Abstract:
BACKGROUND:Recent reports suggest that torasemide might be more beneficial than furosemide in patients with symptomatic heart failure (HF). The aim was to compare the effects of torasemide and furosemide on clinical outcomes in HF patients. METHODS:This study pilot consisted of data from the ongoing multicenter, randomized, unblinded endpoint phase IV TORNADO (NCT01942109) study. HF patients in New York Heart Association (NYHA) II-IV class with a stable dose of furosemide were randomized to treatment with equipotential dose of torasemide (4:1) or continuation of unchanged dose of furosemide. On enrollment and control visit (3 months after enrollment) clinical examination, 6-minute walk test (6MWT) and assessment of fluid retention by ZOE Fluid Status Monitor were performed. The primary endpoint was a composite of improvement of NYHA class, improvement of at least 50 m during 6MWT and decrease in fluid retention of at least 0.5 W after 3-months follow-up. RESULTS:The study group included 40 patients (median age 66 years; 77.5% male). During follow-up 7 patients were hospitalized for HF worsening (3 in torasemide and 4 in furosemide-treated patients). The primary endpoint reached 15 (94%) and 14 (58%) patients on torasemide and furosemide, respectively (p = 0.03). CONCLUSIONS:In HF patients treated with torasemide fluid overload and symptoms improved more than in the furosemide group. This positive effect occurred already within 3-month observation.
journal_name
Cardiol Jjournal_title
Cardiology journalauthors
Balsam P,Ozierański K,Marchel M,Gawałko M,Niedziela Ł,Tymińska A,Sieradzki B,Sieradzki M,Fojt A,Bakuła E,Główczyńska R,Peller M,Markulis M,Bednarski J,Kowalik R,Cacko A,Niewiński G,Filipiak KJ,Opolski G,Grabowski Mdoi
10.5603/CJ.a2019.0114subject
Has Abstractpub_date
2019-01-01 00:00:00pages
661-668issue
6issn
1897-5593pii
VM/OJS/J/65083journal_volume
26pub_type
杂志文章,多中心研究,随机对照试验abstract:BACKGROUND:Whereas coronary artery ectasia (CAE) is a rare abnormality of the coronary arteries, co-existent coronary artery disease (CAD) is commonly seen in CAE patients. Since a causative relationship has been shown to exist between oxidative stress and CAD, we sought to determine whether any relationship exists bet...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract::Due to its constantly growing incidence, obesity is an increasingly serious social and medical problem. Available data on the use of novel oral anticoagulants in morbidly obese and obese patients are very limited. However, we tried to summarize the available knowledge on the use of anticoagulants in this subpopulation...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:10.5603/CJ.a2015.0054
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Data regarding the outcome of patients with ventricular tachyarrhythmias related to arterial hypertension (AHT) and smoking is limited. The study sought to assess the prognostic impact of AHT and smoking on survival in patients presenting with ventricular tachyarrhythmias. METHODS:All consecutive patients s...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0158
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The aim of the study was to compare the effects of 2 strategies of antiplatelet treatment (i.e., 150 mg ASA vs. 75 mg clpoidogrel) on plasma level of inflammatory markers in type 2 diabetes mellitus (T2DM) patients with high platelet reactivity (HPR). METHODS:Study cohort consisted of 304 T2DM patients on c...
journal_title:Cardiology journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.5603/CJ.2013.0045
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Subcostal planes allow demonstration of the entire right ventricular cavity and are frequently used in patients with congenital heart disease; however, their clinical utility in the evaluation of systemic right ventricular function after atrial switch procedure for complete transposition has never been verif...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:We aimed to assess in-hospital outcomes of percutaneous transluminal coronary angioplasty (PTCA) in elderly subjects. METHODS:A total of 1000 consecutive patients, who had all been admitted for interventional treatment of symptomatic coronary artery disease, were retrospectively analysed. RESULTS:Elderly p...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Previous reports on patients with radiofrequency catheter ablation (RFCA) of accessory pathway (AP) and atrial fibrillation (AF) include only short follow-up periods. The aim of this study was to analyze predictors of recurrence of AF in patients after successful RFCA of APs over long term follow-up periods....
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0055
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Late gadolinium enhancement (LGE) by cardiac magnetic resonance (CMR) may reveal myocardial fibrosis which is associated with adverse clinical outcomes in patients undergoing implantable cardioverter-defibrillator (ICD) placement. At the same time, transmural LGE in the posterolateral wall is related to nonr...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2020.0009
更新日期:2020-02-10 00:00:00
abstract:BACKGROUND:AFTER (Atrial Fibrillation in Turkey: Epidemiologic Registry) is a prospective, multicenter study designed with the aim of describing the prevalence and epidemiology of AF practice in Turkey. This study aims to evaluate stroke risk in non-valvular atrial fibrillation (AF) and anticoagulant drug utilization w...
journal_title:Cardiology journal
pub_type: 杂志文章,多中心研究
doi:10.5603/CJ.a2013.0055
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Objective of this study was to make an assessment of standard functional and defor-mation parameters (strain) in patients after transcatheter aortic valve replacement (TAVR) by cardiac magnetic resonance imaging (CMR) and the evaluation of their prognostic impact. METHODS:Patients undergoing TAVR received C...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0121
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:In those without symptoms of coronary artery disease (CAD), the incidence of coronary events is still high. The aim of this study was to evaluate whether flow mediated dilatation (FMD) is a useful tool in identifying those with CAD in who are under 45 years of age. METHODS AND RESULTS:Seventy five men below...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Antiplatelet therapy has proven beneficial in the treatment of cardiovascular disease. Proton pump inhibitors (PPIs) are commonly used for gastroprotection in patients receiving antiplatelet therapy. Several trials have been carried out to establish interactions between PPIs, clopidogrel and soluble formulat...
journal_title:Cardiology journal
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2009-01-01 00:00:00
abstract::Despite advances in pharmacological treatments aimed at a neurohormonal blockade for heart failure, there is still a growing number of patients with advanced symptoms who suffer significant morbidity and mortality. At present the most effective cure for end-stage congestive heart failure is cardiac transplantation. Th...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Primary percutaneous coronary intervention (PCI) is recommended for ST-segment elevation myocardial infarction (STEMI) patients even when the patient must be transported to a PCI-capable hospital. This study aimed to evaluate the long-term clinical outcomes of STEMI patients who were transferred for primary ...
journal_title:Cardiology journal
pub_type: 杂志文章,多中心研究
doi:10.5603/CJ.a2016.0003
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Anthracycline-induced cardiotoxicity remains a significant and unresolved issue in patients receiving chemotherapy. The aim of this study was to evaluate left ventricular (LV) twisting function by three-dimensional speckle tracking echocardiography (3D-STE) in patients with lymphoma after anthracycline thera...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0035
更新日期:2017-01-01 00:00:00
abstract::Dysautonomic syndromes are very common clinical conditions with different presentations and a wide spectrum of mechanisms. Many non-pharmacological and pharmacological interventions have been recommended to treat dysautonomic patients along these years, but the majority of them were not supported by multicenter contro...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:10.5603/CJ.2014.0093
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Common genetic polymorphisms at chromosome 4q25 were associated with increased susceptibility to atrial fibrillation (AF). However, it remained controversial whether these variants could be used as risk predictors for AF recurrence after catheter ablation. We therefore performed a metaanalysis to quantify th...
journal_title:Cardiology journal
pub_type: 杂志文章,meta分析,评审
doi:10.5603/CJ.a2017.0143
更新日期:2018-01-01 00:00:00
abstract::n/a - brief communication. ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2019.0099
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Concomitant thyroid and heart disease are frequently encountered in clinical practice. There are many studies evaluating thyroid function in acute and critical conditions. Information on thyroid dysfunction in ST-segment elevation myocardial infarction (STEMI) is limited; its correlation with short and long-...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2013.0108
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Pulmonary arterial hypertension is of importance in congenital cardiac surgery as being a significant cause of morbidity and mortality. Although therapy options are limited, inhaled nitric oxide (NO) is used as a standard therapy. The present study aimed to compare inhaled NO and aerosolized iloprost in chil...
journal_title:Cardiology journal
pub_type: 杂志文章,随机对照试验
doi:10.5603/cj.2012.0070
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Myocardial dysfunction needing inotropic support is a typical complication after on-pump cardiac surgery. In this study, we evaluate the effect of milrinone on patients with ventricular dysfunction undergoing coronary artery bypass graft (CABG). METHODS:Seventy patients with impaired left ventricular functi...
journal_title:Cardiology journal
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate the feasibility of the use of a quadripolar left ventricular (LV) lead for cardiac resynchronization therapy and to compare its acute and mid-term outcomes with those obtained with bipolar leads. Cardiac resynchronization exhibits a high incidence of problems involvi...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2012.0087
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:The aim of this project was to study changes in QRS amplitude in junior female athletes during the initial twenty-one months of competitive training programme in aerobic gymnastics. METHODS:Somatometric parameters, heart rate (HR), blood pressure (BP) and 12-lead ECGs were recorded in 12 female athletes, ag...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Acute myocardial infarction (AMI) due to the occlusion of the left main coronary artery (LMCA) is a rare but serious condition in the era of percutaneus coronary intervention (PCI). Even more rare is AMI involved with both LMCA and its branches like trifurcartion or bifurcation: this is challenging for interventional ...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::Cardiac resynchronization therapy (CRT) is an important advance for the treatment of end-stage heart failure (HF). About 15-50% of HF is complicated by atrial fibrillation (AF), associated with worsened outcomes. The presence of AF may interfere with optimal delivery of CRT due to competition with biventricular (BiV) ...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The authors analyzed data from Polish national POL-TAVI registry in terms of paravalvular leak (PVL) occurrence after transcatheter aortic valve implantation (TAVI) and its impact on clinical outcomes. METHODS:A total of 331 patients with severe aortic stenosis underwent TAVI (Edwards Sapien, n = 141; CoreV...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2015.0071
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Although many thromboembolism risk factors are well defined, formation of thrombus or dense spontaneous contrast (sludge) in the left atrium remains enigmatic and confounding. Exclusion of the thrombus is extremely important with respect to planned reversal of sinus rhythm. Data regarding the routine transes...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2019.0056
更新日期:2019-06-21 00:00:00
abstract::Pulmonary hypertension (PH) is a rare and devastating disease characterized by progressive increases in pulmonary arterial pressure and pulmonary vascular resistance, which eventually leads to right ventric-ular failure and death. Pulmonary arterial hypertension (PAH) (World Health Organization Group I), a subset of P...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0096
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to compare risk predicted using available risk scores and actual outcomes in patients with left main coronary artery disease undergoing percutaneous coronary intervention with stent implantation (PCI LM). METHODS:We studied 204 patients treated with elective or emergent coronar...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Aspirin remains the mainstay of anti-platelet therapy in cardiac patients. However, if a patient is allergic to aspirin and dual anti-platelet therapy is indicated - such as with percutaneous coronary intervention (PCI), then there is no clear guidance. One possibility is aspirin desensitization. A variety o...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.2013.0025
更新日期:2013-01-01 00:00:00