Abstract:
:Acquired pure megakaryocytic aplasia is a rare disorder defined by severe thrombocytopenia with no other hematologic abnormalities and absent, or severely decreased marrow megakaryocytes. The etiology may be immune suppression of megakaryocyte development. Two patients are described who both responded rapidly to a combination of antithymocyte globulin and cyclosporine and who remain in remission 13-20 months after discontinuation of cyclosporine. This regimen is well described for treatment of aplastic anemia and may also be effective for acquired pure megakaryocytic aplasia.
journal_name
Am J Hematoljournal_title
American journal of hematologyauthors
Leach JW,Hussein KK,George JNdoi
10.1002/(sici)1096-8652(199910)62:2<115::aid-ajh10keywords:
subject
Has Abstractpub_date
1999-10-01 00:00:00pages
115-7issue
2eissn
0361-8609issn
1096-8652pii
10.1002/(SICI)1096-8652(199910)62:2<115::AID-AJH10journal_volume
62pub_type
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