N-3 polyunsaturated fatty acids do not influence the efficacy of dual antiplatelet therapy in stable angina pectoris patients after percutaneous coronary intervention.

Abstract:

BACKGROUND:We aimed to prospectively assess the influence of the recommended dose, 1.0 g of polyunsaturated fatty acids (N-3 PUFA) daily, on platelet reactivity in patients with stable angina pectoris (SAP) after elective percutaneous coronary intervention (PCI). METHODS:Forty consecutive patients with SAP and successful PCI were randomized to the study group (group PUFA: n = 20; age 65 ± 8; standard therapy + 75 mg acetylsalicylic acid + 75 mgclopidogrel + N-3 PUFA/Omacor 1 g daily) and the control group (group C: n = 20; age 65 ± 9; standard therapy + 75 mg acetylsalicylic acid + 75 mg clopidogrel). Platelet reactivity tests (COL, TRAP, ASPI, ADP) were performed using whole blood aggregometry (multiplate platelet [PLT] function analysis) on the 2,nd and 30th day after PCI. RESULTS:Baseline patients' characteristics and clinical outcomes were comparable between the groups. There were no differences between both groups in the mean values of the PTL tests measured 30 days after PCI (PUFA vs. C ASPI:18.5 ± 17 vs. 27 ± 29 U, COL: 30.4 ± 14.3 vs. 30.3 ± 13.4 U, ADP: 25.4 ± 16.1 vs. 20 ± 10.7 U, TRAP: 65.8 ± 25.6 vs. 57.1 ± 20.4 U, p = NS). The mean delta values of the PTL tests (18-24 h post-PCI/30 days post-PCI) were also comparable between the groups. The PTL aggregometry results were related to time - the baseline values of the ADP (p = 0.003), COL (p = 0.037) and TRAP (p < 0.001) tests were smaller and the ASPI (p = 0.027) test was higher than those measured after 1-month. CONCLUSIONS:N-3 PUFA supplementation does not affect the efficacy of dual antiplatelettherapy in patients with SAP after PCI.

journal_name

Cardiol J

journal_title

Cardiology journal

authors

Mizia-Stec K,Mizia M,Haberka M,Lasota B,Gieszczyk-Strózik K,Chmiel A,Najda J,Gąsior Z,Kyrcz-Krzemień S

doi

10.5603/CJ.2013.0132

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

478-85

issue

5

issn

1897-5593

pii

VM/OJS/J/35847

journal_volume

20

pub_type

杂志文章,随机对照试验
  • Effect of LCZ696, a dual angiotensin receptor neprilysin inhibitor, on isoproterenol-induced cardiac hypertrophy, fibrosis, and hemodynamic change in rats.

    abstract:BACKGROUND:Recent clinical studies have shown that treatment with LCZ696, a complex containing the angiotensin receptor blocker valsartan and neprilysin inhibitor sacubitril, improves the prognosis of heart failure patients with a reduced ejection fraction. This study evaluated whether LCZ696 affects left ventricular h...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2018.0048

    authors: Miyoshi T,Nakamura K,Miura D,Yoshida M,Saito Y,Akagi S,Ohno Y,Kondo M,Ito H

    更新日期:2019-01-01 00:00:00

  • Prognostic significance of QRS duration and morphology.

    abstract::QRS duration and morphology, evaluated via a standard 12-lead electrocardiogram (ECG), represent an opportunity to derive useful prognostic information regarding the risk of subsequent cardiac events or therapeutic outcomes. Prolonged QRS duration, and the presence of intraventricular conduction abnormalities, usually...

    journal_title:Cardiology journal

    pub_type: 杂志文章,评审

    doi:

    authors: Brenyo A,Zaręba W

    更新日期:2011-01-01 00:00:00

  • Hormonal profiles behind the heart of a man.

    abstract::This study focuses on the role of sex steroids on the libido, sexual life, emotional and physiological heart of men of all ages. Sex steroids play a significant role throughout a man's life, with a gradual decline in old age. The foetal testis secretes testosterone and dehydroepiandrosterone at about nine weeks gestat...

    journal_title:Cardiology journal

    pub_type: 杂志文章,评审

    doi:

    authors: Sarkar NN

    更新日期:2009-01-01 00:00:00

  • The metabolic syndrome entanglement: Cutting the Gordian knot.

    abstract::Questions have been raised on the clinical value of the metabolic syndrome (MS). The negative opinion regarding MS is anchored basically on a separate analysis of 4 conditions: obesity, dyslipidemia, hypertension and glucose intolerance. The common denominator of these 4 sets of arguments is that they represent an utt...

    journal_title:Cardiology journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.5603/CJ.a2013.0054

    authors: Fisman EZ,Tenenbaum A

    更新日期:2014-01-01 00:00:00

  • Importance of cardiac biomarkers in risk stratification in acute pulmonary embolism.

    abstract::At present there is consent that patients with acute pulmonary embolism (APE) and hemodynamic instability have poor prognosis and benefit from thrombolytic therapy or embolectomy, whereas hemodynamically stable patients without echocardiographic signs of right ventricular overload/dysfunction (RVO) have good prognosis...

    journal_title:Cardiology journal

    pub_type: 杂志文章,评审

    doi:

    authors: Mikulewicz M,Lewczuk J

    更新日期:2008-01-01 00:00:00

  • Evaluation of coronary artery abnormalities in Williams syndrome patients using myocardial perfusion scintigraphy and CT angiography.

    abstract:BACKGROUND:Sudden death risk in Williams syndrome (WS) patients has been shown to be 25-100 times higher than in the general population. This study aims to detect coronary artery anomalies and myocardial perfusion defects in WS patients using noninvasive diagnostic methods. METHODS:This study features 38 patients diag...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/cj.2012.0053

    authors: Ergul Y,Nisli K,Kayserili H,Karaman B,Basaran S,Dursun M,Yilmaz E,Ergul N,Unal SN,Dindar A

    更新日期:2012-01-01 00:00:00

  • The relationship between oxidative stress and coronary artery ectasia.

    abstract:BACKGROUND:Whereas coronary artery ectasia (CAE) is a rare abnormality of the coronary arteries, co-existent coronary artery disease (CAD) is commonly seen in CAE patients. Since a causative relationship has been shown to exist between oxidative stress and CAD, we sought to determine whether any relationship exists bet...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Sezen Y,Bas M,Polat M,Yildiz A,Buyukhatipoglu H,Kucukdurmaz Z,Kaya Z,Demirbag R

    更新日期:2010-01-01 00:00:00

  • Pheochromocytoma-induced reverse tako-tsubo with rapid recovery of left ventricular function.

    abstract::Pheochromocytoma is a rare, catecholamine-secreting tumor of neuroendocrine cells. It has been documented to present atypically as myocardial ischemia, arrhythmias, or congestive heart failure. We present the case of a patient who had transient cardiomyopathy with hypokinesia of the basal portions of the left ventricl...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/cj.2012.0097

    authors: Naderi N,Amin A,Setayesh A,Pouraliakbar H,Mozaffari K,Maleki M

    更新日期:2012-01-01 00:00:00

  • The comparison of contrast echocardiography and tissue Doppler imaging for evaluation of reperfused myocardium in patients with acute anterior myocardial infarction.

    abstract:BACKGROUND:Prediction of functional myocardial recovery post acute myocardial infarction should be based not only on flow patency of the infarct related artery (IRA) but also on the quality of microcirculation in at-risk segments. Myocardial blush grade (MBG) is a method of perfusion assessment which has an established...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Streb W,Duszańska A,Stabryła-Deska J,Pluta S,Swierad M,Was T,Kalarus Z,Kukulski T

    更新日期:2008-01-01 00:00:00

  • Variant rs2200733 and rs10033464 on chromosome 4q25 are associated with increased risk of atrial fibrillation after catheter ablation: Evidence from a meta-analysis.

    abstract:BACKGROUND:Common genetic polymorphisms at chromosome 4q25 were associated with increased susceptibility to atrial fibrillation (AF). However, it remained controversial whether these variants could be used as risk predictors for AF recurrence after catheter ablation. We therefore performed a metaanalysis to quantify th...

    journal_title:Cardiology journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.5603/CJ.a2017.0143

    authors: He J,Zhu W,Yu Y,Hu J,Hong K

    更新日期:2018-01-01 00:00:00

  • Ischemic and non-ischemic patterns of late gadolinium enhancement in heart failure with reduced ejection fraction.

    abstract:BACKGROUND:Late gadolinium enhancement (LGE) by cardiac magnetic resonance (CMR) may reveal myocardial fibrosis which is associated with adverse clinical outcomes in patients undergoing implantable cardioverter-defibrillator (ICD) placement. At the same time, transmural LGE in the posterolateral wall is related to nonr...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2020.0009

    authors: Matusik PS,Bryll A,Matusik PT,Popiela TJ

    更新日期:2020-02-10 00:00:00

  • The relationship between functional capacity and ultrasonic tissue characterization in patients with idiopathic dilated cardiomyopathy.

    abstract:BACKGROUND:Ultrasonic tissue characterization (UTC) has been widely used to investigate left ventricular (LV) dysfunction in various cardiac disorders. The aim of this study was to investigate the correlation between functional capacity and UTC in patients with idiopathic dilated cardiomyopathy (IDCM). METHODS AND RES...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.2013.0082

    authors: Yildiz A,Karakas MF,Cimen T,Tuncez A,Korkmaz A,Uygur B,Isleyen A,Tufekcioglu O

    更新日期:2013-01-01 00:00:00

  • Cryoballoon ablation of atrial fibrillation: How important is the proper selection of patients?

    abstract:BACKGROUND:Relation between pre-procedural selection of patients and the success rate after a single cryoballoon ablation (CAB) procedure is unknown. METHODS:CAB was performed in 378 (65% male, median age 58 years, 85% paroxysmal atrial fibrillation [AF]) consecutive patients with symptomatic and drug refractory AF. T...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2014.0100

    authors: Wójcik M,Berkowitsch A,Zaltsberg S,Hamm CW,Pitschner HF,Kuniss M,Neumann T

    更新日期:2015-01-01 00:00:00

  • The early variation of left ventricular twisting function in patients with lymphoma received anthracycline therapy assessed by three-dimensional speckle tracking echocardiography.

    abstract:BACKGROUND:Anthracycline-induced cardiotoxicity remains a significant and unresolved issue in patients receiving chemotherapy. The aim of this study was to evaluate left ventricular (LV) twisting function by three-dimensional speckle tracking echocardiography (3D-STE) in patients with lymphoma after anthracycline thera...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2017.0035

    authors: Song F,Kang Y,Zhang C,Xu Y,Shi J,Guo Y,Zhang Q,Shu X,Cheng L

    更新日期:2017-01-01 00:00:00

  • Evaluation of a direct access cardiac arrhythmia monitoring service.

    abstract:BACKGROUND:This paper describes the clinical outcomes from a novel direct access arrhythmia monitoring service. METHODS:The study was carried out in the north of Scotland. Data was collected over a 29 month period between 18 June 2008 and 8 November 2010 from consecutive cases from two groups of patients, general prac...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/cj.2012.0010

    authors: Skipsey DA,Dawson FM,Breen C,Leslie SJ

    更新日期:2012-01-01 00:00:00

  • Successful coronary stent retrieval from the renal artery.

    abstract::Coronary stent loss and its migration is one of complications of percutaneous coronary interventions (PCI). We present a case of successful retrieval of a coronary stent which moved initially to the left renal artery. Subsequently the stent was lost again and migrated to the left deep femoral artery, while an attempt ...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Juszkat R,Dziarmaga M,Zabicki B,Bychowiec B

    更新日期:2007-01-01 00:00:00

  • A broken heart in a broken car.

    abstract::Takotsubo syndrome (TTS) is still a relatively understudied and often undetected disease. It is usually preceded by emotional or physical triggers. We here report a case of TTS following a car accident. Typical apical ballooning with moderate reduction of left ventricular ejection fraction (LVEF) and increased level o...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.2016.0034

    authors: Schlossbauer SA,Ghadri JR,Cammann VL,Maier W,Lüscher TF,Templin C

    更新日期:2016-01-01 00:00:00

  • A review of the utility of a hypothermia protocol in cardiac arrests due to non-shockable rhythms.

    abstract:BACKGROUND:Therapeutic hypothermia and targeted temperature management are considered standard of care in the management of patients following out-of-hospital cardiac arrests due to shockable rhythms to improve neurological outcomes. In those presenting out-of-hospital cardiac arrests associated with non-shockable rhyt...

    journal_title:Cardiology journal

    pub_type: 杂志文章,评审

    doi:10.5603/CJ.a2017.0016

    authors: Freund B,Kaplan PW

    更新日期:2017-01-01 00:00:00

  • Myocardial infarction in a low risk patient with hereditary hemorrhagic telangiectasia.

    abstract::We describe the case of a 57 year-old woman with NSTE ACS, a history of recurrent and prolonged epistaxis, and low prior cardiovascular risk. Additional findings revealed anemia and an aneurysm in her central nervous system. During her hospital stay, hereditary hemorrhagic telangiectasia (HHT) was diagnosed. After app...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Janion M,Brzyzkiewicz H,Siuda M,Domagała S,Karliński M

    更新日期:2010-01-01 00:00:00

  • Cardiac resynchronization therapy and atrial fibrillation.

    abstract::Cardiac resynchronization therapy (CRT) is an important advance for the treatment of end-stage heart failure (HF). About 15-50% of HF is complicated by atrial fibrillation (AF), associated with worsened outcomes. The presence of AF may interfere with optimal delivery of CRT due to competition with biventricular (BiV) ...

    journal_title:Cardiology journal

    pub_type: 杂志文章,评审

    doi:

    authors: Kamath GS,Steinberg JS

    更新日期:2009-01-01 00:00:00

  • Twelve-month follow-up of left atrial appendage occlusion with Amplatzer Amulet.

    abstract:BACKGROUND:The Amplatzer Amulet (St. Jude Medical, Minneapolis, MN, USA) is a second gen-eration Amplatzer device for left atrial appendage (LAA) occlusion (LAAO) for stroke prophylaxis in patients with atrial fibrillation. This research sought to assess the clinical performance of the Amplatzer Amulet device and in fo...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2017.0017

    authors: Kleinecke C,Park JW,Gödde M,Zintl K,Schnupp S,Brachmann J

    更新日期:2017-01-01 00:00:00

  • Learning curve in circular multipolar phased radiofrequency ablation of atrial fibrillation.

    abstract:BACKGROUND:Although atrial fibrillation (AF) ablation is considered a technically challenging procedure, studies on the learning curve of different pulmonary vein isolation (PVI) techniques are limited. We investigated the time-dependent changes in procedural parameters, complication rates, and in the 1-year clinical o...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2014.0085

    authors: Martirosyan M,Kiss A,Nagy-Baló E,Sándorfi G,Tint D,Édes I,Csanádi Z

    更新日期:2015-01-01 00:00:00

  • Identification of a peripheral blood long non-coding RNA (Upperhand) as a potential diagnostic marker of coronary artery disease.

    abstract:BACKGROUND:Long non-coding RNAs (lncRNAs) have been confirmed to be involved in the pathologi-cal processes of multiple diseases. However, the characteristic expression of lncRNAs in peripheral blood of coronary artery disease (CAD) patients and whether some of these lncRNAs can be used as diagnostic biomarkers for CAD...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2017.0133

    authors: Li X,Zhao Z,Gao C,Rao L,Hao P,Jian D,Li W,Tang H,Li M

    更新日期:2018-01-01 00:00:00

  • Long time clinical outcomes of limus-eluting stent versus paclitaxel-eluting stent in patients undergoing percutaneous coronary artery intervention: A meta-analysis of randomized controlled clinical trials.

    abstract:BACKGROUND:The meta-analysis was aimed to compare the long time (> 2 year) clinical outcomes of limus-based stents (LBS) and paclitaxel-eluting stents (PES). LBS and PES are two kinds of most common coronary artery stents in clinics. METHODS:Electronic data bases of PubMed, Cochrane, and EMBASE were searched. We inclu...

    journal_title:Cardiology journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.5603/CJ.a2014.0004

    authors: Gao L,Hu X,Hou Y,Xue Q

    更新日期:2014-01-01 00:00:00

  • Intrapericardial paraganglioma: The role of integrated advanced multi-modality cardiac imaging for the assessment and management of rare primary cardiac tumors.

    abstract::N/A. ...

    journal_title:Cardiology journal

    pub_type: 信件

    doi:10.5603/CJ.2017.0091

    authors: Degrauwe S,Monney P,Qanadli SD,Prior J,Beigelmann-Aubry C,Masci PG,Eeckhout E,Muller O,Iglesias JF

    更新日期:2017-01-01 00:00:00

  • Risk of left atrial appendage thrombus in patients with atrial fibrillation and chronic kidney disease.

    abstract:BACKGROUND:Atrial fibrillation (AF) and chronic kidney disease (CKD) are associated with an increased risk of ischemic stroke. The aim of this study was to compare the clinical characteristics, the incidence of left atrial appendage (LAA) thrombus and its predictors, and spontaneous echo contrast (SEC) in a population ...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2020.0036

    authors: Budnik M,Gawałko M,Gorczyca I,Uziębło-Życzkowska B,Krzesiński P,Kochanowski J,Scisło P,Michalska A,Jelonek O,Starzyk K,Jurek A,Kiliszek M,Wożakowska-Kapłon B,Gielerak G,Filipiak KJ,Opolski G,Kapłon-Cieślicka A

    更新日期:2020-04-27 00:00:00

  • Sick euthyroid syndrome is associated with poor prognosis in patients with ST segment elevation myocardial infarction undergoing primary percutaneous intervention.

    abstract:BACKGROUND:Concomitant thyroid and heart disease are frequently encountered in clinical practice. There are many studies evaluating thyroid function in acute and critical conditions. Information on thyroid dysfunction in ST-segment elevation myocardial infarction (STEMI) is limited; its correlation with short and long-...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2013.0108

    authors: Özcan KS,Osmonov D,Toprak E,Güngör B,Tatlısu A,Ekmekçi A,Kaya A,Tayyareci G,Erdinler İ

    更新日期:2014-01-01 00:00:00

  • The treatment of acute myocardial infarction due to the occlusion of the left main coronary disease.

    abstract::Acute myocardial infarction (AMI) due to the occlusion of the left main coronary artery (LMCA) is a rare but serious condition in the era of percutaneus coronary intervention (PCI). Even more rare is AMI involved with both LMCA and its branches like trifurcartion or bifurcation: this is challenging for interventional ...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Can MM,Tanboga H,Karabay CY,Güler A,Akgun T,Turkyilmaz E,Ozveren O,Mutlu B

    更新日期:2011-01-01 00:00:00

  • Prasugrel overcomes high on-clopidogrel platelet reactivity in the acute phase of acute coronary syndrome and maintains its antiplatelet potency at 30-day follow-up.

    abstract:BACKGROUND:The aim of this study was to assess antiplatelet effect of prasugrel in acute coronary syndrome (ACS) patients with high on-treatment platelet reactivity (HTPR) on clopidogrel, undergoing percutaneous coronary intervention (PCI). METHODS:A prospective, platelet reactivity-guided, parallel-group, open-label ...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2014.0026

    authors: Koziński M,Obońska K,Stankowska K,Navarese EP,Fabiszak T,Stolarek W,Kasprzak M,Siller-Matula JM,Rość D,Kubica J,De Servi S

    更新日期:2014-01-01 00:00:00

  • Predicted and observed in-hospital mortality after left main coronary artery stenting in 204 patients.

    abstract:BACKGROUND:The purpose of this study was to compare risk predicted using available risk scores and actual outcomes in patients with left main coronary artery disease undergoing percutaneous coronary intervention with stent implantation (PCI LM). METHODS:We studied 204 patients treated with elective or emergent coronar...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Sukiennik A,Ostrowska-Nowak J,Wiśniewska-Szmyt J,Radomski M,Rychter M,Jabłoński M,Białoszyński T,Koziński M,Fabiszak T,Dobosiewicz R,Zabielska E,Sukiennik T,Kubica A,Król A,Demidowicz K,Chojnicki M,Grabczewska Z,Swiatki

    更新日期:2008-01-01 00:00:00