Abstract:
:This research evaluated the fungistatic and fungicidal activities of red propolis alcoholic extract (RPAE) against different Candida species isolated from chronic periodontitis cases, and compared with chlorhexidine (CHX). Nineteen samples of Candida species (C. albicans [n = 12], C. tropicalis [n = 5] and C. glabrata [n = 2]) isolated from chronic periodontitis cases were analyzed. The fungistatic and fungicidal activity of both RPAE and CHX were evaluated using fluconazole and C. parapsilosis (ATCC 6258) as a control. Fungistatic activity was analyzed based on the Clinical and Laboratory Standards Institute (CLSI) reference procedure to determine the minimum inhibitory concentrations. Fungicidal activity was established according to the absence of fungal growth on Sabouraud Dextrose Agar medium. The fungistatic and fungicidal activities of RPAE were observed, respectively, at 32-64 μg/mL and 64-512 μg/mL for C. albicans, 64 μg/mL and 64-256 μg/mL for C. glabrata, and 32-64 μg/mL and 64 µg/mL for C. tropicalis. CHX fungistatic activity was observed at concentrations of 0.003-1.92 µg/mL for C. albicans, 1.92 µg/mL for C. glabrata, and 0.03-1.92 µg/mL for C. tropicalis. Fluconazole fungistatic activity ranged between 1-64 μg/mL, and fungicidal activity occurred at 8-64 μg/mL, for the three Candida species analyzed. All the Candida species were susceptible to RPAE antifungal activity, but five samples of C. albicans, one of C. tropicalis and one of C. glabrata were resistant to fluconazole antifungal activity. CHX showed fungistatic activity against all the Candida species analyzed. The antifungal potential of these substances suggests that they can be applied as an alternative treatment for diseases affected by these species.
journal_name
Braz Oral Resjournal_title
Brazilian oral researchauthors
Siqueira AB,Rodriguez LR,Santos RK,Marinho RR,Abreu S,Peixoto RF,Gurgel BCdoi
10.1590/1807-3107BOR-2015.vol29.0083subject
Has Abstractpub_date
2015-01-01 00:00:00eissn
1806-8324issn
1807-3107pii
S1806-83242015000100278journal_volume
29pub_type
杂志文章abstract::The purpose of this double-blind, randomized, crossover in situ study is to compare remineralization of preformed enamel lesions by casein phosphopeptide-stabilized amorphous calcium phosphate (CPP-ACP) and fluoride dentifrice products. During each of four 10-day experimental legs, 10 participants wore intraoral remov...
journal_title:Brazilian oral research
pub_type: 杂志文章,随机对照试验
doi:10.1590/1807-3107bor-2020.vol34.0061
更新日期:2020-06-24 00:00:00
abstract::Based on aroeira's (Myracrodruon urundeuva) antimicrobial activity and a future trend to compose intracanal medication, the aim of this study was to assess in vivo inflamatory tissue response to the extracts by edemogenic and histological analysis containing inactivated facultative and anaerobic microorganisms. For ed...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2018.vol32.0042
更新日期:2018-05-24 00:00:00
abstract::Dental treatment and surgery is a well-established method of correcting dentofacial deformities, and such treatment has an impact on the quality of life of individuals. The objective of this study was to evaluate the effect of orthognathic surgery on the quality of life of patients receiving treatment at the Universid...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107BOR-2016.vol30.0004
更新日期:2016-01-01 00:00:00
abstract::In spite of decades of research on fluoride and the recognition of its role as the cornerstone of dental caries reduction in the last fifty years, questions still arise on its use at community, self-applied and professional application levels. Which method of fluoride delivery should be used? How and when should it be...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242010000500003
更新日期:2010-01-01 00:00:00
abstract::The purpose of this study was to evaluate the inflammatory and cure events of acid-based reactions using glass ionomer cement used for cementation of crowns, bridges, onlays and orthodontic bands implanted in subcutaneous tissue, at different time intervals. A total of 48 male Wistar rats were used, distributed into 4...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/S1806-83242014.50000003
更新日期:2014-01-01 00:00:00
abstract::We reviewed the literature to evaluate: a) The compliance of randomized clinical trials (RCTs) on bleaching with the CONSORT; and b) the risk of bias of these studies using the Cochrane Collaboration risk of bias tool (CCRT). We searched the Cochrane Library, PubMed and other electronic databases, to find RCTs focused...
journal_title:Brazilian oral research
pub_type: 杂志文章,评审
doi:10.1590/1807-3107BOR-2017.vol31.0060
更新日期:2017-08-28 00:00:00
abstract::Poor oral hygiene seems to be the norm in children and teenagers with Down Syndrome (DS). Advances in design and types of toothbrushes may improve biofilm control. This randomized, single-blind, crossover clinical trial evaluated the effectiveness of electric toothbrushes regarding mechanical control of biofilm in chi...
journal_title:Brazilian oral research
pub_type: 杂志文章,随机对照试验
doi:10.1590/1807-3107bor-2020.vol34.0057
更新日期:2020-06-19 00:00:00
abstract::Human Papilomaviruses (HPV) are a group of viruses associated with benign and malignant lesions of cutaneous and mucosal epithelia. Some "high risk" HPV types, especially HPV 16 and 18, are strongly correlated with cervical and anogenital cancers and are also related to the genesis of oral squamous cell carcinomas (OS...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242006000100005
更新日期:2006-01-01 00:00:00
abstract::Although malocclusions represent a serious public health issue, there is insufficient information about this problem in adolescents in Brazil, especially in poorer areas. The purpose of this cross-sectional study was to estimate the prevalence of facial alterations, dental malocclusions, and deleterious oral habits (D...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242012005000027
更新日期:2013-01-01 00:00:00
abstract::The purpose of the present study was to evaluate the relationship between psychological variables and the clinical diagnosis of temporomandbular disorders (TMD) in 12-year-old adolescents. TMD pain was assessed by RDC/TMD examination (Research Diagnostic Criteria for Temporomandibular Disorders) (Axis I and II). Five-...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242009000200011
更新日期:2009-04-01 00:00:00
abstract::The extent of separation between the maxillary and mandibular teeth in the fabrication of interocclusal splints designed to achieve efficiency and muscle relaxation is controversial and undefined in the literature. Based on this premise, the aim of this study was to evaluate the effect of interocclusal splint thicknes...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242011000600006
更新日期:2011-11-01 00:00:00
abstract::Candida infection is an important cause of morbidity and mortality in immunocompromised patients. The increase in its incidence has been associated with resistance to antimicrobial therapy and biofilm formation. The aim of this study was to evaluate the efficacy of tea tree oil (TTO) and its main component - terpinen-...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2020.vol34.0050
更新日期:2020-06-05 00:00:00
abstract::Over the last decade, there has been growing interest in diagnosing non-cavitated lesions in epidemiological studies involving large numbers of preschool children, schoolchildren and young adults. In this context, assessment of lesions characteristics indicating whether or not there is ongoing mineral loss is also con...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/S1806-83242013005000036
更新日期:2014-01-01 00:00:00
abstract::To assess the impact of oral conditions on the oral health-related quality of life (OHRQoL) of pediatric liver transplant candidates. This cross-sectional study included 60 children aged 13 to 48 months who were liver transplant candidates that attended the AC Camargo Cancer Center, São Paulo, Brazil. On the day of or...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2020.vol34.0100
更新日期:2020-01-01 00:00:00
abstract::This study aimed at assessing the relationship between dental pain and the reason for using dental services and oral health quality of life in people aged 50 to 74 years in southern Brazil. A cross-sectional population-based study was conducted with 720 individuals aged 50 to 74 years, living in three health districts...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107BOR-2016.vol30.0039
更新日期:2016-08-18 00:00:00
abstract::Dental trauma in immature permanent teeth can damage pulp vascularization, which leads to necrosis and cessation of apexogenesis. Studies on tissue engineering using stem cells from human exfoliated deciduous teeth (SHEDs) have yielded promising results. Laser phototherapy (LPT) is able to influence the proliferation ...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107BOR-2016.vol30.0080
更新日期:2016-05-31 00:00:00
abstract::Periodontal diseases are considered a worldwide public health problem, owing to their high prevalence in developed and developing countries. Periodontitis may lead to tooth loss, which can impact oral health-related quality of life. Gingivitis and periodontitis have been extensively studied regarding their etiopathoge...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2020.vol34.0027
更新日期:2020-04-09 00:00:00
abstract::The aim of this study was to analyze the efficiency of experimental light-curing resin cements (ERCs) with a ternary photo-initiator system containing diphenyliodonium hexafluorphosphate (DPI) and different amines on retention of glass-fiber posts to dentin (GFP). ERCs formulations: a 1:1 mass ratio of 2,2-bis[4-(2-hy...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2018.vol32.0116
更新日期:2018-11-14 00:00:00
abstract::The objective of this study was to evaluate the influence of different surface agents on the flexural strength of a ceramic system. Eighty bar-shaped specimens of zirconia were divided into four groups according to the agent to be used: group Control--to be cleaned with alcohol; group VM9--application of a fluid layer...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242013000400004
更新日期:2013-07-01 00:00:00
abstract::This research evaluated the bone repair process in surgical defects created on the parietal bones of diabetic rabbits using the guided bone regeneration technique to observe the effects of alloxan in the induction of diabetes mellitus. Twenty-four adult rabbits were divided into three study groups: control (C), diabet...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242008000200015
更新日期:2008-04-01 00:00:00
abstract::Conventional methods of caries detection, including the gold standard of histological examination, have certain disadvantages that must be addressed prior to validating any other diagnostic technique-current or new. Here we evaluated the validity of micro-computed tomography (micro-CT) as an alternative gold-standard ...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107BOR-2015.vol29.0132
更新日期:2015-01-01 00:00:00
abstract::The cyclic resistance of ProTaper Universal (size 25/08) and ProTaper Next (size 25/06) instruments was compared in artificial canals with different curvatures in this study. A total of 30 ProTaper Universal and 30 ProTaper Next instruments were divided into 6 groups (n = 10) and were operated into artificial canals w...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107BOR-2015.vol29.0122
更新日期:2015-01-01 00:00:00
abstract::The aim of this study was to establish two new formulas for objectively evaluating skeletal maturation of cervical vertebrae in female and male Brazilian subjects using lateral cephalometric radiographs. The sample included 128 girls and 110 boys, aged 7.0 to 15.9 years, from the files of the Oral Radiology Clinic, Pi...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242007000400009
更新日期:2007-10-01 00:00:00
abstract::This study aimed to evaluate the role of photobiomodulation (PBM) in apexification and apexogenesis of necrotic rat molars with an open apex. Rat molars were exposed to the oral environment for 3 weeks. Canals were rinsed with 2.5% NaOCl and 17% EDTA, filled with antibiotic paste and sealed. After 7 days, canals were ...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2019.vol33.0084
更新日期:2019-08-26 00:00:00
abstract::The aim of this study was to evaluate changes in the superficial dentin pattern of primary teeth after applying different phosphoric acid concentrations and conditioning times. Twenty-four dentin surfaces were divided in 4 groups with 10 teeth each: GI -no treatment; GII to GIV -phosphoric acid at 37%, 32%, and 10% re...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242010000300011
更新日期:2010-07-01 00:00:00
abstract::The goal of this study was to evaluate skeletal, dental and chronological development in an HIV-positive group of children, as compared with a control group, during a four-year period. Panoramic radiographs and hand and wrist radiographs of 60 children were taken. The children, of both sexes, aged 5 years and 2 months...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/s1806-83242005000300010
更新日期:2005-07-01 00:00:00
abstract::This study evaluated the effects of 10% alphatocopherol on the fracture resistance of endodontically treated teeth subjected to tooth bleaching with hydrogen peroxide and immediately restored with composite resin. Fifty bovine incisors were selected, including 10 sound teeth that constituted the control group (G1 (C))...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107BOR-2016.vol30.0069
更新日期:2016-05-20 00:00:00
abstract::The aim of this study is to evaluate the expression of cytokines in response to mineral trioxide aggregate (MTA) plus selenium in germ-free mice with experimental furcal perforation. The first left maxillary molar was opened, and the furcal area was perforated and treated with post-MTA-Se (experimental group). The sam...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2018.vol32.0103
更新日期:2018-10-11 00:00:00
abstract::This study evaluated the effect of implantoplasty on different bone insertion levels of exposed implants. A model of the Bone Level Tapered implant (Straumann Institute, Waldenburg, Switzerland) was created through the Rhinoceros software (version 5.0 SR8, McNeel North America, Seattle, WA, USA). The abutment was fixe...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107bor-2017.vol31.0096
更新日期:2017-12-07 00:00:00
abstract::The bond strength of methacrylate (Z350, 3M ESPE) and silorane (P90, 3M ESPE) restorations, using different cavity filling techniques, was investigated. Cavities (6 × 3 × 3) in bovine teeth were filled using bulk, oblique, or horizontal increments. A push-out test was carried out after 24 h. Data were statistically an...
journal_title:Brazilian oral research
pub_type: 杂志文章
doi:10.1590/1807-3107BOR-2016.vol30.0044
更新日期:2016-01-01 00:00:00