Diagnostic accuracy and reproducibility of optical flow ratio for functional evaluation of coronary stenosis in a prospective series.

Abstract:

BACKGROUND:Evaluating prospectively the feasibility, accuracy and reproducibility of optical flow ratio (OFR), a novel method of computational physiology based on optical coherence tomography (OCT). METHODS AND RESULTS:Sixty consecutive patients (76 vessels) underwent prospectively OCT, angiography- based quantitative flow ratio (QFR) and fractional flow ratio (FFR). OFR was computed offline in a central core-lab by analysts blinded to FFR. OFR was feasible in 98.7% of the lesions and showed excellent agreement with FFR (ICCa = 0.83, r = 0.83, slope = 0.80, intercept = 0.17, kappa = 0.84). The area under curve to predict an FFR ≤ 0.80 was 0.95, higher than for QFR (0.91, p = 0.115) and for minimal lumen area (0.64, p < 0.001). Diagnostic accuracy, sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio and negative likelihood ratio were 93%, 92%, 93%, 88%, 96%, 13.8, 0.1, respectively. Median time to obtain OFR was 1.07 (IQR: 0.98-1.16) min, with excellent intraobserver and interobserver reproducibility (0.97 and 0.95, respectively). Pullback speed had negligible impact on OFR, provided the same coronary segment were imaged (ICCa = 0.90, kappa = 0.697). CONCLUSIONS:The prospective computation of OFR is feasible and reproducible in a real-world series, resulting in excellent agreement with FFR, superior to other image-based methods.

journal_name

Cardiol J

journal_title

Cardiology journal

authors

Gutiérrez-Chico JL,Chen Y,Yu W,Ding D,Huang J,Huang P,Jing J,Chu M,Wu P,Tian F,Xu B,Tu S

doi

10.5603/CJ.a2020.0071

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

350-361

issue

4

issn

1897-5593

pii

VM/OJS/J/69010

journal_volume

27

pub_type

杂志文章
  • Neprilysin inhibition: A brief review of past pharmacological strategies for heart failure treatment and future directions.

    abstract::Heart failure (HF) is a manifestation of aberrant vascular responses and remains a public health concern with a worldwide prevalence of around 23 million and a 5-year mortality numerically equivalent to many cancers. Over the last two decades, mortality from HF reached a plateau with current pharmaceutical agents and ...

    journal_title:Cardiology journal

    pub_type: 杂志文章,评审

    doi:10.5603/CJ.a2016.0063

    authors: Howell EH,Cameron SJ

    更新日期:2016-01-01 00:00:00

  • Evaluation of the InterTAK Diagnostic Score in differentiating Takotsubo syndrome from acute coronary syndrome. A single center experience.

    abstract:BACKGROUND:The aim of this study was to evaluate the usefulness of a novel clinical score - the InterTAK Diagnostic Score in differentiating Takotsubo syndrome (TTS) from acute coronary syndrome (ACS). METHODS:Medical records of 40 consecutive patients with ACS and 20 patients with TTS were managed and retrospectively...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2019.0086

    authors: Samul-Jastrzębska J,Roik M,Wretowski D,Łabyk A,Ślubowska A,Bizoń A,Paczyńska M,Kurnicka K,Pruszczyk P,Ciurzyński M

    更新日期:2019-09-06 00:00:00

  • Prevalence and prognostic relevance of myocardial inflammation and cardiotropic viruses in non-ischemic dilated cardiomyopathy.

    abstract:BACKGROUND:Non-ischemic dilated cardiomyopathy (DCM) is a heterogeneous disease with a spectrum of etiological factors. However, subsets of the disease are not well-characterized with respect to these factors. The aim of this study was to evaluate the prevalence of myocardial inflammation and cardiotropic viruses in DC...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2020.0088

    authors: Kažukauskienė I,Baltrūnienė V,Jakubauskas A,Žurauskas E,Maneikienė VV,Daunoravičius D,Čelutkienė J,Ručinskas K,Grabauskienė V

    更新日期:2020-06-22 00:00:00

  • Evaluation of exercise capacity with cardiopulmonary exercise test and B-type natriuretic peptide in adults with congenital heart disease.

    abstract:BACKGROUND:Adult patients with congenital heart disease (CHD) usually find their exercise capacity satisfactory. However, objective evaluation is important for diagnostic and prognostic purposes. The aim of this study was to evaluate exercise capacity using cardiopulmonary exercise tests and measurement of serum B-type...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Trojnarska O,Gwizdała A,Katarzyński S,Katarzyńska A,Szyszka A,Lanocha M,Grajek S,Kramer L

    更新日期:2009-01-01 00:00:00

  • Mechanical efficiency of high versus moderate intensity aerobic exercise in coronary heart disease patients: A randomized clinical trial.

    abstract:BACKGROUND:Mechanical efficiency (ME) refers to the ability of an individual to transfer energy consumed by external work. A decreased ME, could represent an increased energy cost during exercise and may, therefore, be limited in terms of physical activity. This study aimed to compare the influence of two different exe...

    journal_title:Cardiology journal

    pub_type: 杂志文章,随机对照试验

    doi:10.5603/CJ.a2018.0052

    authors: Villelabeitia-Jaureguizar K,Vicente-Campos D,Berenguel Senen A,Hernández Jiménez V,Ruiz Bautista L,Barrios Garrido-Lestache ME,López Chicharro J

    更新日期:2019-01-01 00:00:00

  • Importance of cardiac biomarkers in risk stratification in acute pulmonary embolism.

    abstract::At present there is consent that patients with acute pulmonary embolism (APE) and hemodynamic instability have poor prognosis and benefit from thrombolytic therapy or embolectomy, whereas hemodynamically stable patients without echocardiographic signs of right ventricular overload/dysfunction (RVO) have good prognosis...

    journal_title:Cardiology journal

    pub_type: 杂志文章,评审

    doi:

    authors: Mikulewicz M,Lewczuk J

    更新日期:2008-01-01 00:00:00

  • Catheter entrapment due to severe radial artery spasm during transradial approach.

    abstract:BACKGROUND:Catheter entrapment due to severe radial artery spasm (RAS) during transradial coronary catheterization has been rarely reported and its management is not precisely defined. The aim of this study was to determine the incidence, predictors and management of catheter entrapment due to severe RAS. METHODS:A to...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2016.0022

    authors: Zencirci E,Değirmencioğlu A

    更新日期:2016-01-01 00:00:00

  • Pulmonary arterial hypertension in the elderly: Clinical perspectives.

    abstract::Pulmonary hypertension (PH) is a rare and devastating disease characterized by progressive increases in pulmonary arterial pressure and pulmonary vascular resistance, which eventually leads to right ventric-ular failure and death. Pulmonary arterial hypertension (PAH) (World Health Organization Group I), a subset of P...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2018.0096

    authors: Rothbard N,Agrawal A,Fischer C,Talwar A,Sahni S

    更新日期:2020-01-01 00:00:00

  • The treatment of acute myocardial infarction due to the occlusion of the left main coronary disease.

    abstract::Acute myocardial infarction (AMI) due to the occlusion of the left main coronary artery (LMCA) is a rare but serious condition in the era of percutaneus coronary intervention (PCI). Even more rare is AMI involved with both LMCA and its branches like trifurcartion or bifurcation: this is challenging for interventional ...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Can MM,Tanboga H,Karabay CY,Güler A,Akgun T,Turkyilmaz E,Ozveren O,Mutlu B

    更新日期:2011-01-01 00:00:00

  • Quality of visualization of coronary venous system in 64-slice computed tomography.

    abstract:BACKGROUND:Multi-slice computed tomography (MSCT) can be used to visualize the anatomy of the coronary venous system (CVS). A pre-procedural evaluation of target veins is a very important element of cardiac resynchronization. Thus, the quality of visualization of the CVS is of great importance. The aim of this study wa...

    journal_title:Cardiology journal

    pub_type: 临床试验,杂志文章

    doi:

    authors: Młynarska A,Młynarski R,Kargul W,Sosnowski M

    更新日期:2011-01-01 00:00:00

  • Relationship between R-R interval variation and left ventricular function in sinus rhythm and atrial fibrillation as estimated by means of heart rate variability fraction.

    abstract:BACKGROUND:Reduced heart rate variability (HRV) is associated with a poor outcome in patients with sinus rhythm (SR) or atrial fibrillation (AF). However, cut-off points for HRV measures differ between SR and AF. We hypothesized that a global index of 24-hour HRV based on evaluation of scatterplot would describe HRV ir...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/cj.2011.0010

    authors: Sosnowski M,Korzeniowska B,Macfarlane PW,Tendera M

    更新日期:2011-01-01 00:00:00

  • Risk factor paradox: No prognostic impact of arterial hypertension and smoking in patients with ventricular tachyarrhythmias.

    abstract:BACKGROUND:Data regarding the outcome of patients with ventricular tachyarrhythmias related to arterial hypertension (AHT) and smoking is limited. The study sought to assess the prognostic impact of AHT and smoking on survival in patients presenting with ventricular tachyarrhythmias. METHODS:All consecutive patients s...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2018.0158

    authors: Weidner K,Behnes M,Rusnak J,Taton G,Schupp T,Reiser L,Bollow A,Reichelt T,Ellguth D,Engelke N,Kuche P,Hoppner J,El-Battrawy I,Lang S,Nienaber CA,Mashayekhi K,Ferdinand D,Weiß C,Borggrefe M,Akin I

    更新日期:2020-01-01 00:00:00

  • Percutaneous coronary angioplasty in elderly patients: Assessment of in-hospital outcomes.

    abstract:BACKGROUND:We aimed to assess in-hospital outcomes of percutaneous transluminal coronary angioplasty (PTCA) in elderly subjects. METHODS:A total of 1000 consecutive patients, who had all been admitted for interventional treatment of symptomatic coronary artery disease, were retrospectively analysed. RESULTS:Elderly p...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Sukiennik A,Król A,Jachalska A,Koziński M,Fabiszak T,Kubica A,Radomski M,Demidowicz K,Bogdan M,Raczak G,Sukiennik T,Zabielska E,Dobosiewicz R,Rychter M,Jabłoński M,Białoszyński T,Chojnicki M,Grześk G,Kubica J

    更新日期:2007-01-01 00:00:00

  • Successful coronary stent retrieval from the renal artery.

    abstract::Coronary stent loss and its migration is one of complications of percutaneous coronary interventions (PCI). We present a case of successful retrieval of a coronary stent which moved initially to the left renal artery. Subsequently the stent was lost again and migrated to the left deep femoral artery, while an attempt ...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Juszkat R,Dziarmaga M,Zabicki B,Bychowiec B

    更新日期:2007-01-01 00:00:00

  • N-3 polyunsaturated fatty acids do not influence the efficacy of dual antiplatelet therapy in stable angina pectoris patients after percutaneous coronary intervention.

    abstract:BACKGROUND:We aimed to prospectively assess the influence of the recommended dose, 1.0 g of polyunsaturated fatty acids (N-3 PUFA) daily, on platelet reactivity in patients with stable angina pectoris (SAP) after elective percutaneous coronary intervention (PCI). METHODS:Forty consecutive patients with SAP and success...

    journal_title:Cardiology journal

    pub_type: 杂志文章,随机对照试验

    doi:10.5603/CJ.2013.0132

    authors: Mizia-Stec K,Mizia M,Haberka M,Lasota B,Gieszczyk-Strózik K,Chmiel A,Najda J,Gąsior Z,Kyrcz-Krzemień S

    更新日期:2013-01-01 00:00:00

  • Rationale of decreasing low-density lipoprotein cholesterol below 70 mg/dL in patients with coronary artery disease: A retrospective virtual histology-intravascular ultrasound study.

    abstract:BACKGROUND:The associations between statin and coronary plaque compositional changes were re-ported according to the use of high dose or not. An evaluation of the impact of low-density lipoprotein cholesterol (LDL-C) < 70 mg/dL by using real world dosages of statin on coronary plaque composition was undertaken. METHOD...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2018.0002

    authors: Seo YH,Seo DJ,Song IG,Kim KH,Kwon TG,Bae JH

    更新日期:2018-01-01 00:00:00

  • Evaluation of the prognostic value of electrocardiography parameters and heart rhythm in patients with pulmonary hypertension.

    abstract:BACKGROUND:Several studies have analyzed arrhythmias in patients with pulmonary hypertension (PH) and increased P-wave duration was identified as a risk factor for development of atrial fibrillation (AF). METHODS:We retrospectively analyzed the incidence of arrhythmias in patients with an initial diagnosis of PH durin...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2016.0044

    authors: Bandorski D,Bogossian H,Ecke A,Wiedenroth C,Gruenig E,Benjamin N,Arlt M,Seeger W,Mayer E,Ghofrani A,Hoeltgen R,Gall H

    更新日期:2016-01-01 00:00:00

  • Association between plasma concentration of tolvaptan and urine volume in acute decompensated heart failure patients with fluid overload.

    abstract:BACKGROUND:Tolvaptan (TLV) is a useful diuretic for acute decompensated heart failure (ADHF) with fluid overload, but its clinical response varies between patients. The aim of this study is to investigate whether plasma TLV concentrations correlate with the urine volume. METHODS:ADHF inpatients with evidence of fluid ...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2016.0055

    authors: Kato M,Tohyama K,Ohya T,Hiro T,Hirayama A

    更新日期:2016-01-01 00:00:00

  • Time-to-effect guided pulmonary vein isolation utilizing the third-generation versus second generation cryoballoon: One year clinical success.

    abstract:BACKGROUND:The second-generation cryoballoon (CB2) provides effective and durable pulmonary vein isolation (PVI) associated with encouraging and reproducible clinical outcome data. The latest- -generation cryoballoon (CB3) incorporates a 40% shorter distal tip, thus allowing for an increased rate of PVI real-time signa...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2018.0056

    authors: Heeger CH,Schuette C,Seitelberger V,Wissner E,Rillig A,Mathew S,Reissmann B,Lemes C,Maurer T,Fink T,Inaba O,Hashiguchi N,Santoro F,Ouyang F,Kuck KH,Metzner A

    更新日期:2019-01-01 00:00:00

  • Renin-angiotensin system inhibition is associated with reduced risk of left atrial appendage thrombosis formation in patients with atrial fibrillation.

    abstract:BACKGROUND:Inhibition of the renin-angiotensin axis can reduce the likelihood of atrial fibrillation (AF). However, the effects of angiotensin-converting-enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) on thrombogenicity in AF remain incompletely elucidated. Thisretrospective case-control study was...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2017.0112

    authors: Suo Y,Zhang Y,Wang Y,Yuan M,Kariyawasam S,Tse G,Liu T,Fu H,Li G

    更新日期:2018-01-01 00:00:00

  • The ventricular assist device: a bridge to ventricular recovery, a bridge to heart transplantation or destination therapy?

    abstract::Despite advances in pharmacological treatments aimed at a neurohormonal blockade for heart failure, there is still a growing number of patients with advanced symptoms who suffer significant morbidity and mortality. At present the most effective cure for end-stage congestive heart failure is cardiac transplantation. Th...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Bielecka A,Wierzbicka M,Goch J

    更新日期:2007-01-01 00:00:00

  • Paravalvular leak after transcatheter aortic valve implantation (TAVI): Short-term results. Data from Polish national POL-TAVI registry.

    abstract:BACKGROUND:The authors analyzed data from Polish national POL-TAVI registry in terms of paravalvular leak (PVL) occurrence after transcatheter aortic valve implantation (TAVI) and its impact on clinical outcomes. METHODS:A total of 331 patients with severe aortic stenosis underwent TAVI (Edwards Sapien, n = 141; CoreV...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2015.0071

    authors: Kleczyński P,Zasada W,Bagieński M,Rzeszutko Ł,Sorysz D,Sobczyński R,Trębacz J,Kapelak B,Zembala M,Dudek D

    更新日期:2016-01-01 00:00:00

  • Left atrial mechanical function and stiffness in patients with atrial septal aneurysm: a speckle tracking study.

    abstract:BACKGROUND:Atrial septal aneurysm (ASA) is a risk factor for arterial embolism. Atrial dysfunction and atrial arrhythmia, such as atrial fibrillation, might represent a mechanism for arterial embolism in such patients. Speckle tracking echocardiography (STE) is a novel and promising tool for detecting early changes in ...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2015.0033

    authors: Demir M,Aktaş İ,Çamci S

    更新日期:2015-01-01 00:00:00

  • Is there a beneficial effect difference between age, gender, and different cardiac pathology groups of exercise training at ventilatory threshold in cardiac patients?

    abstract:BACKGROUND:Research on cardiac rehabilitation has raised interesting methods and effects without however establishing the share of the profits according to age, sex and cardiac pathology. Yet today, this disease with various pathologies strikes people of all ages and both sexes, and the recommended rehabilitation exerc...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/cj.2011.0026

    authors: Temfemo A,Chlif M,Mandengue SH,Lelard T,Choquet D,Ahmaidi S

    更新日期:2011-01-01 00:00:00

  • Improved arterial stiffness in mitral stenosis after successful percutaneous balloon valvuloplasty.

    abstract:BACKGROUND:Rheumatic mitral stenosis (MS) is still a common disease in developing countries with high morbidity and mortality rates. The purpose of the study was to evaluate arterial stiffness in severe MS before and after percutaneous mitral balloon valvuloplasty (PMBV). METHODS:Thirty patients with MS in sinus rhyth...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/cj.2012.0109

    authors: Ozdogru I,Celik A,Dogan A,Orscelik O,Sahin O,Elcik D,Saka T,Topsakal R,Oguzhan A

    更新日期:2012-01-01 00:00:00

  • Changes in the mental and physical components of the quality of life for patients six months after pacemaker implantation.

    abstract:BACKGROUND:The additional purpose for pacemaker implantation, beyond treating arrhythmias and conduction disturbances, is to improve the quality of life (QoL) of the patient. Most previous research has shown this purpose to have been achieved. However, the question as to whether all mental and physical components impro...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Młynarski R,Włodyka A,Kargul W

    更新日期:2009-01-01 00:00:00

  • The comparison of contrast echocardiography and tissue Doppler imaging for evaluation of reperfused myocardium in patients with acute anterior myocardial infarction.

    abstract:BACKGROUND:Prediction of functional myocardial recovery post acute myocardial infarction should be based not only on flow patency of the infarct related artery (IRA) but also on the quality of microcirculation in at-risk segments. Myocardial blush grade (MBG) is a method of perfusion assessment which has an established...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Streb W,Duszańska A,Stabryła-Deska J,Pluta S,Swierad M,Was T,Kalarus Z,Kukulski T

    更新日期:2008-01-01 00:00:00

  • Implantable loop recorders in patients with unexplained syncope: Clinical predictors of pacemaker implantation.

    abstract:BACKGROUND:Implantable loop recorders (ILR) are a valuable tool for the investigation of unexplainedsyncopal episodes. The aim of this retrospective single center study was to identify predictive factors for pacemaker implantation in patients with unexplained syncope who underwent ILR insertion. METHODS:One hundred si...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2018.0008

    authors: Huemer M,Becker AK,Wutzler A,Attanasio P,Parwani AS,Lacour P,Boldt LH,Pieske B,Haverkamp W,Blaschke F

    更新日期:2019-01-01 00:00:00

  • Evaluation of left ventricular systolic function with pulsed wave tissue Doppler in rheumatic mitral stenosis.

    abstract:BACKGROUND:Mitral stenosis (MS) is still the most common complication of acute rheumatic fever in Turkey. Rheumatic carditis affects not only cardiac valves but also myocardium. In this study, we aimed to evaluate the subclinical left ventricular (LV) systolic dysfunction and contraction of short and long axial circumf...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:10.5603/CJ.a2013.0058

    authors: Guven S,Sen T,Tufekcioglu O,Gucuk E,Uygur B,Kahraman E

    更新日期:2014-01-01 00:00:00

  • Myocardial infarction in a low risk patient with hereditary hemorrhagic telangiectasia.

    abstract::We describe the case of a 57 year-old woman with NSTE ACS, a history of recurrent and prolonged epistaxis, and low prior cardiovascular risk. Additional findings revealed anemia and an aneurysm in her central nervous system. During her hospital stay, hereditary hemorrhagic telangiectasia (HHT) was diagnosed. After app...

    journal_title:Cardiology journal

    pub_type: 杂志文章

    doi:

    authors: Janion M,Brzyzkiewicz H,Siuda M,Domagała S,Karliński M

    更新日期:2010-01-01 00:00:00