Abstract:
BACKGROUND:Clinical schistosomiasis in endemic countries is treated with a single dose of praziquantel per 40 mg/kg body weight. Treating according to weight, in resource-poor settings when thousands of doses are to be administered in mass treatment campaigns, is considered problematic. A calibrated dose-pole based on height was developed and is now used in mass treatment campaigns for determining the doses for schoolchildren. The dose-pole will generate dose errors since every child population contains individuals that are either short or tall for weight. The aim of this study is to explore whether the WHO praziquantel pole is a satisfactory dose instrument for mass treatment of S. haematobium. METHODS:In 1996 and 2002, 1,694 children were surveyed in the Kilimanjaro Region, Tanzania. We compared doses given by weight to doses given by height using descriptive statistics and regression. CONCLUSIONS AND INTERPRETATION:The WHO dose-pole for praziquantel is based on height of the patient; however, children with the same height will differ in weight. Our study shows that children with the same weight could qualify for up to four different dose levels based on their height. The largest variation of doses based on the WHO dose-pole will be found in children below 20 kg of bodyweight. Using bodyweight and tablet halves as the smallest tablet division unit to determine the doses of praziquantel, one only has to identify every 6th kilogram of bodyweight; the doses will then vary a lot less than when using the WHO dose-pole.
journal_name
Glob Health Actionjournal_title
Global health actionauthors
Nordin P,Poggensee G,Mtweve S,Krantz Idoi
10.3402/gha.v7.25351subject
Has Abstractpub_date
2014-12-03 00:00:00pages
25351eissn
1654-9716issn
1654-9880pii
25351journal_volume
7pub_type
杂志文章abstract:BACKGROUND:There is a dearth of empirical research illuminating possible connections between gender imbalances and sexual violence among married women in Tanzania. There is a need to generate in-depth information on the connectivity between gender imbalances (asymmetrical resource ownership, sexual decision making, rol...
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v7.25346
更新日期:2014-12-05 00:00:00
abstract:BACKGROUND:Legal empowerment of the poor is highly relevant to public health as it aims to relieve income poverty, a main determinant of health. The Commission on Legal Empowerment of the Poor (CLEP) has proposed legal empowerment measures in the following four domains: access to justice and the rule of law, property, ...
journal_title:Global health action
pub_type: 杂志文章,评审
doi:10.3402/gha.v6i0.22854
更新日期:2013-11-15 00:00:00
abstract:BACKGROUND:Mortality in a population may be clustered in space and time for a variety of reasons, including geography, socio-economics, environment and demographics. Analysing mortality clusters can therefore reveal important insights into patterns and risks of mortality in a particular setting. OBJECTIVE AND DESIGN:T...
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v3i0.5244
更新日期:2010-08-30 00:00:00
abstract:BACKGROUND:Intrapartum-related hypoxia accounts for 30% of neonatal deaths in Tanzania. This has led to the introduction and scaling-up of the Helping Babies Breathe (HBB) programme, which is a simulation-based learning programme in newborn resuscitation skills. Studies have documented ineffective ventilation of non-br...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2018.1423862
更新日期:2018-01-01 00:00:00
abstract::Background: Previous research has highlighted the importance of major atmospheric aerosols such as sulfate, through its precursor sulfur dioxide (SO2), black carbon (BC), and organic carbon (OC), and their effect on global climate regimes, specifically on their impact on particulate matter measuring ≤ 2.5 μm (PM2.5). ...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2019.1664130
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Despite the importance of an effective health system response to various disasters, relevant research is still in its infancy, especially in middle- and low-income countries. OBJECTIVE:This paper provides an overview of the status of disaster health management in China, with its aim to promote the effective...
journal_title:Global health action
pub_type: 杂志文章,评审
doi:10.3402/gha.v7.24986
更新日期:2014-09-10 00:00:00
abstract:BACKGROUND:The obesity epidemic has been growing steadily across the whole world, and so far not a single country has been able to reverse it. The cause of obesity is stated by the World Health Organization as an energy imbalance between calories consumed and calories expended. However, growing evidence suggests that t...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2017.1289650
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:In most low and middle-income countries vital events registration for births and child deaths is poor, with reporting of pregnancy outcomes highly inadequate or non-existent. Health and Demographic Surveillance System (HDSS) sites and periodic population-based household-level surveys can be used to identify ...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2017.1356641
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Following the launch of District Health Information System 2 across facilities in Kenya, more health facilities are now capable of carrying out malaria parasitological testing and reporting data as part of routine health information systems, improving the potential value of routine data for accurate and time...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2017.1413266
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Despite the implementation of Directly Observed Treatment Short-course (DOTS) strategy in all public health centers in Papua Province, Indonesia, since 1998, the rate of loss to follow-up (LTFU) during tuberculosis (TB) treatment remains high (above 16%). OBJECTIVES:We aimed to identify factors associated w...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2018.1510592
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The 4-year (2007-2011) Revitalizing Health for All international research program (http://www.globalhealthequity.ca/projects/proj_revitalizing/index.shtml) supported 20 research teams located in 15 low- and middle-income countries to explore the strengths and weaknesses of comprehensive primary health care (...
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v7.24997
更新日期:2014-08-21 00:00:00
abstract:BACKGROUND:Mortality has been declining in Bangladesh since the mid- twentieth century, while fertility has been declining since the late 1970s, and the country is now passing through the third stage of demographic transition. This type of demographic transition has produced a huge youthful population with a growing nu...
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v3i0.4618
更新日期:2010-09-27 00:00:00
abstract:BACKGROUND:The burden of diabetes mellitus in Sub-Saharan Africa is growing rapidly, and yet the prevalence and patient characteristics are still largely unknown. OBJECTIVES:We analyzed clinical and demographic characteristics of Type 2 diabetes (T2DM) patients attending a diabetes clinic in Guinea-Bissau from Februar...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2020.1802136
更新日期:2020-12-31 00:00:00
abstract:BACKGROUND:Individuals in conflict-affected areas rarely get appropriate care for chronic or non-infectious diseases. The prevalence of gestational diabetes mellitus (GDM) is increasing worldwide, and new evidence shows conclusively that the negative effects of hyperglycemia occur even at mild glucose elevations and th...
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v7.23887
更新日期:2014-05-12 00:00:00
abstract:BACKGROUND:Evidence-based interventions for autism spectrum disorders evaluated in high-income countries typically require highly specialised manpower, which is a scarce resource in most low- and middle-income settings. This resource limitation results in most children not having access to evidence-based interventions....
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v8.27278
更新日期:2015-08-03 00:00:00
abstract:BACKGROUND:Adolescents in low and middle-income countries experience pronounced mental health needs in contexts where infrastructure and resources are scarce. While evidence-based treatment are readily available, they may not fit the unique needs of certain contexts. OBJECTIVE:This manuscript illustrates the systemati...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2020.1775062
更新日期:2020-12-31 00:00:00
abstract:BACKGROUND:The collaborative quality improvement approach proposed by the Institute for Healthcare Improvement has the potential to improve coverage of evidence-based maternal and newborn health practices. The Safe Care, Saving Lives initiative supported the implementation of 20 evidence-based maternal and newborn care...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2019.1581466
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Domestic violence during pregnancy has detrimental effects on the health of the mother and the newborn. Antenatal care provides a 'window of opportunity' to identify and assist victims of domestic violence during pregnancy. Little is known about the experience, needs, and expectations from the women's perspe...
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v9.31838
更新日期:2016-12-14 00:00:00
abstract:BACKGROUND:Migrant health workers fill care gaps in their destination countries, but they also actively engage in improving living conditions for people of their countries of origin through expatriate professional networks. This paper aims to explore the professional links that migrant health workers from sub-Saharan A...
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v8.29210
更新日期:2015-12-09 00:00:00
abstract:BACKGROUND:A previous review of early infant diagnosis (EID) using polymerase chain reaction technology (PCR) under integrated HIV care (IHC) program in Myanmar revealed a low uptake of timely (within 6 to 8 weeks of babies' age) EID and a long turnaround time (TAT) of receiving results. OBJECTIVE:This study aimed to ...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2017.1395657
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Like many countries in Southeast Asia, Vietnam's rapid population and economic growth has met challenges in infrastructure development, especially sanitation in rural areas. OBJECTIVE:As an entry point, we developed scenario planning as an action-research tool in a peri-urban community to identify first ste...
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v7.24482
更新日期:2014-08-18 00:00:00
abstract:BACKGROUND:Sexual violence against women and children in Tanzania and globally is a human rights violation and a developmental challenge. OBJECTIVE:The aim of this study was to assess the impact of training health professionals on rape management. The specific objectives were to evaluate the changes of knowledge and a...
journal_title:Global health action
pub_type: 杂志文章,评审
doi:10.3402/gha.v9.31735
更新日期:2016-07-14 00:00:00
abstract::Background: Isoniazid preventive therapy (IPT) has been shown to reduce the risk of tuberculosis (TB) among people living with HIV (PLHIV). In 2017, India began a nationwide roll-out of IPT, but there is a lack of evidence on the implementation and the challenges.Objectives: Among PLHIV newly initiated on antiretrovir...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2019.1704540
更新日期:2020-01-01 00:00:00
abstract::In low- and middle-income countries, nutrition support strategies are often suboptimal or non-existent in hospital settings. This is further compounded by high rates of malnutrition in these countries. The first four dietitians graduated in Malawi in 2017 providing a new opportunity to build capacity to introduce nutr...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2019.1656452
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Oral health affects quality of life and is linked to overall health. Enhanced oral health research is needed in low- and middle-income countries to develop strategies that reduce the burden of oral disease, improve oral health and inform oral health workforce and infrastructure development decisions. OBJECT...
journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2018.1477249
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Although community engagement (CE) is widely used in health promotion, components of CE models associated with improved health are poorly understood. This study aimed to examine the magnitude of the impact of CE on health and health inequalities among disadvantaged populations, which methodological approache...
journal_title:Global health action
pub_type: 杂志文章,评审
doi:10.3402/gha.v8.29842
更新日期:2015-12-18 00:00:00
abstract:BACKGROUND:Assessing the progress in achieving the United Nation's Millennium Development Goals in terms of population health requires consistent and reliable information on cause-specific mortality, which is often rare in resource-constrained countries. Health and demographic surveillance systems (HDSS) have largely u...
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v7.25581
更新日期:2014-10-29 00:00:00
abstract:BACKGROUND:The major chronic non-communicable diseases (NCDs) operate through a cluster of common risk factors, whose presence or absence determines not only the occurrence and severity of the disease, but also informs treatment approaches. Primary prevention based on mitigation of these common risk factors through pop...
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v2i0.1986
更新日期:2009-09-28 00:00:00
abstract:BACKGROUND:The dementia diagnosis gap in sub-Saharan Africa (SSA) is large, partly due to difficulties in assessing function, an essential step in diagnosis. OBJECTIVES:As part of the Identification and Intervention for Dementia in Elderly Africans (IDEA) study, to develop, pilot, and validate an Instrumental Activiti...
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v7.25988
更新日期:2014-12-22 00:00:00
abstract:BACKGROUND:Previous studies have reported an association between cigarette advertising and smoking behavior. Although this has been reported extensively in the West, it has been reported less in Southeast Asian countries that have not completely banned tobacco advertising promotion and sponsorship (TAPS). Indonesia is ...
journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v9.30914
更新日期:2016-08-29 00:00:00