsies, and findings on imaging studies of the chest and abdomen. All available computed tomographic (CT) scans of the chest and abdomen were reviewed. RESULTS:Of 78 women with definite TSC seen from 1977 to 1998, 20 (26%) had evidence of LAM. Surgical lung biopsy or autopsy in 7 patients confirmed the diagnosis of their lung disease. Characteristic CT findings of LAM were noted in 13 additional patients. Twelve of these 20 patients with TSC-associated LAM had respiratory symptoms, including exertional shortness of breath and spontaneous pneumothorax, that eventually led to their pulmonary diagnosis. CONCLUSIONS:The frequency of lung involvement (LAM) in women with TSC is substantially higher than previously suspected and may be even higher than reported in this retrospective study. These findings support the recommendation for a screening CT of the chest for all women with TSC.
journal_name
Mayo Clin Procjournal_title
Mayo Clinic proceedingsauthors
Costello LC,Hartman TE,Ryu JHdoi
10.4065/75.6.591keywords:
subject
Has Abstractpub_date
2000-06-01 00:00:00pages
591-4issue
6eissn
0025-6196issn
1942-5546pii
S0025-6196(11)64585-0journal_volume
75pub_type
杂志文章abstract：:Reperfusion therapy (by either administration of thrombolytic agents or immediate angioplasty) is the mainstay of treatment of acute myocardial infarction, yet it remains underutilized. Additionally, many patients do not experience optimal reperfusion because of suboptimal flow rate in the infarct-related artery, abno...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.4065/70.12.1185
更新日期：1995-12-01 00:00:00
abstract：:A patient simulator has been developed for training, certification, modeling, and demonstrating problems in the management of critical-care patients. The Critical Care & Hemodynamic Monitoring Training System consists of a personal computer, software, and a replica of a human torso designed to enable students to pract...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)65158-1
更新日期：1990-07-01 00:00:00
abstract：:Herein we review the symptoms, physical findings, and test results in 131 patients with acoustic neurinoma. The earliest symptoms are unilateral hearing loss, tinnitus, and dysequilibrium. As the disease progresses, facial numbness, facial weakness, and headaches become more prominent. Physical findings other than hea...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1983-11-01 00:00:00
abstract：OBJECTIVE:To derive risk models for percutaneous coronary intervention (PCI) outcomes from clinical and laboratory variables available before the procedure so they can be used for preprocedure risk stratification. PATIENTS AND METHODS:Using the Mayo Clinic registry, we analyzed 9035 PCIs on 7640 unique patients from J...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/82.6.701
更新日期：2007-06-01 00:00:00
abstract：:B-cell chronic lymphocytic leukemia (B-CLL) is a relatively indolent hematologic malignant disease that, despite a good response to nonaggressive orally administered chemotherapy, currently remains incurable. The overall median duration of survival is more than 5 years, and the presence of anemia or thrombocytopenia a...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/s0025-6196(12)61551-1
更新日期：1992-04-01 00:00:00
abstract：OBJECTIVE:To present the epidemiologic and clinical features of renovascular disease and discuss various diagnostic approaches. DESIGN:We describe the findings in patients with fibromuscular dysplasia or atherosclerotic disease of the renal arteries and review pertinent studies from the literature. RESULTS:Renovascul...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/s0025-6196(12)65771-1
更新日期：1994-12-01 00:00:00
abstract：:There is overwhelming evidence that racial and ethnic minorities face multiple health care disparities. Recognizing and addressing cultural and religious/spiritual (RS) values is a critical aspect of providing goal-concordant care for patients facing a serious illness, especially at the end of life. Failure to address...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/j.mayocp.2016.08.024
更新日期：2017-01-01 00:00:00
abstract：:The ventriculoatrial shunt (VAS) was developed to control hydrocephalic syndromes effectively. Several complications, however, have been described after the procedure. One of the most serious consequences is the development of severe pulmonary hypertension attributed to multiple and recurrent pulmonary embolization ca...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/s0025-6196(12)60069-x
更新日期：1993-12-01 00:00:00
abstract：:Breast cancer is the most common noncutaneous malignancy among every major ethnic group of women in the United States. Anthracyclines and taxanes are the most active and widely used chemotherapeutic agents for breast cancer, but the increased use of these agents at an early stage of disease often renders tumors resist...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/S0025-6196(11)60585-5
更新日期：2009-06-01 00:00:00
abstract：OBJECTIVE:To investigate the predictors of monoclonal gammopathy of undetermined significance (MGUS) by considering not only the initial features but also the pattern of evolution of the M protein during the first years after diagnosis. PATIENTS AND METHODS:This study consisted of 359 patients diagnosed as having MGUS...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/82.4.428
更新日期：2007-04-01 00:00:00
abstract：:Genitourinary syndrome of menopause (GSM), previously known as atrophic vaginitis or vulvovaginal atrophy, affects more than half of postmenopausal women. Caused by low estrogen levels after menopause, it results in bothersome symptoms, including vaginal dryness, itching, dyspareunia, urinary urgency and increased fre...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/j.mayocp.2017.08.019
更新日期：2017-12-01 00:00:00
abstract：:Breast cancer is the most common cancer among women in the United States, with an estimated 200,000 new cases diagnosed annually. A multidisciplinary focus that entails prevention, diagnosis, and treatment has led to significant strides in the reduction of breast cancer incidence and mortality. Additionally, breast ca...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.4065/82.8.999
更新日期：2007-08-01 00:00:00
abstract：:The prevalence of skin and soft tissue infections (SSTIs) has been increasing in the United States. These infections are associated with an increase in hospital admissions. Hospitalists play an increasingly important role in the management of these infections and need to use hospital resources efficiently and effectiv...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/j.mayocp.2014.04.018
更新日期：2014-10-01 00:00:00
abstract：:An inexpensive and reproducible model to help in developing the technical skills for, and to investigate experimentally, a microvascular anastomosis resembling the superficial temporal-middle cerebral artery bypass is described. The model is used to illustrate the important principles of microvascular surgery. Using a...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1976-05-01 00:00:00
abstract：OBJECTIVE:To determine the effect of psychologic distress, measured with a commonly used screening questionnaire, on 6-month morbidity and rehospitalization costs in coronary patients. DESIGN:Psychologic distress was determined by screening with the Symptom Checklist-90--Revised (SCL-90-R) self-report inventory during...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/70.8.734
更新日期：1995-08-01 00:00:00
abstract：OBJECTIVE:To analyze the relationship of ideal cardiovascular health to disease-specific death. PATIENTS AND METHODS:We used data from the Aerobics Center Longitudinal Study from October 9, 1987, to March 3, 1999, to estimate the prevalence of ideal cardiovascular health in 11,993 individuals (24.3% women) and to exam...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2012.07.015
更新日期：2012-10-01 00:00:00
abstract：:A case is reported in which a herpes zoster infection caused recurrence of phantom limb pain in a man whose left arm had been amputated 7 years previously. It is, to our knowledge, the first such case reported, and it shows the importance of peripheral mechanisms in the generation of phantom limb pain. ...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1978-05-01 00:00:00
abstract：:Tinnitus, a common complaint, reportedly affects more than 37 million Americans. Most often, it is associated with a sensorineural hearing loss in the high-frequency range. Tinnitus, however, is a symptom and not a disease. Complacency about this symptom complex may cause physicians to overlook a severe underlying pat...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/s0025-6196(12)60521-7
更新日期：1991-06-01 00:00:00
abstract：:Dyspnea is a common symptom that is difficult to define and can result from a wide variety of causes. This complex sensation that arises from multiple stimuli involves both subjective perceptions and objective reactions. In the assessment of patients with dyspnea, use of a systematic approach to determine the precipit...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/s0025-6196(12)61344-5
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVE:To verify whether absolute monocyte count (AMC) and lymphocyte- monocyte ratio (LMR) at diagnosis are valid prognostic parameters in classical Hodgkin lymphoma (cHL). PATIENTS AND METHODS:Data were collected from 1450 patients with cHL treated in Israel and Italy from January 1, 1988, through December 31, 20...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2015.03.025
更新日期：2015-06-01 00:00:00
abstract：:A 4 1/2-year-old girl is described in whom the portal vein is absent and the venous return from the gastrointestinal tract, spleen, and pancreas is through the left renal vein into the inferior vena cava. She had a hepatoblastoma, which was treated surgically by right hepatic lobectomy. Regeneration occurred in the re...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:Plasma concentration of brain natriuretic peptide (BNP), as measured by the Triage BNP Test, is approved by the Food and Drug Administration to aid in the diagnosis of heart failure. This diagnostic test is available in many institutions. The purpose of this article is to help the physician know the appropriate time t...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.4065/78.4.481
更新日期：2003-04-01 00:00:00
abstract：OBJECTIVE:To estimate the 3-month cumulative incidence of thromboembolism (TE), bleeding, and death among consecutive patients with nonvalvular atrial fibrillation (AF) who were receiving long-term anticoagulation therapy and were referred to the Thrombophilia Center at Mayo Clinic for periprocedural anticoagulation ma...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/83.6.639
更新日期：2008-06-01 00:00:00
abstract：:Total respiratory resistance (Rrs) was studied by the forced oscillation technique at a frequency of 3 cps in 76 normal subjects (36 men, 40 women), ages 21 to 64 years. Slopes (equivalent to specific conductance) assuming a linear relationship with zero intercept between 1/Rrs and thoracic gas volume (TGV) were compu...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：:Seven vertex-positive potentials--the brainstem auditory response--can be recorded from the human scalp within 10 milliseconds of an appropriate acoustic stimulus. The first of these potentials is generated in the acoustic nerve, the third in the pons, and the fifth in the midbrain. Measurement of the relative latenci...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1977-12-01 00:00:00
abstract：:Three patients who had coryneform bacterial endocarditis affecting a prosthetic valve are presented and 64 case reports are reviewed. Diagnostic difficulties occur because coryneform bacteria often are fastidiuos, with long incubation periods, and often contaminate blood cultures. Although some coryneform bacteria are...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：
更新日期：1977-04-01 00:00:00
abstract：:Benign prostatic hyperplasia (BPH), a nonmalignant neoplasm of the prostatic epithelial and stromal tissue, occurs commonly in elderly men. The "gold standard" of care for symptomatic BPH has been and remains transurethral resection of the prostate. This operation, however, like any surgical procedure, has associated ...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/s0025-6196(12)60603-x
更新日期：1993-07-01 00:00:00
abstract：:Coronary artery fistulas are infrequently encountered vascular communications that are either congenital or due to cardiac trauma. Most patients with these anomalies are asymptomatic, but late complications can occur and include congestive heart failure, myocardial ischemia, arrhythmias, and endocarditis. Therefore, m...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.4065/71.1.37
更新日期：1996-01-01 00:00:00
abstract：OBJECTIVE:To compare the indications for hospital admission between current, former, and never smokers and to compare their costs per hospital admission, testing the hypothesis that the cost per hospital admission would be higher for smokers than for former and never smokers. PATIENTS AND METHODS:This study used a ret...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章
doi：10.1016/j.mayocp.2018.02.022
更新日期：2018-08-01 00:00:00
abstract：:Cataract operations are commonly performed in either a primary-care or a tertiary-care center. A plethora of information (some of which is unfounded) has been disseminated in the lay news media about the advances in the surgical techniques of cataract removal. This article reviews some of the recent concepts about the...
journal_title：Mayo Clinic proceedings
pub_type： 杂志文章,评审
doi：10.1016/s0025-6196(12)61494-3
更新日期：1984-08-01 00:00:00
