Abstract:
BACKGROUND:The meta-analysis was aimed to compare the long time (> 2 year) clinical outcomes of limus-based stents (LBS) and paclitaxel-eluting stents (PES). LBS and PES are two kinds of most common coronary artery stents in clinics. METHODS:Electronic data bases of PubMed, Cochrane, and EMBASE were searched. We included randomized controlled clinical trials (RCT) comparing LBS and PES with long time clinical outcomes. Methodological quality of eligible trials was assessed using "risk of bias" tool. The efficacy endpoints included target lesion revascularization (TLR), target vessel revascularization (TVR), and stent thrombosis (ST), and the safety endpoints included all cause death, cardiac death, and myocardial infarction (MI). Odds ratios (OR) and 95% confidence intervals (95% CI) were calculated for each endpoint. RESULTS:A total of 23 RCTs and 19,319 participants were included and analyzed in this meta-analysis. All trials were of an acceptable quality. At 2 years, LBS showed reduced risk of revascularization and ST (TLR: OR = 0.59, 95% CI 0.44-0.78; TVR: OR = 0.63, 95% CI 0.55-0.71; ST: OR = 0.55, 95% CI 0.41-0.73) and a lower rate of MI (OR = 0.67, 95% CI 0.57-0.79). Subgroup analysis showed that both everolimus-eluting stents and sirolimus-eluting stents had better clinical outcomes compared with PES. The comparisons of 3, 4 and 5 year follow-up results revealed that the clinical outcomes of PES were non-inferior to those of LBS but LBS was associated with reduced risk of MI and ST at 3 years. CONCLUSIONS:LBS is associated with better clinical outcomes at 2 years. Both LBS and PES showed similar efficacy and safety at long time period.
journal_name
Cardiol Jjournal_title
Cardiology journalauthors
Gao L,Hu X,Hou Y,Xue Qdoi
10.5603/CJ.a2014.0004subject
Has Abstractpub_date
2014-01-01 00:00:00pages
211-9issue
3issn
1897-5593pii
VM/OJS/J/34787journal_volume
21pub_type
杂志文章,meta分析,评审abstract::Patients with complete interruption of the aortic arch (IAA) very rarely reach late adulthood without having undergone surgical intervention. Only a few cases of IAA in adults have been reported in the medical literature. In this case report, we present a late diagnosis of interrupted aortic arch in a 68 year-old male...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2011.0036
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Implantable loop recorders (ILR) are a valuable tool for the investigation of unexplainedsyncopal episodes. The aim of this retrospective single center study was to identify predictive factors for pacemaker implantation in patients with unexplained syncope who underwent ILR insertion. METHODS:One hundred si...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0008
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:This study addresses the safety, feasibility, and interpretability of coronary computed tomography angiography (CCTA) in excluding significant coronary artery disease in end-stage renal disease patients on dialysis undergoing pre-renal transplant cardiac risk evaluation. METHODS:Twenty nine patients (55.5 +...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Cardiac autonomic neuropathy (CAN) is a complication of diabetes mellitus (DM) that is associated with increased mortality. Exercise-based assessment of autonomic function has identified diminished parasympathetic reactivation after exercise in type 2 DM. It is postulated herein, that this would be more prom...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2020.0064
更新日期:2020-05-07 00:00:00
abstract::QRS duration and morphology, evaluated via a standard 12-lead electrocardiogram (ECG), represent an opportunity to derive useful prognostic information regarding the risk of subsequent cardiac events or therapeutic outcomes. Prolonged QRS duration, and the presence of intraventricular conduction abnormalities, usually...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Water immersion may cause adverse cardiovascular events, including arrhythmias in patients with damaged cardiac muscle, e.g. with cardiac failure. So far, there have been rather few reports on arrhythmia induced by water training in patients with coronary artery disease (CAD). The aim of the study was to ass...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2015.0065
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Beta-catenin has been implicated in cell-cell communication in a wide variety of developmental and physiological processes. Defective Wnt signaling could result in various cardiac and vascular abnormalities. Little is known regarding Wnt/frizzled pathway in cardiomyocyte apoptosis. METHODS:In this study, th...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2016.0087
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Sudden death risk in Williams syndrome (WS) patients has been shown to be 25-100 times higher than in the general population. This study aims to detect coronary artery anomalies and myocardial perfusion defects in WS patients using noninvasive diagnostic methods. METHODS:This study features 38 patients diag...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2012.0053
更新日期:2012-01-01 00:00:00
abstract::The prevalence of diabetes mellitus (DM) is growing worldwide. Prothrombotic and proinflammatory states, in adjunct to endothelial dysfunction and metabolic disorders, such as hyperglycemia, dyslipidemia, obesity, insulin resistance, and oxidative stress, are key features of the accelerated atherosclerotic progression...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:10.5603/CJ.2013.0090
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The additional purpose for pacemaker implantation, beyond treating arrhythmias and conduction disturbances, is to improve the quality of life (QoL) of the patient. Most previous research has shown this purpose to have been achieved. However, the question as to whether all mental and physical components impro...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The meta-analysis was performed to evaluate the effect of dissection and re-entry (DR) vs. wire escalation (WE) techniques on long-term clinical outcomes in patients with chronic total occlusion (CTO) lesions undergoing percutaneous coronary intervention (PCI). METHODS:Studies were searched in electronic da...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2020.0026
更新日期:2020-02-27 00:00:00
abstract::At present there is consent that patients with acute pulmonary embolism (APE) and hemodynamic instability have poor prognosis and benefit from thrombolytic therapy or embolectomy, whereas hemodynamically stable patients without echocardiographic signs of right ventricular overload/dysfunction (RVO) have good prognosis...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Therapeutic hypothermia and targeted temperature management are considered standard of care in the management of patients following out-of-hospital cardiac arrests due to shockable rhythms to improve neurological outcomes. In those presenting out-of-hospital cardiac arrests associated with non-shockable rhyt...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:10.5603/CJ.a2017.0016
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:We aimed to prospectively assess the influence of the recommended dose, 1.0 g of polyunsaturated fatty acids (N-3 PUFA) daily, on platelet reactivity in patients with stable angina pectoris (SAP) after elective percutaneous coronary intervention (PCI). METHODS:Forty consecutive patients with SAP and success...
journal_title:Cardiology journal
pub_type: 杂志文章,随机对照试验
doi:10.5603/CJ.2013.0132
更新日期:2013-01-01 00:00:00
abstract::Diabetic ketoacidosis is a major cause of morbidity and mortality in patients with insulin dependent diabetes. Myocardial infarction is an uncommon but well-recognised precipitating cause of diabetic ketoacidosis, accounting for 1% of cases. Many diabetic patients with ketoacidosis initially present with hyperkelamia,...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate the feasibility of the use of a quadripolar left ventricular (LV) lead for cardiac resynchronization therapy and to compare its acute and mid-term outcomes with those obtained with bipolar leads. Cardiac resynchronization exhibits a high incidence of problems involvi...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2012.0087
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to compare risk predicted using available risk scores and actual outcomes in patients with left main coronary artery disease undergoing percutaneous coronary intervention with stent implantation (PCI LM). METHODS:We studied 204 patients treated with elective or emergent coronar...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Evaluating prospectively the feasibility, accuracy and reproducibility of optical flow ratio (OFR), a novel method of computational physiology based on optical coherence tomography (OCT). METHODS AND RESULTS:Sixty consecutive patients (76 vessels) underwent prospectively OCT, angiography- based quantitative...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2020.0071
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The increasing number of patients with cardiac implantable electronic devices (CIEDs) causes a rise in the absolute percentage of individuals qualifying for a transvenous lead extraction (TLE) due to infectious, vascular or lead failure related indications. As the survival time prolongs, TLE procedures more ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2013.0143
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Recent clinical studies have shown that treatment with LCZ696, a complex containing the angiotensin receptor blocker valsartan and neprilysin inhibitor sacubitril, improves the prognosis of heart failure patients with a reduced ejection fraction. This study evaluated whether LCZ696 affects left ventricular h...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0048
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:The aim of this study is to evaluate heart rate recovery (HRR) and association between coronary flow rate and HRR in patients with metabolic syndrome (MS) who had morphologically normal coronary angiogram. METHODS:Study population included 43 patients with MS and 37 control subjects without MS. All patients...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2013.0119
更新日期:2014-01-01 00:00:00
abstract::Pulmonary hypertension (PH) is a rare and devastating disease characterized by progressive increases in pulmonary arterial pressure and pulmonary vascular resistance, which eventually leads to right ventric-ular failure and death. Pulmonary arterial hypertension (PAH) (World Health Organization Group I), a subset of P...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0096
更新日期:2020-01-01 00:00:00
abstract::Dual antiplatelet therapy is currently recommended for all patients with acute coronary syndromes, independent of whether they receive pharmacological treatment or undergo percutaneous coronary intervention. Antiplatelet agents are the cornerstone of pharmacological treatment in interventional cardiology. However, the...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The aim of the study was to evaluate the role of cardiopulmonary exercise testing (CPET) parameters in assessing exercise capacity improvement after percutaneous pulmonary valve implantation (PPVI). Additionally, it aimed to determine if there are any baseline characteristics influencing that change. METHOD...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2015.0013
更新日期:2015-01-01 00:00:00
abstract::The identification of high-risk patients with hypertrophic cardiomyopathy (HC) for primary prevention of sudden cardiac death (SCD) remains a challenging issue, since major risk factors sometimes lack specificity. We report the case of a patient with HC and association of apical aneurysm and myocardial bridging who...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2012.0119
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:We aimed to assess in-hospital outcomes of percutaneous transluminal coronary angioplasty (PTCA) in elderly subjects. METHODS:A total of 1000 consecutive patients, who had all been admitted for interventional treatment of symptomatic coronary artery disease, were retrospectively analysed. RESULTS:Elderly p...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:This paper describes the clinical outcomes from a novel direct access arrhythmia monitoring service. METHODS:The study was carried out in the north of Scotland. Data was collected over a 29 month period between 18 June 2008 and 8 November 2010 from consecutive cases from two groups of patients, general prac...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2012.0010
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Intravenous hydration during percutaneous coronary intervention (PCI) significantly reduces the risk of contrast-induced nephropathy (CIN), but there are no well-defined protocols regard¬ing the optimal hydration volume (HV) required to prevent CIN following emergent PCI. Therefore, this study investigates t...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0048
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess antiplatelet effect of prasugrel in acute coronary syndrome (ACS) patients with high on-treatment platelet reactivity (HTPR) on clopidogrel, undergoing percutaneous coronary intervention (PCI). METHODS:A prospective, platelet reactivity-guided, parallel-group, open-label ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2014.0026
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Although it has been realized that restrictive mitral valve annuloplasty (MVA) may re-sult in clinically significant functional mitral stenosis (MS), it still cannot be predicted. The purpose of this study was to identify risk factors for clinically significant functional MS following restrictive MVA surgery...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0023
更新日期:2019-01-01 00:00:00