Abstract：
UNLABELLED:Labour induction is frequently indicated in women with an unfavourable cervix. Oxytocin and prostaglandins are the most common drugs used for labour induction. Induction of labour with prostaglandins offers the advantage of promoting both cervical ripening and myometrial contractility. The purpose of the study was to evaluate the safety and efficacy intravaginal administration prostaglandin E1 methyl analogue, misoprostol in cervical ripening and induction of labour in term pregnancy and in women with unfavourable cervix (Bishop score < = 4). The approval for this study was given by the Board of Medical Ethics, University Medical School of Lublin in Poland. MATERIALS AND METHODS:64 women with indication for termination of pregnancy received either misoprostol (Cytotec-Searle) vaginally (group M, n = 30) or intravenous drip infusion of oxytocin(group Ox, n = 34). We evaluated profile of the studied women (gravidity, weight, height, maternal age, gestational age), effectiveness and safety of the misoprostol and need for oxytocin administration in group M, start of induction-to-active labour interval (contractions), start of induction-to-vaginal delivery interval, hyperstimulation syndrome, delivery within 24 hours of drug application and caesarean section rate. Before starting labour induction a Bishop score was obtained. Statistical analysis was performed. Baseline and outcome variables were tested with student's t-test and c2 analysis. We needed p < 0.05 for statistical significance. RESULTS:There were no differences in the patient profiles (gravidity, weight, height, maternal age, gestational age) between groups except the score of cervical ripening. The Bishop score before induction was lower in group M. The interval between the initiation of induction to active labour was shorter in the misoprostol group (334.23 +/- 126.35 versus 610.00 +/- 352.14 minutes). The mean time between the initiation of induction to delivery was shorter in group M (707.69 +/- 341.15 +/- versus 1025.77 +/- 369.16 minutes). These differences were statistically significant. 28 (93.33%) patients in the misoprostol group delivered within 24 hours compared with 24 (70.59%) women in the oxytocin group. 8 patients in the misoprostol group and 8 patient in the oxytocin group had caesarean section. Labor induction was successful in 30 (100%) women in the misoprostol group compared with 24 (70.59%) patients in the group Ox. CONCLUSIONS:Intravaginal misoprostol is an effective, easy to use and cheap drug for the induction of labour, especially for cervical ripening in women with unfavourable cervix (Bishop score < = 4).
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Leszczyńska-Gorzelak B,Laskowska M,Oleszczuk Jkeywords:
subject
Has Abstractpub_date
1999-12-01 00:00:00pages
881-9issue
12eissn
0017-0011issn
2543-6767journal_volume
70pub_type
临床试验,杂志文章abstract：OBJECTIVES:The aim of the study was to investigate to what extent sweeping of the membranes contributes to cervical shortening and if cervical shortening is related to the time to onset of labor and duration of the active phase of labor METHODS:This prospective randomized clinical trial was performed at Baskent Univer...
journal_title：Ginekologia polska
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2014-09-01 00:00:00
abstract：:The aim of the work were changes of serum ferritin and iron concentrations in women with leiomyoma of the uterus treated surgically. We took the growth of the leiomyomatous uterus under concern. We observed the lower serum ferritin and iron concentrations before the surgical treatment, and the correlation with the gro...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：:Three different variants of biologically agressive cervical cancers, such as: basaloid carcinoma, glassy cell carcinoma and small cell endocrine carcinoma, have been reported. Hematoxylin and eosin, periodic acid-Schiff and immunohistochemical stains were used. The course of disease and aplication of treatment has bee...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2007-09-01 00:00:00
abstract：:Higher rate of morbidity and mortality has been noted in tween pregnancies comparing to singleton pregnancies. Early ultrasound investigation between 6 and 12 week of gestation is useful in determining time of gestation, amniocity and chorionicity (adequacy of diagnosis ranged from 95 to 100%). Determining of chorioni...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2000-11-01 00:00:00
abstract：OBJECTIVES:The purpose of the study was to check the conformity of diagnosis based on macroscopic hysteroscopy image with the respective pathology report. MATERIALS AND METHODS:Study population consisted of 160 patients aged 45-86 years, with abnormal uterine bleeding or abnormal ultrasonographic image of endometrium....
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to determine whether anhydramnios affected the duration of medical abortion in cases with various indications as compared to cases with normal amniotic fluid volume. MATERIAL AND METHODS:Patients who were admitted to our clinic because of medical abortion between January 2010-Decemb...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0058
更新日期：2016-01-01 00:00:00
abstract：:The expression of c-MYC gene has been detected by using the method of in situ hybridization. It has been detected mainly in glandular cells but also in stromal cells in atypical endometrial hyperplasia in women after menopause regardless of their age. A similar expression has been found to occur in nonatypical case of...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-11-01 00:00:00
abstract：:The paper concerns the treatment results of 113 women with PCO-S by laparoscopic (102) and microlaparoscopic (11) ovarian electrocautery. All of them were qualified for operation on the basis of the following criteria: menstrual cycle disturbances (oligo-/amenorrhoea), anovulation, hirsutism, obesity, LH/FSH ratio > 2...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2001-08-01 00:00:00
abstract：:Authors of this research present 3 cases of struma ovarii diagnosed in postoperative histopathological examination in years 1994-1997. The first one was accidentally discovered during examination of a woman in menopausal period, the second was a case of 39-years old woman with hyperthyroidism and struma parenchymatoso...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：:Treatment of the malignant ovarian tumors remains challenging. Some of the reasons are as follows: lack of effective screening technique, usually asymptomatic early stages of the disease, which effects in detecting the disease in advanced stage, and eventually poor prognosis. Treatment of the relapse remains palliativ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/59268
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVES:Histones are involved in process of proliferation and differentiation of the cells. In many lesions the expression of mRNA of histones is a marker of proliferation. The expression of kinin receptors B1 and B2 coexist with inflammatory processes, but in some studies the expression of these receptors was found...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2002-11-01 00:00:00
abstract：:Triploidy is one of the most common chromosomal numerical aberrations, resulting usually from one out off two main mechanisms: aberrant segregation of chromosomes during meiosis or from the fertilization of one egg by two sperms. Triploidy usually causes prenatal death. In present paper the methods of non-invasive and...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:Scientific journals are ranked and evaluated to measure their relative importance and influence on science within a specific field. One of the tools most widely used to evaluate and compare journals is the Thomson Reuters Impact Factor In Poland a specific value of a scientist's Impact Factor is required for academic ...
journal_title：Ginekologia polska
pub_type： 社论
doi：
更新日期：2011-08-01 00:00:00
abstract：:Sensibility and specificity of transvaginal ultrasonography and diagnostic hysteroscopy were compared in 211 infertile women. Examinations were performed between 1996-2000 in I-st Department of Obstetrics and Gynecology Warsaw Medical University--Poland. Comparing results we concluded high compatibility of transvagina...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVES:I am presenting a new and personal method of surgical treating a uterovaginal prolapses using vaginal approach. MATERIAL AND METHODS:From 30th July to 30th November 2004, 12 patients between the ages of 40 and 83 years were operated on using the RFV method. The RFV Surgical Method is a new, inexpensive and ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-02-01 00:00:00
abstract：:We have analysed 6 cases of twin pregnancies with vertex presentation of the first foetus. In this cases after delivery of the first twin by vaginal route caesarean, section was made. Caesarean section of the second twin was made because of: transversal presentation with fetal distress syndrom (four cases), umbilical ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-11-01 00:00:00
abstract：:The are shown the expediency of prophylactic antibiotics administration during cesarean section. The investigations contained 32 pregnant women who were given intravenously augmentin in dose of 1.2 g. The control group was made from 31 pregnant women who do not received antibiotic. In both group cesarean section was p...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:An increase in alpha-amylase activity with parallel decrease in glucose concentration in amniotic fluid is observed during pregnancy. This interdependence is a theoretical basis for using an alpha-amylase/glucose index in fetal maturity evaluation. The aim of the study was to investigate usefulness of the alpha-amylas...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-09-01 00:00:00
abstract：:Diagnostic microlaparoscopy was performed on 30 patients aged 17-41. Indications++ for these procedures were: sterility (17), tumor of the ovary (5), endometriosis (3), uterine myoma (2), pelvic pain syndrome++ (1), carcinoma of the ovary--second look procedures (1), operative hysteroscopy (1). During these procedures...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-08-01 00:00:00
abstract：:The ovarian hyperstimulation syndrome (OHSS) is still a difficult diagnostic and therapeutic problem. OHSS is associated with significant hypertrophy of the ovaries associated with the loss of the intravascular fluid to the third space which results in hypovolaemia, oliguria, electrolyte imbalance, and a rise in haema...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2006-11-01 00:00:00
abstract：:The knowledge of ovarian physiopathology and the employing of modern diagnostic methods (ultrasonography, laparoscopy) allow to avoid to operate patients with functional cysts. Girls and young women should be evaluated individually for ovarian surgical procedures. The operative treatment should be so conservative as p...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：OBJECTIVES:In our study, we tried to investigate the determinants of women's choices about contraception with the aim of discovering whether or not there is a difference in their preferences before and after consultation with a gynaecologist. MATERIAL AND METHODS:A total of 1058 women were enrolled. They were given de...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2017.0115
更新日期：2017-01-01 00:00:00
abstract：:Family history of ovarian cancer has been regarded as the most important risk factor in developing this type of tumor. Recent identification of cloning of specific tumor suppressor genes responsible for hereditary ovarian cancer syndromes, resulted in the surge of enthusiasm and optimism regarding the practical applic...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2003-07-01 00:00:00
abstract：OBJECTIVE:Angiogenesis in malignant tumors is a prognostic factor associated with tumor growth and metastasis. The aim of the research was: determination of the angiodensity rate in two immunohistochemical techniques, estimation of the value of the examined parameter at different stages of clinical progression and hist...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:The concentration of N-terminal propeptide of type III procollagen (PIIINP) in umbilical cord serum was estimated in preterm and term newborns. The mean concentration of PIIINP was significantly higher in preterm infants, despite their lower body mass. This indicates higher rate of collagen biosynthesis in early gesta...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：:Not all pregnant women with gall bladder stones can be treated conservatively--some of them require surgery. The main indications for cholecystectomy are the following: repeated episodes of biliary colic and acute cholecystitis. There is no data indicating which moment during the pregnancy may be the safest to perform...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2008-11-01 00:00:00
abstract：:In 39 full-term neonates aged from 1 to 7 days of life, among them 24 with perinatal risk factors and 15 healthy as the control group, immunophenotyping of CD3+ and CD25+ cells using Becton Dickinson flow cytometer and monoclonal antibodies and CD3+ and CD25+ was performed. It was stated, that the mean relative and ab...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：:Literature concerning the changes caused in lipids and protein metabolism in women using gestagen preparations for contraceptive purposes is surveyed. The level of metabolic changes was found to be related to the estrogen content of the preparation. Lipid metabolism changes are in the form of increases in the total ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1976-07-01 00:00:00
abstract：:The aim of the work is to present regenerative medicine achievement as an alternative SUI treatment and the variety of injected cells type as well as injection techniques itself with the analysis of their quality and possible the mechanism in which they reduce urinary incontinence symptoms. For over a decade numerous ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/60973
更新日期：2016-01-01 00:00:00
abstract：:We present a case of vaginal vault prolapse after hysterectomy associated with cystocoele with central and lateral defect and stress urinary incontinence, that was treated surgically with employment of sacrospinous colpopexy through anterior approach (from paravesical space), combined with anterior colporrhaphy by dou...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
