Abstract:
BACKGROUND:Aspirin remains the mainstay of anti-platelet therapy in cardiac patients. However, if a patient is allergic to aspirin and dual anti-platelet therapy is indicated - such as with percutaneous coronary intervention (PCI), then there is no clear guidance. One possibility is aspirin desensitization. A variety of protocols exist for the rapid desensitization of patients with aspirin allergy. The aim of this survey was to assess current knowledge and practice regarding aspirin desensitization in the UK. METHODS AND RESULTS:We conducted a UK wide survey of all UK 116 PCI centers and obtained complete responses from 40 (35.4%) centers. Of these, just 7 (17.5%) centers had previously desensitised patients; 29 (87.9%) centers suggested a lack of a local protocol prevented them from desensitizing, with 10 (30.3%) unsure of how to conduct desensitization. Only 5 (12.5%) centers had a local policy for aspirin desensitization although 25 (64.1%) units had a clinical strategy for dealing with aspirin allergy; the majority (72%) giving higher doses of thienopyridine class drugs. CONCLUSIONS:In the UK, there appears to be no consistent approach to patients with aspirin allergy. Patients undergoing PCI benefit from dual anti-platelet therapy (including aspirin), and aspirin desensitization in those with known allergy may facilitate this. Sustained effort should be placed on encouraging UK centers to use desensitization as a treatment modality prior to PCI rather than avoiding aspirin altogether.
journal_name
Cardiol Jjournal_title
Cardiology journalauthors
Chapman AR,Rushworth GF,Leslie SJdoi
10.5603/CJ.2013.0025subject
Has Abstractpub_date
2013-01-01 00:00:00pages
134-8issue
2issn
1897-5593pii
VM/OJS/J/33963journal_volume
20pub_type
杂志文章abstract:BACKGROUND:Multi-slice computed tomography (MSCT) can be used to visualize the anatomy of the coronary venous system (CVS). A pre-procedural evaluation of target veins is a very important element of cardiac resynchronization. Thus, the quality of visualization of the CVS is of great importance. The aim of this study wa...
journal_title:Cardiology journal
pub_type: 临床试验,杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Cardiac autonomic neuropathy (CAN) is a complication of diabetes mellitus (DM) that is associated with increased mortality. Exercise-based assessment of autonomic function has identified diminished parasympathetic reactivation after exercise in type 2 DM. It is postulated herein, that this would be more prom...
journal_title:Cardiology journal
pub_type: 杂志文章
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2013.0088
更新日期:2014-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章,多中心研究
doi:10.5603/CJ.a2016.0003
更新日期:2016-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0002
更新日期:2018-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2014.0100
更新日期:2015-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章,meta分析,评审
doi:10.5603/CJ.a2014.0004
更新日期:2014-01-01 00:00:00
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pub_type: 杂志文章
doi:10.5603/CJ.a2017.0024
更新日期:2017-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The presence of psoriasis is currently considered by the European Society of Cardiology cardiovascular prevention guidelines of 2016 as one possible cardiovascular risk factor. Patients with psoriasis and concomitant coronary artery disease treated by means of percutaneous coronary interven-tion (PCI) are a ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0076
更新日期:2020-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2011.0010
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Evaluating prospectively the feasibility, accuracy and reproducibility of optical flow ratio (OFR), a novel method of computational physiology based on optical coherence tomography (OCT). METHODS AND RESULTS:Sixty consecutive patients (76 vessels) underwent prospectively OCT, angiography- based quantitative...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2020.0071
更新日期:2020-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0008
更新日期:2019-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Coronary arteriography is still widely accepted as a gold standard for the diagnosis of coronary artery disease (CAD), despite emerging methods such as multi-slice computed tomography. None of the presently available non-invasive diagnostic tests is perfect. The aim of the article was to make a comparison of...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.5603/CJ.a2017.0016
更新日期:2017-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::The prevalence of diabetes mellitus (DM) is growing worldwide. Prothrombotic and proinflammatory states, in adjunct to endothelial dysfunction and metabolic disorders, such as hyperglycemia, dyslipidemia, obesity, insulin resistance, and oxidative stress, are key features of the accelerated atherosclerotic progression...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
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更新日期:2013-01-01 00:00:00
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pub_type: 杂志文章
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2016.0087
更新日期:2017-01-01 00:00:00
abstract::Pulmonary hypertension (PH) is a rare and devastating disease characterized by progressive increases in pulmonary arterial pressure and pulmonary vascular resistance, which eventually leads to right ventric-ular failure and death. Pulmonary arterial hypertension (PAH) (World Health Organization Group I), a subset of P...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0096
更新日期:2020-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0048
更新日期:2017-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2020.0026
更新日期:2020-02-27 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:The effects of left ventricular (LV) diastolic function are well known in cardiac surgery, but unclear in transcatheter aortic valve implantation (TAVI). The objective of this study was to exam- ine the association of preoperative LV diastolic function with medium to long-term outcomes of TAVI. METHODS:Eigh...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0005
更新日期:2019-01-01 00:00:00