Abstract:
:Family history of ovarian cancer has been regarded as the most important risk factor in developing this type of tumor. Recent identification of cloning of specific tumor suppressor genes responsible for hereditary ovarian cancer syndromes, resulted in the surge of enthusiasm and optimism regarding the practical application of genetic information. Many investigators believe that natural history of hereditary ovarian may significantly differ from sporadic cases. Some independent findings have shown that serous adenocarcinoma was the most frequent histological type in hereditary ovarian cancer patients, whereas the mucinous and the borderline were underrepresented in this group. Also, patients with hereditary ovarian cancer tend to develop the disease at younger than expected age. At the present moment, it remains unknown if environmental/lifestyle factors play a role in penetrance and expression of specific tumor suppressor genes in mutation carriers. The era of molecular genetics has raised hopes not only for a better understanding of biology and natural history of hereditary ovarian tumors but also a rapid breakthrough in prevention and management of this disease.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Majdak E,Debniak J,Emerich Jkeywords:
subject
Has Abstractpub_date
2003-07-01 00:00:00pages
557-64issue
7eissn
0017-0011issn
2543-6767journal_volume
74pub_type
杂志文章,评审abstract::Cyclopia is a deformation of the facial skeleton with one eye orbit formed in the place where both eyes should be present. As a result of hypoplasia there is absence (hypothesized loss) of central nervous system structures. Teratogenic factors leading to the occurrence of this anomaly may include irregular cholesterol...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVES:Surgical site infection (SSI) following gynecologic oncology surgery is a severe problem for both patient and surgeon in terms of increasing morbidity, length of hospital stay, anxiety, and costs. In this prospective, randomized, controlled study we investigated the effect of subcutaneous rifampicin and povi...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.a2020.0134
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:In recent years, much attention has been given to infants born prematurely, at 34 0/7 to 36 6/7 weeks of gestation (WG), which have been classified as 'late preterm'. Neonates from that subgroup are less physiologically and metabolically mature than term infants. The aim of the study was to determine whether...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.2016.0092
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:To evaluate data regarding neonatal mortality and short term morbidity among iatrogenic late preterm (ILP) and spontaneous late preterm (SLP) twin births, and to estimate whether medical interventions - induction of labor in this particular context, are associated with better or poorer outcomes. MATERIAL AN...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.17772/gp/1600
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVES:According to the literature the frequency of twins is increasing due to technics af assisted reproduction. Many complications of pregnancy and delivery are more likely to develop during multiple pregnancy. DESIGN:Aim of the study was to analyze labour and delivery in multiple pregnancy and assess the neonat...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2005-03-01 00:00:00
abstract::EPH-gestosis is accompanied by an extensive remodeling of the extracellular matrix of Wharton's jelly. The gelatinolytic and proteolytic activities were measured. A decrease in gelatinolityc activity and an increase in proteolytic activity in EPH-gestosis were observed. The decrease in gelatinase activity in EPH-gesto...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2002-05-01 00:00:00
abstract::We report an unusual case of adenomyosis with asymptomatic thoracic endometriosis. A 30-year old woman had a history of nephroblastoma, two missed abortions and one childbirth by caesarean section. The pregnancy was complicated with asymmetric fetus hipotrophy. Two years after delivery she had assessments for dysmenor...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::The term hypertension in pregnancy stands either for a high blood pressure, which has already developed before pregnancy (i.e., chronic hypertension in pregnancy), or for a pregnancy-associated disease (i.e., pregnancy-induced hypertension). Each form of hypertension may be an isolated phenomenon or constitute a part ...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2002-09-01 00:00:00
abstract::Oral anticoagulants are contraindicated during pregnancy, especially during the I and III trimester, therefore heparin is recommended instead. We used fraxiparine s.c. once daily in prophylactic doses in 6 patients during pregnancy and labor (mean time of prophylaxis 6.5 months). Two of them received fraxiparine becau...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract::Endometrial cancer is one of the most frequently diagnosed malignant neoplasms among women. In Poland, it is in the fourth place in terms of incidence. The highest morbidity concerns women aged 50-70 years, however it may also appear in women in their reproductive period. Endometrial cancer concerns about 3% of premen...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2012-03-01 00:00:00
abstract::In 39 full-term neonates aged from 1 to 7 days of life, among them 24 with perinatal risk factors and 15 healthy as the control group, immunophenotyping of CD3+ and CD25+ cells using Becton Dickinson flow cytometer and monoclonal antibodies and CD3+ and CD25+ was performed. It was stated, that the mean relative and ab...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract:DESIGN:Although an association between subclinical intrauterine infection and preterm birth is well established, there is conflicting evidence regarding the benefits of antibiotic administration in women in preterm labor. OBJECTIVES:We attempted to determine the effect of antibioticotherapy in mothers on congenital ne...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract:UNLABELLED:The aim of the study was to evaluate antioxidant system activity and lipid peroxidations products as markers of oxidative stress in the cord blood of newborns delivered to mothers with diabetes type G1 in comparison to healthy pregnant women. MATERIALS AND METHODS:We examined 10 healthy and 10 diabetic moth...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Ductus venosus is the fetal blood vessel connecting the abdominal portion of the umbilical vein with the inferior vena cava. Numerous studies have confirmed the important role of this vessel in fetal circulation. There are, however cases when finding the ductus venosus during an ultrasound examination is imp...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.17772/gp/1623
更新日期:2013-08-01 00:00:00
abstract::Concentrations of glucose, bilirubin, H+ ions, estriol, HPL were determined in the samples of amniotic fluid from post term and near term pregnancies. Investigated group consisted of samples taken between 42-43 week of gestation, control group between 38-40 week. In both groups biochemical tests of pulmonary maturatio...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1995-05-01 00:00:00
abstract::A case of a 43-year-old multipara in 36th week of pregnancy with a duplicate uterus and uterine myoma with 15 centimeters diameter has been presented in the article. The aim of the study was to present her obstetric history, course of pregnancy and delivery mode. ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVES:Objective was to examine the relationship of obesity, body fat distribution fasting plasma insulin concentrations and triglycerides of pro-thrombotic and fibrinolitics factors in pre and postmenopausal women. MATERIAL AND METHODS:We assessed 24 (13 nonobese and 11 obese) postmenopausal and 44 (15 obese and ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVES:Triplet pregnancies have higher perinatal morbidity and mortality rates than singleton pregnancies. In modern perinatology computer cardiotocography is one of the best methods of fetus state assessment. DESIGN:The research was based on computer analysis of cardiotocograph printouts. MATERIALS AND METHODS:T...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2006-10-01 00:00:00
abstract:DESIGN:The aim of our study was a currently clinical analysis of menarche. MATERIALS AND METHODS:The mean age of menarche was investigated in 4497 girls between 1975-1997 69 girls were examined throughly in the course of menarche. Age at menarche, body weight, height, body mass index (BMI), some of the hormones and ul...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00
abstract::127 pregnant patients between 20 and 37 week of gestation were studied. Cervical estimation was done by using transvaginal ultrasonography. An accurate estimation was possible in all investigation patients. Statistically significant distinctions in uterine cervical length during pregnancy progress were noticed (p < 0....
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1994-08-01 00:00:00
abstract:OBJECTIVES:Ovarian reserve is the main factor influencing the efficacy of infertility treatment. Currently the anti- Müllerian hormone is the main indicator of the ovarian reserve and has a wide spectrum of clinical importance. It achieved a high clinical value right after the introduction of the first commercial AMH a...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to evaluate the concentrations of kynurenic acid (KYNA) in blood and urine during the normal pregnancy. MATERIALS AND METHODS:Under the study were 37 pregnant women. Level of KYNA was measured by high performance liquid chromatography (HPLC). RESULTS:The KYNA concentration in blood...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00
abstract::Adnexal torsion belongs to the group of urgent cases in gynecology Early diagnosis and management can prevent the loss of an ovary and the Fallopian tube. The case of the 14.5-year-old girl was described by the authors. The symptoms were moderate and caused diagnostics problems. During clinical assessment current lite...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract::The first results of laser therapy in treatment of condylomata acuminata of male reproductive organs are reported. Between November 1991 and December 1993 in Department of Reproduction, Institute of Gynecology and Obstetrics, Karol Marcinkowski University School of Medical Sciences, Poznań in nine patients with condyl...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVES:Human papillomavirus (HPV) ranks the first cause of cervical cancer. Cervical cancer has high prevalence rates in women around the world. The HPV-E7 oncoprotein is expressed in cervical cancer and is a target of developing immunotherapies against HPV-associated tumors. However, the antigenicity of this prote...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.2020.0055
更新日期:2020-01-01 00:00:00
abstract::Authors had retrospectively analyzed basic exponents of perinatal care of 256 pregnant diabetic woman in years 1993-1998 hospitalized and delivered in Clinic of Obstetrics and Gynaecology in the town of Bytom. Our results were very similar to the other of Referent Centres Of Technical Methods Bank Used in Diagnostic a...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1999-10-01 00:00:00
abstract::We present a case of a female neonate, born at 36 weeks of gestation from a monochorionic, diamniotic spontaneous twin pregnancy with congenital epulis, 2.5 cm in size, protruding from the oral cavity. Histopathology revealed a typical granular cell lesion. The other twin, also female, was prenatally diagnosed with co...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.17772/gp/1633
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:The two functions of the lower urinary tract are the filling/storage and emptying. Similarly lower urinary tract symptoms can be subdivided. DESIGN:The aim of the study was the estimation of usefulness of present complaints-voiding history in diagnosis of lower urinary tract dysfunctions. MATERIAL AND METH...
journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:2001-03-01 00:00:00
abstract::To make use of antigonadotropin and antiproliferating action of the synthetic analogs of GnRH there was applied this decapeptide in 33 patients with ovarian cancer who were treated traditionally by chemotherapeutics PAC and radiotherapy. The monitoring of treatment was supported on the clinical opinion of the whole an...
journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVES:Recent studies have demonstrated that disorders of bone metabolism, which is regulated by RANK/RANKL/OPG signaling pathway, are the cause of osteoporosis. The aim of the study was to investigate the distribution of genotypes of the RANK 575C>T and RANKL -643C>T polymorphisms and to analyze their relationship...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.2016.0014
更新日期:2016-01-01 00:00:00