The Maximum Bite Force for Treatment Evaluation in Severely Affected Adult SMA Patients-Protocol for a Longitudinal Study.

abstract：:Background: Early imaging-based treatment response assessment of brain metastases following stereotactic radiosurgery (SRS) remains challenging. The aim of this study is to determine whether early (within 12 weeks) intratumoral changes in interstitial fluid pressure (IFP) and velocity (IFV) estimated from computationa...

journal_title：Frontiers in neurology

authors： Swinburne N,LoCastro E,Paudyal R,Oh JH,Taunk NK,Shah A,Beal K,Vachha B,Young RJ,Holodny AI,Shukla-Dave A,Hatzoglou V

更新日期：2020-05-28 00:00:00

abstract：:In a recent clinical report, return of the tendon stretch reflex was demonstrated after spinal cord surgery in a case of total traumatic brachial plexus avulsion injury. Peripheral nerve grafts had been implanted into the spinal cord to reconnect to the peripheral nerves for motor and sensory function. The dorsal root...

journal_title：Frontiers in neurology

authors： James ND,Angéria M,Bradbury EJ,Damberg P,McMahon SB,Risling M,Carlstedt T

更新日期：2017-07-24 00:00:00

abstract：:Objective: To report a rare case of brainstem encephalitis with low-titer acetylcholine receptor antibodies mimicking myasthenia gravis. Methods: The patient was investigated with repeated brain MRI, CSF examination, repetitive nerve stimulation, thoracic CT, and serologic screening. Our patient passed away and finall...

journal_title：Frontiers in neurology

authors： Ayzenberg I,Ellrichmann G,Schroeder C,Tönges L,Klasing A,Pappa V,Brück W,Gold R

更新日期：2019-08-02 00:00:00

abstract：:Background: Neurofilament light chain (NFL) was believed to be a promising biomarker for the diagnosis of Amyotrophic lateral sclerosis (ALS) and disease burden evaluation. Objective: To determine the serum NFL level and its clinical relevance, including its association with disease severity [evaluated by the ALS Func...

journal_title：Frontiers in neurology

authors： Sugimoto K,Han Y,Song Y,Gao Y

更新日期：2020-12-03 00:00:00

abstract：:Aims: To examine trajectories of employment probability up to 10 years following moderate-to-severe traumatic brain injury (TBI) and identify significant predictors from baseline socio-demographic and injury characteristics. Methods: A longitudinal observational study followed 97 individuals with moderate-to-severe TB...

journal_title：Frontiers in neurology

authors： Howe EI,Andelic N,Perrin PB,Røe C,Sigurdardottir S,Arango-Lasprilla JC,Lu J,Løvstad M,Forslund MV

更新日期：2018-12-05 00:00:00

abstract：:Background: For the preoperatively often required confirmation of clinically defined carpal tunnel syndrome (CTS), sensory as well as motor nerve conduction studies can be applied. The aim of this study was to test the sensitivity of specific motor nerve conduction tests in comparison with, as well as in addition to, ...

journal_title：Frontiers in neurology

authors： Kasius KM,Claes F,Verhagen WIM,Meulstee J

更新日期：2019-03-14 00:00:00

abstract：:Background: Disorders of consciousness are challenging to diagnose, with inconsistent behavioral responses, motor and cognitive disabilities, leading to approximately 40% misdiagnoses. Heart rate variability (HRV) reflects the complexity of the heart-brain two-way dynamic interactions. HRV entropy analysis quantifies ...

journal_title：Frontiers in neurology

authors： Riganello F,Larroque SK,Bahri MA,Heine L,Martial C,Carrière M,Charland-Verville V,Aubinet C,Vanhaudenhuyse A,Chatelle C,Laureys S,Di Perri C

更新日期：2018-09-12 00:00:00

abstract：BACKGROUND:Before implementation in clinical practice, biomarker assays need to be thoroughly analytically validated. There is currently a strong interest in implementation of the ratio of amyloid-β peptide 1-42 and 1-40 (Aβ42/Aβ40) in clinical routine. Therefore, in this study, we compared the analytical performance o...

journal_title：Frontiers in neurology

authors： van Waalwijk van Doorn LJC,Kulic L,Koel-Simmelink MJA,Kuiperij HB,Versleijen AAM,Struyfs H,Twaalfhoven HAM,Fourier A,Engelborghs S,Perret-Liaudet A,Lehmann S,Verbeek MM,Vanmechelen EJM,Teunissen CE

更新日期：2017-07-03 00:00:00

abstract：OBJECTIVE:To provide a systematic review of the clinical and radiological features of lesion-induced central positional nystagmus (CPN) and identify salient characteristics that differentiate central from peripheral positional nystagmus (PN). METHODS:Systematic literature search according to the preferred reporting it...

journal_title：Frontiers in neurology

authors： Macdonald NK,Kaski D,Saman Y,Al-Shaikh Sulaiman A,Anwer A,Bamiou DE

更新日期：2017-04-20 00:00:00

abstract：:We report a case of spontaneous intracerebral hemorrhage (sICH) due to delta storage pool disease in a 60-year-old female on a serotonin-norepinephrine reuptake inhibitor (SNRI). Increased susceptibility to SNRI-effects on hemostasis was due to a genetic disposition mediated by a polymorphism of the SLC6A4 gene coding...

journal_title：Frontiers in neurology

authors： Leibetseder A,Wagner J,Tomasits J,Haring HP,Hutterer M,Trenkler J,von Oertzen TJ

更新日期：2019-11-26 00:00:00

abstract：OBJECTIVES:This study aimed to investigate the functional network effects of corpus callosotomy (CC), a well-recognized palliative surgical therapy for patients with Lennox-Gastaut syndrome (LGS). Specifically, we sought to gain insight into the effects of CC on LGS remission, based on brain networks in LGS by calculat...

journal_title：Frontiers in neurology

authors： Liang JG,Lee D,Youn SE,Kim HD,Kim NY

更新日期：2017-09-04 00:00:00

abstract：:Sudden infant death syndrome (SIDS) is the unexplained death, usually during sleep, of a baby younger than 1-year-old. Even though researchers have discovered some factors that may put babies at extra risk, SIDS remains unpredictable up until now. One hypothesis is that impaired cardiovascular control may play a role ...

journal_title：Frontiers in neurology

authors： Zhao F,Li M,Jiang Z,Tsien JZ,Lu Z

更新日期：2016-12-23 00:00:00

abstract：:Hemorrhagic cerebrovascular disease in the pediatric population can have devastating and long-term effects. Progress in the fields of genetics, neuroimaging, pharmacology, and surgical techniques has led to improved diagnosis and management of pediatric cerebrovascular diseases. In this review we discuss the current e...

journal_title：Frontiers in neurology

authors： Guerrero WR,Dandapat S,Ortega-Gutierrez S

更新日期：2020-09-17 00:00:00

abstract：:In the present study, we investigated the genetic variation in a family with acute encephalopathy and retinitis pigmentosa. Nine of 25 people in this family underwent genetic testing. Three family members, namely, the proband and the proband's two sisters, showed symptoms resembling those of meningoencephalitis and si...

journal_title：Frontiers in neurology

authors： You C,Zeng W,Deng L,Lei Z,Gao X,Zhang VW,Wang Y

更新日期：2020-05-05 00:00:00

abstract：:Primary progressive aphasia (PPA) is a neurodegenerative disease characterized by declining language ability. However, the difficulty in defining the central clinical features in its earliest stage and establishing the dynamics of its progression has led to controversy. We report a 71-year-old man with Han language su...

journal_title：Frontiers in neurology

authors： Liu X,He F,Chen Z,Liu P,Peng G

更新日期：2018-02-16 00:00:00

abstract：:Background: Electrical Status Epilepticus in Sleep (ESES) is an epileptic encephalopathy syndrome characterized by infrequent clinical seizures and prominent interictal burden during slow wave sleep associated with cognitive deficits and behavioral dysfunction. Medical treatment with anti-epileptic drugs is often unsu...

journal_title：Frontiers in neurology

authors： Marashly A,Koop J,Loman M,Lee YW,Lew SM

更新日期：2020-01-15 00:00:00

abstract：:Introduction: Novel therapies are needed for the treatment of motion sickness given the inadequate relief and bothersome and dangerous adverse effects of currently approved therapies. Neurokinin-1 (NK1) receptor antagonists have the potential to be effective in improving the symptoms of motion sickness, given the invo...

journal_title：Frontiers in neurology

authors： Polymeropoulos VM,Czeisler MÉ,Gibson MM,Anderson AA,Miglo J,Wang J,Xiao C,Polymeropoulos CM,Birznieks G,Polymeropoulos MH

更新日期：2020-09-29 00:00:00

abstract：:For epileptic patients requiring resective surgery, a modality called stereo-electroencephalography (SEEG) may be used to monitor the patient's brain signals to help identify epileptogenic regions that generate and propagate seizures. SEEG involves the insertion of multiple depth electrodes into the patient's brain, e...

journal_title：Frontiers in neurology

authors： Greene P,Li A,González-Martínez J,Sarma SV

更新日期：2021-01-06 00:00:00

abstract：:Epidemiological associations linking between obstructive sleep apnea and poorer solid malignant tumor outcomes have recently emerged. Putative pathways proposed to explain that these associations have included enhanced hypoxia inducible factor (HIF)-1α and vascular endothelial growth factor (VEGF) cell expression in t...

journal_title：Frontiers in neurology

authors： Almendros I,Martínez-García MÁ,Campos-Rodríguez F,Riveiro-Falkenbach E,Rodríguez-Peralto JL,Nagore E,Martorell-Calatayud A,Hernández Blasco L,Bañuls Roca J,Chiner Vives E,Sánchez-de-la-Torre A,Abad-Capa J,Montserrat JM,Pérez-Gi

更新日期：2018-04-26 00:00:00

abstract：:Rhythmic auditory cueing is a well-accepted tool for gait rehabilitation in Parkinson's disease (PD), which can now be applied in a performance-adapted fashion due to technological advance. This study investigated the immediate differences on gait during a prolonged, 30 min, walk with performance-adapted (intelligent)...

journal_title：Frontiers in neurology

authors： Ginis P,Heremans E,Ferrari A,Dockx K,Canning CG,Nieuwboer A

更新日期：2017-04-06 00:00:00

abstract：BACKGROUND:Public awareness of and attitude toward disease is an important issue for patients. Public awareness of essential tremor (ET) has never been studied. METHODS:We administered a 10-min, 31-item questionnaire to 250 consecutive enrollees. These included three samples carefully chosen to have a potential range ...

journal_title：Frontiers in neurology

authors： Shalaby S,Indes J,Keung B,Gottschalk CH,Machado D,Patel A,Robakis D,Louis ED

更新日期：2016-04-22 00:00:00

abstract：:Background and Purpose: Endovascular thrombectomy improves the functional independence of patients with proximal anterior circulation occlusion. However, a subset of patients fail to benefit from thrombectomy procedures, the reasons for which remain poorly defined. In this study, we investigated whether the effectiven...

journal_title：Frontiers in neurology

authors： Li Z,Chu Z,Zhao S,Ma L,Yang Q,Huang X,Zhou Z

更新日期：2019-05-28 00:00:00

abstract：:Children and adolescent athletes are at a higher risk for concussion than adults, and also experience longer recovery times and increased associated symptoms. It has also recently been demonstrated that multiple, seemingly mild concussions may result in exacerbated and prolonged neurological deficits. Objective assess...

journal_title：Frontiers in neurology

authors： Kiefer AW,Barber Foss K,Reches A,Gadd B,Gordon M,Rushford K,Laufer I,Weiss M,Myer GD

更新日期：2015-11-20 00:00:00

abstract：:Purpose: Whole-brain functional network analysis is an emerging methodology for exploring the mechanisms underlying hepatic encephalopathy (HE). This study aimed to identify the brain subnetwork that is significantly altered within the functional connectome in minimal HE (MHE), the earliest stage of HE. Materials and ...

journal_title：Frontiers in neurology

authors： Zhan C,Chen HJ,Gao YQ,Zou TX

更新日期：2019-01-29 00:00:00

abstract：:Over the past decade, it was found that relatively simple sphingolipids, such as ceramide, sphingosine, sphingosine-1-phosphate, and glucosylceramide play important roles in neuronal functions by regulating rates of neuronal growth and differentiation. Homeostasis of membrane sphingolipids in neurons and myelin is ess...

journal_title：Frontiers in neurology

authors： Alessenko AV,Albi E

更新日期：2020-05-21 00:00:00

abstract：INTRODUCTION:We sought to determine whether compliance with scheduled nimodipine in subarachnoid hemorrhage patients impacted patient outcomes, with the intent of guiding future nimodipine management in patients who experience nimodipine-induced hypotension. METHODS:We performed a retrospective analysis of 118 consecu...

journal_title：Frontiers in neurology

authors： Wessell A,Kole MJ,Badjatia N,Parikh G,Albrecht JS,Schreibman DL,Simard JM

更新日期：2017-06-09 00:00:00

abstract：:Background: Regional cerebral oxygen saturation (rScO2) measured by near-infrared spectroscopy (NIRS) can be used to monitor brain oxygenation in extracorporeal membrane oxygenation (ECMO). ECMO patients that develop acute brain injuries (ABIs) are observed to have worse outcomes. We evaluated the association between ...

journal_title：Frontiers in neurology

authors： Khan I,Rehan M,Parikh G,Zammit C,Badjatia N,Herr D,Kon Z,Hogue C,Mazzeffi M

更新日期：2018-11-23 00:00:00

abstract：:Objectives: To report two novel DNA2 gene mutations causing early onset myopathy with cardiac involvement and late onset mitochondriopathy with rhabdomyolysis. Methods: We performed detailed clinical, muscle histopathology and molecular studies including mitochondrial gene NGS analysis in two patients (Patient 1 and 2...

journal_title：Frontiers in neurology

authors： González-Del Angel A,Bisciglia M,Vargas-Cañas S,Fernandez-Valverde F,Kazakova E,Escobar RE,Romero NB,Jardel C,Rucheton B,Stojkovic T,Malfatti E

更新日期：2019-10-04 00:00:00

abstract：:Successful implementation of a randomized clinical trial (RCT) for neuro-vascular emergencies such as cerebral infarction, intracerebral hemorrhage, or subarachnoid hemorrhage is extraordinarily challenging. Besides establishing an accurate, hyper-expedited diagnosis among many mimics in a person with acute neurologic...

journal_title：Frontiers in neurology

authors： Rose DZ,Kasner SE

更新日期：2011-10-17 00:00:00

abstract：:Single time point positron emission tomography (PET) studies of patients with amyotrophic lateral sclerosis and frontotemporal dementia (ALS-FTD), have demonstrated hypometabolism or hypermetabolism in certain brain regions. To determine whether longitudinal (at baseline and 20.4 months later) PET and magnetic resonan...

journal_title：Frontiers in neurology

authors： Rajagopalan V,Pioro EP

更新日期：2019-03-19 00:00:00