Acute Depletion of D2 Receptors from the Rat Substantia Nigra Alters Dopamine Kinetics in the Dorsal Striatum and Drug Responsivity.

abstract：:Transient global amnesia (TGA) is a disorder characterized by a sudden attack of severe anterograde memory disturbance that is frequently preceded by emotional or physical stress and resolves within 24 h. By using MRI following the acute episode in TGA patients, small lesions in the hippocampus have been observed. Hen...

journal_title：Frontiers in behavioral neuroscience

authors： Griebe M,Nees F,Gerber B,Ebert A,Flor H,Wolf OT,Gass A,Hennerici MG,Szabo K

更新日期：2015-03-09 00:00:00

abstract：:First-line treatment of major depression includes administration of a selective serotonin reuptake inhibitor (SSRI), yet studies suggest that remission rates following two trials of an SSRI are <50%. The authors examine the putative biological substrates underlying "treatment resistant depression (TRD)" with the goal ...

journal_title：Frontiers in behavioral neuroscience

authors： Coplan JD,Gopinath S,Abdallah CG,Berry BR

更新日期：2014-05-20 00:00:00

abstract：:The orbitofrontal cortex (OFC) is a key brain region for decision-making, action control and impulsivity. Quite notably, previous research has identified a double dissociation regarding the role of this cortical territory in impulsive choice. While medial orbitofrontal lesions increase preference for a large but delay...

journal_title：Frontiers in behavioral neuroscience

authors： Ucha M,Roura-Martínez D,Contreras A,Pinto-Rivero S,Orihuel J,Ambrosio E,Higuera-Matas A

更新日期：2019-02-20 00:00:00

abstract：:The presence of an affiliative conspecific may alleviate an individual's stress response in threatening conditions. However, the mechanisms and neural circuitry underlying the process of social buffering have not yet been elucidated. Using the domestic pig as an animal model, we examined the effect of a 4-h maternal a...

journal_title：Frontiers in behavioral neuroscience

authors： Kanitz E,Hameister T,Tuchscherer A,Tuchscherer M,Puppe B

更新日期：2016-11-29 00:00:00

abstract：:Salsolinol, a tetrahydroisoquinoline present in the human and rat brains, is the condensation product of dopamine and acetaldehyde, the first metabolite of ethanol. Previous evidence obtained in vivo links salsolinol with the mesolimbic dopaminergic (DA) system: salsolinol is self-administered into the posterior of th...

journal_title：Frontiers in behavioral neuroscience

authors： Xie G,Krnjević K,Ye JH

更新日期：2013-05-24 00:00:00

abstract：:Alcohol is a widely used and abused substance with numerous negative consequences for human health and safety. Historically, alcohol's widespread, non-specific neurobiological effects have made it a challenge to study in humans. Therefore, model organisms are a critical tool for unraveling the mechanisms of alcohol ac...

journal_title：Frontiers in behavioral neuroscience

authors： Chvilicek MM,Titos I,Rothenfluh A

更新日期：2020-12-15 00:00:00

abstract：:Dopamine mediates diverse functions such as motivation, reward, attention, learning/memory and sleep/arousal. Recent studies using model organisms including the fruit fly, have elucidated various physiological functions of dopamine, and identified specific neural circuits for these functions. Flies with mutations in t...

journal_title：Frontiers in behavioral neuroscience

authors： Ueno T,Kume K

更新日期：2014-09-03 00:00:00

abstract：:Emotional events gain special priority in how they are remembered, with emotionally arousing events typically recalled more vividly and with greater confidence than non-emotional events. In dementia, memory and emotion processing are affected to varying degrees, however, whether emotional enhancement of memory for com...

journal_title：Frontiers in behavioral neuroscience

authors： Kumfor F,Irish M,Hodges JR,Piguet O

更新日期：2014-06-24 00:00:00

abstract：:Differences in selection pressure in nature and labs have profound effects on zebrafish strains. The widely used AB strain of zebrafish has been domesticated over several decades. Recently, there has been an upsurge in the availability of genetically modified lines, e.g., the spiegeldanio (spd), which has a mutation i...

journal_title：Frontiers in behavioral neuroscience

authors： Mustafa A,Roman E,Winberg S

更新日期：2019-11-19 00:00:00

abstract：:The primary aim of this study was to evaluate and compare the effectiveness of two specific Non-Invasive Brain Stimulation (NIBS) paradigms, the repetitive Transcranial Magnetic Stimulation (rTMS), and transcranial Direct Current Stimulation (tDCS), in the upper limb rehabilitation of patients with stroke. Short and l...

journal_title：Frontiers in behavioral neuroscience

authors： D'Agata F,Peila E,Cicerale A,Caglio MM,Caroppo P,Vighetti S,Piedimonte A,Minuto A,Campagnoli M,Salatino A,Molo MT,Mortara P,Pinessi L,Massazza G

更新日期：2016-06-24 00:00:00

abstract：:We examined the ability of observers to detect the 3D curvature of motion paths when binocular disparity and motion information were present. On each trial, two displays were observed through shutter-glasses. In one display, a sphere moved along a linear path in the horizontal and depth dimensions. In the other displa...

journal_title：Frontiers in behavioral neuroscience

authors： Pierce RS,Bian Z,Braunstein ML,Andersen GJ

更新日期：2013-02-20 00:00:00

abstract：:Evidence regarding the association between early drinking (ED) and later dependence is controversial. It has been alternately hypothesized that ED either plays a causal role in the development of dependence or that it is an early marker of increased psychosocial vulnerabilities. Despite a clear rationale for delaying ...

journal_title：Frontiers in behavioral neuroscience

authors： Conde K,Peltzer RI,Gimenez PV,Cremonte M

更新日期：2020-03-05 00:00:00

abstract：:The dopaminergic system is known to be involved in working memory processed by several brain regions like prefrontal cortex (PFC), hippocampus, striatum. In an earlier study we could show that Levodopa but not Modafinil enhanced working memory in a T-maze only during the early phase of training (day 3), whereas the la...

journal_title：Frontiers in behavioral neuroscience

authors： Bezu M,Maliković J,Kristofova M,Engidawork E,Höger H,Lubec G,Korz V

更新日期：2017-10-13 00:00:00

abstract：:When stepping onto a stopped escalator, we often perceive an "odd sensation" that is never felt when stepping onto stairs. The sight of an escalator provides a strong contextual cue that, in expectation of the backward acceleration when stepping on, triggers an anticipatory forward postural adjustment driven by a habi...

journal_title：Frontiers in behavioral neuroscience

authors： Gomi H,Sakurada T,Fukui T

更新日期：2014-03-20 00:00:00

abstract：INTRODUCTION:Conflicting data exist on sensitivity changes of the melanocortin system during diet-induced obesity. We hypothesized that melanocortin sensitivity depends on diet composition, in particular on the fat content rather than the level of obesity. The aim of this study was to determine the influence of diet co...

journal_title：Frontiers in behavioral neuroscience

authors： van den Heuvel JK,Eggels L,van Rozen AJ,Fliers E,Kalsbeek A,Adan RA,la Fleur SE

更新日期：2015-12-24 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fnbeh.2018.00165.]. ...

journal_title：Frontiers in behavioral neuroscience

authors： Spindler M,Koch K,Borisov E,Özyurt J,Sörös P,Thiel C,Bantel C

更新日期：2019-02-19 00:00:00

abstract：:The ability to maintain appropriate gaps to objects in one's environment is important when navigating through a three-dimensional world. Previous research has shown that the visual angle subtended by a lead/approaching object and its rate of change are important variables for timing interceptions, collision avoidance,...

journal_title：Frontiers in behavioral neuroscience

authors： Hosking SG,Davey CE,Kaiser MK

更新日期：2013-05-21 00:00:00

abstract：:When making decisions, people are typically differently sensitive to gains and losses according to the motivational context in which the choice is performed. As hypothesized by Regulatory Focus Theory (RFT), indeed, goals are supposed to change in relation to the set of possible outcomes. In particular, in a promotion...

journal_title：Frontiers in behavioral neuroscience

authors： Lo Gerfo E,Pisoni A,Ottone S,Ponzano F,Zarri L,Vergallito A,Varoli E,Fedeli D,Romero Lauro LJ

更新日期：2018-04-24 00:00:00

abstract：:Stimuli of the environment, like objects, systematically activate the actions they are associated to. These activations occur extremely fast. Nevertheless, behavioral data reveal that, in most cases, these activations are then automatically inhibited, around 100 ms after the occurrence of the stimulus. We thus tested ...

journal_title：Frontiers in behavioral neuroscience

authors： Debruille JB,Touzel M,Segal J,Snidal C,Renoult L

更新日期：2019-05-08 00:00:00

abstract：:The extant literature supports the role of stress in enhancing the susceptibility of drug abuse progressing to a substance use disorder diagnosis. However, the molecular mediators by which stress enhances the progression from cocaine abuse to cocaine use disorder via the mesolimbic pathway remain elusive. In this mini...

journal_title：Frontiers in behavioral neuroscience

authors： Mukhara D,Banks ML,Neigh GN

更新日期：2018-12-21 00:00:00

abstract：Background:Brain investigations identified salience network (SN) comprising the dorsal Anterior Cingulate Cortex (dACC) and the Anterior Insula (AI). Magnetic resonance spectroscopy (MRS) studies revealed the link between the glutamate concentration in the ACC and alterations in attentional scope. Hence, we investigate...

journal_title：Frontiers in behavioral neuroscience

authors： von Düring F,Ristow I,Li M,Denzel D,Colic L,Demenescu LR,Li S,Borchardt V,Liebe T,Vogel M,Walter M

更新日期：2019-10-02 00:00:00

abstract：:Although it has been known for decades that the drug nicotine can improve cognitive function, the nature of its effects and the underlying mechanisms are not well understood. Nicotine activates nicotinic acetylcholine (ACh) receptors (nAChRs) that normally are activated by endogenous ACh, presumably "hijacking" the ch...

journal_title：Frontiers in behavioral neuroscience

authors： Metherate R,Intskirveli I,Kawai HD

更新日期：2012-07-19 00:00:00

abstract：:In animals, emotional memory is classically assessed through pavlovian fear conditioning in which a neutral novel stimulus (conditioned stimulus) is paired with an aversive unconditioned stimulus. After conditioning, the conditioned stimulus elicits a fear response characterized by a wide range of behavioral and physi...

journal_title：Frontiers in behavioral neuroscience

authors： Hegoburu C,Shionoya K,Garcia S,Messaoudi B,Thévenet M,Mouly AM

更新日期：2011-05-19 00:00:00

abstract：THIS STUDY HAD THE FOLLOWING TWO AIMS:First, to explore the effects of acute resistance exercise (RE, i.e., using exercise machines to contract and stretch muscles) on behavioral and electrophysiological performance when performing a cognitive task involving executive functioning in young male adults; Second, to invest...

journal_title：Frontiers in behavioral neuroscience

authors： Tsai CL,Wang CH,Pan CY,Chen FC,Huang TH,Chou FY

更新日期：2014-08-01 00:00:00

abstract：:Exposure to community violence through witnessing or being directly victimized has been associated with conduct problems in a range of studies. However, the relationship between community violence exposure (CVE) and conduct problems has never been studied separately in healthy individuals and individuals with conduct ...

journal_title：Frontiers in behavioral neuroscience

authors： Kersten L,Vriends N,Steppan M,Raschle NM,Praetzlich M,Oldenhof H,Vermeiren R,Jansen L,Ackermann K,Bernhard A,Martinelli A,Gonzalez-Madruga K,Puzzo I,Wells A,Rogers JC,Clanton R,Baker RH,Grisley L,Baumann S,Gundlach

更新日期：2017-11-06 00:00:00

abstract：:Comparisons of cognitive impairments between schizophrenia (SZ) and bipolar disorder (BPD) have produced mixed results. We applied different working memory (WM) measures (Digit Span Forward and Backward, Short-delay and Long-delay CPT-AX, N-back) to patients with SZ (n = 23), psychotic BPD (n = 19) and non-psychotic B...

journal_title：Frontiers in behavioral neuroscience

authors： Frydecka D,Eissa AM,Hewedi DH,Ali M,Drapała J,Misiak B,Kłosińska E,Phillips JR,Moustafa AA

更新日期：2014-11-28 00:00:00

abstract：:In humans, optimism is a cognitive construct related to motivation; optimists exert effort, whereas pessimists disengage from effort. In this study, using a recently developed ambiguous-cue interpretation (ACI) paradigm we took the unique opportunity to investigate whether "optimism" as a trait is correlated with moti...

journal_title：Frontiers in behavioral neuroscience

authors： Rygula R,Golebiowska J,Kregiel J,Kubik J,Popik P

更新日期：2015-02-25 00:00:00

abstract：:Molecular processes in GABAergic local circuit neurons critically contribute to information processing in the hippocampus and to stress-induced activation of the amygdala. In the current study, we determined expression changes in GABA-related factors induced in subregions of the dorsal hippocampus as well as in the BL...

journal_title：Frontiers in behavioral neuroscience

authors： Hadad-Ophir O,Albrecht A,Stork O,Richter-Levin G

更新日期：2014-01-21 00:00:00

abstract：:How a stimulus impacts spinal cord function depends upon temporal relations. When intermittent noxious stimulation (shock) is applied and the interval between shock pulses is varied (unpredictable), it induces a lasting alteration that inhibits adaptive learning. If the same stimulus is applied in a temporally regular...

journal_title：Frontiers in behavioral neuroscience

authors： Lee KH,Huang YJ,Grau JW

更新日期：2016-02-11 00:00:00

abstract：:Somatostatin (SOM) and somatostatin receptors (SSTR1-4) are present in all olfactory structures, including the olfactory bulb (OB), where SOM modulates physiological gamma rhythms and olfactory discrimination responses. In this work, histological, viral tracing and transgenic approaches were used to characterize SOM c...

journal_title：Frontiers in behavioral neuroscience

authors： Nocera S,Simon A,Fiquet O,Chen Y,Gascuel J,Datiche F,Schneider N,Epelbaum J,Viollet C

更新日期：2019-04-09 00:00:00