Abstract:
BACKGROUND:The authors analyzed data from Polish national POL-TAVI registry in terms of paravalvular leak (PVL) occurrence after transcatheter aortic valve implantation (TAVI) and its impact on clinical outcomes. METHODS:A total of 331 patients with severe aortic stenosis underwent TAVI (Edwards Sapien, n = 141; CoreValve, n = 190). The grade of PVL and survival rate were assessed at6-month follow-up. RESULTS:One hundred and eighty-one (54.7%) patients developed mild PVL, and 22 (6.6%) - moderate PVL after TAVI. No severe PVLs were observed. Occurrence of moderate PVL was device dependent and more frequent in the CoreValve group (p = 0.02). Larger CoreValve device used correlated with the grade of PVL (Spearman: r = 0.19; p = 0.01), but for Edwards Sapien devices this correlation was inverted (Spearman: r = -0.62; p = 0.01). Six-month mortality rate was not significant between patients with no or mild PVL compared to those with moderate PVL (p = 0.12). CONCLUSIONS:The PVL occurrence remains a frequent problem after TAVI and is device de-pendent, more common with Edwards 23 mm valve and 31 mm CoreValve prosthesis.
journal_name
Cardiol Jjournal_title
Cardiology journalauthors
Kleczyński P,Zasada W,Bagieński M,Rzeszutko Ł,Sorysz D,Sobczyński R,Trębacz J,Kapelak B,Zembala M,Dudek Ddoi
10.5603/CJ.a2015.0071subject
Has Abstractpub_date
2016-01-01 00:00:00pages
163-8issue
2issn
1897-5593pii
VM/OJS/J/43086journal_volume
23pub_type
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