The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice.

Abstract:

:Silver Nanoparticles (AgNPs), an epitome of nanotechnology, appear in everyday products such as water filters, printer ink, toothpaste, food packaging and cosmetics mostly due to their bactericidal properties. Given this high level of public exposure, the safety of AgNPs has never been fully established. The unsafe use of AgNPs could pose a real threat, not only to public health but also to economic growth in many industries. In this paper, we tested the effect of AgNPs on memory, learning, social behaviour and motor function of BALB/C mice. Outcomes of the present study suggested an impairment of these functions in AgNPs treated groups. Overall, obtained data support the evidence that the systemic exposure to AgNPs may result in alteration of the cerebral cognition and warrants further consideration on the impact of the AgNPs on human health with respect to their potential neurotoxicity.

authors

Greish K,Alqahtani AA,Alotaibi AF,Abdulla AM,Bukelly AT,Alsobyani FM,Alharbi GH,Alkiyumi IS,Aldawish MM,Alshahrani TF,Pittalà V,Taurin S,Kamal A

doi

10.3390/ijerph16010148

subject

Has Abstract

pub_date

2019-01-08 00:00:00

issue

1

eissn

1661-7827

issn

1660-4601

pii

ijerph16010148

journal_volume

16

pub_type

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