PM2.5, Fine Particulate Matter: A Novel Player in the Epithelial-Mesenchymal Transition?

abstract：:Bioenergetic profiling of cancer cells is of great potential because it can bring forward new and effective therapeutic strategies along with early diagnosis. Metabolic Control Analysis (MCA) is a methodology that enables quantification of the flux control exerted by different enzymatic steps in a metabolic network th...

journal_title：Frontiers in physiology

authors： Kaambre T,Chekulayev V,Shevchuk I,Tepp K,Timohhina N,Varikmaa M,Bagur R,Klepinin A,Anmann T,Koit A,Kaldma A,Guzun R,Valvere V,Saks V

更新日期：2013-06-28 00:00:00

abstract：:Gut microbiota has been reported to contribute to reduced diet-induced obesity upon cold exposure. Furthermore, gut microbiome fermentation determines the efficacy of exercise for diabetes prevention and enhances exercise performance. However, there have been no systematic examinations of changes in gut microbiome com...

journal_title：Frontiers in physiology

authors： Meng Y,Chen L,Lin W,Wang H,Xu G,Weng X

更新日期：2020-05-04 00:00:00

abstract：:Background: The severity of wildland fires is increasing due to continually hotter and drier summers. Firefighters are required to make life altering decisions on the fireground, which requires analytical thinking, problem solving, and situational awareness. This study aimed to determine the effects of very hot (45°C;...

journal_title：Frontiers in physiology

authors： Williams-Bell FM,Aisbett B,Murphy BA,Larsen B

更新日期：2017-10-24 00:00:00

abstract：:Sulfur is both crucial to life and a potential threat to health. While colonic sulfur metabolism mediated by eukaryotic cells is relatively well studied, much less is known about sulfur metabolism within gastrointestinal microbes. Sulfated compounds in the colon are either of inorganic (e.g., sulfates, sulfites) or or...

journal_title：Frontiers in physiology

authors： Carbonero F,Benefiel AC,Alizadeh-Ghamsari AH,Gaskins HR

更新日期：2012-11-28 00:00:00

abstract：:A soccer match induce changes in physiological stress biomarkers as testosterone (T), cortisol (C), and testosterone:cortisol (T:C) ration. Hydration state may also modulate these hormones, and therefore may alter the anabolic/catabolic balance in response to soccer match. The role of hydration status before the match...

journal_title：Frontiers in physiology

authors： Castro-Sepulveda M,Ramirez-Campillo R,Abad-Colil F,Monje C,Peñailillo L,Cancino J,Zbinden-Foncea H

更新日期：2018-09-26 00:00:00

abstract：:Directed cell migration is essential all along an individual's life, from embryogenesis to tissue repair and cancer metastasis. Thus, due to its biomedical relevance, directed cell migration is currently under intense research. Directed cell migration has been shown to be driven by an assortment of external biasing cu...

journal_title：Frontiers in physiology

authors： Barriga EH,Theveneau E

更新日期：2020-11-25 00:00:00

abstract：:3-iodothyronamine (T1AM) is an endogenous amine, that has been detected in many rodent tissues, and in human blood. It has been hypothesized to derive from thyroid hormone metabolism, but this hypothesis still requires validation. T1AM is not a ligand for nuclear thyroid hormone receptors, but stimulates with nanomola...

journal_title：Frontiers in physiology

authors： Zucchi R,Accorroni A,Chiellini G

更新日期：2014-10-16 00:00:00

abstract：:Background: Periodontitis is a chronic inflammatory disease with a possible infectious component. Anemia of inflammation (AI) occurring in various chronic diseases alters the hemoglobin (Hb) concentration and iron status. Currently, the association between periodontitis and AI is still controversial. The aim of this s...

journal_title：Frontiers in physiology

authors： Wu D,Lin Z,Zhang S,Cao F,Liang D,Zhou X

更新日期：2020-01-31 00:00:00

abstract：:Survivors of cerebral aneurysm rupture are at risk for significant morbidity and neurological deficits. Much of this is related to the effects of blood in the subarachnoid space which induces an inflammatory cascade with numerous downstream consequences. Recent clinical trials have not been able to reduce the toxic ef...

journal_title：Frontiers in physiology

authors： Blackburn SL,Kumar PT,McBride D,Zeineddine HA,Leclerc J,Choi HA,Dash PK,Grotta J,Aronowski J,Cardenas JC,Doré S

更新日期：2018-05-31 00:00:00

abstract：:Dental and periodontal tissue development is a complex process involving various cell-types. A finely orchestrated network of communications between these cells is implicated. During early development, communications between cells from the oral epithelium and the underlying mesenchyme govern the dental morphogenesis w...

journal_title：Frontiers in physiology

authors： Gama A,Navet B,Vargas JW,Castaneda B,Lézot F

更新日期：2015-11-05 00:00:00

abstract：:Increased central sympathetic drive is a hallmark of several important clinical conditions including essential hypertension, heart failure, chronic kidney disease, and insulin resistance. Afferent signaling from the kidneys has been identified as an important contributor to elevated central sympathetic drive and incre...

journal_title：Frontiers in physiology

authors： Schlaich MP,Hering D,Sobotka P,Krum H,Lambert GW,Lambert E,Esler MD

更新日期：2012-02-02 00:00:00

abstract：:This study aims to investigate the embryo development potential of extending the culture of abnormally fertilized zygotes with no pronuclear (0PN), monopronuclear (1PN), and poor-quality day 3 embryos and to determine the associated clinical outcomes. This is a retrospective study performed between January 2014 and Ma...

journal_title：Frontiers in physiology

authors： Chen X,Shi S,Mao J,Zou L,Yu K

更新日期：2020-11-04 00:00:00

abstract：:In our previous study, we reported a high temperature adapted strain (HTAS) of the predatory mite Neoseiulus barkeri was artificially selected via a long-term heat acclimation (35°C) and frequent heat hardenings. To understand the molecular basis of heat acclimation, 'omics' analyses were performed to compare the diff...

journal_title：Frontiers in physiology

authors： Tian CB,Li YY,Huang J,Chu WQ,Wang ZY,Liu H

更新日期：2020-04-29 00:00:00

abstract：:Genome-wide association studies and physiological investigations have linked alterations in acid-base transporters to hypertension. Accordingly, Na(+)-coupled HCO(-) 3-transporters, Na(+)/H(+)-exchangers, and anion-exchangers have emerged as putative mechanistic components in blood pressure disturbances. Even though h...

journal_title：Frontiers in physiology

authors： Boedtkjer E,Aalkjaer C

更新日期：2013-12-24 00:00:00

abstract：:The human brain is constantly active and even small limitations to cerebral blood flow (CBF) may be critical for preserving oxygen and substrate supply, e.g., during exercise and hypoxia. Exhaustive exercise evokes a competition for the supply of oxygenated blood between the brain and the working muscles, and inabilit...

journal_title：Frontiers in physiology

authors： Kim YS,van der Ster BJP,Brassard P,Secher NH,van Lieshout JJ

更新日期：2021-01-15 00:00:00

abstract：:The effect of Withania somnifera a medicinal plant seed extract was tested against lesser mulberry pyralid, a potential pest of mulberry. The mulberry leaves were used for silk production in rural areas of northern Iran. The extract was administered orally by leaf dipping method in two lower (5%W/V) and higher (15%W/V...

journal_title：Frontiers in physiology

authors： Afraze Z,Sendi JJ,Karimi-Malati A,Zibaee A

更新日期：2020-08-07 00:00:00

abstract：:Although interest in several areas of cephalopod research has emerged over the last decades (e.g., neurobiology, aquaculture, genetics, and welfare), especially following their 2010 inclusion in the EU Directive on the use of animals for experimental purposes, knowledge regarding the parasites of cephalopods is lackin...

journal_title：Frontiers in physiology

authors： Roumbedakis K,Drábková M,Tyml T,di Cristo C

更新日期：2018-11-20 00:00:00

abstract：:Giant clams live in symbiosis with extracellular zooxanthellae and display high rates of growth and shell formation (calcification) in light. Light-enhanced calcification requires an increase in the supply of Ca2+ to, and simultaneously an augmented removal of H+ from, the extrapallial fluid where shell formation occu...

journal_title：Frontiers in physiology

authors： Ip YK,Hiong KC,Goh EJK,Boo MV,Choo CYL,Ching B,Wong WP,Chew SF

更新日期：2017-10-10 00:00:00

abstract：:Odontoblast cells generated from human dental pulp stem/progenitor cells (hDPSCs) secrete reparative dentin in responds to an injury. Endogenous Wnt signaling is also activated during this process, and these Wnt-activated cells are responsible for the following repair response. R-spondin 2 (Rspo2) is a potent stem cel...

journal_title：Frontiers in physiology

authors： Gong Y,Yuan S,Sun J,Wang Y,Liu S,Guo R,Dong W,Li R

更新日期：2020-08-07 00:00:00

abstract：:Fatigue is one of the most debilitating symptoms of multiple sclerosis (MS), and the underlying mechanisms are poorly understood. When exposed to a physical or cognitive challenge, individuals with MS tend to exhibit greater declines in task performance (performance fatigability) and increased levels of self-reported ...

journal_title：Frontiers in physiology

authors： Gould JR,Reineberg AE,Cleland BT,Knoblauch KE,Clinton GK,Banich MT,Corboy JR,Enoka RM

更新日期：2018-10-17 00:00:00

abstract：:Eccentric loading is an effective stimulus for muscle hypertrophy and strength gains, however, the effect of lengthening velocity is under debate. The purpose of the current study was to investigate the influence of muscle lengthening velocity during eccentric training on muscle hypertrophy and strength gains at a giv...

journal_title：Frontiers in physiology

authors： Marzilger R,Bohm S,Mersmann F,Arampatzis A

更新日期：2019-07-31 00:00:00

abstract：:Sex determination/sex differentiation is determined by genetics, environmental factors, or the interactions of the two. The Transformer-2 (Tra-2) gene plays an important role in the sex determination cascade signal pathway in insects. In this study, the Tra-2 gene was isolated and characterized from the cDNA library o...

journal_title：Frontiers in physiology

authors： Cai L,Zheng J,Jia Y,Gu Z,Liu S,Chi M,Cheng S

更新日期：2020-07-09 00:00:00

abstract：:The hippocampus is known as a neuronal structure involved in learning, memory and spatial navigation using multi-sensory cues. However, the basic features of its response to acoustic stimuli without any behavioral tasks (conditioning) remains poorly studied. Here, we investigated the CA3 response to auditory stimuli u...

journal_title：Frontiers in physiology

authors： Wang N,Gan X,Liu Y,Xiao Z

更新日期：2017-11-21 00:00:00

abstract：:The aim of this perspective article is to share with the community of ion channel scientists our thoughts and expectations regarding the increasing role that computational tools will play in the future of our field. The opinions and comments detailed here are the result of a 3-day long international exploratory worksh...

journal_title：Frontiers in physiology

authors： Abriel H,de Lange E,Kucera JP,Loussouarn G,Tarek M

更新日期：2013-12-26 00:00:00

abstract：:Social attachment formed by filial imprinting in newborn chicks undergoes a process of memory consolidation that involves rearrangement of its neural storage substrates. In the first 3 h after imprinting it depends on the integrity of the intermediate medial mesopallium (IMM) and beyond that time on unidentified memor...

journal_title：Frontiers in physiology

authors： Tiunova AA,Komissarova NV,Anokhin KV

更新日期：2019-03-29 00:00:00

abstract：:Molecular chaperones are stress proteins that allow the correct folding or unfolding as well as the assembly or disassembly of macromolecular cellular components. Changes in expression and post-translational modifications of chaperones have been linked to a number of age- and stress-related diseases including cancer, ...

journal_title：Frontiers in physiology

authors： Penna C,Sorge M,Femminò S,Pagliaro P,Brancaccio M

更新日期：2018-03-16 00:00:00

abstract：:The use of intravenous vitamin C (IVC) for cancer therapy has long been an area of intense controversy. Despite this, high dose IVC has been administered for decades by complementary health care practitioners and physicians, with little evidence base resulting in inconsistent clinical practice. In this review we pose ...

journal_title：Frontiers in physiology

authors： Carr AC,Cook J

更新日期：2018-08-23 00:00:00

abstract：:As arteries become stiffer with aging, reflected waves move faster and augment late systolic pressure. Few studies have described the age-related changes in both peripheral and central systolic blood pressures in populations. We investigated the age dependency of peripheral (pSBP) and central (cSBP) systolic pressure ...

journal_title：Frontiers in physiology

authors： Wojciechowska W,Li Y,Stolarz-Skrzypek K,Kawecka-Jaszcz K,Staessen JA,Wang JG,European Project on Genes in Hypertension and the JingNing Study Investigators.

更新日期：2012-06-15 00:00:00

abstract：:Troponin I (TnI) is a major regulator of cardiac muscle contraction and relaxation. During physiological and pathological stress, TnI is differentially phosphorylated at multiple residues through different signaling pathways to match cardiac function to demand. The combination of these TnI phosphorylations can exhibit...

journal_title：Frontiers in physiology

authors： Salhi HE,Hassel NC,Siddiqui JK,Brundage EA,Ziolo MT,Janssen PM,Davis JP,Biesiadecki BJ

更新日期：2016-12-15 00:00:00

abstract：:Introduction: Although short-term (approximately 10-min) fatiguing DP has been reported not to alter the joint kinematics or displacement of the centre of mass (COM) of high-level skiers, we hypothesize that prolonged DP does change these kinematics, since muscular strength is impaired following endurance events lasti...

journal_title：Frontiers in physiology

authors： Zoppirolli C,Bortolan L,Stella F,Boccia G,Holmberg HC,Schena F,Pellegrini B

更新日期：2018-07-25 00:00:00