Gremlin Regulates Podocyte Apoptosis via Transforming Growth Factor-β (TGF-β) Pathway in Diabetic Nephropathy.

abstract：:BACKGROUND Leptin plays a crucial role in bone metabolism, and its level is related to bone callus formation in the fracture repair process. The objective of this study was to evaluate the effect of recombinant leptin on the healing process of femoral fractures in rats. MATERIAL AND METHODS Forty-eight male Sprague Da...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu P,Cai M

更新日期：2017-01-15 00:00:00

abstract：:Coronary artery disease is the leading cause of death for both men and women in the United States. While its incidence in men has been long appreciated, the impact on women has been underestimated for many years. This is in part because coronary artery disease generally appears later in women, the incidence increasing...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： McLarty A,Mann N,Lawson WE,Foster A

更新日期：2003-06-01 00:00:00

abstract：:BACKGROUND The aim of our study was to investigate the risk factors for falls in the rheumatoid arthritis (RA) patient population in Poland. This would be a major step towards the development of new fall prevention programs. MATERIAL AND METHODS There were 450 RA patients who met the criteria of the American College o...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Mikos M,Kucharska E,Lulek AM,Kłosiński M,Batko B

更新日期：2020-04-15 00:00:00

abstract：:BACKGROUND The relationship between clopidogrel-resistance (CR) and polymorphism located in genes encoding clopidogrel metabolism-related enzymes has not been fully explored. Thus far, few studies on CR-associated polymorphism have been conducted in the Chinese population. The purpose of this study was to identify CYP...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Su Q,Li J,Tang Z,Yang S,Xing G,Liu T,Peng H

更新日期：2019-09-23 00:00:00

abstract：BACKGROUND:The aim of this meta-analysis was to compare the outcomes of proximal femoral nail (PFN) and dynamic hip screw (DHS) in treatment of intertrochanteric fractures. MATERIAL AND METHODS:Relevant randomized or quasi-randomized controlled studies comparing the effects of PFN and DHS were searched for following t...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang K,Zhang S,Yang J,Dong W,Wang S,Cheng Y,Al-Qwbani M,Wang Q,Yu B

更新日期：2014-09-12 00:00:00

abstract：:HIV (human immunodeficiency virus) infection may produce no clinical symptoms for 10 years on average. However, after many years of infection most people develop symptoms that indicate progression of the disease. There are no regular characteristic symptoms or early stage, and no logical sequence of AIDS indicator dis...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Rzewnicki I,Olszewska E,Rogowska-Szadkowska D

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Growing resistance to antibiotics among both community-acquired and hospital pathogens is making the treatment of most infections increasingly difficult. Therefore, the aim of our multi-center study was to determine the antimicrobial susceptibility of the most frequent aerobic microorganisms isolated from ch...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Dzierzanowska-Fangrat K,Semczuk K,Łopaciuk U,Kurlenda J,Małafiej E,Puacz E,Stalmaska-Dworak E,Dzierzanowska D

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:This study presents a systematic analysis of atherothrombotic lesions taken by percutaneous atherectomy and post mortem examination from coronary arteries, in order to identify: a) the topographic occurrence of fibrinogen and smooth muscle cells (SMCs), b) their independent expression in stable and unstable ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Loukas M,Dabrowski M,Wagner T,Walczak E,Witkowski A,Ruzyłło W

更新日期：2002-04-01 00:00:00

abstract：:BACKGROUND This study aimed to identify hub genes and pathways in a rat model of renal ischemia-reperfusion injury (IRI) using bioinformatics analysis of the Gene Expression Omnibus (GEO) microarray dataset and integration of gene expression profiles. MATERIAL AND METHODS GEO software and the GEO2R calculation method ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Guo A,Wang W,Shi H,Wang J,Liu T

更新日期：2019-11-08 00:00:00

abstract：:Ectopic pregnancy is a rare phenomenon in mammals. The most common localization is an oviduct, ovary and abdominal cavity. Confirmation of the ectopic pregnancy is always a difficult medical problem. The diagnosis is mainly based on the patient's history and gynecological examination. This paper concerns a case report...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Cyganek A,Marianowski L

更新日期：2000-07-01 00:00:00

abstract：:BACKGROUND The purpose of this study was to investigate the effects of sevoflurane on cancer immunosurveillance and metastasis in non-small-cell lung cancer (NSCLC). MATERIAL AND METHODS NCI-H23 cells, a human NSCLC cell line, were incubated with or without sevoflurane at the concentrations of 0, 12.5, 25, 50, 100, an...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jeon S,Kim HK,Kwon JY,Baek SH,Ri HS,Choi HJ,Cho HR,Lee YS,Kim JY,Kim J,Bae J,Lee HJ

更新日期：2020-11-03 00:00:00

abstract：BACKGROUND:Some studies have evaluated the association between the Ubiquilin 1 (UBQLN1) gene UBQ-8i polymorphism and Alzheimer's disease (AD). However, the results remain uncertain. We carried out a meta-analysis to derive a more comprehensive estimation of this association. MATERIAL/METHODS:Case-control studies were ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang T,Jia Y

更新日期：2014-11-12 00:00:00

abstract：:BACKGROUND The purpose of this study was to evaluate the effects of prosthetic material and framework design on the stress within dental implants and peripheral bone using finite element analysis (FEA). MATERIAL AND METHODS A mandibular implant-supported fixed dental prosthesis with different prosthetic materials [cob...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Arinc H

更新日期：2018-06-22 00:00:00

abstract：:BACKGROUND Aging is characterized by progressive deterioration in metabolic and physiological process. The present research assessed the antagonistic effects and mechanisms of Ginsenoside Rg1 (Rg1) on aging of HSCs/HPCs. MATERIAL AND METHODS Fifty male Sprague-Dawley (SD) rats were treated and divided into the followi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhou Y,Wang YP,He YH,Ding JC

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate visual performance, contrast sensitivity, and patient satisfaction in patients undergoing cataract surgery with bilateral implantation of the Tecnis ZMB00 diffractive multifocal IOL (intraocular lens). MATERIAL/METHODS:This was a prospective study of 40 eyes of 20 patie...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lubiński W,Gronkowska-Serafin J,Podborączyńska-Jodko K

更新日期：2014-07-15 00:00:00

abstract：BACKGROUND:This study aimed to determine the efficacy and safety of recombinant Mycobacterium tuberculosis ESAT-6 protein for diagnosis of pulmonary tuberculosis (TB). MATERIAL AND METHODS:A phase II trial was performed in 158 patients with pulmonary TB (145 initially-treated and 13 re-treated) and 133 healthy subject...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Sun QF,Xu M,Wu JG,Chen BW,Du WX,Ding JG,Shen XB,Su C,Wen JS,Wang GZ

更新日期：2013-11-12 00:00:00

abstract：BACKGROUND:Bax activation and intracellular redistribution as well as its prognostic significance during steroid-induced apoptosis of leukemic cells in childhood acute lymphoblastic leukemia (ALL) remain a matter of controversy. The purpose of this study was to assess time-resolved changes in Bax activation and its int...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Urasiński T,Urasińska E,Grabarek J,Fydryk J,Domagała W

更新日期：2009-06-01 00:00:00

abstract：:BACKGROUND Results of the landmark Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) trial comparing rhythm control and rate control strategies has led to dramatic changes in the pharmacological management of non-valvular atrial fibrillation (NVAF) patients. We sought to investigate the effect ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Hou XX,Du X,Zheng D,Li YM,He L,Li XX,Dong JZ

更新日期：2019-06-30 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate potential morphological alterations of gray and white matter in patients with optic neuritis (ON) and their relationship with behavioral performance, using voxel-based morphometry (VBM). MATERIAL/METHODS:Twelve (4 males, 8 females) patients with ON and 12 (4 males, 8...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huang X,Zhang Q,Hu PH,Zhong YL,Zhang Y,Wei R,Xu TT,Shao Y,Oculopathy fMRI study group.

更新日期：2016-04-05 00:00:00

abstract：:The purpose of this study was to investigate the distribution of Chlamydia trachomatis (CT) genotypes in infective diseases of the female lower genital tract, especially in cervical diseases. This study included 128 CT-positive women. DNA was extracted from cervical swabs. Omp1 gene PCR-RFLP and sequencing were used t...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen Y,Chen J,Yang L,Jiang Y,Li L,Yi W,Lan L,Zhang L

更新日期：2017-09-17 00:00:00

abstract：:BACKGROUND This study investigated the effect of occupational stress and circadian clock gene polymorphism on sleep disorder of oil workers in Xinjiang, China. MATERIAL AND METHODS We enrolled 2300 Xinjiang oil workers who had been working for at least 1 year. The Chinese revised version of the Occupational Stress Que...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ning L,Shi L,Tao N,Li R,Jiang T,Liu J

更新日期：2020-08-01 00:00:00

abstract：:The main controversies surrounding the management of DCIS evolve around the need for adjuvant radiotherapy (RT) after adequate local excision (LE) of localized lesions and the role of adjuvant endocrine therapy. All randomized controlled trials (RCTs) examining the role of adjuvant RT and tamoxifen after LE were revie...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Mokbel K

更新日期：2005-03-01 00:00:00

abstract：:BACKGROUND This study aimed to establish an easy, safe, and cost-saving intestinal anastomotic method. MATERIAL AND METHODS Between January 2014 and February 2016, a total of 150 patients with gastric cancer who underwent surgery in the Department of General Surgery of Xuzhou Medical University Affiliated Hospital wer...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yao L,Li C,Zhu X,Shao Y,Meng S,Shi L,Wang H

更新日期：2016-11-26 00:00:00

abstract：:BACKGROUND Endothelial progenitor cells (EPCs) were found to be a potential therapeutic choice for low extremity deep vein thrombosis. The aim of our research was to investigate the effect of resveratrol (RSV) on EPCs that may promote thrombus resolution and its potential pathway. MATERIAL AND METHODS EPCs were pretre...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang Y,Du X,Li W,Sang H,Qian A,Sun L,Li X,Li C

更新日期：2018-02-15 00:00:00

abstract：:BACKGROUND Reports show that ultrasound-targeted microbubble destruction (UTMD) is a promising method of gene therapy, and metadherin (MTDH) is related to the development of breast cancer. Thus, we investigated the role of MTDH in breast cancer and compared the effect of suppressing MTDH by shRNA using liposome, UTMD,...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xu J,Wang Y,Li Z,Wang Q,Zhou X,Wu W

更新日期：2019-04-10 00:00:00

abstract：BACKGROUND:After left ventricular assist device (LVAD) implantation, post-operative renal failure is a fairly high risk. While comparing the differences in indicators of renal function associated with the use of three different types of LVAD, this retrospective study was designed to evaluate predictors and outcomes of ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ma L,Fujino Y,Matsumiya G,Sawa Y,Mashimo T

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Vibrio vulnificus (V. vulnificus) is a seafood-borne infectious pathogen that can be lethal to humans. The infection has been correlated with pre-existing liver disease, particularly liver cirrhosis. Awareness of V. vulnificus infection among Japanese citizens is low, despite the increasing number of patient...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Nagao Y,Matsuoka H,Seike M,Yamasaki K,Kato J,Nakajima T,Miyazaki Y,Ohno T,Inuzuka S,Ohira H,Yokosuka O,Yatsuhashi H,Mori T,Honda K,Kawaguchi T,Ide T,Sata M

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Freezing of Gait (FOG) can be a serious problem in Parkinson's disease (PD) and is usually refractory to medical treatment. Botulinum toxin (BTX) type A has been reported to relieve FOG in small open label studies. MATERIAL/METHODS:We performed a double-blind, placebo-controlled, parallel-group study using ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Fernandez HH,Lannon MC,Trieschmann ME,Friedman JH

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the feasibility of co-registering preoperative MRI and postoperative CT and to assess the position of the electrode within the cochlea. MATERIAL/METHODS:In a series of 14 patients, high-resolution MRI datasets of the cochlea obtained before implantation and multirow CT ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Neri E,Berrettini S,Salvatori L,Forli F,Franceschini SS,Bartolozzi C

更新日期：2005-10-01 00:00:00

abstract：:The accurate and high-throughput detection of drug resistance-related multiple point mutations remains a challenge. Although the combination of molecular beacons with bio-immobilization technology, such as microarray, is promising, its application is difficult due to the ineffective immobilization of molecular beacons...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen Q,Wu N,Xie M,Zhang B,Chen M,Li J,Zhuo L,Kuang H,Fu W

更新日期：2012-04-01 00:00:00