Abstract:
:Advances in infant cardiac surgery have resulted in a dramatic decline in mortality rates; however, neurological morbidity remains an important concern. The effectiveness of a number of interventional strategies to prevent or minimize brain injury during open heart surgery are currently being investigated. This article provides an overview of two approaches: (1) interventions to enhance intraoperative cerebral oxygenation so as to prevent hypoxic-ischemic insults, and (2) the application of cerebral rescue therapies to attenuate the cascade of brain injury. Infant cardiac surgery provides a controlled environment in which to apply these neuroprotective approaches, so as to optimize the quality of life of these vulnerable children.
journal_name
Semin Pediatr Neuroljournal_title
Seminars in pediatric neurologyauthors
du Plessis AJ,Johnston MVdoi
10.1016/s1071-9091(99)80047-3keywords:
subject
Has Abstractpub_date
1999-03-01 00:00:00pages
55-63issue
1eissn
1071-9091issn
1558-0776pii
S1071-9091(99)80047-3journal_volume
6pub_type
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
pub_type: 杂志文章,评审
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journal_title:Seminars in pediatric neurology
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journal_title:Seminars in pediatric neurology
pub_type: 杂志文章,评审
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journal_title:Seminars in pediatric neurology
pub_type: 杂志文章,评审
doi:10.1053/spen.2001.23456
更新日期:2001-03-01 00:00:00
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journal_title:Seminars in pediatric neurology
pub_type: 杂志文章
doi:10.1016/j.spen.2011.05.006
更新日期:2011-06-01 00:00:00
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journal_title:Seminars in pediatric neurology
pub_type: 杂志文章
doi:10.1016/j.spen.2010.04.002
更新日期:2010-06-01 00:00:00
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journal_title:Seminars in pediatric neurology
pub_type: 杂志文章,评审
doi:10.1016/j.spen.2011.06.002
更新日期:2011-09-01 00:00:00
abstract::Neonatal neurocritical care is an evolving subsubspecialty whose goal is to implement neuroprotective care strategies, continuous bedside monitoring of neurologic function, and therapies in order to reduce the risk of neurologic injury and improve long-term neurodevelopmental outcomes in neonates who require intensive...
journal_title:Seminars in pediatric neurology
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