Delay discounting without decision-making: medial prefrontal cortex and amygdala activations reflect immediacy processing and correlate with impulsivity and anxious-depressive traits.

abstract：:It is suggested that striatal cAMP responsive element binding protein (CREB) regulates sensitivity to psychostimulants. To test the cell-specificity of this hypothesis we examined the effects of a dominant-negative CREB protein variant expressed in dopamine receptor D1 (D1R) neurons on cocaine-induced behaviors. A tra...

journal_title：Frontiers in behavioral neuroscience

authors： Bilbao A,Rieker C,Cannella N,Parlato R,Golda S,Piechota M,Korostynski M,Engblom D,Przewlocki R,Schütz G,Spanagel R,Parkitna JR

更新日期：2014-06-11 00:00:00

abstract：:Cross-situational word learning is based on the notion that a learner can determine the referent of a word by finding something in common across many observed uses of that word. Here we propose an adaptive learning algorithm that contains a parameter that controls the strength of the reinforcement applied to associati...

journal_title：Frontiers in behavioral neuroscience

authors： Tilles PF,Fontanari JF

更新日期：2013-11-19 00:00:00

abstract：:We examined the ability of observers to detect the 3D curvature of motion paths when binocular disparity and motion information were present. On each trial, two displays were observed through shutter-glasses. In one display, a sphere moved along a linear path in the horizontal and depth dimensions. In the other displa...

journal_title：Frontiers in behavioral neuroscience

authors： Pierce RS,Bian Z,Braunstein ML,Andersen GJ

更新日期：2013-02-20 00:00:00

abstract：:"Social facilitation" refers to the enhancement or impairment of performance engendered by the mere presence of others. It has been demonstrated for a diversity of behaviors. This study assessed whether it also concerns attention and eye movements and if yes, which decision-making mechanisms it affects. Human voluntee...

journal_title：Frontiers in behavioral neuroscience

authors： Tricoche L,Ferrand-Verdejo J,Pélisson D,Meunier M

更新日期：2020-01-08 00:00:00

abstract：:Animals rely on sensory feedback from their environment to guide locomotion. For instance, visually guided animals use patterns of optic flow to control their velocity and to estimate their distance to objects (e.g., Srinivasan et al., 1991, 1996). In this study, we investigated how acoustic information guides locomot...

journal_title：Frontiers in behavioral neuroscience

authors： Warnecke M,Lee WJ,Krishnan A,Moss CF

更新日期：2016-04-25 00:00:00

abstract：:Implementation intention has proven effective in regulating intense emotions but is found to be difficult when instructed regulation is used. Here, we aim to test whether automatic reappraisal-based implementation intention (RII) downregulates intense negative emotion more efficiently than controlled reappraisal (CR) ...

journal_title：Frontiers in behavioral neuroscience

authors： Chen S,Yu K,Yang J,Yuan J

更新日期：2020-07-14 00:00:00

abstract：:Early-life stress (ELS) poses risks for developmental and mental health problems throughout the lifespan. More research is needed regarding how specific ELS experiences influence specific aspects of neurodevelopment. We examined the association between ELS, defined as severe adversity (e.g., domestic violence, caregiv...

journal_title：Frontiers in behavioral neuroscience

authors： Hambrick EP,Brawner TW,Perry BD

更新日期：2019-08-06 00:00:00

abstract：:Major depression (MD) is one of the most common psychiatric disorders, severely affecting the quality of life of millions of people worldwide. Despite the availability of several classes of antidepressants, treatment efficacy is still very variable and many patients do not respond to the treatment. Clomipramine (CMI),...

journal_title：Frontiers in behavioral neuroscience

authors： Balsevich G,Namendorf C,Gerlach T,Uhr M,Schmidt MV

更新日期：2015-01-06 00:00:00

abstract：:Dysregulations in the brain serotonergic system and exposure to environmental stressors have been implicated in the development of major depressive disorder. Here, we investigate the interactions between the stress and serotonergic systems by characterizing the behavioral and biochemical effects of chronic stress appl...

journal_title：Frontiers in behavioral neuroscience

authors： Wong P,Sze Y,Gray LJ,Chang CC,Cai S,Zhang X

更新日期：2015-04-27 00:00:00

abstract：:Physical inactivity has emerged as an important and risk factor for cardiovascular and metabolic diseases, independent of levels of exercise engagement. Moreover, inactivity is associated with poor brain functioning. However, little data on the effects of physical inactivity on the brain is available and few methods a...

journal_title：Frontiers in behavioral neuroscience

authors： Roemers P,Hulst Y,van Heijningen S,van Dijk G,van Heuvelen MJG,De Deyn PP,van der Zee EA

更新日期：2019-10-04 00:00:00

abstract：:Recent studies have used conditional knockout mice to selectively delete the D2 autoreceptor; however, these approaches result in global deletion of D2 autoreceptors early in development. The present study takes a different approach using RNA interference (RNAi) to knockdown the expression of the D2 receptors (D2R) in...

journal_title：Frontiers in behavioral neuroscience

authors： Budygin EA,Oleson EB,Lee YB,Blume LC,Bruno MJ,Howlett AC,Thompson AC,Bass CE

更新日期：2017-01-19 00:00:00

abstract：:Reduction of mu activity within the EEG is an indicator of cognitive empathy and can be generated in response to visual depictions of others in pain. The current study tested whether this brain response can be modulated by an auditory and a chemosensory context. Participants observed pictures of painful and non-painfu...

journal_title：Frontiers in behavioral neuroscience

authors： Hoenen M,Lübke KT,Pause BM

更新日期：2018-10-16 00:00:00

abstract：:Selective serotonin reuptake inhibitors (SSRIs) are used extensively in the treatment of depression and anxiety disorders. The therapeutic benefits of SSRIs typically require several weeks of continuous treatment. Intriguingly, according to clinical reports, symptoms of anxiety may actually increase during the early s...

journal_title：Frontiers in behavioral neuroscience

authors： Ravinder S,Pillai AG,Chattarji S

更新日期：2011-12-28 00:00:00

abstract：:Discrete populations of brain cells signal differing types of spatial information. These "spatial cells" are largely confined to a closely-connected network of sites. We describe here, for the first time, cells in the anterior claustrum of the freely-moving rat encoding place, boundary and object information. This nov...

journal_title：Frontiers in behavioral neuroscience

authors： Jankowski MM,O'Mara SM

更新日期：2015-10-14 00:00:00

abstract：:Emotion regulation therapy (ERT) is an efficacious treatment for distress disorders (i.e., depression and anxiety), predicated on a conceptual model wherein difficult to treat distress arises from intense emotionality (e.g., neuroticism, dispositional negativity) and is prolonged by negative self-referentiality (e.g.,...

journal_title：Frontiers in behavioral neuroscience

authors： Scult MA,Fresco DM,Gunning FM,Liston C,Seeley SH,García E,Mennin DS

更新日期：2019-02-04 00:00:00

abstract：:First-line treatment of major depression includes administration of a selective serotonin reuptake inhibitor (SSRI), yet studies suggest that remission rates following two trials of an SSRI are <50%. The authors examine the putative biological substrates underlying "treatment resistant depression (TRD)" with the goal ...

journal_title：Frontiers in behavioral neuroscience

authors： Coplan JD,Gopinath S,Abdallah CG,Berry BR

更新日期：2014-05-20 00:00:00

abstract：INTRODUCTION:Conflicting data exist on sensitivity changes of the melanocortin system during diet-induced obesity. We hypothesized that melanocortin sensitivity depends on diet composition, in particular on the fat content rather than the level of obesity. The aim of this study was to determine the influence of diet co...

journal_title：Frontiers in behavioral neuroscience

authors： van den Heuvel JK,Eggels L,van Rozen AJ,Fliers E,Kalsbeek A,Adan RA,la Fleur SE

更新日期：2015-12-24 00:00:00

abstract：:Dysregulation of the hypothalamic-pituitary-adrenal (HPA) stress response has been suggested to play a role in vulnerability to stress-related disorders, such as depression. Prenatal alcohol exposure (PAE) may result in HPA dysregulation, which in turn may predispose individuals to the effects of stress exposure throu...

journal_title：Frontiers in behavioral neuroscience

authors： Lam VYY,Raineki C,Takeuchi LE,Ellis L,Woodward TS,Weinberg J

更新日期：2018-03-09 00:00:00

abstract：:Darwin (1872) postulated that emotional expressions contain universals that are retained across species. We recently showed that human rating responses were strongly affected by a listener's familiarity with vocalization types, whereas evidence for universal cross-taxa emotion recognition was limited. To disentangle t...

journal_title：Frontiers in behavioral neuroscience

authors： Scheumann M,Hasting AS,Zimmermann E,Kotz SA

更新日期：2017-10-24 00:00:00

abstract：:Testosterone reduces anxiety-like behaviors in rodents and increases exploration of anxiogenic parts of the environment. Effects of testosterone on innate defensive behaviors remain understudied. Here, we demonstrate that exogenous testosterone reduces aversion to cat odor in male mice. This is reflected as increased ...

journal_title：Frontiers in behavioral neuroscience

authors： Tong WH,Abdulai-Saiku S,Vyas A

更新日期：2019-02-26 00:00:00

abstract：:Chemotaxis is a powerful paradigm to study how orientation behavior is driven by sensory stimulation. Drosophila larvae navigate odor gradients by controlling the duration of their runs and the direction of their turns. Straight runs and wide-amplitude turns represent two extremes of a behavioral continuum. Here we es...

journal_title：Frontiers in behavioral neuroscience

authors： Gomez-Marin A,Louis M

更新日期：2014-02-13 00:00:00

abstract：:The article is a perspective on utilization of microorganisms and chemosignals in studying human economic behavior. Research in biological roots of economic development has already confirmed that parasitic pressure influenced the creation and development of cultural norms and institutions. However, other effects of mi...

journal_title：Frontiers in behavioral neuroscience

authors： Houdek P

更新日期：2018-05-01 00:00:00

abstract：:Medical decisions will often entail a broad search for relevant information. No sources alone may offer a complete picture, and many may be selective in their presentation. This selectivity may induce forgetting for previously learned material, thereby adversely affecting medical decision-making. In the study phase of...

journal_title：Frontiers in behavioral neuroscience

authors： Coman D,Coman A,Hirst W

更新日期：2013-06-14 00:00:00

abstract：:Psychiatric disorders are multifactorial diseases with etiology that may involve genetic factors, early life environment and stressful life events. The neurodevelopmental hypothesis of schizophrenia is based on a wealth of data on increased vulnerability in individuals exposed to insults during the perinatal period. M...

journal_title：Frontiers in behavioral neuroscience

authors： Girardi CE,Zanta NC,Suchecki D

更新日期：2014-09-10 00:00:00

abstract：:The locus coeruleus (LC) is the sole source of noradrenergic projections to the cortex and essential for attention-dependent cognitive processes. In this study we used unilateral optogenetic silencing of the LC in an attentional set-shifting task (ASST) to evaluate the influence of the LC on prefrontal cortex-dependen...

journal_title：Frontiers in behavioral neuroscience

authors： Janitzky K,Lippert MT,Engelhorn A,Tegtmeier J,Goldschmidt J,Heinze HJ,Ohl FW

更新日期：2015-11-04 00:00:00

abstract：:Increased reactivity to stress is maladaptive and linked to abnormal behaviors and psychopathology. Chronic unpredictable stress (CUS) alters catecholaminergic neurotransmission and remodels neuronal circuits involved in learning, attention and decision making. Glial-derived neurotrophic factor (GDNF) is essential for...

journal_title：Frontiers in behavioral neuroscience

authors： Buhusi M,Brown CK,Buhusi CV

更新日期：2017-10-10 00:00:00

abstract：PURPOSE:The present study assessed the influence of L-DOPA administration on neostriatal dopamine (DA) transporter (DAT) binding in relation to motor and exploratory behaviors in the rat. METHODS:Rats received injections of 5 mg/kg L-DOPA, 10 mg/kg L-DOPA or vehicle. Motor and exploratory behaviors were assessed for 3...

journal_title：Frontiers in behavioral neuroscience

authors： Nikolaus S,Beu M,De Souza Silva AM,Huston JP,Hautzel H,Chao OY,Antke C,Müller HW

更新日期：2014-12-17 00:00:00

abstract：:5-aza-2'-deoxycytidine (5-aza), an inhibitor of DNA methyltransferases (DNMTs), has been implicated in aversive memory and the function of brain region involved in processing emotion. However, little is known about the role of 5-aza in the reconsolidation of opiate withdrawal memory. In the present study, using the mo...

journal_title：Frontiers in behavioral neuroscience

authors： Liu P,Zhang J,Li M,Sui N

更新日期：2016-03-15 00:00:00

abstract：:Very preterm (VPT) infants need long-lasting hospitalization in the Neonatal Intensive Care Unit (NICU) during which they are daily exposed to pain-related stress. Alterations of DNA methylation at the promoter region of the SLC6A4 have been associated with early adverse experiences in infants. The main aim of the pre...

journal_title：Frontiers in behavioral neuroscience

authors： Provenzi L,Fumagalli M,Sirgiovanni I,Giorda R,Pozzoli U,Morandi F,Beri S,Menozzi G,Mosca F,Borgatti R,Montirosso R

更新日期：2015-04-21 00:00:00

abstract：:Numerous reports indicate that learning and memory of conditioned responses are accompanied by genesis of dendritic spines in the hippocampus, although there is a conspicuous lack of information regarding spine modifications after behavioral extinction. There is ample evidence that treatments that typically produce am...

journal_title：Frontiers in behavioral neuroscience

authors： Garín-Aguilar ME,Díaz-Cintra S,Quirarte GL,Aguilar-Vázquez A,Medina AC,Prado-Alcalá RA

更新日期：2012-03-16 00:00:00