Abstract:
BACKGROUND:We aimed to prospectively assess the influence of the recommended dose, 1.0 g of polyunsaturated fatty acids (N-3 PUFA) daily, on platelet reactivity in patients with stable angina pectoris (SAP) after elective percutaneous coronary intervention (PCI). METHODS:Forty consecutive patients with SAP and successful PCI were randomized to the study group (group PUFA: n = 20; age 65 ± 8; standard therapy + 75 mg acetylsalicylic acid + 75 mgclopidogrel + N-3 PUFA/Omacor 1 g daily) and the control group (group C: n = 20; age 65 ± 9; standard therapy + 75 mg acetylsalicylic acid + 75 mg clopidogrel). Platelet reactivity tests (COL, TRAP, ASPI, ADP) were performed using whole blood aggregometry (multiplate platelet [PLT] function analysis) on the 2,nd and 30th day after PCI. RESULTS:Baseline patients' characteristics and clinical outcomes were comparable between the groups. There were no differences between both groups in the mean values of the PTL tests measured 30 days after PCI (PUFA vs. C ASPI:18.5 ± 17 vs. 27 ± 29 U, COL: 30.4 ± 14.3 vs. 30.3 ± 13.4 U, ADP: 25.4 ± 16.1 vs. 20 ± 10.7 U, TRAP: 65.8 ± 25.6 vs. 57.1 ± 20.4 U, p = NS). The mean delta values of the PTL tests (18-24 h post-PCI/30 days post-PCI) were also comparable between the groups. The PTL aggregometry results were related to time - the baseline values of the ADP (p = 0.003), COL (p = 0.037) and TRAP (p < 0.001) tests were smaller and the ASPI (p = 0.027) test was higher than those measured after 1-month. CONCLUSIONS:N-3 PUFA supplementation does not affect the efficacy of dual antiplatelettherapy in patients with SAP after PCI.
journal_name
Cardiol Jjournal_title
Cardiology journalauthors
Mizia-Stec K,Mizia M,Haberka M,Lasota B,Gieszczyk-Strózik K,Chmiel A,Najda J,Gąsior Z,Kyrcz-Krzemień Sdoi
10.5603/CJ.2013.0132subject
Has Abstractpub_date
2013-01-01 00:00:00pages
478-85issue
5issn
1897-5593pii
VM/OJS/J/35847journal_volume
20pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Recent clinical studies have shown that treatment with LCZ696, a complex containing the angiotensin receptor blocker valsartan and neprilysin inhibitor sacubitril, improves the prognosis of heart failure patients with a reduced ejection fraction. This study evaluated whether LCZ696 affects left ventricular h...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0048
更新日期:2019-01-01 00:00:00
abstract::QRS duration and morphology, evaluated via a standard 12-lead electrocardiogram (ECG), represent an opportunity to derive useful prognostic information regarding the risk of subsequent cardiac events or therapeutic outcomes. Prolonged QRS duration, and the presence of intraventricular conduction abnormalities, usually...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:
更新日期:2011-01-01 00:00:00
abstract::This study focuses on the role of sex steroids on the libido, sexual life, emotional and physiological heart of men of all ages. Sex steroids play a significant role throughout a man's life, with a gradual decline in old age. The foetal testis secretes testosterone and dehydroepiandrosterone at about nine weeks gestat...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:
更新日期:2009-01-01 00:00:00
abstract::Questions have been raised on the clinical value of the metabolic syndrome (MS). The negative opinion regarding MS is anchored basically on a separate analysis of 4 conditions: obesity, dyslipidemia, hypertension and glucose intolerance. The common denominator of these 4 sets of arguments is that they represent an utt...
journal_title:Cardiology journal
pub_type: 杂志文章,meta分析,评审
doi:10.5603/CJ.a2013.0054
更新日期:2014-01-01 00:00:00
abstract::At present there is consent that patients with acute pulmonary embolism (APE) and hemodynamic instability have poor prognosis and benefit from thrombolytic therapy or embolectomy, whereas hemodynamically stable patients without echocardiographic signs of right ventricular overload/dysfunction (RVO) have good prognosis...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Sudden death risk in Williams syndrome (WS) patients has been shown to be 25-100 times higher than in the general population. This study aims to detect coronary artery anomalies and myocardial perfusion defects in WS patients using noninvasive diagnostic methods. METHODS:This study features 38 patients diag...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2012.0053
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Whereas coronary artery ectasia (CAE) is a rare abnormality of the coronary arteries, co-existent coronary artery disease (CAD) is commonly seen in CAE patients. Since a causative relationship has been shown to exist between oxidative stress and CAD, we sought to determine whether any relationship exists bet...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::Pheochromocytoma is a rare, catecholamine-secreting tumor of neuroendocrine cells. It has been documented to present atypically as myocardial ischemia, arrhythmias, or congestive heart failure. We present the case of a patient who had transient cardiomyopathy with hypokinesia of the basal portions of the left ventricl...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2012.0097
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Prediction of functional myocardial recovery post acute myocardial infarction should be based not only on flow patency of the infarct related artery (IRA) but also on the quality of microcirculation in at-risk segments. Myocardial blush grade (MBG) is a method of perfusion assessment which has an established...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Common genetic polymorphisms at chromosome 4q25 were associated with increased susceptibility to atrial fibrillation (AF). However, it remained controversial whether these variants could be used as risk predictors for AF recurrence after catheter ablation. We therefore performed a metaanalysis to quantify th...
journal_title:Cardiology journal
pub_type: 杂志文章,meta分析,评审
doi:10.5603/CJ.a2017.0143
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Late gadolinium enhancement (LGE) by cardiac magnetic resonance (CMR) may reveal myocardial fibrosis which is associated with adverse clinical outcomes in patients undergoing implantable cardioverter-defibrillator (ICD) placement. At the same time, transmural LGE in the posterolateral wall is related to nonr...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2020.0009
更新日期:2020-02-10 00:00:00
abstract:BACKGROUND:Ultrasonic tissue characterization (UTC) has been widely used to investigate left ventricular (LV) dysfunction in various cardiac disorders. The aim of this study was to investigate the correlation between functional capacity and UTC in patients with idiopathic dilated cardiomyopathy (IDCM). METHODS AND RES...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2013.0082
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Relation between pre-procedural selection of patients and the success rate after a single cryoballoon ablation (CAB) procedure is unknown. METHODS:CAB was performed in 378 (65% male, median age 58 years, 85% paroxysmal atrial fibrillation [AF]) consecutive patients with symptomatic and drug refractory AF. T...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2014.0100
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Anthracycline-induced cardiotoxicity remains a significant and unresolved issue in patients receiving chemotherapy. The aim of this study was to evaluate left ventricular (LV) twisting function by three-dimensional speckle tracking echocardiography (3D-STE) in patients with lymphoma after anthracycline thera...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0035
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:This paper describes the clinical outcomes from a novel direct access arrhythmia monitoring service. METHODS:The study was carried out in the north of Scotland. Data was collected over a 29 month period between 18 June 2008 and 8 November 2010 from consecutive cases from two groups of patients, general prac...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2012.0010
更新日期:2012-01-01 00:00:00
abstract::Coronary stent loss and its migration is one of complications of percutaneous coronary interventions (PCI). We present a case of successful retrieval of a coronary stent which moved initially to the left renal artery. Subsequently the stent was lost again and migrated to the left deep femoral artery, while an attempt ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Takotsubo syndrome (TTS) is still a relatively understudied and often undetected disease. It is usually preceded by emotional or physical triggers. We here report a case of TTS following a car accident. Typical apical ballooning with moderate reduction of left ventricular ejection fraction (LVEF) and increased level o...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2016.0034
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Therapeutic hypothermia and targeted temperature management are considered standard of care in the management of patients following out-of-hospital cardiac arrests due to shockable rhythms to improve neurological outcomes. In those presenting out-of-hospital cardiac arrests associated with non-shockable rhyt...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:10.5603/CJ.a2017.0016
更新日期:2017-01-01 00:00:00
abstract::We describe the case of a 57 year-old woman with NSTE ACS, a history of recurrent and prolonged epistaxis, and low prior cardiovascular risk. Additional findings revealed anemia and an aneurysm in her central nervous system. During her hospital stay, hereditary hemorrhagic telangiectasia (HHT) was diagnosed. After app...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::Cardiac resynchronization therapy (CRT) is an important advance for the treatment of end-stage heart failure (HF). About 15-50% of HF is complicated by atrial fibrillation (AF), associated with worsened outcomes. The presence of AF may interfere with optimal delivery of CRT due to competition with biventricular (BiV) ...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The Amplatzer Amulet (St. Jude Medical, Minneapolis, MN, USA) is a second gen-eration Amplatzer device for left atrial appendage (LAA) occlusion (LAAO) for stroke prophylaxis in patients with atrial fibrillation. This research sought to assess the clinical performance of the Amplatzer Amulet device and in fo...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0017
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Although atrial fibrillation (AF) ablation is considered a technically challenging procedure, studies on the learning curve of different pulmonary vein isolation (PVI) techniques are limited. We investigated the time-dependent changes in procedural parameters, complication rates, and in the 1-year clinical o...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2014.0085
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Long non-coding RNAs (lncRNAs) have been confirmed to be involved in the pathologi-cal processes of multiple diseases. However, the characteristic expression of lncRNAs in peripheral blood of coronary artery disease (CAD) patients and whether some of these lncRNAs can be used as diagnostic biomarkers for CAD...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0133
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The meta-analysis was aimed to compare the long time (> 2 year) clinical outcomes of limus-based stents (LBS) and paclitaxel-eluting stents (PES). LBS and PES are two kinds of most common coronary artery stents in clinics. METHODS:Electronic data bases of PubMed, Cochrane, and EMBASE were searched. We inclu...
journal_title:Cardiology journal
pub_type: 杂志文章,meta分析,评审
doi:10.5603/CJ.a2014.0004
更新日期:2014-01-01 00:00:00
abstract::N/A. ...
journal_title:Cardiology journal
pub_type: 信件
doi:10.5603/CJ.2017.0091
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Atrial fibrillation (AF) and chronic kidney disease (CKD) are associated with an increased risk of ischemic stroke. The aim of this study was to compare the clinical characteristics, the incidence of left atrial appendage (LAA) thrombus and its predictors, and spontaneous echo contrast (SEC) in a population ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2020.0036
更新日期:2020-04-27 00:00:00
abstract:BACKGROUND:Concomitant thyroid and heart disease are frequently encountered in clinical practice. There are many studies evaluating thyroid function in acute and critical conditions. Information on thyroid dysfunction in ST-segment elevation myocardial infarction (STEMI) is limited; its correlation with short and long-...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2013.0108
更新日期:2014-01-01 00:00:00
abstract::Acute myocardial infarction (AMI) due to the occlusion of the left main coronary artery (LMCA) is a rare but serious condition in the era of percutaneus coronary intervention (PCI). Even more rare is AMI involved with both LMCA and its branches like trifurcartion or bifurcation: this is challenging for interventional ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess antiplatelet effect of prasugrel in acute coronary syndrome (ACS) patients with high on-treatment platelet reactivity (HTPR) on clopidogrel, undergoing percutaneous coronary intervention (PCI). METHODS:A prospective, platelet reactivity-guided, parallel-group, open-label ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2014.0026
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to compare risk predicted using available risk scores and actual outcomes in patients with left main coronary artery disease undergoing percutaneous coronary intervention with stent implantation (PCI LM). METHODS:We studied 204 patients treated with elective or emergent coronar...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00