Abstract:
:The prevalence of diabetes mellitus (DM) is growing worldwide. Prothrombotic and proinflammatory states, in adjunct to endothelial dysfunction and metabolic disorders, such as hyperglycemia, dyslipidemia, obesity, insulin resistance, and oxidative stress, are key features of the accelerated atherosclerotic progression observed in patients with DM. Moreover, drug-eluting stents (DES) thrombosis rate was higher in DM than in non-DM patients and DM itself was identifi ed as an independent predictor of stent thrombosis, particularly due to the impaired response to dual antiplatelet therapy. The accumulating data even before the FREEDOM trial provided strong evidence that in patients with DM and complex coronary artery disease, coronary artery bypass grafting (CABG) was superior to percutaneous coronary intervention (PCI) which was based on the first-generation DES. The FREEDOM trial enrolled 1900 patients with DM and multivessel coronary artery disease treated with CABG surgery or PCI with the first-generation DES. The patients were followed for a median 3.8 years; CABG was superior to PCI as it significantly reduced rates of death and myocardial infarction (MI), with a higher rate of stroke. The benefit of CABG was driven by differences in rates of both MI (p < 0.001) and death from any cause (p = 0.049). Following the FREEDOM results, patients with DM ought to be informed before coronary angiography about the potential survival benefit from CABG for the treatment of a complex disease. However, it should be noticed that the second generation DES were associated with better outcomes compared to the first-generation DES. New stent designs are continually being developed, with the aim of further improving the clinical effi cacy and the safety profile of these devices. Therefore, although the results of the FREEDOM trial clearly demonstrated that CABG was superior to PCI in DM, a comparative analysis of the new incoming stents warrants further investigation.
journal_name
Cardiol Jjournal_title
Cardiology journalauthors
Tenenbaum A,Fisman EZdoi
10.5603/CJ.2013.0090subject
Has Abstractpub_date
2013-01-01 00:00:00pages
331-6issue
4issn
1897-5593pii
VM/OJS/J/33831journal_volume
20pub_type
杂志文章,评审abstract:BACKGROUND:In those without symptoms of coronary artery disease (CAD), the incidence of coronary events is still high. The aim of this study was to evaluate whether flow mediated dilatation (FMD) is a useful tool in identifying those with CAD in who are under 45 years of age. METHODS AND RESULTS:Seventy five men below...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate the feasibility of the use of a quadripolar left ventricular (LV) lead for cardiac resynchronization therapy and to compare its acute and mid-term outcomes with those obtained with bipolar leads. Cardiac resynchronization exhibits a high incidence of problems involvi...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2012.0087
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Data regarding the outcome of patients with ventricular tachyarrhythmias related to arterial hypertension (AHT) and smoking is limited. The study sought to assess the prognostic impact of AHT and smoking on survival in patients presenting with ventricular tachyarrhythmias. METHODS:All consecutive patients s...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0158
更新日期:2020-01-01 00:00:00
abstract::Questions have been raised on the clinical value of the metabolic syndrome (MS). The negative opinion regarding MS is anchored basically on a separate analysis of 4 conditions: obesity, dyslipidemia, hypertension and glucose intolerance. The common denominator of these 4 sets of arguments is that they represent an utt...
journal_title:Cardiology journal
pub_type: 杂志文章,meta分析,评审
doi:10.5603/CJ.a2013.0054
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Inhibition of the renin-angiotensin axis can reduce the likelihood of atrial fibrillation (AF). However, the effects of angiotensin-converting-enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) on thrombogenicity in AF remain incompletely elucidated. Thisretrospective case-control study was...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0112
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Aspirin remains the mainstay of anti-platelet therapy in cardiac patients. However, if a patient is allergic to aspirin and dual anti-platelet therapy is indicated - such as with percutaneous coronary intervention (PCI), then there is no clear guidance. One possibility is aspirin desensitization. A variety o...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2013.0025
更新日期:2013-01-01 00:00:00
abstract::Diabetic ketoacidosis is a major cause of morbidity and mortality in patients with insulin dependent diabetes. Myocardial infarction is an uncommon but well-recognised precipitating cause of diabetic ketoacidosis, accounting for 1% of cases. Many diabetic patients with ketoacidosis initially present with hyperkelamia,...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Water immersion may cause adverse cardiovascular events, including arrhythmias in patients with damaged cardiac muscle, e.g. with cardiac failure. So far, there have been rather few reports on arrhythmia induced by water training in patients with coronary artery disease (CAD). The aim of the study was to ass...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2015.0065
更新日期:2016-01-01 00:00:00
abstract::Cardiac resynchronization therapy (CRT) is electrical resynchronization of the ventricles. Bachmann's bundle (BB) pacing is considered to be electrical resynchronization of the atria. Atrial fibrillation (AF) and congestive heart failure (HF) often coexist in the same patient. A 69 year-old man who underwent CRT combi...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Distortion of the terminal portion of the QRS in the initial electrocardiogram (ECG) is a strong predictor of adverse outcome in myocardial infarction. Our purpose is to assess the relationship of distortion of QRS and other ECG characteristics with older age. METHODS AND RESULTS:We analysed 634 consecutive...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Vasovagal syncope (VVS) is a common symptom with empirical therapy and high recurrence rate. Our goal was to determine whether the pattern of presyncopal prodromal symptoms can predict the recurrence probability of vasovagal syncope. METHODS:Seventy-nine consecutive patients (male/female: 53/26) with histor...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Concomitant thyroid and heart disease are frequently encountered in clinical practice. There are many studies evaluating thyroid function in acute and critical conditions. Information on thyroid dysfunction in ST-segment elevation myocardial infarction (STEMI) is limited; its correlation with short and long-...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2013.0108
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Mitral stenosis (MS) is still the most common complication of acute rheumatic fever in Turkey. Rheumatic carditis affects not only cardiac valves but also myocardium. In this study, we aimed to evaluate the subclinical left ventricular (LV) systolic dysfunction and contraction of short and long axial circumf...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2013.0058
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Patients with supraventricular tachycardia (SVT) and patients with coronary artery disease (CAD) often present with similar symptoms (chest pain, shortness of breath), similar electrocar¬diographic changes and elevated high-sensitivity troponin (Tn). It is not clear whether troponin reflects critical CAD or ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0058
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Red cell distribution width (RDW) in acute heart failure (AHF) is accepted as a prognostic indicator with unclear pathophysiological ties. The aim of this study was to evaluate the prognostic value of RDW in AHF patients in relation to clinical and echocardiographic data. METHODS:170 patients with AHF were ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0103
更新日期:2020-01-01 00:00:00
abstract::Upstream therapy is the promising issue in the treatment of atrial fibrillation (AF) especially in patients with arterial hypertension and heart failure. The possible beneficial effects of renin-angiotensin-aldosterone system blockade with ACE-inhibitors and angiotensin receptor antagonists in AF prevention have been ...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:10.5603/cj.2012.0043
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Sudden death risk in Williams syndrome (WS) patients has been shown to be 25-100 times higher than in the general population. This study aims to detect coronary artery anomalies and myocardial perfusion defects in WS patients using noninvasive diagnostic methods. METHODS:This study features 38 patients diag...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2012.0053
更新日期:2012-01-01 00:00:00
abstract::A 25 year-old female with a history of Caesarian section ten weeks ago presented with symptoms suggestive of pulmonary embolism. Transthoracic echocardiography revealed a free-floating large thrombus traversing the right atrial cavity. Transesophageal echocardiography confirmed the presence of an unattached thrombus t...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:The highest priority in preventive cardiology was given to patients with established coronary artery disease (CAD). The aim of the study was to assess the implementation of guidelines for secondary prevention in everyday clinical practice by evaluating control of the main risk factors and the cardioprotectiv...
journal_title:Cardiology journal
pub_type: 杂志文章,多中心研究
doi:10.5603/CJ.a2014.0066
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Coronary arteriography is still widely accepted as a gold standard for the diagnosis of coronary artery disease (CAD), despite emerging methods such as multi-slice computed tomography. None of the presently available non-invasive diagnostic tests is perfect. The aim of the article was to make a comparison of...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Objective of this study was to make an assessment of standard functional and defor-mation parameters (strain) in patients after transcatheter aortic valve replacement (TAVR) by cardiac magnetic resonance imaging (CMR) and the evaluation of their prognostic impact. METHODS:Patients undergoing TAVR received C...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0121
更新日期:2018-01-01 00:00:00
abstract::Patients with complete interruption of the aortic arch (IAA) very rarely reach late adulthood without having undergone surgical intervention. Only a few cases of IAA in adults have been reported in the medical literature. In this case report, we present a late diagnosis of interrupted aortic arch in a 68 year-old male...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2011.0036
更新日期:2011-01-01 00:00:00
abstract::Pulmonary hypertension (PH) is a rare and devastating disease characterized by progressive increases in pulmonary arterial pressure and pulmonary vascular resistance, which eventually leads to right ventric-ular failure and death. Pulmonary arterial hypertension (PAH) (World Health Organization Group I), a subset of P...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0096
更新日期:2020-01-01 00:00:00
abstract::Present day 24-h Holter monitors have been shown to miss many arrhythmias that may occur infrequently or under specific circumstances. The advancement in electronic and adhesive technologies have enabled the development of first generation wearable long-term 14-day patch ECG monitors that attach directly to the skin a...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:10.5603/cj.2012.0039
更新日期:2012-01-01 00:00:00
abstract::We present a case of patent ductus arteriosus with severe pulmonary hypertension with the rare association of absent right pulmonary artery. ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2013.0018
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Several studies have analyzed arrhythmias in patients with pulmonary hypertension (PH) and increased P-wave duration was identified as a risk factor for development of atrial fibrillation (AF). METHODS:We retrospectively analyzed the incidence of arrhythmias in patients with an initial diagnosis of PH durin...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2016.0044
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:The relationship between admission triglyceride (TG) levels and long-term outcomes has not been established in patients with acute coronary syndrome. We tested the hypothesis that patients who develop non-ST segment elevation myocardial infarction (NSTEMI) despite low TG have a worse cardiovascular outcome i...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Coronary sinus (CS) has been shown to be larger in patients with atrioventricular nodal reentrant tachycardia (AVNRT). We sought to determine if echocardiographically measured CS diameter can help identify the mechanism of tachycardia in patients with narrow complex tachycardia without preexcitation before t...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2013.0088
更新日期:2014-01-01 00:00:00
abstract::This image showed tension pneumopericardium caused by removing the pericardiocentesis catheter, which was inserted to drain malignant pericardial effusion. Tension pneumopericardium is a rare and potentially fatal event. Mortality from tension pneumopericardium can be as high as 50%. Therefore, it is important to susp...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Beta-catenin has been implicated in cell-cell communication in a wide variety of developmental and physiological processes. Defective Wnt signaling could result in various cardiac and vascular abnormalities. Little is known regarding Wnt/frizzled pathway in cardiomyocyte apoptosis. METHODS:In this study, th...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2016.0087
更新日期:2017-01-01 00:00:00